公开(公告)号：US20130012467A1

公开(公告)日：2013-01-10

申请号：US13512255

申请日：2010-11-24

Applicant: Zeljko M. Prijovic ,  Yu-Lin Leu ,  Steve R. Roffler

Inventor： Zeljko M. Prijovic ,  Yu-Lin Leu ,  Steve R. Roffler

IPC: A61K31/706 ,  A61P35/00 ,  C07H15/26

CPC classification number: C07H15/203

Abstract: The invention relates to the synthesis of a second-generation camptothecin glucuronide prodrug (BQC-G) of a potent anticancer camptothecin derivative 5,6-dihydro-4H-benzo[de]quinoline-camptothecin (BQC). BQC-G was over 4000 times more water soluble than BQC, displayed good stability in human plasma and was an excellent substrate for enzymatic hydrolysis by bacterial and human β-glucuronidases. BQC-G was about 30 times less toxic than BQC, but was as toxic as BQC after hydrolysis of the glucuronide moiety by β-glucuronidase. In the presence of human serum albumin, BQC-G displayed lower cytotoxicity (IC50=1080 nM) but could be activated by β-glucuronidase to display potent activity (IC50=13.3 nM).

Abstract translation: 本发明涉及有效的抗癌喜树碱衍生物5,6-二氢-4H-苯并[de]喹啉 - 喜树碱（BQC）的第二代喜树碱葡糖苷酸前药（BQC-G）的合成。 BQC-G比BQC水溶液超过4000倍，在人血浆中表现出良好的稳定性，是细菌和人类 - 葡萄糖醛酸酶进行酶水解的优良底物。 BQC-G的毒性比BQC低约30倍，但与葡萄糖醛酸苷酶部分水解后，BQC毒性相当。 在人血清白蛋白存在下，BQC-G显示出更低的细胞毒性（IC50 = 1080nM），但可以被β-葡糖醛酸糖苷酶活化以显示有效活性（IC50 = 13.3nM）。

公开(公告)号：US08347461B2

公开(公告)日：2013-01-08

申请号：US12986363

申请日：2011-01-07

Applicant: Chia Hui Chen ,  Che-Hsien Lin ,  Tzu-Yu Lin

Inventor： Chia Hui Chen ,  Che-Hsien Lin ,  Tzu-Yu Lin

IPC: E05D7/00 ,  E05D3/06

CPC classification number: G06F1/1624

Abstract: Used in an electronic device comprising a cover panel and a base member, a slide cover mounting structure includes two hinges bilaterally mounted on the top wall of the base member, two sliding rail holders respectively connected to the pivot shafts of the hinges, two sliding rails bilaterally mounted on the bottom surface of the cover panel and respectively slidably coupled to a sliding groove on each of the sliding rail holder, two gears pivotally connected between fixed rails on the sliding rail holders, and two gear racks respectively mounted on the cover panel and meshed with the gears. Thus, the cover panel is prohibited from biasing during sliding movement, and turnable about the pivot shafts of the hinges from a horizontal position to a tilted position relative to the base member.

Abstract translation: 用于包括盖板和基座构件的电子设备中，滑盖安装结构包括两个铰链，两个铰链双向安装在基座的顶壁上，两个分别连接到铰链枢轴的滑轨架，两个滑轨 双向安装在盖板的底表面上，并分别可滑动地联接到每个滑轨支架上的滑动槽，两个齿轮枢转地连接在滑轨座上的固定轨道之间，以及分别安装在盖板上的两个齿条和 与齿轮啮合。 因此，盖板在滑动运动期间被禁止偏置，并且可绕铰链的枢转轴线从水平位置相对于基座部件转动到倾斜位置。

公开(公告)号：US08325512B2

公开(公告)日：2012-12-04

申请号：US13070977

申请日：2011-03-24

Applicant: Ching-Te Chuang ,  Wei-Chiang Shih ,  Hung-Yu Lee ,  Jihi-Yu Lin ,  Ming-Hsien Tu ,  Shyh-Jye Jou ,  Kun-Di Lee

