Electrode devices for nerve stimulation and cardiac sensing
    93.
    发明授权
    Electrode devices for nerve stimulation and cardiac sensing 有权
    用于神经刺激和心脏感知的电极装置

    公开(公告)号:US08615294B2

    公开(公告)日:2013-12-24

    申请号:US12228630

    申请日:2008-08-13

    IPC分类号: A61N1/00

    摘要: Apparatus is provided for application to a nerve of a subject, the apparatus comprising an electrode device, which comprises a housing, which is configured to be placed at least partially around the nerve, so as to define an outer surface of the electrode device and an inner surface that faces the nerve. The electrode device further comprises one or more first electrode contact surfaces, fixed to the inner surface of the housing, and one or more second electrode contact surfaces, fixed to the outer surface of the housing. Other embodiments are also described.

    摘要翻译: 提供了用于对受试者的神经施用的装置,该装置包括电极装置,该电极装置包括壳体,该壳体构造成至少部分地围绕神经放置,以限定电极装置的外表面,以及 面向神经的内表面。 电极装置还包括固定到壳体的内表面的一个或多个第一电极接触表面和固定到外壳的外表面的一个或多个第二电极接触表面。 还描述了其它实施例。

    Handling commands within a write-once read-many storage device configuration
    94.
    发明授权
    Handling commands within a write-once read-many storage device configuration 有权
    在一次写入多次存储设备配置中处理命令

    公开(公告)号:US08595426B2

    公开(公告)日:2013-11-26

    申请号:US13084111

    申请日:2011-04-11

    摘要: In a particular embodiment, a storage device with a memory, a controller, and a host interface has a write-once read-many device configuration. The memory contains a database having entries, each entry for a logical memory address. The memory further contains information for converting each logical memory address to a redirected logical memory address that corresponds to a physical memory location. The controller receives a command specifying a logical memory address and interprets the command based on information extracted from the database. The controller executes the command according to the information.

    摘要翻译: 在特定实施例中,具有存储器,控制器和主机接口的存储设备具有一次写入许可的设备配置。 内存包含一个具有条目的数据库,每个条目用于逻辑内存地址。 存储器还包含用于将每个逻辑存储器地址转换为对应于物理存储器位置的重定向逻辑存储器地址的信息。 控制器接收指定逻辑存储器地址的命令,并根据从数据库提取的信息解释命令。 控制器根据信息执行命令。

    Techniques for nerve stimulation
    95.
    发明授权
    Techniques for nerve stimulation 有权
    神经刺激技术

    公开(公告)号:US08326438B2

    公开(公告)日:2012-12-04

    申请号:US12589132

    申请日:2009-10-19

    申请人: Shai Ayal Ehud Cohen

    发明人: Shai Ayal Ehud Cohen

    IPC分类号: A61N1/04

    摘要: Apparatus is provided for applying current to a nerve, including a housing, adapted to be placed in a vicinity of the nerve, and at least one cathode and at least one anode, fixed to the housing. The apparatus further includes two or more passive electrodes, fixed to the housing, and a conducting element, which electrically couples the passive electrodes to one another. Other embodiments are also described.

    摘要翻译: 提供了用于向包括适于放置在神经附近的包括壳体的神经施加电流的装置,以及固定到壳体的至少一个阴极和至少一个阳极。 该装置还包括固定到壳体的两个或多个无源电极和将无源电极彼此电耦合的导电元件。 还描述了其它实施例。

    PARASYMPATHETIC NERVE STIMULATION
    96.
    发明申请
    PARASYMPATHETIC NERVE STIMULATION 审中-公开
    PARASYMPATHETIC NERVE刺激

    公开(公告)号:US20120303080A1

    公开(公告)日:2012-11-29

    申请号:US13493499

    申请日:2012-06-11

    IPC分类号: A61N1/365 A61N1/05

    摘要: A method is provided, including identifying that a subject is at risk of suffering from atrial fibrillation (AF). Responsively to the identifying, a risk of an occurrence of an episode of the AF is reduced by coupling an electrode device to a site of a subject containing parasympathetic nervous tissue; driving, by a control unit, the electrode device to apply an electrical current to the site not responsively to any physiological parameters sensed by any device directly or indirectly coupled to the control unit; and configuring the current to stimulate autonomic nervous tissue in the site. Other embodiments are also described.

    摘要翻译: 提供了一种方法,包括确定受试者处于心房颤动(AF)的风险。 响应于鉴定,通过将电极装置耦合到包含副交感神经组织的受试者的部位来降低发生AF发作的风险; 通过控制单元驱动电极装置,以不响应于直接或间接地耦合到控制单元的任何装置感测到的任何生理参数来施加电流到现场; 并配置电流以刺激现场的自主神经组织。 还描述了其它实施例。

    Intermittent electrical stimulation
    97.
    发明授权
    Intermittent electrical stimulation 有权
    间歇性电刺激

    公开(公告)号:US08224444B2

    公开(公告)日:2012-07-17

    申请号:US11975654

    申请日:2007-10-19

    IPC分类号: A61N1/00

    CPC分类号: A61N1/36114

    摘要: Apparatus is provided including an electrode device, adapted to be coupled to a site of a subject; and a control unit, adapted to drive the electrode device to apply a current to the site intermittently during alternating “on” and “off” periods, each of the “on” periods having an “on” duration equal to between 1 and 10 seconds, and each of the “off” periods having an “off” duration equal to at least 50% of the “on” duration. Other embodiments are also described.

