System and method of treatment for insomnia and occasional sleeplessness
    1.
    发明授权
    System and method of treatment for insomnia and occasional sleeplessness 有权
    治疗失眠和偶尔失眠的系统和方法

    公开(公告)号:US08523758B1

    公开(公告)日:2013-09-03

    申请号:US12113916

    申请日:2008-05-01

    IPC分类号: A61M21/00

    摘要: A system configured to provide breathing cues to a patient to alleviate insomnia or sleeplessness. In one embodiment, the system comprises a pressure support apparatus, a patient monitor, and a processor. The pressure support apparatus is configured to provide a pressurized flow of gas for delivery to an airway of the patient. The patient monitor configured to generate one or more signals that convey information related to one or more physiological functions of the patient. The processor in operative communication with each of the pressure support apparatus and the patient monitor. The processor is configured (i) to determine whether the patient is asleep or awake based at least in part on the one or more signals generated by the patient monitor, and (ii) to control the pressure support apparatus such that if the patient is determined to be awake, one or more properties of the flow of gas are varied according to a first predetermined algorithm designed to provide breathing cues to the patient that prompt the patient to breathe at a target breathing rate.

    摘要翻译: 一种被配置为向患者提供呼吸提示以减轻失眠或失眠的系统。 在一个实施例中,该系统包括压力支持装置,患者监视器和处理器。 压力支持装置构造成提供用于输送到患者的气道的气体的加压气流。 所述患者监视器被配置为生成一个或多个信号,所述信号传达与患者的一个或多个生理功能相关的信息。 处理器与每个压力支持装置和患者监视器进行操作性通信。 所述处理器被配置为:(i)至少部分地基于由所述患者监视器产生的一个或多个信号来确定所述患者是否睡着或唤醒,以及(ii)控制所述压力支持设备,使得如果所述患者被确定 为了清醒,气体流动的一个或多个性质根据设计用于向患者提供呼吸提示的第一预定算法而改变,以促使患者以目标呼吸速率呼吸。

    Method and apparatus for hypoglossal nerve stimulation
    4.
    发明授权
    Method and apparatus for hypoglossal nerve stimulation 有权
    舌下神经刺激的方法和装置

    公开(公告)号:US08024044B2

    公开(公告)日:2011-09-20

    申请号:US12644076

    申请日:2009-12-22

    IPC分类号: A61N1/18

    摘要: A method of treating sleep disordered breathing in a patient includes the steps of monitoring the patient for a pre-inspiratory drive signal indicative of the breathing cycle by sensing electroneurogram activity of a hypoglossal nerve of the patient; and electrically stimulating the hypoglossal nerve of the patient following each detection of the pre-inspiratory drive signal. An implantable apparatus for stimulating a hypoglossal nerve of a patient for the treatment of sleep disordered breathing includes an electrode positioned at least partially around the hypoglossal nerve with a monitoring contact and a stimulation contact and a controller operatively coupled to the monitoring contact and the stimulation contact. The monitoring contact monitors the electroneurogram activity of the hypoglossal nerve for a pre-inspiratory drive signal indicative of the onset of inspiration and sends a signal to the controller which in turn causes the stimulating electrode to electrically stimulate the hypoglossal nerve.

    摘要翻译: 一种治疗患者睡眠呼吸障碍的方法包括以下步骤:通过感测患者的舌下神经的电图活动来监测患者的吸气前驱动信号,以指示呼吸周期; 并且在每次检测到吸气前驱动信号之后电刺激患者的舌下神经。 用于刺激患者的舌下神经以用于治疗睡眠无序呼吸的可植入装置包括至少部分地围绕舌下神经定位的电极,其具有监测接触和刺激接触以及可操作地耦合到监测接触和刺激接触的控制器 。 监测接触器监测舌下神经的电子图像活动,用于指示吸气开始的吸气前驱动信号,并向控制器发送信号,控制器又引起刺激电极电刺激舌下神经。

    Method and apparatus for hypoglossal nerve stimulation
    5.
    发明授权
    Method and apparatus for hypoglossal nerve stimulation 有权
    舌下神经刺激的方法和装置

    公开(公告)号:US07660632B2

    公开(公告)日:2010-02-09

    申请号:US11770202

    申请日:2007-06-28

    IPC分类号: A61N1/18

    摘要: A method of treating sleep disordered breathing in a patient includes the steps of monitoring the patient for a pre-inspiratory drive signal indicative of the breathing cycle by sensing electroneurogram activity of a hypoglossal nerve of the patient; and electrically stimulating the hypoglossal nerve of the patient following each detection of the pre-inspiratory drive signal. An implantable apparatus for stimulating a hypoglossal nerve of a patient for the treatment of sleep disordered breathing includes an electrode positioned at least partially around the hypoglossal nerve with a monitoring contact and a stimulation contact and a controller operatively coupled to the monitoring contact and the stimulation contact. The monitoring contact monitors the electroneurogram activity of the hypoglossal nerve for a pre-inspiratory drive signal indicative of the onset of inspiration and sends a signal to the controller which in turn causes the stimulating electrode to electrically stimulate the hypoglossal nerve.

