公开(公告)号：US12104008B2

公开(公告)日：2024-10-01

申请号：US16994220

申请日：2020-08-14

申请人： STEPAN COMPANY

发明人： Zhenhua Cui ,  Warren A. Kaplan ,  Sarah Wolek

IPC分类号： C08G59/06 ,  C08G18/42 ,  C08G18/48 ,  C08G59/14 ,  C08G63/06 ,  C08G65/331 ,  C08G65/34 ,  C08J9/00 ,  C09K5/14

CPC分类号： C08G59/063 ,  C08G18/4294 ,  C08G18/4895 ,  C08G59/14 ,  C08G63/06 ,  C08G65/331 ,  C08G65/34 ,  C08J9/0009 ,  C09K5/14 ,  C08G2110/0008 ,  C08G2110/0025 ,  C08G2115/02 ,  C08J2205/10 ,  C08J2375/06 ,  C08J2375/08 ,  Y02E60/14

摘要： Polyether- or polyester-epoxide polymer (PEEP) compositions are disclosed. The compositions comprise reaction products of a polyepoxide compound and a polyol composition. The polyol composition has a melting point within the range of 20° C. to 100° C. and a hydroxyl number less than 35 mg KOH/g. The PEEP composition is a solid-solid phase-change material. As measured by differential scanning calorimetry (DSC) at a heating/cooling rate of 10° C./minute, the PEEP composition has a transition temperature within the range of −10° C. to 70° C., a latent heat at the transition temperature within the range of 30 to 200 J/g, and little or no detectable hysteresis or supercooling upon thermal cycling over at least five heating/cooling cycles that encompass the transition temperature. The PEEP compositions should enable formulators to manage thermal energy changes in many practical applications, including automotive, marine or aircraft parts, building materials, appliance insulation, electronics, textiles, garments, and paints or coatings.

公开(公告)号：US20240059903A1

公开(公告)日：2024-02-22

申请号：US18268807

申请日：2022-02-28

申请人： SUN CHEMICAL CORPORATION

发明人： Jürgen DIEKER ,  Florian MAESING

IPC分类号： C09D4/00 ,  C08F220/30 ,  C08F222/10 ,  C08G65/331 ,  C09D133/14 ,  C09D135/02 ,  C09D11/107 ,  C09D11/101 ,  C09D11/38 ,  B65D65/42

CPC分类号： C09D4/00 ,  C08F220/302 ,  C08F222/1063 ,  C08F222/103 ,  C08G65/331 ,  C09D133/14 ,  C09D135/02 ,  C09D11/107 ,  C09D11/101 ,  C09D11/38 ,  B65D65/42

摘要： The present invention relates to a new class of photoinitiator compositions, which are especially suited for use in low migration packaging materials. The present invention also relates to inks, coatings, varnishes and adhesives made therefrom.

公开(公告)号：US11834553B2

公开(公告)日：2023-12-05

申请号：US17062457

申请日：2020-10-02

申请人： Nektar Therapeutics

发明人： Antoni Kozlowski ,  Samuel P. McManus ,  Sachin Tipnis ,  Greg Lavaty ,  David Swallow ,  John R. Handley ,  Anthony G. Schaefer

IPC分类号： C08G65/331 ,  C08G65/329 ,  C08G65/333 ,  A61K47/60 ,  C08G65/48 ,  C07D491/22 ,  C07C51/41 ,  C07C53/18 ,  A61K31/4745

CPC分类号： C08G65/331 ,  A61K31/4745 ,  A61K47/60 ,  C07C51/412 ,  C07C53/18 ,  C07D491/22 ,  C08G65/329 ,  C08G65/33396 ,  C08G65/48 ,  C08L2203/02

摘要： Among other aspects, provided herein is a mixed-acid salt of a water-soluble polymer-drug conjugate, along with related methods of making and using the same. The mixed-salt acid salt is stably formed, and appears to be more resistant to hydrolytic degradation than the corresponding predominantly pure acid salt or free base forms of the polymer-drug conjugate. The mixed acid salt is reproducibly prepared and recovered, and provides surprising advantages over non-mixed acid salt forms of the water-soluble polymer drug conjugate.

公开(公告)号：US11649397B1

公开(公告)日：2023-05-16

申请号：US17875203

申请日：2022-07-27

申请人： Saudi Arabian Oil Company

发明人： Shaohua Chen ,  Ming Han ,  Abdulkareem AlSofi

IPC分类号： C09K8/588 ,  C08G65/331 ,  C08L33/26 ,  C08L71/02 ,  C08F220/56

CPC分类号： C09K8/588 ,  C08F220/56 ,  C08G65/3315 ,  C08L33/26 ,  C08L71/02

摘要： This disclosure relates to water-soluble viscosity reducer complexes for use in reducing the viscosity of heavy oil in oil recovery operations. The viscosity reducer complexes contain a hydrophilic component of polyaromatic-hydrocarbon-based polymers and a hydrophilic component of cyclodextrin-based polymers.

公开(公告)号：US11634540B2

公开(公告)日：2023-04-25

申请号：US17538885

申请日：2021-11-30

申请人： Nektar Therapeutics

发明人： Sean M. Culbertson ,  Xiaoming Shen ,  Antoni Kozlowski ,  Samuel P. McManus

IPC分类号： A61K47/60 ,  C08G65/26 ,  C08L71/02 ,  C07K1/00 ,  C07K17/08 ,  C08G65/331 ,  C08G65/333 ,  C08G65/332 ,  A61K38/00

摘要： Provided herein are polymeric α-hydroxy aldehyde or α-hydroxy ketone reagents which can be conjugated to amine-containing compounds to form stable conjugates in a single-step reaction. In selected embodiments, the polymeric reagent itself incorporates an internal proton-abstracting (basic) functional group, to promote more efficient reaction. The substituent is appropriately situated, via a linker if necessary, to position the group for proton abstraction, preferably providing a 4- or 5-bond spacing between the abstracting atom and the hydrogen atom on the α-carbon. Also provided are methods of using the reagents and stable, solubilized conjugates of the reagents with biologically active compounds. In preferred embodiments, the polymeric component of the reagent or conjugate is a polyethylene glycol.

