公开(公告)号：US11813290B2

公开(公告)日：2023-11-14

申请号：US15024709

申请日：2014-09-09

申请人： ALESCO S.R.L.

发明人： Andrea Lacorte ,  Germano Tarantino ,  Gianni Lazzarini

IPC分类号： A61K33/42 ,  A23L33/16 ,  A61K33/26 ,  A61K45/06 ,  A61K33/18 ,  A61K33/06 ,  A61K9/20 ,  A61K9/14

CPC分类号： A61K33/42 ,  A23L33/16 ,  A61K9/145 ,  A61K9/2013 ,  A61K9/2018 ,  A61K33/06 ,  A61K33/18 ,  A61K33/26 ,  A61K45/06 ,  A23V2002/00 ,  A61K33/26 ,  A61K2300/00 ,  A61K33/42 ,  A61K2300/00 ,  A61K33/06 ,  A61K2300/00 ,  A61K33/18 ,  A61K2300/00 ,  A23V2002/00 ,  A23V2200/30 ,  A23V2250/1578 ,  A23V2250/1592 ,  A23V2250/1598 ,  A23V2250/161 ,  A23V2250/1642 ,  A23V2250/1842

摘要： The present invention relates to solid compositions, preferably in powder or granule form, based on minerals (semi-finished or raw material) and a process for preparing said solid compositions. Furthermore, the present invention relates to solid formulations (final products) and orally disintegrating formulations (final products) containing said solid compositions. Moreover, the present invention relates to a process for preparing said solid formulations and said orally disintegrating formulations. Finally, the present invention relates to the use of said solid compositions or said solid or orally disintegrating formulations in the treatment of disorders or diseases related to or derived from a deficiency of minerals such as magnesium (II), calcium (II), iron (III), zinc (II) and/or iodine. All the compositions or formulations of the present invention are suitable for pediatric subjects, adolescents, athletes, men, women, pregnant women and elderly.

公开(公告)号：US20180250326A1

公开(公告)日：2018-09-06

申请号：US15969829

申请日：2018-05-03

申请人： U.S. NUTRACEUTICALS, LLC d/b/a Valensa International

发明人： John A. Minatelli ,  W. Stephen Hill ,  Rudi E. Moerck

IPC分类号： A61K31/728 ,  A61K31/122 ,  A61K36/9066 ,  A61K45/06 ,  A61K31/202 ,  A61K31/685 ,  A61K31/7028 ,  A61K36/05 ,  A61K36/185 ,  A61K36/324 ,  A61K36/74 ,  A61K9/48 ,  A61K31/7008 ,  A61K9/00 ,  A61K35/60 ,  A23L33/115 ,  A23L33/12 ,  A23L33/10 ,  A61K35/32 ,  A61K33/22 ,  A61K31/726 ,  A61K38/39 ,  A61K35/612

CPC分类号： A61K31/728 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/4858 ,  A61K31/122 ,  A61K31/202 ,  A61K31/685 ,  A61K31/7008 ,  A61K31/7028 ,  A61K31/726 ,  A61K33/22 ,  A61K35/32 ,  A61K35/60 ,  A61K35/612 ,  A61K36/05 ,  A61K36/185 ,  A61K36/324 ,  A61K36/74 ,  A61K36/9066 ,  A61K38/39 ,  A61K45/06 ,  A61K2300/00 ,  A23V2200/316 ,  A23V2250/1842 ,  A23V2250/187 ,  A23V2250/1882

摘要： A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of joint pain. The composition includes pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments having a molecular weight of 0.5 to 300 kilodaltons (kDa) in an oral dosage form.

