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公开(公告)号：US20200308274A1
公开(公告)日：2020-10-01
申请号：US16836064
申请日：2020-03-31
摘要： The present invention relates to specific antibodies and use thereof, such as for identifying and/or quantifying liraglutide fibrils and/or semaglutide fibrils.
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公开(公告)号：US20230174084A1
公开(公告)日：2023-06-08
申请号：US18074944
申请日：2022-12-05
发明人： Edwin OLSON , Acshi HAGGENMILLER
CPC分类号： B60W50/06 , G06N5/022 , G06F16/2455 , G06F16/2246 , B60W30/18163 , B60W30/143 , B60W60/0015
摘要： An uncertainty-aware framework is presented for high-variance planning problems with multiple dynamic agents. Planning when surrounded by multiple uncertain dynamic agents is hard because one cannot be certain of either the initial states or the future actions of those agents, leading to an exponential explosion in possible futures. Many important real-world problems, such as autonomous driving, fit this model. To address these difficulties, Multi-policy Decision Making (MPDM) and Monte Carlo tree search (MCTS) are combined and a policy tree search performed with marginal action cost estimation and repeated belief particles.
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公开(公告)号：US20090226691A1
公开(公告)日：2009-09-10
申请号：US12397482
申请日：2009-03-04
申请人： Nilesh D. Mankame , John Andrew Shaw , Benjamin Reedlunn , Alan L. Browne , Xiujie Gao , Paul W. Alexander , Jan H. Aase , Nancy L. Johnson , Kenneth A. Strom , Sanjeev M. Naik , Chandra S. Namuduri , Robin Stevenson , William R. Rodgers , John C. Ulicny , Christopher P. Henry , Paul E. Krajewski , Ravindra Brammajyosula
发明人： Nilesh D. Mankame , John Andrew Shaw , Benjamin Reedlunn , Alan L. Browne , Xiujie Gao , Paul W. Alexander , Jan H. Aase , Nancy L. Johnson , Kenneth A. Strom , Sanjeev M. Naik , Chandra S. Namuduri , Robin Stevenson , William R. Rodgers , John C. Ulicny , Christopher P. Henry , Paul E. Krajewski , Ravindra Brammajyosula
CPC分类号： D07B5/00 , D07B1/0673 , D07B2201/2009 , D07B2205/3085 , Y10T428/249922 , D07B2801/10
摘要： A cable adapted for use as an actuator, adaptive structural member, or damper, includes a plurality of longitudinally inter-engaged and cooperatively functioning shape memory alloy wires.
摘要翻译： 适于用作致动器，自适应结构构件或阻尼器的电缆包括多个纵向相互接合和协同工作的形状记忆合金线。
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公开(公告)号：US20240358663A1
公开(公告)日：2024-10-31
申请号：US18657413
申请日：2024-05-07
发明人： David Pinsky , Scott H. Visovatti
IPC分类号： A61K31/185 , A61K31/167 , A61K31/7076 , A61K38/46 , A61K45/06 , A61P9/12
CPC分类号： A61K31/185 , A61K31/167 , A61K31/7076 , A61K38/46 , A61K45/06 , A61P9/12 , C12Y306/01005
摘要： Provided herein are compositions and methods for the treatment of pulmonary arterial hypertension. In particular, compositions and methods are provided that address purinergic dysregulation, the causes thereof, and/or the effect of downstream targets.
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公开(公告)号：US20240350124A1
公开(公告)日：2024-10-24
申请号：US18688522
申请日：2022-08-31
IPC分类号： A61B17/00
CPC分类号： A61B17/00234 , A61B2017/00287 , A61B2017/00367 , A61B2017/00477 , A61B2017/00862 , A61B2017/00938
摘要： A device including a rod with a tip and a channel formed in the tip. The device further includes a containment member including a first end and a second end opposite the first end. The second end is coupled to the tip, and the containment member includes an opening positioned at the first end. An expansion string and a compression string are coupled to the opening of the containment member. The expansion string extends through the channel in the tip.
