公开(公告)号：US20220395838A1

公开(公告)日：2022-12-15

申请号：US17838807

申请日：2022-06-13

Applicant: University of Washington

Inventor： Paul Yager ,  Steven Bennett ,  Erin K. Heiniger ,  Sujatha Kumar ,  Kamal Girish Shah

IPC: B01L7/00 ,  B01L3/00 ,  C12Q1/6806

Abstract: Fluidic devices, systems, and methods for analyzing an analyte are described. In an embodiment, the fluidic devices include a housing defining a lysis chamber shaped to receive a biological sample; a lysis buffer storage chamber disposed within the housing and carrying a lysis buffer configured to lyse cells of the biological sample; a cap configured to cooperatively couple to the housing; a compressor configured to compress the lysis buffer storage chamber and expel the lysis buffer from the lysis buffer storage chamber and into the lysis chamber when the cap is uncoupled from the housing; and a porous membrane in selective fluidic communication with the lysis chamber.

公开(公告)号：US20220371006A1

公开(公告)日：2022-11-24

申请号：US17761138

申请日：2020-10-01

Applicant: University of Washington

Inventor： Paul Yager ,  Steven Bennett ,  Sujatha Kumar ,  Kamal Girish Shah ,  Erin K. Heiniger

IPC: B01L3/00 ,  G01N1/14

Abstract: An apparatus, system, and method for filtering and assaying a fluid sample are described. In an embodiment, the apparatus includes a filtration unit comprising: a filter bracket shaped to removably couple with a fluid sample cup and a vacuum container; and a filter housing cooperatively couplable to the filter bracket and comprising a filter configured to filter fluid passing through the filter bracket; and an assay device shaped to cooperatively couple with the filter housing and comprising a porous matrix positioned to be in fluidic communication with the filter when the filter housing is cooperatively coupled with the assay device.

公开(公告)号：US20200378998A1

公开(公告)日：2020-12-03

申请号：US16887148

申请日：2020-05-29

Applicant: University of Washington

Inventor： Steven Bennett

IPC: G01N35/10

Abstract: The present technology is directed to extraction devices, systems, and methods for controllably withdrawing and transferring fluid samples, such as blood, from a sample collection container to a testing device. For example, some embodiments of the present technology provide fluid extraction devices that include a fluid control module, a housing containing a receiving element and a suction element, and an actuator. To transfer blood from a sample collection container to a testing device, a user places the sample collection container over the receiving element and inserts the testing device into an outlet of the fluid control module. The user then pushes a lever or otherwise actuates the actuator, which automatically withdraws a predetermined volume of blood from the sample collection container and transfers it to the testing device positioned at the outlet of the fluid control module.

公开(公告)号：US20240280501A1

公开(公告)日：2024-08-22

申请号：US18567512

申请日：2022-06-13

Applicant: UNIVERSITY OF WASHINGTON ,  UbiDX, Inc.

Inventor： Paul Yager ,  Steven Bennett ,  Kamal Girish Shah ,  Katherine Sharadin

IPC: G01N21/88 ,  G01N15/1434

CPC classification number: G01N21/8806 ,  G01N15/1434 ,  G01N2021/8816

Abstract: A base and a diagnostic system for analyzing a sample is described herein. In an embodiment, the system includes a cartridge and a base configured to couple with the cartridge. In an embodiment, the cartridge is configured to hold a sample, and comprises a transparent viewing field positioned in the detection zone. In an embodiment, the base includes a detection component including a window to allow a light from a detection zone of the cartridge to enter the base, and a photodetector positioned to receive the light through the window and configured to generate a signal based on the light received, a plurality of light sources that emit one or more illumination lights onto the detection zone, and a controller communicatively configured to illuminate the detection zone with the plurality of light sources, and generate a detection signal with the photodetector based on the light received.

公开(公告)号：US11604204B2

公开(公告)日：2023-03-14

申请号：US16887148

申请日：2020-05-29

Applicant: University of Washington

Inventor： Steven Bennett

IPC: G01N35/10 ,  G01N1/14 ,  A61J1/20 ,  A61J1/22 ,  B01L3/02 ,  G01N1/00 ,  A61B5/15 ,  A61B10/00 ,  A61J1/14

Abstract: The present technology is directed to extraction devices, systems, and methods for controllably withdrawing and transferring fluid samples, such as blood, from a sample collection container to a testing device. For example, some embodiments of the present technology provide fluid extraction devices that include a fluid control module, a housing containing a receiving element and a suction element, and an actuator. To transfer blood from a sample collection container to a testing device, a user places the sample collection container over the receiving element and inserts the testing device into an outlet of the fluid control module. The user then pushes a lever or otherwise actuates the actuator, which automatically withdraws a predetermined volume of blood from the sample collection container and transfers it to the testing device positioned at the outlet of the fluid control module.