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公开(公告)号：US20070190640A1
公开(公告)日：2007-08-16
申请号：US11655943
申请日：2007-01-22
IPC分类号： C12M3/00
CPC分类号： G01N33/54333 , B82Y15/00 , B82Y25/00 , H01F1/0054
摘要： A device and a method are disclosed for the detection and/or for the quantification of an analyte. In at least one embodiment, the device includes a basic matrix and magnetized nanoparticles, which are arranged in moveable fashion in or at the basic matrix and to which catcher molecules that bind specifically to the analyte are anchored. Further, the mobility of the nanoparticle in the basic matrix can be influenced by a binding of the analyte to be detected to the catcher molecules and can be read out magnetically.
摘要翻译： 公开了用于检测和/或定量分析物的装置和方法。 在至少一个实施方案中，该装置包括基本基质和磁化纳米颗粒，其以可移动的方式设置在碱性基质中或基本基质上，并且特异性结合分析物的捕获剂分子被锚固。 此外，纳米颗粒在碱性基质中的迁移率可能受待检测的分析物与捕获剂分子的结合的影响，并且可以磁性地读出。
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2.发明申请公开(公告)号：US20070003959A1
公开(公告)日：2007-01-04
申请号：US11474454
申请日：2006-06-26
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
CPC分类号： C12Q1/6876 , B82Y5/00 , B82Y10/00 , Y10T436/143333
摘要： Oligonucleotide arrangements are disclosed which, in each case, have at least two oligonucleotide sequences linked via at least one spacer. A process is disclosed using the oligonucleotide arrangements for the amplification and/or detection of nucleic acid sequences with formation of crosslinked conglomerates. The process can be used, for example, for the sensitive, simple and inexpensive detection of nucleic acid sequences.
摘要翻译： 公开了寡核苷酸排列，其在每种情况下具有通过至少一个间隔物连接的至少两个寡核苷酸序列。 公开了使用寡核苷酸排列来扩增和/或检测与形成交联聚集体的核酸序列的方法。 该方法可用于例如核酸序列的灵敏，简单且廉价的检测。
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3.发明授权Apparatus for processing a sample comprising a biochip and reagents embedded in a biodegradable material, and processes thereof 有权用于处理包含生物芯片和嵌入生物可降解材料中的试剂的样品的装置及其工艺公开(公告)号：US08551424B2
公开(公告)日：2013-10-08
申请号：US11594938
申请日：2006-11-09
IPC分类号： G01N33/544 , G01N33/00 , A61F2/00
CPC分类号： G01N1/42 , G01N2035/00148 , Y10T436/25
摘要： An apparatus is disclosed for processing a sample which stores processing reagents required for processing in a dry form. The processing reagents are covered by a biologically degradable medium or embedded in said biologically degradable medium.
摘要翻译： 公开了一种用于处理以干燥形式存储处理所需的处理试剂的样品的装置。 处理试剂被生物降解介质覆盖或嵌入所述生物降解介质中。
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公开(公告)号：US08263331B2
公开(公告)日：2012-09-11
申请号：US11655943
申请日：2007-01-22
CPC分类号： G01N33/54333 , B82Y15/00 , B82Y25/00 , H01F1/0054
摘要： A device and a method are disclosed for the detection and/or for the quantification of an analyte. In at least one embodiment, the device includes a basic matrix and magnetized nanoparticles, which are arranged in moveable fashion in or at the basic matrix and to which catcher molecules that bind specifically to the analyte are anchored. Further, the mobility of the nanoparticle in the basic matrix can be influenced by a binding of the analyte to be detected to the catcher molecules and can be read out magnetically.
摘要翻译： 公开了用于检测和/或定量分析物的装置和方法。 在至少一个实施方案中，该装置包括基本基质和磁化纳米颗粒，其以可移动的方式设置在碱性基质中或基本基质上，并且特异性结合分析物的捕获剂分子被锚固。 此外，纳米颗粒在碱性基质中的迁移率可能受待检测的分析物与捕获剂分子的结合的影响，并且可以磁性地读出。
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5.发明授权Module for processing a biological sample, biochip kit, and use of the module 有权用于处理生物样品的模块，生物芯片套件和模块的使用公开(公告)号：US08771609B2
公开(公告)日：2014-07-08
申请号：US11653230
申请日：2007-01-16
IPC分类号： B01L3/00
CPC分类号： G01N1/40 , B01L3/502715 , B01L3/565 , B01L2200/027 , B01L2300/0816 , G01N35/0098 , Y10T436/2575
摘要： A module for processing a biological sample for an analysis test is disclosed. The processing module includes, in at least one embodiment, an interface at which the processing module can be connected to a cartridge with a lab-on-a-chip, in which cartridge the analysis steps are carried out. A biochip kit is also disclosed. In at least one embodiment, the biochip kit includes one or more processing modules which are intended for different sample materials and which can be connected to the same cartridge type.
摘要翻译： 公开了用于处理用于分析测试的生物样品的模块。 处理模块在至少一个实施例中包括接口，在该界面处，处理模块可以与芯片上的实验室连接，其中进行分析步骤。 还公开了一种生物芯片套件。 在至少一个实施例中，生物芯片套件包括一个或多个处理模块，其用于不同的样品材料并且可以连接到相同的盒式。
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公开(公告)号：US20110207619A1
公开(公告)日：2011-08-25
申请号：US12448015
申请日：2007-11-29
申请人： Thomas Ehben , Mitja Schonecke , Christian Zilch
发明人： Thomas Ehben , Mitja Schonecke , Christian Zilch
CPC分类号： B01L9/527 , B01L2300/021 , G01N35/04
摘要： An arrangement is provided in at least one embodiment, having a magazine for supplying a plurality of microfluidic devices. The microfluidic devices each contain at least one element/device for binding at least one biological molecule, wherein the at least one element/device for binding the at least one biological molecule can be moved relative to the microfluidic device. A sample presumably containing biological molecules to be examined is introduced into the microfluidic device. The biological molecule to be examined is bound by the at least one element/device for binding the biological molecule. In at least one embodiment, the at least one element/device for binding the at least one biological molecule, or the substrate-molecule complex, can then be moved in the microfluidic device, e.g. in accordance with a predetermined reaction sequence, for example by means of a magnetic field. The microfluidic device is transported through the arrangement.