公开(公告)号：US20180235269A1

公开(公告)日：2018-08-23

申请号：US15960674

申请日：2018-04-24

申请人： Mead Johnson Nutrition Company

发明人： Dattatreya Banavara ,  John Alvey

IPC分类号： A23L33/115 ,  A23C9/14 ,  A23L33/135 ,  A23L33/00 ,  A23L33/19 ,  A23L33/12

CPC分类号： A23L33/115 ,  A23C9/14 ,  A23L33/12 ,  A23L33/135 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A23V2250/1578 ,  A23V2250/1588 ,  A23V2250/1592 ,  A23V2250/1598 ,  A23V2250/16 ,  A23V2250/161 ,  A23V2250/1612 ,  A23V2250/1614 ,  A23V2250/1618 ,  A23V2250/1642 ,  A23V2250/1842 ,  A23V2250/1866 ,  A23V2250/1868 ,  A23V2250/1876 ,  A23V2250/1882 ,  A23V2250/194 ,  A23V2250/28 ,  A23V2250/304 ,  A23V2250/54252 ,  A23V2250/612 ,  A23V2250/702 ,  A23V2250/7042 ,  A23V2250/7044 ,  A23V2250/7046 ,  A23V2250/7052 ,  A23V2250/7056 ,  A23V2250/706 ,  A23V2250/708 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714 ,  A23V2250/72

摘要： The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects.

公开(公告)号：US09962455B2

公开(公告)日：2018-05-08

申请号：US15698240

申请日：2017-09-07

申请人： Enzymotec Ltd.

发明人： Gai Ben Dror ,  Dorit Platt ,  Orly Farkash ,  Rassan Zuabi ,  Zohar Bar-On ,  Avidor Shulman ,  Dori Pelled ,  Yael Richter

IPC分类号： A61K31/201 ,  A61K31/202 ,  A61K47/54 ,  A23L33/00 ,  A23L33/12

CPC分类号： A61K47/544 ,  A21D2/32 ,  A23D7/013 ,  A23D9/013 ,  A23L33/12 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/201 ,  A61K31/202 ,  A61K31/66 ,  A61K31/685 ,  C07F9/10 ,  A23V2200/322 ,  A23V2250/1882 ,  A23V2250/1942 ,  A23V2250/1842

摘要： The invention described herein provides a preparation comprising a non-mammalian derived mixture of serine glycerophospholipid conjugates with a specific content and specific conjugation patterns of LA, linolenic acid (alpha-linolenic acid, gamma-linolenic acid) DHA and EPA which depend on utilizing different sources of lipids and uses of such preparations.

公开(公告)号：US20170231262A1

公开(公告)日：2017-08-17

申请号：US15584062

申请日：2017-05-02

申请人： Mead Johnson Nutrition Company

发明人： Dattatreya Banavara ,  John D. Alvey ,  Juan M. Gonzalez

IPC分类号： A23L33/00 ,  A23L33/17 ,  A23L33/16 ,  A23L33/10 ,  A23L33/12

CPC分类号： A23L33/40 ,  A23C2240/05 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23L33/16 ,  A23L33/17 ,  A23L33/19 ,  A23V2002/00 ,  A23V2250/1578 ,  A23V2250/1588 ,  A23V2250/1592 ,  A23V2250/1598 ,  A23V2250/16 ,  A23V2250/161 ,  A23V2250/1612 ,  A23V2250/1614 ,  A23V2250/1618 ,  A23V2250/1642 ,  A23V2250/1842 ,  A23V2250/1866 ,  A23V2250/1868 ,  A23V2250/1876 ,  A23V2250/1882 ,  A23V2250/194 ,  A23V2250/28 ,  A23V2250/304 ,  A23V2250/54252 ,  A23V2250/612 ,  A23V2250/702 ,  A23V2250/7042 ,  A23V2250/7044 ,  A23V2250/7046 ,  A23V2250/7052 ,  A23V2250/7056 ,  A23V2250/706 ,  A23V2250/708 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714 ,  A23V2250/72

摘要： The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects.

公开(公告)号：US20170223999A1

公开(公告)日：2017-08-10

申请号：US15405212

申请日：2017-01-12

申请人： NESTEC S.A.

