公开(公告)号：US06226757B1

公开(公告)日：2001-05-01

申请号：US09169245

申请日：1998-10-09

申请人： Frederick A. Ware ,  Richard M. Barth ,  Donald C. Stark ,  Craig E. Hampel ,  Ely K. Tsern ,  Abhijit M. Abhyankar ,  Thomas J. Holman ,  Andrew V. Anderson ,  Peter D. MacWilliams

发明人： Frederick A. Ware ,  Richard M. Barth ,  Donald C. Stark ,  Craig E. Hampel ,  Ely K. Tsern ,  Abhijit M. Abhyankar ,  Thomas J. Holman ,  Andrew V. Anderson ,  Peter D. MacWilliams

IPC分类号： G06F104

CPC分类号： G06F13/4226

摘要： A digital system includes a clock line carrying a clock signal and a communication bus with a signal time of flight longer than a cycle of the clock signal. A master device is connected to the communication bus and the clock line. The master device selectively applies signals to the communication bus. A set of slave devices are connected to the communication bus and the clock line. Each slave device of the set of slave devices has an associated latency delay arising from its position on the communication bus. Each slave device includes delay circuitry to compensate for the associated latency delay such that the master device observes a uniform minimum latency for each slave device in response to applying signals to the communication bus.

摘要翻译： 一个数字系统包括一个带有时钟信号的时钟线和一个具有比时钟信号周期长的信号时间的通信总线。 主设备连接到通信总线和时钟线。 主设备选择性地向通信总线施加信号。 一组从设备连接到通信总线和时钟线。 一组从设备的每个从设备具有由其在通信总线上的位置产生的相关联的延迟延迟。 每个从设备包括延迟电路以补偿相关联的延迟延迟，使得主设备响应于向通信总线应用信号而观察到每个从设备的均匀最小等待时间。

公开(公告)号：US06219817B1

公开(公告)日：2001-04-17

申请号：US09063337

申请日：1998-04-20

申请人： Thomas J. Holman

发明人： Thomas J. Holman

IPC分类号： H03M1300

CPC分类号： G06F11/1044 ,  G06F11/10

摘要： Error correction and detection for time-multiplexed binary 72-tuples over 18 wires to detect a wire fault. A syndrome is computed using a parity check matrix, where circuits for realizing the parity check matrix multiplication can be realized with only two levels of XOR gates and in which the computation is pipelined to process the time-multiplexed binary 72-tuple.

摘要翻译： 时间多路复用二进制72元组18路以上的纠错和检测，以检测线路故障。 使用奇偶校验矩阵计算校正子，其中用于实现奇偶校验矩阵乘法的电路可以仅用两级XOR门来实现，并且其中计算被流水线处理时间复用二进制72元组。

公开(公告)号：US6152944A

公开(公告)日：2000-11-28

申请号：US34434

申请日：1998-03-04

申请人： Thomas J. Holman ,  Louis G. Ellis ,  Gregory K. Olson ,  Linda R. Lorentzen Cornelius ,  Richard J. Traxler ,  Scott M. Hanson ,  Tracee E. J. Eidenschink ,  Sonja J. K. Williams

发明人： Thomas J. Holman ,  Louis G. Ellis ,  Gregory K. Olson ,  Linda R. Lorentzen Cornelius ,  Richard J. Traxler ,  Scott M. Hanson ,  Tracee E. J. Eidenschink ,  Sonja J. K. Williams

IPC分类号： A61M25/00 ,  A61F2/82 ,  A61F2/84 ,  A61M29/02 ,  A61M29/00

CPC分类号： A61M25/104 ,  A61F2/0095 ,  A61F2/958 ,  A61F2002/9583 ,  A61M2025/1081

摘要： A balloon catheter is provided having an expandable distal portion and balloon protector means comprising a first removable sleeve having a variable inner diameter to ease sliding the first sleeve over the balloon, and an optional second removable (outer) sleeve positioned over the inner sleeve, the second (outer) sleeve having a constrictive relationship with the first (inner) sleeve, said first and second sleeves being removed prior to use of the catheter. A stent delivery system is provided to facilitate introduction and placement of a stent, and includes a catheter having an expandable distal portion constructed and arranged for expanding the outer diameter of the catheter from a contracted state to an expanded state, said distal portion further comprising a balloon and at least one dam over which the balloon extends, and a stent positioned around the distal portion of the catheter around the balloon or gripper linear control device, said stent having a contracted condition, being sized in the contracted condition to closely surround the balloon in the contracted state, and being expandable to an expanded condition; a first removable (inner) sleeve in the region of the distal portion of the catheter positioned around the stent (and between the dams where the device comprises two dams), said first sleeve comprising a first end, a second end and a variable inner diameter to ease sliding the sleeve over the balloon and stent; an optional second removable (outer) sleeve positioned over the stent, first sleeve and at least one dam, said second (outer) sleeve having a constrictive relationship with the first (inner) sleeve, whereby when compressed by the outer sleeve, the inner sleeve will have an inner diameter approximately equal to or less than the outer profile of the collapsed balloon over the at least one dam, said first and second sleeves being removed prior to use of the stent delivery system and release of the stent by expansion of the balloon.