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公开(公告)号：US12121360B2
公开(公告)日：2024-10-22
申请号：US17368207
申请日：2021-07-06
CPC分类号： A61B5/4088 , A61B5/372 , A61B5/374 , A61B5/378 , A61B5/7221 , A61B5/7264 , A61B5/7267 , A61B5/7282 , A61B5/742 , A61B5/7435 , A61F2/72 , A61F4/00 , G06F3/015 , G09B7/06
摘要： Methods, systems, apparatus, and non-transitory computer readable media are disclosed utilizing brain-computer interfaces (BCIs). Various embodiments are disclosed to allow a user to directly select multiple-choice answers, to provide motorized wheelchair controls, and to allow a user to play a game via the BCI. When used in a cognitive assessment test, embodiments include the administration of unmodified standardized tests with results in the same or a similar format as those taken without a BCI. Various embodiments are disclosed to improve the accuracy of BCI test administration using a three-step process for each test question, which includes determining whether the user intends to select an answer, monitoring user brain activity to determine a selected answer, and verifying the selected answer. In addition, the selected answer may be verified by monitoring user brain activity in accordance with a hold-release process to determine whether a user intends to initiate a state change.
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公开(公告)号：US20240342695A1
公开(公告)日：2024-10-17
申请号：US18294641
申请日：2022-08-02
IPC分类号： B01J35/39 , B01J19/00 , B01J19/12 , B01J23/26 , B01J23/46 , B01J35/00 , B01J35/30 , B01J35/33 , B01J35/45 , B01J35/53 , B01J35/58 , B01J37/34
CPC分类号： B01J35/39 , B01J19/0013 , B01J19/127 , B01J23/26 , B01J23/464 , B01J35/19 , B01J35/33 , B01J35/397 , B01J35/398 , B01J35/45 , B01J35/53 , B01J35/58 , B01J37/345 , B01J2219/00144 , B01J2219/00155 , B01J2219/0892
摘要： A method of promoting a chemical reaction includes immersing a device in a solution contained in a reaction chamber, the device including a substrate and a plurality of conductive projections supported by the substrate, each conductive projection of the plurality of conductive projections having a semiconductor composition, irradiating the device to drive the chemical reaction, and controlling a temperature of the solution contained in the reaction chamber such that the temperature is maintained in a temperature range closer to a boiling temperature of the solution than a freezing temperature of the solution
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公开(公告)号：US20240341301A1
公开(公告)日：2024-10-17
申请号：US18627185
申请日：2024-04-04
发明人： Paul C. TANG , Y. Eugene Chen , Lenglam Lei
IPC分类号： A01N1/02
CPC分类号： A01N1/0226
摘要： Provided herein are pharmaceutical compositions and tissue/organ preservation solutions comprising itaconate and/or derivatives thereof and methods of use thereof. In particular, provided herein are compositions comprising itaconate and methods of use thereof for the preservation of tissues/organs for transplantation and treatment/prevention/reduction of conditions such as myocardial infarction, sudden cardiac arrest, stroke, senescence, cardiomyopathies, and cardiotoxicity.
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公开(公告)号：US20240336677A1
公开(公告)日：2024-10-10
申请号：US18579227
申请日：2022-07-14
发明人： Wenjing Wang , Xiaobo Mao , Yemima Rianik , Yuqing Liu , Ramhari Kumbhar
CPC分类号： C07K16/18 , A61K45/06 , A61K48/0033 , A61K48/0075 , A61P25/28 , C07K2317/569
摘要： Provided herein are compositions and methods to prevent and to treat α-synucleinopathies for research and therapeutic purposes. In particular, provided herein are compositions, methods, kits and uses for inhibition of pathological phosphorylation and spread of α-synuclein in the central nervous system as therapeutic targets of neurodegenerative disorders including dementia with Lewy bodies and Parkinson's disease dementia.
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公开(公告)号：US20240333757A1
公开(公告)日：2024-10-03
申请号：US18623296
申请日：2024-04-01
发明人： Kang G. SHIN , Mert D. Pese
IPC分类号： H04L9/40
CPC分类号： H04L63/1441 , H04L63/1416
摘要： A system for detecting and preventing, in real time, malicious broadcasting messages from an electronic control module attempting to attack a vehicle network is disclosed. The system includes electronic control modules in communication via a serial data link of the vehicle network. At least one electronic control module is configured to receive at least a portion of a serial message on the vehicle network transmitted by another electronic control module, identify the serial message as malicious based on the received portion of the serial message, and in response to identifying the serial message as malicious, inject a dominant bit into the serial message for the vehicle network to cause an error frame in the serial message. Other example systems and methods for detecting and preventing, in real time, malicious broadcasting messages are also disclosed.
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