摘要:
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.
摘要:
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.
摘要:
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof
摘要:
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound or the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.
摘要:
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, R2 is hydrogen, lower alkyl or the like, n is 1 or 2, X is lower alkylene, lower alkenylene, arylene, cycloalkylene or the like, Y is CONR7, CSNR7, NR7CO, NR7CS or the like, Z is lower alkyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl or the like and R7 is hydrogen or lower alkyl, prodrug, pharmaceutically acceptable salt or solvate thereof.
摘要:
A process for the preparation of Compound (I) comprising reacting Compound (II) with a base in an aprotic solvent, which is represented by the following scheme: wherein R1 and R2 are each independently lower alkyl.
摘要:
An optical communication module includes a control unit and a nonvolatile memory. The control unit detects an abnormality of the optical communication module, generates log information regarding the detected abnormality, and writes the log information in the nonvolatile memory. After the number of times the log information has been written in the nonvolatile memory has reached a predetermined number of times, the control unit does not write log information in the nonvolatile memory. Accordingly, the number of times the nonvolatile memory is permitted to be written can be prevented from considerably decreasing.
摘要:
A recording control unit records program data for a second time period, from the time point the second time period before the lapse of a first time period from the start of recording, not only under a first title but also at a start portion of a second title. A combining unit identifies identical CM portions in the program data recorded redundantly under the first and second titles, connects the portion immediately preceding the start of the identified CM portion of the first title to the portion immediately succeeding the end of the identified CM portion of the second title, to form one title. An editing unit edits the program data to make shorter the length of the combined title, when the time of program data recorded under the combined title exceeds the first time period.
摘要:
A recording time setting process, performed by a data recording and reproduction apparatus capable of readily setting a recording start time and a recording finish time, includes: the step of detecting execution of a meter recording setting mode, the step of detecting an input of recording start position, the step of calculating a time from the recording start position, the step of storing the recording start time in a memory, the step of detecting an input of recording finish position, the step of calculating a time from the recording finish position, the step of calculating a recording time period when the recording finish position is determined, and the step of storing the recording finish time in the memory if the recording time period has not yet been selected for another recording and if the required capacity does not exceed the storage capacity of the HDD.
摘要:
Provided is a method for winding an edgewise coil and a winding device capable of saving time and labor when changing a guide. A guide bar is disposed in contact with the side face of the rectangular conductor bent by the bending jig and the rotation center of the guide bar deviates from the rotation center of a bending jig for bending a rectangular conductor. The guide bar rotates in accordance with the action whereby the bending jig bends the rectangular conductor and supports the outside surface of a coil on the side of rotational direction of the bending jig.