发明人： Marie-Louise MATEUS ,  Tesfalidet HAILE ,  Pierre FOURRE

IPC分类号： A23L33/175 ,  A23L33/18 ,  A23L7/126 ,  A23L29/30 ,  A23L2/66 ,  A23L2/52

CPC分类号： A23L33/175 ,  A23L2/52 ,  A23L2/66 ,  A23L7/00 ,  A23L7/126 ,  A23L29/30 ,  A23L33/125 ,  A23L33/17 ,  A23L33/18 ,  A23V2002/00 ,  A23V2200/33 ,  A23V2250/1842 ,  A23V2250/0604 ,  A23V2250/54246 ,  A23V2250/54252 ,  A23V2250/5488 ,  A23V2250/6416 ,  A23V2250/628 ,  A23V2250/5106

摘要： The present disclosure provides products and methods that provide for the stability of functional amino acids in food matrices. In a general embodiment, the products include either a source of beta-glucans or a source of protein low in reducing sugars, in combination with a functional amino acid in a binder having low amounts of, or being substantially free of, reducing sugars. Methods for improving the stability of functional amino acids in food matrices are also provided. The products and methods of the present disclosure provide several advantages including, for example, the reduction or avoidance of degradation and browning of the products during processing and storage.

公开(公告)号：US09675635B2

公开(公告)日：2017-06-13

申请号：US14735370

申请日：2015-06-10

申请人： U.S. NUTRACEUTICALS, LLC

发明人： John A. Minatelli ,  W. Stephen Hill ,  Rudi E. Moerck

IPC分类号： A61K31/728 ,  A61K31/122 ,  A61K36/9066 ,  A61K45/06 ,  A61K31/202 ,  A61K31/685 ,  A61K31/7028 ,  A61K36/05 ,  A61K36/185 ,  A61K36/324 ,  A61K36/74 ,  A61K9/48 ,  A61K31/7008 ,  A61K35/60 ,  A23L33/115 ,  A23L33/12 ,  A23L33/10 ,  A61K9/00 ,  A61K31/726 ,  A61K33/22 ,  A61K35/32 ,  A61K38/39

CPC分类号： A61K31/728 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/4858 ,  A61K31/122 ,  A61K31/202 ,  A61K31/685 ,  A61K31/7008 ,  A61K31/7028 ,  A61K31/726 ,  A61K33/22 ,  A61K35/32 ,  A61K35/60 ,  A61K35/612 ,  A61K36/05 ,  A61K36/185 ,  A61K36/324 ,  A61K36/74 ,  A61K36/9066 ,  A61K38/39 ,  A61K45/06 ,  A61K2300/00 ,  A23V2200/316 ,  A23V2250/1842 ,  A23V2250/187 ,  A23V2250/1882

摘要： A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of joint pain. The composition includes pro-inflammatory low molecular weight microbial fermented sodium hyaluronate fragments and glucosamine in an oral dosage form.

公开(公告)号：US20170127712A1

公开(公告)日：2017-05-11

申请号：US15414877

申请日：2017-01-25

申请人： James John YIANNIOS

发明人： James John YIANNIOS

IPC分类号： A23L33/15

CPC分类号： A23G3/368 ,  A23G1/42 ,  A23G3/36 ,  A23G3/364 ,  A23G3/48 ,  A23G3/54 ,  A23L33/10 ,  A23L33/15 ,  A23V2002/00 ,  A23V2200/222 ,  A23V2250/1842 ,  A23V2250/31 ,  A23V2250/5086 ,  A23V2250/708 ,  A23V2250/712

摘要： A dietary supplement composition having a dispersion including a plurality of liposomal vesicles, includes an active ingredient, phospholipid contained in the liposomal vesicles, and a coating material. The active ingredient is incorporated within the liposomal vesicles having a barrier coating of the coating material including one of a biopolymer, polyethylene glycol, chitosan and a combination thereof. The coating material is free flowing in the dispersion such that the liposomal vesicles are surrounded by the coating material without being attached to the liposomal vesicles and without forming part of the liposomal vesicles and without affecting weight of the liposomal vesicles. The dispersion is filtered using a tangential flow technique, which washes out outer periphery of liposomal vesicles for removing inactive ingredients contained outside the liposomal vesicles without washing out the coating material surrounding the liposomal vesicles. The dietary supplement composition may be incorporated in gummies, chocolates, atomizers or powders.

公开(公告)号：US09585966B2

公开(公告)日：2017-03-07

申请号：US14871260

申请日：2015-09-30

申请人： Enzymotec Ltd.