    摘要翻译: 提供了包括电极装置的装置,其适于联接到受试者的部位; 以及控制单元,其适于在交替的“接通”和“关闭”周期期间驱动电极装置间歇地施加电流到场地,每个“接通”周期具有等于1至10秒的“接通”持续时间 ,并且每个“关闭”周期具有等于“开启”持续时间的至少50%的“关闭”持续时间。 还描述了其它实施例。

    Techniques for prevention of atrial fibrillation
    98.
    发明授权
    Techniques for prevention of atrial fibrillation 有权
    预防心房颤动的技术

    公开(公告)号:US08204591B2

    公开(公告)日:2012-06-19

    申请号:US11657784

    申请日:2007-01-24

    IPC分类号: A61N1/36

    摘要: A method is provided, including identifying that a subject is at risk of suffering from atrial fibrillation (AF). Responsively to the identifying, a risk of an occurrence of an episode of the AF is reduced by applying an electrical current to a site of the subject selected from the group consisting of: a vagus nerve, a sinoatrial (SA) node fat pad, a pulmonary vein, a carotid artery, a carotid sinus, a coronary sinus, a vena cava vein, a jugular vein, an azygos vein, an innominate vein, and a subclavian vein, and configuring the current to stimulate autonomic nervous tissue in the site. Other embodiments are also described.

    摘要翻译: 提供了一种方法,包括识别受试者处于心房颤动(AF)的风险。 响应于识别,通过向选自以下的组中的受试者的位点施加电流来减少AF的发作的风险:迷走神经,窦房(SA)节点脂肪垫, 肺静脉,颈动脉,颈动脉窦,冠状窦,腔静脉,颈静脉,纯合静脉,无名静脉和锁骨下静脉,并配置电流以刺激部位的自主神经组织。 还描述了其它实施例。

    TECHNIQUES FOR REDUCING PAIN ASSOCIATED WITH NERVE STIMULATION
    99.
    发明申请
    TECHNIQUES FOR REDUCING PAIN ASSOCIATED WITH NERVE STIMULATION 有权
    减少与神经刺激相关的疼痛的技术

    公开(公告)号:US20110137365A1

    公开(公告)日:2011-06-09

    申请号:US13022199

    申请日:2011-02-07

    CPC分类号: A61N1/36071 A61N1/36114

    摘要: Apparatus is provided including an electrode device and a control unit. The electrode device is configured to be coupled to a site of a subject selected from the group consisting of: a vagus nerve, an epicardial fat pad, a pulmonary vein, a carotid artery, a carotid sinus, a coronary sinus, a vena cava vein, a right ventricle, a right atrium, and a jugular vein. The control unit is configured to drive the electrode device to apply to the site a current in at least first and second bursts, the first burst including a plurality of pulses, and the second burst including at least one pulse, and set (a) a pulse repetition interval (PRI) of the first burst to be on average at least 20 ms, (b) an interburst interval between initiation of the first burst and initiation of the second burst to be less than 10 seconds, (c) an interburst gap between a conclusion of the first burst and the initiation of the second burst to have a duration greater than the average PRI, and (d) a burst duration of the first burst to be less than a percentage of the interburst interval between, the percentage being less than 67%. Other embodiments are also described.

    摘要翻译: 提供了包括电极装置和控制单元的装置。 电极装置被配置为耦合到选自以下的对象的部位:迷走神经,心外膜脂肪垫,肺静脉,颈动脉,颈动脉窦,冠状窦,腔静脉 ,右心室,右心房和颈静脉。 所述控制单元被配置为驱动所述电极装置以至少第一和第二脉冲串向所述现场应用电流,所述第一脉冲串包括多个脉冲,所述第二脉冲串包括至少一个脉冲,并且设置(a) 脉冲重复间隔(PRI)平均至少为20ms,(b)第一脉冲串的起始与第二脉冲串的起始之间的间歇间隔小于10秒,(c)突发间隙 在第一突发的结论和第二突发的开始之间具有大于平均PRI的持续时间,以及(d)第一突发的突发持续时间小于突发间间隔的百分比,百分比为 小于67%。 还描述了其它实施例。

    ELECTRODE CUFFS
    100.
    发明申请
    ELECTRODE CUFFS 有权
    电极铜

    公开(公告)号:US20110098796A1

    公开(公告)日:2011-04-28

    申请号:US12947608

    申请日:2010-11-16

    IPC分类号: A61N1/05

    CPC分类号: A61N1/0556 A61N1/36114

    摘要: Apparatus is provided for application to a nerve of a subject, including an electrode cuff, which includes a housing, which is configured to be placed at least partially around the nerve so as to define an inner surface of the housing that faces the nerve. A plurality of insulating elements are coupled to the inner surface of the housing at respective insulating element longitudinal positions along the housing, such that the inner surface of the housing and pairs of the insulating elements define one or more respective cavities at respective cavity longitudinal positions along the housing. One or more electrodes are fixed to the housing in fewer than all of the cavities, such that at least one of the cavities is an empty cavity that does not have an electrode positioned therein. Other embodiments are also described.

    摘要翻译: 提供了用于施用于受试者神经的装置,包括电极箍,其包括壳体,其被构造成至少部分地围绕神经放置,以限定外壳面向神经的内表面。 多个绝缘元件在沿着壳体的相应绝缘元件纵向位置处联接到壳体的内表面,使得壳体的内表面和成对的绝缘元件在相应的腔纵向位置处限定一个或多个相应的腔 住房。 一个或多个电极在少于所有的空腔中固定到壳体,使得至少一个空腔是不具有位于其中的电极的空腔。 还描述了其它实施例。