公开(公告)号：US6101614A

公开(公告)日：2000-08-08

申请号：US955023

申请日：1997-10-21

申请人： Mark A. Gonzales ,  Thomas J. Holman ,  Patrick F. Stolt

发明人： Mark A. Gonzales ,  Thomas J. Holman ,  Patrick F. Stolt

IPC分类号： G06F11/10 ,  G06F11/08

CPC分类号： G06F11/106 ,  G06F11/1056

摘要： The present invention provides a method and apparatus for automatically scrubbing ECC errors in memory upon the detection of a correctable error in data read from memory. This is performed by providing in a memory controller memory control logic for controlling accesses to memory, an ECC error checking and correcting unit for checking data read from memory for errors and correcting any correctable errors found in the read data, a first data buffer for storing the corrected read data output from the ECC error checking and correcting unit and a writeback path having an input end coupled to an output of the first data buffer and an output end coupled to memory. Upon the detection of a correctable error in data read from a particular memory location, the ECC error checking and correcting unit signals to the memory control logic the existence of a correctable error in the read data. The memory control logic then obtains exclusive control over the first data buffer and the writeback path to control writing of the corrected read data onto the writeback path and subsequently to memory.

摘要翻译： 本发明提供一种用于在检测到从存储器读取的数据中的可校正误差时自动擦除存储器中的ECC错误的方法和装置。 这通过在内存控制器中提供用于控制对存储器的访问的存储器控​​制逻辑，用于检查从存储器读取的数据的ECC错误检查和校正单元，并且校正在读取的数据中发现的任何可校正的错误，第一数据缓冲器，用于存储 从ECC错误检查和校正单元输出的经校正的读取数据和具有耦合到第一数据缓冲器的输出的输入端的写回路径和耦合到存储器的输出端。 在检测到从特定存储器位置读取的数据中的可校正错误时，ECC错误检查和校正单元向存储器控制逻辑信号发送读取数据中存在可校正错误。 存储器控制逻辑然后获得对第一数据缓冲器和写回路径的排他控制，以控制将校正后的读取数据写入写回路径并随后到存储器。

公开(公告)号：US5721860A

公开(公告)日：1998-02-24

申请号：US767853

申请日：1996-12-17

申请人： Patrick F. Stolt ,  Thomas J. Holman

发明人： Patrick F. Stolt ,  Thomas J. Holman

IPC分类号： G06F12/00 ,  G06F13/00 ,  G06F13/16

CPC分类号： G06F13/1694 ,  Y02B60/1228

摘要： The present invention provides a method and apparatus in a memory controller coupled between a system bus and memory for independently supporting one of a Synchronous DRAM (SDRAM) and an Asynchronous DRAM (ADRAM) memory type via common signal pins. According to the preferred embodiment, the memory controller comprises memory control logic for generating both SDRAM and ADRAM memory interface signals and multiplexing means for selecting as output onto common signal pins either set of interface signals depending upon a memory type setting programmed within a configuration register. The memory control logic comprises at least a request processor in addition to two memory state machines, one for SDRAM and the other for ADRAM memory operations. When a system bus request is received by the request processor, it is assigned to a request state machine which interacts with both the SDRAM state machine and the ADRAM state machine to generate two sets of memory interface signals in addition to two sets of internal control signals. The sets of signals are input to a multiplexor provided for each type of control signals (i.e., memory interface and internal control), which multiplexors are controlled by the memory type select signal output from the configuration register. Based on the memory type setting programmed into the configuration registers, the appropriate sets of memory interface and internal control signals (i.e., either SDRAM or ADRAM) are selected for output to the memory array and to other units of the memory controller, respectively.