    摘要翻译: 一种治疗患者睡眠呼吸障碍的方法包括以下步骤:通过感测患者的舌下神经的电图活动来监测患者的吸气前驱动信号,以指示呼吸周期; 并且在每次检测到吸气前驱动信号之后电刺激患者的舌下神经。 用于刺激患者的舌下神经以用于治疗睡眠无序呼吸的可植入装置包括至少部分地围绕舌下神经定位的电极,其具有监测接触和刺激接触以及可操作地耦合到监测接触和刺激接触的控制器 。 监测接触器监测舌下神经的电子图像活动,用于指示吸气开始的吸气前驱动信号,并向控制器发送信号,控制器又引起刺激电极电刺激舌下神经。

    Method and Apparatus for Hypoglossal Nerve Stimulation
    6.
    发明申请
    Method and Apparatus for Hypoglossal Nerve Stimulation 有权
    低神经刺激的方法和装置

    公开(公告)号:US20080161877A1

    公开(公告)日:2008-07-03

    申请号:US11770202

    申请日:2007-06-28

    IPC分类号: A61N1/36

    摘要: A method of treating sleep disordered breathing in a patient includes the steps of monitoring the patient for a pre-inspiratory drive signal indicative of the breathing cycle by sensing electroneurogram activity of a hypoglossal nerve of the patient; and electrically stimulating the hypoglossal nerve of the patient following each detection of the pre-inspiratory drive signal. An implantable apparatus for stimulating a hypoglossal nerve of a patient for the treatment of sleep disordered breathing includes an electrode positioned at least partially around the hypoglossal nerve with a monitoring contact and a stimulation contact and a controller operatively coupled to the monitoring contact and the stimulation contact. The monitoring contact monitors the electroneurogram activity of the hypoglossal nerve for a pre-inspiratory drive signal indicative of the onset of inspiration and sends a signal to the controller which in turn causes the stimulating electrode to electrically stimulate the hypoglossal nerve.

    摘要翻译: 一种治疗患者睡眠呼吸障碍的方法包括以下步骤:通过感测患者的舌下神经的电图活动来监测患者的吸气前驱动信号,以指示呼吸周期; 并且在每次检测到吸气前驱动信号之后电刺激患者的舌下神经。 用于刺激患者的舌下神经以用于治疗睡眠无序呼吸的可植入装置包括至少部分地围绕舌下神经定位的电极,其具有监测接触和刺激接触以及可操作地耦合到监测接触和刺激接触的控制器 。 监测接触器监测舌下神经的电子图像活动,用于指示吸气开始的吸气前驱动信号,并向控制器发送信号,控制器又引起刺激电极电刺激舌下神经。

    Systems and methods for controlling breathing rate
    7.
    发明授权
    Systems and methods for controlling breathing rate 有权
    控制呼吸频率的系统和方法

    公开(公告)号:US07556038B2

    公开(公告)日:2009-07-07

    申请号:US11836292

    申请日:2007-08-09

    IPC分类号: A62B7/00

    摘要: A method and corresponding system for providing breathing cues includes monitoring respiration of a user and determining a user breathing frequency including an inspiration portion and an expiration portion of the breathing, supplying a high positive air pressure to the user during the inspiration portion and a low positive air pressure during the expiration portion in substantial synchronicity with the user's respiration, comparing the user breathing frequency with a target breathing frequency, and when the user breathing frequency is greater than the target breathing frequency, increasing, in a predetermined manner, a time over which the high positive air pressure is supplied to the user, and adjusting a time over which the low positive pressure air pressure is supplied to the user.

    摘要翻译: 一种用于提供呼吸线索的方法和相应的系统包括监测用户的呼吸并确定用户呼吸频率,其包括呼吸的吸气部分和呼气部分,在吸气部分期间向使用者提供高正空气压力,而低阳性 呼气期间的空气压力与使用者的呼吸大致同步,将用户呼吸频率与目标呼吸频率进行比较,并且当用户呼吸频率大于目标呼吸频率时,以预定方式增加时间 向用户提供高正空气压力,并且调节向使用者提供低正压空气压力的时间。

    Systems and Methods for Controlling Breathing Rate
    8.
    发明申请
    Systems and Methods for Controlling Breathing Rate 有权
    控制呼吸速率的系统和方法

    公开(公告)号:US20080035147A1

    公开(公告)日:2008-02-14

    申请号:US11836292

    申请日:2007-08-09

    IPC分类号: A62B7/00 A61M16/00

    摘要: A method and corresponding system for providing breathing cues includes monitoring respiration of a user and determining a user breathing frequency including an inspiration portion and an expiration portion of the breathing, supplying a high positive air pressure to the user during the inspiration portion and a low positive air pressure during the expiration portion in substantial synchronicity with the user's respiration, comparing the user breathing frequency with a target breathing frequency, and when the user breathing frequency is greater than the target breathing frequency, increasing, in a predetermined manner, a time over which the high positive air pressure is supplied to the user, and adjusting a time over which the low positive pressure air pressure is supplied to the user.

    摘要翻译: 一种用于提供呼吸线索的方法和相应的系统包括监测用户的呼吸并确定用户呼吸频率,其包括呼吸的吸气部分和呼气部分,在吸气部分期间向使用者提供高正空气压力,而低阳性 呼气期间的空气压力与使用者的呼吸大致同步,将用户呼吸频率与目标呼吸频率进行比较,并且当用户呼吸频率大于目标呼吸频率时,以预定方式增加时间 向用户提供高正空气压力,并且调节向使用者提供低正压空气压力的时间。