发明人： Gai Ben Dror ,  Dorit Platt ,  Orly Farkash ,  Rassan Zuabi ,  Zohar Bar-On ,  Avidor Shulman ,  Dori Pelled ,  Yael Richter

IPC分类号： A61K31/66 ,  A61K31/685 ,  A61K47/48 ,  A23D9/013 ,  A23D7/01 ,  A21D2/32 ,  C07F9/10

CPC分类号： A61K47/544 ,  A21D2/32 ,  A23D7/013 ,  A23D9/013 ,  A23L33/12 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/201 ,  A61K31/202 ,  A61K31/66 ,  A61K31/685 ,  C07F9/10 ,  A23V2200/322 ,  A23V2250/1882 ,  A23V2250/1942 ,  A23V2250/1842

摘要： The invention described herein provides a preparation comprising a non-mammalian derived mixture of serine glycerophospholipid conjugates with a specific content and specific conjugation patterns of LA, linolenic acid (alpha-linolenic acid, gamma-linolenic acid) DHA and EPA which depend on utilizing different sources of lipids, and uses of such preparations.

摘要翻译： 本文描述的本发明提供包含非哺乳动物衍生的丝氨酸甘油磷脂缀合物的混合物的制剂，其具有LA，亚麻酸（α-亚麻酸，γ-亚麻酸）DHA和EPA的特定含量和特异性缀合图案，其依赖于使用不同的 脂质来源，以及这些制剂的用途。

公开(公告)号：US09585417B2

公开(公告)日：2017-03-07

申请号：US14132486

申请日：2013-12-18

申请人： ZEOLIFE INC.

发明人： James John Yiannios ,  Subhash Kekatpuray

IPC分类号： A23L33/10 ,  A23L1/305

CPC分类号： A23L33/10 ,  A23L33/15 ,  A23V2002/00 ,  A23V2200/222 ,  A23V2250/1842 ,  A23V2250/31 ,  A23V2250/5086 ,  A23V2250/708 ,  A23V2250/712

摘要： A method of making dietary supplement compositions includes generating an aqueous phase, generating an oil phase, performing a first homogenizing step by mixing the aqueous and oil phases, adding reduced glutathione to the aqueous-oil composition and performing a second homogenizing step by mixing the aqueous-oil composition and reduced glutathione, adding a first flavor to the aqueous-oil-glutathione composition, performing a third homogenizing step by mixing the aqueous-oil-glutathione composition and the first flavor, adding xanthan gum dispersed with glycerin to the aqueous-oil-glutathione-first-flavor composition and performing a fourth homogenizing step by mixing the aqueous-oil-glutathione-first-flavor composition and xanthan gum; adding a second flavor to the aqueous-oil-glutathione-first-flavor-xanthan composition and performing a fifth homogenizing step by mixing the aqueous-oil-glutathione-first-flavor-xanthan composition and the second flavor so as to form a dietary supplement composition. Such method provides a dietary supplement as a dispersion including active ingredients incorporated in liposomal vesicles having a barrier coating of polyethylene glycol.

摘要翻译： 制备膳食补充剂组合物的方法包括产生水相，产生油相，通过混合水相和油相进行第一均化步骤，将还原型谷胱甘肽加入到含水油组合物中，并通过混合水性 - 油组合物和还原型谷胱甘肽，向含水 - 谷物 - 谷胱甘肽组合物中添加第一风味，通过混合水 - 油 - 谷胱甘肽组合物和第一风味进行第三匀浆步骤，将分散有甘油的黄原胶加入含水油 - 谷胱甘肽 - 第一风味组合物，并通过混合水 - 油 - 谷胱甘肽 - 第一风味组合物和黄原胶进行第四匀浆步骤; 向含水 - 谷物 - 谷胱甘肽 - 第一香料 - 黄原胶组合物中加入第二种风味，并通过混合含水 - 谷物 - 谷胱甘肽 - 第一香味 - 黄原胶组合物和第二种风味进行第五均化步骤，以形成膳食补充剂 组成。 这种方法提供作为分散体的膳食补充剂，其包括并入脂质体囊泡中的活性成分，其具有聚乙二醇的阻隔涂层。