摘要翻译： 本发明提供一种耦合在系统总线和存储器之间的存储器控​​制器中的方法和装置，用于通过公共信号引脚独立地支持同步DRAM（SDRAM）和异步DRAM（ADRAM）存储器类型之一。 根据优选实施例，存储器控制器包括用于产生SDRAM和ADRAM存储器接口信号的存储器控​​制逻辑和用于根据在配置寄存器内编程的存储器类型设置，将共同信号引脚选择为接口信号的集合的多路复用装置。 除了两个存储器状态机之外，存储器控制逻辑至少包括一个请求处理器，一个用于SDRAM，另一个用于ADRAM存储器操作。 当请求处理器接收到系统总线请求时，它被分配给请求状态机，该请求状态机与SDRAM状态机和ADRAM状态机进行交互，以产生两组存储器接口信号，以及两组内部控制信号 。 这些信号组被输入到为每种类型的控制信号（即，存储器接口和内部控制）提供的多路复用器，该多路复用器由从配置寄存器输出的存储器类型选择信号控制。 基于编程到配置寄存器中的存储器类型设置，选择适当的存储器接口组和内部控制信号（即，SDRAM或ADRAM）以输出到存储器阵列和存储器控制器的其他单元。

公开(公告)号：US5554119A

公开(公告)日：1996-09-10

申请号：US187614

申请日：1994-01-27

申请人： Kent D. Harrison ,  Gary L. Hendrickson ,  Thomas J. Holman ,  Daniel M. Lafontaine ,  Matthew J. Miller ,  David B. Robinson

发明人： Kent D. Harrison ,  Gary L. Hendrickson ,  Thomas J. Holman ,  Daniel M. Lafontaine ,  Matthew J. Miller ,  David B. Robinson

IPC分类号： A61M25/00 ,  A61F2/958 ,  A61M16/04 ,  A61M29/02 ,  A61M5/32

CPC分类号： A61M25/1002 ,  A61M16/0481 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2025/1072 ,  A61M2025/1097

摘要： A drug delivery catheter which may be inserted into a vessel, such as a blood vessel is disclosed. The drug delivery catheter comprises any elongated tubular member which has a proximal end and a distal end. A drug lumen which provides a communication path for fluid is provided in the elongated tubular member for delivering a fluid, such as the drug to be administered. An inflatable balloon assembly is provided at the distal end of the elongated tubular member. The balloon assembly includes apertures which communicate with the drug lumen. The balloon assembly comprises a tubular balloon which is helically wound through the elongated tubular member and a sheath. The sheath is attached to the helically wound tubular balloon such that when the balloon member is uninflated, the first fluid in the vessel flows around the balloon assembly and such that when the balloon member is inflated, sections of the helically wound balloon contact the vessel wall to form a containment pocket between the vessel wall, the contacting sections of the balloon and the sheath. The apertures are provided in the containment pocket. An inflatable lumen is defined through the interior of the helically wound balloon and the sheath to allow perfusion of the first fluid.

摘要翻译： 公开了一种可插入容器（如血管）中的药物输送导管。 药物递送导管包括具有近端和远端的任何细长管状构件。 提供用于流体的连通路径的药物腔室设置在细长管状构件中，用于输送流体，例如待施用的药物。 在细长管状构件的远端处设置可充气气囊组件。 气囊组件包括与药物腔连通的孔。 球囊组件包括通过细长管状构件和护套螺旋缠绕的管状球囊。 护套附接到螺旋形缠绕的管状气囊，使得当球囊构件未膨胀时，容器中的第一流体围绕球囊组件流动，使得当球囊构件膨胀时，螺旋形卷绕的球囊的部分接触血管壁 以在容器壁，球囊和护套的接触部分之间形成容纳袋。 孔口设置在容纳口袋中。 通过螺旋缠绕气囊和护套的内部限定可充气腔，以允许第一流体的灌注。

公开(公告)号：US5425718A

公开(公告)日：1995-06-20

申请号：US141149

申请日：1993-10-22

申请人： Sew-Wah Tay ,  Thomas J. Holman

发明人： Sew-Wah Tay ,  Thomas J. Holman

IPC分类号： A61M25/06 ,  A61M5/158

CPC分类号： A61M25/0643

摘要： The needle assembly of the present invention includes a rigid cannula with a blunt distal end, a needle housed inside the cannula, a hub on the needle for controlling the position of the distal end of the needle with respect to the distal end of the cannula and a stop connected to the cannula for limiting the distance of travel of the distal end of the needle. The preferred embodiment may also include a spring attached to the needle hub. The present invention also encompasses methods of using the needle assembly.

摘要翻译： 本发明的针组件包括具有钝的远端的刚性插管，容纳在插管内的针，针上的毂，用于控制针的远端相对于插管的远端的位置;以及 连接到插管的止动件用于限制针的远端的行进距离。 优选实施例还可以包括附接到针座的弹簧。 本发明还包括使用针组件的方法。

公开(公告)号：US5407424A

公开(公告)日：1995-04-18

申请号：US22048

申请日：1993-02-24

申请人： Daniel M. LaFontaine ,  Thomas J. Holman ,  Daniel O. Adams

发明人： Daniel M. LaFontaine ,  Thomas J. Holman ,  Daniel O. Adams

IPC分类号： A61M1/00 ,  A61M1/36 ,  A61M37/00

CPC分类号： A61M1/0005 ,  A61M1/3613 ,  A61M1/0062

摘要： A double acting piston blood pump having distal and proximal manifolds that are connected by a cylinder having a piston reciprocating therein and dividing the cylinder into a proximal and distal chambers. The manifolds have chambers that are in fluid communication with the distal and proximal chambers of the cylinder and one way valves for controlling fluid flow from and to the cylinder chambers.