公开(公告)号：US20230090239A1

公开(公告)日：2023-03-23

申请号：US17788075

申请日：2020-12-22

申请人： SHOWA DENKO K.K.

发明人： Masaki NANKO

IPC分类号： C08G65/00 ,  C08G65/331 ,  C08G65/333 ,  C10M107/38 ,  G11B5/725

摘要： The present invention provides a fluorine-containing ether compound represented by the following formula: R1—R2—CH2—R3—CH2—R4—R5 (in the formula, R3 represents a perfluoropolyether chain; R1 and R5 each independently represent any of an alkyl group which may have a substituent, an organic group having a double bond or a triple bond, and a hydrogen atom; —R2—CH2—R3 is represented by -[A]-[B]—O—CH2—R3; R3—CH2—R4— is represented by R3—CH2—O—[C]-[D]-; [A] is represented by Formula (4), [B] is represented by Formula (5), [C] is represented by Formula (6), and [D] is represented by Formula (7)):

公开(公告)号：US11530295B2

公开(公告)日：2022-12-20

申请号：US16887081

申请日：2020-05-29

申请人： NOF CORPORATION

发明人： Takuma Tsubusaki ,  Yuji Yamamoto

IPC分类号： A61K47/60 ,  C08G65/333 ,  C07D405/06 ,  C08G65/329 ,  C07D317/22 ,  C07D317/28 ,  C08G65/331 ,  C08G65/337 ,  C08G65/334 ,  C07D317/20 ,  C07D317/24

摘要： A hydrophilic polymer derivative having a cyclic benzylidene acetal linker represented by the following formula (1): wherein R1 and R6 are each independently a hydrogen atom or a hydrocarbon group; R2, R3, R4 and R5 are each independently an electron-withdrawing or electron-donating substituent or a hydrogen atom; X1 is a chemically reactive functional group; P is a hydrophilic polymer; s is 1 or 2, t is 0 or 1, and s+t is 1 or 2; w is an integer of 1 to 8; and Z1 and Z2 are each independently a selected divalent spacer.

公开(公告)号：US11427680B2

公开(公告)日：2022-08-30

申请号：US16469636

申请日：2017-12-12

申请人： SOLVAY SPECIALTY POLYMERS ITALY S.P.A.

发明人： Cristiano Monzani ,  Vito Tortelli ,  Marco Galimberti ,  Roberto Valsecchi ,  Patrizia Maccone

IPC分类号： C08G65/00 ,  C08G65/323 ,  C08G65/331 ,  G11B5/71 ,  C10M107/38

摘要： The present invention relates to a novel process for the synthesis of (per)fluoropolyether polymers, to certain novel (per)fluoropolyether polymers. The present invention also relates to the use of the (per)fluoropolyether polymers thus obtained as intermediate compounds for the manufacture of further polymers suitable for use as lubricants, notably for magnetic recording media (MRM).

公开(公告)号：US20220118100A1

公开(公告)日：2022-04-21

申请号：US17561342

申请日：2021-12-23

申请人： Xiamen Sinopeg Biotech Co., Ltd.

发明人： WenGui WENG ,  Chao LIU ,  JinCheng LIAO ,  JinChun YUAN

IPC分类号： A61K47/60 ,  C08G65/08 ,  C08G65/331 ,  C08G65/26

摘要： The monofunctional branched poly(ethylene glycol) (PEG) has a general formula shown in formula (1), and the bio-related substance modified by the monofunctional branched PEG has a general formula shown in formula (2), wherein X1 and X2 are each independently a hydrocarbon group having 1 to 20 carbon atoms, n1 and n2 are each independently an integer selected from 1 to 1000, n3 is an integer selected from 11 to 1000, L1, L2 are each independently a linking group, p is 0 or 1, q is 0 or 1, R1 is a hydrogen atom or a hydrocarbon group having 1 to 20 carbon atoms, D is a bio-related substance, Z is a linking group, and Z can react with the bio-related substance to form a residue group L3. The PEG-modified bio-related substance maintains good biological activity, and has better solubility and a longer half-life in vivo.

公开(公告)号：US11220649B2

公开(公告)日：2022-01-11

申请号：US16480464

申请日：2017-12-04

申请人： SHOWA DENKO K.K.

发明人： Naoya Fukumoto ,  Daisuke Yagyu ,  Yuta Yamaguchi ,  Shoko Uetake ,  Tsuyoshi Kato ,  Hiroyuki Tomita ,  Ryuuta Miyasaka ,  Katsumi Murofushi

IPC分类号： C10M105/54 ,  C07C43/178 ,  G11B5/725 ,  C08G65/331 ,  C10M107/38 ,  C10N20/04 ,  C10N30/06 ,  C10N50/00 ,  C10N40/18

摘要： A fluorine-containing ether compound represented by Formula (1) is provided; R1—R2—CH2—R3—CH2—R4—R5  (1) (In Formula (1), R1 and R5 may be the same as or different from each other and each represents an alkenyl group having 2 to 8 carbon atoms or an alkynyl group having 3 to 8 carbon atoms, R2 and R4 may be the same as or different from each other and each represents a divalent linking group having a polar group, and R3 represents a perfluoropolyether chain, with a proviso that R1 and R2 are, and R4 and R5 are divided due to the presence of an atom other than the carbon atom such as an oxygen atom).