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公开(公告)号：US20070254302A1
公开(公告)日：2007-11-01
申请号：US11766537
申请日：2007-06-21
申请人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
发明人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
IPC分类号： C12Q1/68
CPC分类号： C07H21/04 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20050208523A1
公开(公告)日：2005-09-22
申请号：US10991287
申请日：2004-11-17
申请人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
发明人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
CPC分类号： C07H21/04 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20050123925A1
公开(公告)日：2005-06-09
申请号：US10712892
申请日：2003-11-12
申请人： Avi Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin Gurney , Paul Polakis , Andrew Polson , William Wood , Thomas Wu , Zemin Zhang
发明人： Avi Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin Gurney , Paul Polakis , Andrew Polson , William Wood , Thomas Wu , Zemin Zhang
IPC分类号： A61K20060101 , A61K38/16 , A61K39/395 , C07K16/18 , C07K16/30 , C12N15/13 , C12P21/02 , C12Q1/68 , G01N33/574
CPC分类号： C07K16/30 , A61K2039/505
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20070031901A1
公开(公告)日：2007-02-08
申请号：US11457750
申请日：2006-07-14
申请人： Avi Ashkenazi , Audrey Goddard , Paul Godowski , Austin Gurney , Paul Polakis , P. Williams , William Wood , Thomas Wu , Zemin Zhang
发明人： Avi Ashkenazi , Audrey Goddard , Paul Godowski , Austin Gurney , Paul Polakis , P. Williams , William Wood , Thomas Wu , Zemin Zhang
IPC分类号： G01N33/574 , C07K16/30
CPC分类号： C07K16/30 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , G01N33/574
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20070054361A1
公开(公告)日：2007-03-08
申请号：US11486298
申请日：2006-07-13
申请人： Avi Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin Gurney , Paul Polakis , Andrew Polson , William Wood , Thomas Wu , Zemin Zhang
发明人： Avi Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin Gurney , Paul Polakis , Andrew Polson , William Wood , Thomas Wu , Zemin Zhang
CPC分类号： C07K16/30 , A61K2039/505
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20050164250A1
公开(公告)日：2005-07-28
申请号：US10994117
申请日：2004-11-19
申请人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Dong-Xiao Zhang
发明人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Dong-Xiao Zhang
IPC分类号： C07H21/04 , C07K14/47 , C07K14/82 , C12N1/18 , C12N9/64 , C12N15/09 , C12N15/74 , C12Q1/68 , C07K14/705 , G01N33/574
CPC分类号： C07H21/04 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译： 本发明涉及可用于哺乳动物肿瘤诊断和治疗的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20080096215A1
公开(公告)日：2008-04-24
申请号：US11926833
申请日：2007-10-29
申请人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Dong-Xiao Zhang
发明人： Avi Ashkenazi , Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Dong-Xiao Zhang
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： C07H21/04 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20050009105A1
公开(公告)日：2005-01-13
申请号：US10916250
申请日：2004-08-11
申请人： Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
发明人： Audrey Goddard , Austin Gurney , Paul Polakis , Victoria Smith , William Wood , Thomas Wu , Zemin Zhang
IPC分类号： A61K31/538 , A61K39/395 , C12Q1/68 , G01N33/53
CPC分类号： A61K31/538 , A61K31/7028 , C07K14/47 , C07K14/4748
摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20050112725A1
公开(公告)日：2005-05-26
申请号：US10978255
申请日：2004-10-29
申请人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Ivar Kljavin , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
发明人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Ivar Kljavin , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
IPC分类号： G01N33/50 , A01K67/027 , A61K38/00 , A61K38/17 , A61K39/00 , A61K39/395 , A61K45/00 , A61P1/04 , A61P1/16 , A61P3/10 , A61P5/14 , A61P7/00 , A61P7/06 , A61P9/00 , A61P11/02 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/06 , A61P19/02 , A61P25/00 , A61P29/00 , A61P37/02 , A61P37/06 , A61P37/08 , C07H21/04 , C07K14/435 , C07K14/47 , C07K14/54 , C07K16/18 , C07K16/24 , C07K16/40 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N15/09 , C12N15/12 , C12N15/85 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , G01N33/567 , G01N33/574
CPC分类号： G01N33/567 , A01K67/0275 , A01K2217/05 , A01K2227/105 , A01K2267/03 , C07K14/47 , C12N15/8509 , G01N33/57484 , G01N2800/52
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20060246540A1
公开(公告)日：2006-11-02
申请号：US11240891
申请日：2005-09-29
申请人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Ivar Kljavin , Jennie Mather , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
发明人： Avi Ashkenazi , Kevin Baker , David Botstein , Luc Desnoyers , Dan Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary Gerritsen , Audrey Goddard , Paul Godowski , Austin Gurney , Ivar Kljavin , Jennie Mather , Mary Napier , James Pan , Nicholas Paoni , Margaret Roy , Timothy Stewart , Daniel Tumas , Colin Watanabe , P. Williams , William Wood , Zemin Zhang
摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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