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91.发明申请System, devices, and methods including actively-controllable sterilizing excitation delivery implants 审中-公开系统，装置和方法，包括主动控制的消毒激励输送植入物公开(公告)号：US20090163965A1
公开(公告)日：2009-06-25
申请号：US12315884
申请日：2008-12-04
申请人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61N1/00
CPC分类号： A61F2/30 , A61F2/32 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/48 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2310/0097 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/14 , A61L2202/24 , A61M5/001 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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公开(公告)号：US20090101153A1
公开(公告)日：2009-04-23
申请号：US11975731
申请日：2007-10-18
申请人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61M16/00
CPC分类号： A61M16/0488 , A61B1/00016 , A61B1/0058 , A61B1/06 , A61B1/267 , A61B5/0013 , A61B8/12 , A61B8/4472 , A61B8/565 , A61M16/0418 , A61M2205/3306 , A61M2205/3569 , A61M2205/3592
摘要： Embodiments include a medical device, an apparatus, and a method. The medical device includes a tube portion shaped and sized for airway passage insertion and having at least one pathway therethrough; and a stylet of at least one shape-transforming material, configured for insertion in one of said at least one pathway; and at least one sensor carried by the tube portion and the stylet. The apparatus includes a stylet having a first end and a second end, at least a portion of the stylet including a shape-transforming material, the stylet being configured for insertion through an airway intubation structure having at least one pathway therethrough; and at least one sensor carried by the stylet in a proximity to the first end. The method includes capturing an image adjacent to an endotracheal tube proximate to an airway passage; and actuating, in response to the image, at least one shape-transformation of the endotracheal tube.
摘要翻译： 实施例包括医疗装置，装置和方法。 该医疗装置包括管状部分，其形状和尺寸用于气道通道插入并具有穿过其中的至少一个通路; 和至少一个形状转换材料的探针，其被配置用于插入所述至少一个通路之一; 以及由管部和探针支承的至少一个传感器。 所述设备包括具有第一端和第二端的探针，所述探针的至少一部分包括形状转换材料，所述探针被配置为插入穿过其中具有至少一个通路的气道插管结构; 以及在第一端附近由探针承载的至少一个传感器。 该方法包括捕获邻近气道通道的气管内管附近的图像; 并且响应于图像致动气管插管的至少一个形状变换。
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公开(公告)号：US20120134975A1
公开(公告)日：2012-05-31
申请号：US12228869
申请日：2008-08-13
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , William Gates , Alois A. Langer , Eric C. Leuthardt , Royce A. Levien , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , William Gates , Alois A. Langer , Eric C. Leuthardt , Royce A. Levien , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61K35/18 , A61P31/00 , C12N5/10 , A61P31/10 , A61P33/00 , C12N5/078 , A61P35/00 , A61P31/12
CPC分类号： A61K41/0071 , A61K35/18 , A61K47/6803 , A61K47/6898 , A61K2035/124 , B82Y5/00
摘要： Modified red blood cells are described. In an embodiment, the modified red blood cell includes a target-binding agent. Targeted delivery of imaging agents, drugs, and peptide and protein pharmaceuticals using modified red blood cells are described. Processes for preparing the modified red blood cells, pharmaceutical and diagnostic compositions containing the same and methods of diagnosis and treatment involving the modified red blood cells are described.
摘要翻译： 描述了改良的红细胞。 在一个实施方案中，修饰的红细胞包括靶结合剂。 描述了使用修饰的红细胞靶向递送成像剂，药物和肽和蛋白质药物。 描述了制备改性红细胞的方法，含有其的药物和诊断组合物以及涉及修饰的红细胞的诊断和治疗方法。
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公开(公告)号：US20100042072A1
公开(公告)日：2010-02-18
申请号：US12228893
申请日：2008-08-13
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , William Gates , Alois A. Langer , Eric C. Leuthardt , Royce A. Levien , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , William Gates , Alois A. Langer , Eric C. Leuthardt , Royce A. Levien , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： A61K35/18 , A61K41/0071 , A61K47/6901 , A61K49/0002 , A61K49/0097 , C12N5/0006 , C12N5/0641 , Y02A50/411 , Y02A50/463 , Y02A50/465 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/479 , Y02A50/481
摘要： Modified red blood cells are described. In an embodiment, the modified red blood cell includes a target-binding agent. Targeted delivery of imaging agents, drugs, and peptide and protein pharmaceuticals using modified red blood cells are described. Processes for preparing the modified red blood cells, pharmaceutical and diagnostic compositions containing the same and methods of diagnosis and treatment involving the modified red blood cells are described.
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公开(公告)号：US20140020787A1
公开(公告)日：2014-01-23
申请号：US13553403
申请日：2012-07-19
申请人： Michael H. Baym , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Conor L. Myhrvold , Nathan P. Myhrvold , Tony Pan , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Michael H. Baym , W. Daniel Hillis , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Conor L. Myhrvold , Nathan P. Myhrvold , Tony Pan , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： F17D1/00 , B65B1/00 , E21F1/00 , F17C2203/0325 , Y10T137/0318
摘要： A method of transporting liquefied breathing gases in underground mines includes providing a conduit system that extends within a mine shaft to a work space below ground where the conduit system includes an outlet positioned in the work space, delivering liquefied breathing gases through the conduit system, and vaporizing the liquefied breathing gases at the outlet of the conduit system.