摘要翻译： 在至少一个实施例中提供了一种布置，其具有用于供应多个微流体装置的盒。 微流体装置各自包含用于结合至少一个生物分子的至少一个元件/装置，其中用于结合至少一个生物分子的至少一个元件/装置可以相对于微流体装置移动。 将含有待检测的生物分子的样品引入微流体装置。 待检测的生物分子被至少一个用于结合生物分子的元件/装置结合。 在至少一个实施方案中，用于结合至少一个生物分子或底物 - 分子复合物的至少一种元件/装置然后可以在微流体装置中移动，例如， 根据预定的反应顺序，例如借助于磁场。 微流体装置通过该装置输送。
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公开(公告)号：US07932082B2
公开(公告)日：2011-04-26
申请号：US11599424
申请日：2006-11-15
申请人： Klaus Abraham-Fuchs , Thomas Ehben , Walter Gumbrecht , Peter Paulicka , Sebastian Schmidt , Manfred Stanzel , Christian Zilch
发明人： Klaus Abraham-Fuchs , Thomas Ehben , Walter Gumbrecht , Peter Paulicka , Sebastian Schmidt , Manfred Stanzel , Christian Zilch
CPC分类号： B01L3/502715 , A61B10/0051 , A61B10/0096 , B01L3/502738 , B01L3/502761 , B01L3/5029 , B01L2200/027 , B01L2300/042 , B01L2400/0478 , B01L2400/0633 , G01N2001/028
摘要： A device is disclosed for extracting a smear sample. The device includes a cavity, into which a sample carrier carrying a smear sample can be introduced. Liquid can be introduced into the cavity through at least one liquid feed connected to the cavity, and the liquid can be removed from the cavity through at least one liquid discharge connected to the cavity.
摘要翻译： 公开了一种用于提取涂片样品的装置。 该装置包括可以引入携带涂片样品的样品载体的空腔。 可以通过连接到空腔的至少一个液体进料将液体引入空腔中，并且可以通过连接到空腔的至少一个液体排出物从腔中去除液体。
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公开(公告)号：US20070274840A1
公开(公告)日：2007-11-29
申请号：US11637781
申请日：2006-12-13
IPC分类号： B60L9/16
CPC分类号： H02K44/04
摘要： A MHD pump, in an example embodiment, includes a fluid channel, an electrode pair that generates an electric field in the fluid channel, and an electromagnet that generates a magnetic field, the magnetic field lines of which intersect the electric field lines of the electric field. The fluid channel is defined in an exchangeable cassette.
摘要翻译： 在示例性实施例中，MHD泵包括流体通道，在流体通道中产生电场的电极对，以及产生磁场的电磁体，其磁场线与电气线的电场线相交 领域。 流体通道限定在可更换的盒中。
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9.发明申请公开(公告)号：US20100323360A1
公开(公告)日：2010-12-23
申请号：US12805878
申请日：2010-08-23
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
CPC分类号： C12Q1/6876 , B82Y5/00 , B82Y10/00 , Y10T436/143333
摘要： Oligonucleotide arrangements are disclosed which, in each case, have at least two oligonucleotide sequences linked via at least one spacer. A process is disclosed using the oligonucleotide arrangements for the amplification and/or detection of nucleic acid sequences with formation of crosslinked conglomerates. The process can be used, for example, for the sensitive, simple and inexpensive detection of nucleic acid sequences.
摘要翻译： 公开了寡核苷酸排列，其在每种情况下具有通过至少一个间隔物连接的至少两个寡核苷酸序列。 公开了使用寡核苷酸排列来扩增和/或检测与形成交联聚集体的核酸序列的方法。 该方法可用于例如核酸序列的灵敏，简单且廉价的检测。
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10.发明申请Device and Method for Preparing a Sample for an Analysis and Device and Method for Analyzing a Sample 审中-公开用于分析样品准备样品的装置和方法以及用于分析样品的方法公开(公告)号：US20090035746A1
公开(公告)日：2009-02-05
申请号：US11922879
申请日：2006-06-21
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
CPC分类号： B01L3/502761 , B01L7/52 , B01L2200/0647 , B01L2300/0816 , B01L2300/087 , B01L2300/1822 , B01L2400/043 , G01N35/0098
摘要： A device and method are disclosed for preparing a sample for an analysis and a device and method are disclosed for analyzing a sample. In at least one embodiment, a device is disclosed for preparing a sample for analysis including means for binding at lest one biological structure of the sample, means for releasing at least one biological molecule contained in the at least one structure, and means for binding the at least one released molecule. The means for binding the at least one structure and the means for binding the at least one molecule can move.
摘要翻译： 公开了一种用于制备用于分析的样品的装置和方法，并且公开了用于分析样品的装置和方法。 在至少一个实施方案中，公开了用于制备用于分析的样品的装置，包括用于结合样品的至少一个生物结构的装置，用于释放至少一个结构中包含的至少一个生物分子的装置，以及用于结合 至少一个释放的分子。 用于结合所述至少一种结构的方法和用于结合至少一种分子的方法可移动。
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