Inventor： Ching-Te Chuang ,  Wei-Chiang Shih ,  Hung-Yu Lee ,  Jihi-Yu Lin ,  Ming-Hsien Tu ,  Shyh-Jye Jou ,  Kun-Di Lee

IPC: G11C11/00

CPC classification number: G11C11/413

Abstract: SRAM writing system and related apparatus are provided. The writing system of the invention has a dummy replica writing circuit, a negative pulse controller and at least a normal writing circuit; each normal writing circuit includes a write driver and a negative pulse supplier. While writing, the dummy replica writing circuit drives a dummy replica bit-line, such that the negative pulse controller generates a negative pulse control signal according to level of the dummy replica bit-line. In each writing circuit, when the write driver conducts to connect an associated bit-line to a bias end for driving a level transition, the negative pulse supplier switches the bias end from an operation voltage to a different negative pulse voltage according to the received negative pulse control signal.

Abstract translation: 提供了SRAM写入系统和相关装置。 本发明的写入系统具有虚拟副本写入电路，负脉冲控制器和至少一个正常写入电路; 每个正常写入电路包括写入驱动器和负脉冲供应器。 在写入时，虚拟副本写入电路驱动虚拟副本位线，使得负脉冲控制器根据虚拟副本位线的电平产生负脉冲控制信号。 在每个写入电路中，当写入驱动器将相关联的位线连接到用于驱动电平转换的偏置端时，负脉冲供应器根据接收到的负值将偏置端从工作电压切换到不同的负脉冲电压 脉冲控制信号。

公开(公告)号：US20120298991A1

公开(公告)日：2012-11-29

申请号：US13570758

申请日：2012-08-09

Applicant: Edward Yi Chang ,  Yu-Lin Hsiao ,  Jung-Chi Lu

Inventor： Edward Yi Chang ,  Yu-Lin Hsiao ,  Jung-Chi Lu

IPC: H01L29/20 ,  H01L29/22 ,  H01L29/161

CPC classification number: H01L29/2003 ,  H01L21/0237 ,  H01L21/02458 ,  H01L21/02505 ,  H01L21/0251 ,  H01L21/0254 ,  H01L21/02639 ,  H01L29/66462 ,  H01L29/778

Abstract: The present invention provides a method for forming a multilayer substrate having a gallium nitride layer, wherein a mesh layer having a plurality of openings is formed on a substrate, and a buffer layer, three aluminum gallium nitride layers with different aluminum concentrations and a gallium nitride layer are formed in sequence on the substrate in the openings. The three aluminum gallium nitride layers with different aluminum concentrations are capable of releasing stress, decreasing cracks on the surface of the gallium nitride layer and controlling interior defects, such that the present invention provides a gallium nitride layer with larger area, greater thickness, no cracks and high quality for facilitating the formation of high performance electronic components in comparison with the prior art. The present invention further provides a multilayer substrate having a gallium nitride layer.

Abstract translation: 本发明提供一种形成具有氮化镓层的多层基板的方法，其中在基板上形成具有多个开口的网格层，缓冲层，具有不同铝浓度的三个氮化铝镓层和氮化镓 层在开口中的基板上依次形成。 具有不同铝浓度的三个氮化铝铝层能够释放应力，减少氮化镓层表面上的裂纹并控制内部缺陷，使得本发明提供具有较大面积，更大厚度，无裂纹的氮化镓层 并且与现有技术相比有利于形成高性能电子部件的高质量。 本发明还提供了具有氮化镓层的多层基板。