摘要翻译： 在地下矿井中运送液化呼吸气体的方法包括提供一个导管系统，其在矿井内延伸到地下的工作空间，其中管道系统包括位于工作空间内的出口，输送液化的呼吸气体通过管道系统，以及 在管道系统的出口处蒸发液化的呼吸气体。
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公开(公告)号：US20130243275A1
公开(公告)日：2013-09-19
申请号：US13419819
申请日：2012-03-14
申请人： Michael H. Baym , Ralph G. Dacey, JR. , Roy P. Diaz , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Michael H. Baym , Ralph G. Dacey, JR. , Roy P. Diaz , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： G06F19/3406 , G06F19/00 , G16H40/20 , G16H40/63
摘要： Systems, devices, and methods are described for tracking, registering, etc. of medical staff, patients, instrumentation, events, or the like according to a treatment staging plan. For example a medical apparatus includes a right-patient verification device having an interrogation interface device that elicits at least one of identification data, authorization data, or treatment plan data from a medical procedure authorization device associated with a patient; and a right-site verification device that generates patient-specific treatment staging data consistent with the at least one of the identification data, the authorization data, or the treatment plan data.
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97.发明申请Systems, devices, and methods including catheters having components that are actively controllable between transmissive and reflective states 失效系统，装置和方法，包括具有在透射和反射状态之间可主动控制的部件的导管公开(公告)号：US20110152752A1
公开(公告)日：2011-06-23
申请号：US12927297
申请日：2010-11-10
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61M37/00
CPC分类号： A61M27/002 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/14 , A61L2202/24 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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98.发明申请Systems devices, and methods including catheters configured to monitor and inhibit biofilm formation 有权系统装置和方法，包括构造成监测和抑制生物膜形成的导管公开(公告)号：US20110152750A1
公开(公告)日：2011-06-23
申请号：US12927290
申请日：2010-11-10
申请人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： A61F2/30 , A61F2/32 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/48 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2310/0097 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787
摘要： Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
摘要翻译： 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物受试者的感染。
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99.发明申请Device, method, and system for neural modulation as vaccine adjuvant in a vertebrate subject 有权用于神经调制的装置，方法和系统，作为脊椎动物受试者中的疫苗佐剂公开(公告)号：US20110152748A1
公开(公告)日：2011-06-23
申请号：US12802812
申请日：2010-06-14
申请人： Gregory J. Della Rocca , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Jordin T. Kare , Muriel Y. Ishikawa , Eric C. Leuthardt , Stephen L. Malaska , Nathan P. Myhrvold , Paul Santiago , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Gregory J. Della Rocca , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Jordin T. Kare , Muriel Y. Ishikawa , Eric C. Leuthardt , Stephen L. Malaska , Nathan P. Myhrvold , Paul Santiago , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC分类号： A61M37/00
CPC分类号： A61M37/00 , A61F7/00 , A61K39/39 , A61M37/0092 , A61N1/303 , A61N1/306 , A61N1/32 , A61N1/36121 , A61N2/00 , A61N2/002 , A61N2/006 , A61N2/02 , A61N5/0622
摘要： A method for enhancing an immune response in a vertebrate subject is described. The method includes providing at least one energy stimulus configured to modulate one or more nervous system components of the vertebrate subject, and administering one or more immunogen to the vertebrate subject, wherein the at least one energy stimulus and the one or more immunogen are provided in a combination and in a temporal sequence sufficient to enhance an immune response in the vertebrate subject.
摘要翻译： 描述了一种增强脊椎动物受试者免疫应答的方法。 该方法包括提供至少一种能量刺激，其被配置成调节脊椎动物对象的一个或多个神经系统组分，以及向脊椎动物受试者施用一种或多种免疫原，其中所述至少一种能量刺激和所述一种或多种免疫原提供于 组合和时间序列，足以增强脊椎动物受试者的免疫应答。
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100.发明申请Device, Method, and system for neural modulation as vaccine adjuvant in a vertebrate subject 有权用于神经调制的装置，方法和系统作为脊椎动物受试者中的疫苗佐剂公开(公告)号：US20110150924A1
公开(公告)日：2011-06-23
申请号：US12655195
申请日：2009-12-22
申请人： Gregory J. Della Rocca , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Jordin T. Kare , Muriel Y. Ishikawa , Eric C. Leuthardt , Stephen L. Malaska , Nathan P. Myhrvold , Paul Santiago , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
发明人： Gregory J. Della Rocca , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Jordin T. Kare , Muriel Y. Ishikawa , Eric C. Leuthardt , Stephen L. Malaska , Nathan P. Myhrvold , Paul Santiago , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC分类号： A61M37/00 , A61F7/00 , A61K39/39 , A61M37/0092 , A61N1/303 , A61N1/306 , A61N1/32 , A61N1/36121 , A61N2/00 , A61N2/002 , A61N2/006 , A61N2/02 , A61N5/0622
摘要： A method for enhancing an immune response in a vertebrate subject is described. The method includes providing at least one energy stimulus configured to modulate one or more nervous system components of the vertebrate subject, and administering one or more immunogen to the vertebrate subject, wherein the at least one energy stimulus and the one or more immunogen are provided in a combination and in a temporal sequence sufficient to enhance an immune response in the vertebrate subject.
摘要翻译： 描述了一种增强脊椎动物受试者免疫应答的方法。 该方法包括提供至少一种能量刺激，其被配置成调节脊椎动物对象的一个或多个神经系统组分，以及向脊椎动物受试者施用一种或多种免疫原，其中所述至少一种能量刺激和所述一种或多种免疫原提供于 组合和时间序列，足以增强脊椎动物受试者的免疫应答。
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