摘要翻译： 具有远端和近端歧管的双作用活塞血泵，其通过具有往复运动的活塞的气缸连接并将气缸分成近端和远端腔室。 歧管具有与气缸的远端和近端腔室流体连通的腔室，以及用于控制流体流向气缸室的单向阀。

公开(公告)号：US5318533A

公开(公告)日：1994-06-07

申请号：US839628

申请日：1992-02-21

申请人： Daniel O. Adams ,  David J. Haskvitz ,  Thomas J. Holman ,  William H. Penny ,  David J. Serdar ,  John M. Yates

发明人： Daniel O. Adams ,  David J. Haskvitz ,  Thomas J. Holman ,  William H. Penny ,  David J. Serdar ,  John M. Yates

IPC分类号： A61F2/958 ,  A61M29/00 ,  A61M5/00

CPC分类号： A61M25/10184 ,  A61M25/1018 ,  A61M25/10182 ,  A61M25/104 ,  A61M2205/50 ,  Y10S128/903

摘要： An inflation device includes a syringe forming a cylindrical chamber containing a plunger carrying a stopper or piston arrangement. The chamber is designed to contain an inflation fluid and is in fluid communication with the lumen of a balloon catheter. Movement of the plunger within the chamber will increase or decrease the pressure of the fluid within the chamber and lumen, thereby inflating or deflating the balloon at the distal end of the catheter. A pressure sensor is mounted to the housing in fluid communication with the lumen and is electrically connected to a battery-operated transmitter. The transmitter broadcasts signals representing pressure within the lumen and balloon to a remote receiver. The receiver includes a microprocessor containing a clock and operable to display time and pressure data. A flexible insulator strip is interposed between the battery and the transmitter circuit to prevent operation of the transmitter until desired by the cardiologist. The housing of the inflation device may be opened to remove the batteries for separate disposal and to render the circuit inoperative to prevent reuse. A look-up table associated with the microprocessor permits display of balloon diameter during the procedure.

摘要翻译： 膨胀装置包括一个注射器，该注射器形成一个圆筒形腔室，该圆柱形腔室包含一个承载塞子或 腔室被设计成容纳充气流体并且与球囊导管的内腔流体连通。 柱塞在腔室内的运动将增加或减小腔室和腔内的流体的压力，从而在导管的远端处膨胀或放气气囊。 压力传感器安装到外壳上，与腔体流体连通，并与电池供电的变送器电连接。 发射机将表示内腔和气球内的压力的信号广播到远程接收器。 接收机包括一个包含时钟并可操作以显示时间和压力数据的微处理器。 在电池和发射器电路之间插入柔性绝缘体条，以防止发射器的操作，直到心脏病专家期望。 可以打开充气装置的壳体以移除电池以进行单独处理，并使电路不起作用以防再次使用。 与微处理器相关联的查找表允许在该过程期间显示气球直径。

公开(公告)号：US09011516B2

公开(公告)日：2015-04-21

申请号：US11763740

申请日：2007-06-15

申请人： Jan Weber ,  Thomas J. Holman ,  Tracee Eidenschink

发明人： Jan Weber ,  Thomas J. Holman ,  Tracee Eidenschink

IPC分类号： A61F2/844 ,  A61F2/01 ,  A61F2/06 ,  A61F2/82

CPC分类号： A61F2/013 ,  A61F2/06 ,  A61F2/82 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/003

摘要： Medical devices, such as endoprostheses, and methods of making the devices are described. In some embodiments, a medical device includes an elongated hollow body formed of a polymeric matrix containing one or more regions of a pre-determined weight percent of carbon nanotubes in general alignment in a pre-determined orientation. The medical device can have a compressed state with a first transverse dimension and an expanded state with a second relatively greater transverse dimension.

摘要翻译： 描述医疗装置，例如内用假体，以及制造装置的方法。 在一些实施方案中，医疗装置包括由聚合物基质形成的细长中空体，其含有预定重量百分比的碳纳米管的一个或多个区域，以预定方向大致对准。 医疗装置可以具有第一横向尺寸的压缩状态和具有第二较大横向尺寸的膨胀状态。