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公开(公告)号：US20060073551A1
公开(公告)日：2006-04-06
申请号：US10243215
申请日：2002-09-12
申请人： Audrey Goddard , Austin Gurney , Jean Stephan , Colin Watanabe , William Wood
发明人： Audrey Goddard , Austin Gurney , Jean Stephan , Colin Watanabe , William Wood
CPC分类号： C07K14/47 , C07K14/705
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US20060073546A1
公开(公告)日：2006-04-06
申请号：US10213535
申请日：2002-08-07
申请人： David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin Gurney , James Pan , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood
发明人： David Botstein , Luc Desnoyers , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Austin Gurney , James Pan , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , William Wood
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060073544A1
公开(公告)日：2006-04-06
申请号：US10195883
申请日：2002-07-15
申请人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
发明人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060073476A1
公开(公告)日：2006-04-06
申请号：US10233134
申请日：2002-08-29
申请人： Kevin Baker , Luc Desnoyers , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Victoria Smith , Jean-Philippe Stephan , Colin Watanabe , William Wood
发明人： Kevin Baker , Luc Desnoyers , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Victoria Smith , Jean-Philippe Stephan , Colin Watanabe , William Wood
CPC分类号： C07K14/47 , C07K14/435 , C12N9/00 , C12N2510/00 , C12P21/02
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060051777A1
公开(公告)日：2006-03-09
申请号：US11084792
申请日：2005-03-18
申请人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
发明人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060003355A1
公开(公告)日：2006-01-05
申请号：US11122524
申请日：2005-05-04
申请人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
发明人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
IPC分类号： C12Q1/68
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20050227342A1
公开(公告)日：2005-10-13
申请号：US10165036
申请日：2001-10-19
申请人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Sophia Kuo , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , David Shelton , Timothy Stewart , Daniel Tumas , P. Williams , William Wood
发明人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Sophia Kuo , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , David Shelton , Timothy Stewart , Daniel Tumas , P. Williams , William Wood
CPC分类号： C07K14/705
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20050208585A1
公开(公告)日：2005-09-22
申请号：US10778394
申请日：2004-02-17
申请人： Camellia Adams , Paul Carter , Brian Fendly , Austin Gurney
发明人： Camellia Adams , Paul Carter , Brian Fendly , Austin Gurney
CPC分类号： C07K16/24 , A61K2039/505 , C07K16/2866 , C07K16/40 , C07K2317/21 , C07K2317/54 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/92
摘要： Various forms of c-mpl agonist antibodies are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Accordingly, these compounds may be used for treatment of thrombocytopenia.
摘要翻译： 显示各种形式的c-mpl激动剂抗体影响血细胞，特别是巨核细胞和巨核细胞祖细胞的复制，分化或成熟。 因此，这些化合物可用于治疗血小板减少症。
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公开(公告)号：US20050208523A1
公开(公告)日：2005-09-22
申请号：US10991287
申请日：2004-11-17
申请人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
发明人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
CPC分类号： C07H21/04 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20050202526A1
公开(公告)日：2005-09-15
申请号：US10180554
申请日：2002-06-25
申请人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
发明人： Kevin Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul Godowski , Austin Gurney , James Pan , Victoria Smith , Colin Watanabe , William Wood , Zemin Zhang
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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