公开(公告)号：USD671160S1

公开(公告)日：2012-11-20

申请号：US29425409

申请日：2012-06-22

Applicant: Cheng-Yu Lin

Designer： Cheng-Yu Lin

公开(公告)号：US20120274344A1

公开(公告)日：2012-11-01

申请号：US13240256

申请日：2011-09-22

Applicant: XIANG-BIAO CHEN ,  SHU-QI WU ,  YU-LIN LIU

Inventor： XIANG-BIAO CHEN ,  SHU-QI WU ,  YU-LIN LIU

IPC: G01R31/00

CPC classification number: G01R31/2839

Abstract: A test system includes a testing power supply unit which includes a rectifier and filter circuit and a voltage output circuit, a dropping voltage circuit which includes a primary coil and a secondary coil, a PWM regulator, and a control circuit. The rectifier and filter circuit receives an AC voltage and converts the AC voltage into a square wave signal. The primary coil is connected to the rectifier and filter circuit and receives the square wave signal. The secondary coil is connected to the voltage output circuit. The PWM regulator is connected to the primary coil. The PWM regulator generates a pulse signal to turn on and turn off the primary coil periodically. The control circuit is connected to the PWM regulator. The control circuit controls a duty cycle of the pulse signal to adjust time of the primary coil being on in a cycle.

Abstract translation: 测试系统包括测试电源单元，其包括整流器和滤波器电路和电压输出电路，包括初级线圈和次级线圈的降压电路，PWM调节器和控制电路。 整流滤波电路接收交流电压，将交流电压转换为方波信号。 初级线圈连接到整流器和滤波电路并接收方波信号。 次级线圈连接到电压输出电路。 PWM调节器连接到初级线圈。 PWM调节器产生一个脉冲信号，以便导通并周期性地关闭初级线圈。 控制电路连接到PWM调节器。 控制电路控制脉冲信号的占空比，以调整初级线圈在一个周期中接通的时间。

公开(公告)号：US20120272175A1

公开(公告)日：2012-10-25

申请号：US13273246

申请日：2011-10-14

Applicant: CHIN-YU LIN

Inventor： CHIN-YU LIN

IPC: G06F3/048

CPC classification number: G06F1/1694 ,  G06F3/0487 ,  G06F3/04886

Abstract: In a system and method for controlling a virtual keyboard of an electronic device, the virtual keyboard is generated and displayed on a touch screen of the electronic device. The method sets an angle threshold value, a movement amplitude and a movement direction of the virtual keyboard for each tilting angle of the electronic device. When the electronic device is in an edit mode and displays a middle keyboard area of the virtual keyboard, the method records an initial tilting angle and read the tilting angle of the electronic device. The method calibrates the read tilting angle to acquire actual tilting angle according to the initial tilting angle, and confirms the movement amplitude and movement direction of the virtual keyboard according to the actual tilting angle. The virtual keyboard is controlled to move according to the confirmed movement amplitude and towards the confirmed movement direction.

Abstract translation: 在用于控制电子设备的虚拟键盘的系统和方法中，虚拟键盘被生成并显示在电子设备的触摸屏上。 该方法为电子设备的每个倾斜角设置角度阈值，运动幅度和虚拟键盘的移动方向。 当电子设备处于编辑模式并显示虚拟键盘的中间键盘区域时，该方法记录初始倾斜角度并读取电子设备的倾斜角度。 该方法校准读取的倾斜角度以根据初始倾斜角度获得实际倾斜角度，并且根据实际倾斜角度确认虚拟键盘的移动幅度和移动方向。 控制虚拟键盘根据确定的移动幅度移动到朝向所确认的移动方向。

