公开(公告)号：US20220411871A1

公开(公告)日：2022-12-29

申请号：US17751201

申请日：2022-05-23

Applicant: Sequenom, Inc.

Inventor： Taylor Jacob Jensen ,  Jennifer Geis ,  Sung Kyun Kim ,  Cosmin Deciu ,  Mathias Ehrich

IPC: C12Q1/6883 ,  G16B25/00 ,  G16B45/00 ,  G16B25/10 ,  G16B25/20

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US11365447B2

公开(公告)日：2022-06-21

申请号：US15124324

申请日：2015-03-12

Applicant: SEQUENOM, INC.

Inventor： Taylor Jacob Jensen ,  Jennifer Geis ,  Sung Kyun Kim ,  Cosmin Deciu ,  Mathias Ehrich

IPC: C12Q1/6883 ,  G16B25/00 ,  G16B45/00 ,  G16B25/10 ,  G16B25/20 ,  H01J49/16

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations. In particular the invention relates to methods and kits for detecting aneuploidy of a fetal chromosome by determining the amounts of differentially methylated regions in each of chromosomes 13, 18 and 21 in circulating cell-free nucleic acid from a human pregnant female.

公开(公告)号：US20170342477A1

公开(公告)日：2017-11-30

申请号：US15607235

申请日：2017-05-26

Applicant: Sequenom, Inc.

Inventor： Taylor Jacob Jensen ,  Mathias Ehrich ,  Dirk van den Boom ,  John Allen Tynan ,  Sung Kyun Kim ,  Timothy S. Burcham ,  Christopher K. Ellison ,  Youting Sun

IPC: C12Q1/68 ,  C40B30/02 ,  G06F19/22 ,  G06F19/20

CPC classification number: C12Q1/6858 ,  C12Q1/6844 ,  C12Q1/6853 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/156 ,  C12Q2600/16 ,  G16B25/00 ,  G16B30/00 ,  G16B35/00 ,  G16C20/60 ,  G16H15/00 ,  G16H50/30 ,  C12Q2537/143 ,  C12Q2537/16 ,  C12Q2537/165 ,  C12Q2545/114

Abstract: Technology provided herein relates in part to methods, processes, machines and apparatuses for detecting genetic variations. In some embodiments, the technology is related to non-invasive assessment of aneuploidies.

公开(公告)号：US11929146B2

公开(公告)日：2024-03-12

申请号：US16544316

申请日：2019-08-19

Applicant: SEQUENOM, INC.

Inventor： Sung Kim ,  Taylor Jacob Jensen ,  Mathias Ehrich

IPC: G16B20/20 ,  G16B20/00 ,  G16B20/10 ,  G16B30/00 ,  G16B30/10 ,  G16B30/20

CPC classification number: G16B20/20 ,  G16B20/00 ,  G16B20/10 ,  G16B30/00 ,  G16B30/10 ,  G16B30/20

Abstract: Provided herein are methods, processes, systems, machines and apparatuses for non-invasive assessment of chromosome alterations.

公开(公告)号：US11437121B2

公开(公告)日：2022-09-06

申请号：US15959880

申请日：2018-04-23

Applicant: SEQUENOM, INC.

Inventor： Cosmin Deciu ,  Zeljko Dzakula ,  Mathias Ehrich ,  Taylor Jacob Jensen

IPC: G16B20/20 ,  G16B20/00 ,  G16B30/00 ,  C12Q1/6883 ,  G16B20/40 ,  G16B30/20 ,  G16B30/10 ,  G16B20/10

Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US10438691B2

公开(公告)日：2019-10-08

申请号：US15026939

申请日：2014-10-03

Applicant: SEQUENOM, INC.

Inventor： Sung Kim ,  Taylor Jacob Jensen ,  Mathias Ehrich

IPC: G16B30/00 ,  G16B20/00

Abstract: Provided herein are methods, processes, systems, machines and apparatuses for non-invasive assessment of chromosome alterations.

公开(公告)号：US20200208212A1

公开(公告)日：2020-07-02

申请号：US16821863

申请日：2020-03-17

Applicant: Sequenom, Inc.

Inventor： Mathias Ehrich ,  Anders Olof Herman Nygren ,  Taylor Jacob Jensen

IPC: C12Q1/6869 ,  C12Q1/6888 ,  C12Q1/6809 ,  C12Q1/6806 ,  C12Q1/6804

Abstract: Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies.

公开(公告)号：US09984198B2

公开(公告)日：2018-05-29

申请号：US13797930

申请日：2013-03-12

Applicant: SEQUENOM, INC.

Inventor： Cosmin Deciu ,  Zeljko Dzakula ,  Mathias Ehrich ,  Taylor Jacob Jensen

IPC: G06F19/18 ,  C12Q1/68 ,  G06F19/22

CPC classification number: G06F19/18 ,  C12Q1/6883 ,  C12Q2600/156 ,  G06F19/22

Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US11060145B2

公开(公告)日：2021-07-13

申请号：US14772544

申请日：2014-03-13

Applicant: SEQUENOM, INC.

Inventor： Taylor Jacob Jensen ,  Mathias Ehrich

IPC: C12Q1/6883 ,  C12Q1/6811

Abstract: Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

公开(公告)号：US20130325360A1

公开(公告)日：2013-12-05

申请号：US13797930

申请日：2013-03-12

Applicant: SEQUENOM, INC.

Inventor： COSMIN DECIU ,  Zeljko Dzakula ,  Mathias Ehrich ,  Taylor Jacob Jensen

IPC: G06F19/18

CPC classification number: G06F19/18 ,  C12Q1/6883 ,  C12Q2600/156 ,  G06F19/22

Abstract: Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.

Abstract translation: 本文提供了用于遗传变异的非侵入性评估的方法，过程和装置。