公开(公告)号：US08295627B2

公开(公告)日：2012-10-23

申请号：US12254103

申请日：2008-10-20

Applicant: Chih-Yu Lin ,  Chao-Chu Chang

Inventor： Chih-Yu Lin ,  Chao-Chu Chang

IPC: G06K9/40

CPC classification number: G09G3/3622 ,  G09G3/3413 ,  G09G2310/0235

Abstract: The present invention provides a circuit for controlling a color sequential liquid crystal display (LCD) and a method for controlling the same. The control circuit comprises a light-source driving circuit, a data driving circuit, and a scan driving circuit. The light-source driving circuit produces a driving signal for controlling the color sequential LCD to produce backlight with different colors. The data driving circuit produces a data signal and includes a plurality of data pulses. The scan driving signal produces a scan signal and includes a plurality of scan pulses corresponding to the plurality of data pulses, respectively. By controlling the pluralities of data pulses and scan pulses and the backlight, the color sequential LCD will display an image. The voltage levels of the pluralities of data pulses and scan pulses change according to different images. Thereby, power consumed by the control circuit can be reduced. In addition, color-mixing problems will be reduced according to the present invention.

Abstract translation: 本发明提供一种用于控制彩色液晶显示器（LCD）的电路及其控制方法。 控制电路包括光源驱动电路，数据驱动电路和扫描驱动电路。 光源驱动电路产生用于控制彩色顺序LCD以产生不同颜色的背光的驱动信号。 数据驱动电路产生数据信号并包括多个数据脉冲。 扫描驱动信号产生扫描信号并分别包括对应于多个数据脉冲的多个扫描脉冲。 通过控制多个数据脉冲和扫描脉冲以及背光源，彩色顺序LCD将显示图像。 多个数据脉冲和扫描脉冲的电压电平根据不同的图像而改变。 由此，可以减少由控制电路消耗的功率。 此外，根据本发明，混色问题将会降低。

公开(公告)号：US08294885B2

公开(公告)日：2012-10-23

申请号：US12854906

申请日：2010-08-12

Applicant: Tsung-Yu Lin

Inventor： Tsung-Yu Lin

IPC: G01B9/00

CPC classification number: G01B5/252

Abstract: An auxiliary device for measuring the coaxiality of a lens. The auxiliary device includes a cylindrical main body having a first surface and a flat second surface facing away the first surface, and a protrusion formed on the first surface and defining a reference convex surface. The second surface of the main body defines a position part. The position part is coaxial with the reference convex surface and configured to engage with the lens to measure the coaxiality of the lens.

Abstract translation: 用于测量透镜的同轴度的辅助装置。 辅助装置包括具有第一表面和背离第一表面的平坦的第二表面的圆柱形主体和形成在第一表面上并限定基准凸起表面的突起。 主体的第二表面限定了位置部分。 位置部分与参考凸表面同轴并且被配置为与透镜接合以测量透镜的同轴度。

公开(公告)号：US08291767B2

公开(公告)日：2012-10-23

申请号：US12506403

申请日：2009-07-21

Applicant: Chao-Chien Lee ,  Po-Yu Lin ,  Ting-Hung Su

Inventor： Chao-Chien Lee ,  Po-Yu Lin ,  Ting-Hung Su

IPC: G01M7/02 ,  G01H13/00 ,  G01H1/06

CPC classification number: G01M99/005 ,  G01M7/02

Abstract: A vibration testing device to test vibration strength and frequency generated by an electronic device, includes a base, a vibration contact member, a transmission member, and a resilient member attached to the transmission member. The base includes a receiving space to receive the electronic device and a receiving hole in communication with the receiving space. The transmission member extends through the receiving hole and is rigidly attached to the vibration contact member. During testing, the electronic device directly abuts an end portion of the transmission member so that the vibration strength and frequency generated by the electronic device are directly transmitted to the vibration contact member.

Abstract translation: 用于测试由电子设备产生的振动强度和频率的振动测试装置包括底座，振动接触构件，传动构件和附接到传动构件的弹性构件。 基座包括接收电子设备的接收空间和与接收空间通信的接收孔。 传动构件延伸穿过接收孔并刚性地附接到振动接触构件。 在测试期间，电子设备直接邻接传输部件的端部，使得由电子设备产生的振动强度和频率直接传递到振动接触部件。