公开(公告)号：US08444574B2

公开(公告)日：2013-05-21

申请号：US12396838

申请日：2009-03-03

申请人： Hans List ,  Irio G. Calasso ,  Joachim Hoenes ,  Hans-Peter Haar ,  Uwe Kraemer ,  Herbert Harttig ,  Volker Zimmer

发明人： Hans List ,  Irio G. Calasso ,  Joachim Hoenes ,  Hans-Peter Haar ,  Uwe Kraemer ,  Herbert Harttig ,  Volker Zimmer

IPC分类号： A61B5/00 ,  A61B17/32 ,  A61B17/14 ,  B65D81/00

CPC分类号： A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150175 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/15109 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15132

摘要： Lancing system comprising a needle and a lancing device The lancing device comprises a housing with a housing opening that is surrounded by a housing skin contact surface. A lancing depth reference element with a reference skin contact surface is adapted in such a manner that the reference skin contact surface at a reversal point of the lancing movement is in contact with the skin. The lancing depth is determined by the distance between the reference skin contact surface and the tip of the needle element at the reversal point of the lancing movement. The lancing depth reference element is in a stationary defined position relative to the reversal point of the lancing movement. The lancing depth reference element is adapted to stabilize the skin when pressed against the reference skin contact surface with respect to a skin deformation which occurs upon lancing of the skin.

摘要翻译： 包括针和穿刺装置的牵引系统。该穿刺装置包括壳体，该外壳具有由壳体皮肤接触表面包围的壳体开口。 具有参考皮肤接触表面的穿刺深度参考元件以使得在穿刺运动的反转点处的参考皮肤接触表面与皮肤接触的方式被适配。 穿刺深度由穿刺运动的反转点处的参考皮肤接触表面和针元件的尖端之间的距离确定。 穿刺深度参考元件相对于穿刺运动的反转点处于静止的限定位置。 穿刺深度参考元件适于当相对于在皮肤穿刺时发生的皮肤变形而压靠参照皮肤接触表面时稳定皮肤。

公开(公告)号：US20130066356A1

公开(公告)日：2013-03-14

申请号：US13619459

申请日：2012-09-14

申请人： Hans List ,  Christian Hoerauf ,  Frank Deck ,  Thomas Weiss ,  Michael Keil ,  Guenther Schmelzeisen-Redeker ,  Heinrich Fruhstorfer ,  Hans-Peter Haar ,  Uwe Kraemer ,  Joachim Hoenes ,  Karl Miltner

发明人： Hans List ,  Christian Hoerauf ,  Frank Deck ,  Thomas Weiss ,  Michael Keil ,  Guenther Schmelzeisen-Redeker ,  Heinrich Fruhstorfer ,  Hans-Peter Haar ,  Uwe Kraemer ,  Joachim Hoenes ,  Karl Miltner

IPC分类号： A61B17/34

CPC分类号： A61B5/1519 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150824 ,  A61B5/150954 ,  A61B5/15113

摘要： The invention relates to a puncturing system for generating a puncture wound for obtaining a sample of a body fluid, comprising a press-on part to be pressed onto a body part in which a puncture wound is to be generated, a triggering means with which a user can trigger a puncturing motion of a puncturing element after the press-on part is pressed on, and a testing facility for determining a test parameter on which a sample-obtaining probability depends. A securing facility is also provided that, in a locked state, locks the triggering means and, in a triggering state, releases the triggering means such that a puncturing motion can be triggered by actuation thereof. The securing facility is transitioned from the locked state to the triggering state by the testing facility when the test parameter determined by the testing facility meets defined minimum requirements.

摘要翻译： 本发明涉及一种用于产生用于获得体液样品的穿刺伤口的穿刺系统，包括：压制部件，其被压在其上将产生穿刺伤口的身体部位;触发装置，其中， 用户可以在按下按压部分之后触发穿刺元件的穿刺运动，以及用于确定取样概率所依赖的测试参数的测试设备。 还提供了一种固定装置，其处于锁定状态，锁定触发装置，并且在触发状态下释放触发装置，使得可以通过致动来触发穿刺运动。 当由测试设备确定的测试参数达到规定的最低要求时，固定设施由测试设备从锁定状态转换到触发状态。

公开(公告)号：US20130060114A1

公开(公告)日：2013-03-07

申请号：US13351496

申请日：2012-01-17

申请人： Hans-Peter Haar ,  Joachim Hoenes

发明人： Hans-Peter Haar ,  Joachim Hoenes

IPC分类号： A61B5/157 ,  C23F1/02 ,  A61B5/151

CPC分类号： A61B5/14532 ,  A61B2562/0295

摘要： A test element comprises a puncture element and a test pane. The puncture element has a tip for generating a wound and a capillary structure. The capillary structure extends from the tip to the test panel and has a fluid connection to the tip configured to allow body fluid to penetrate into the capillary structure. The test panel contains at least a part of the reagent system and is positioned in the test element adjacent to a part of the capillary structure of the puncture element in such a manner that body fluid penetrating into the capillary structure contacts a liquid entry side of the test panel. The test panel comprises a transparent support layer and a test layer applied to the support layer by coating, the side of the test panel facing away from the support layer forming its liquid entry side, which faces toward the capillary structure.

摘要翻译： 测试元件包括穿刺元件和测试窗格。 穿刺元件具有用于产生伤口和毛细管结构的尖端。 毛细管结构从尖端延伸到测试面板，并且具有与顶端的流体连接，构造成允许体液渗入毛细管结构。 测试面板包含至少一部分试剂系统，并且以穿过毛细结构的体液接触毛细结构的液体进入侧的方式定位在与穿刺元件的毛细结构的一部分相邻的测试元件中 测试面板。 测试面板包括透明支撑层和通过涂覆施加到支撑层的测试层，测试面板的背离形成其液体入口侧的支撑层的侧面朝向毛细结构。

公开(公告)号：US20120326949A1

公开(公告)日：2012-12-27

申请号：US13577050

申请日：2011-02-03

申请人： Jean-Michel Asfour ,  Hans-Peter Haar

发明人： Jean-Michel Asfour ,  Hans-Peter Haar

IPC分类号： G09G5/00 ,  G09G3/36

CPC分类号： G02B27/017 ,  G02B3/08 ,  G02B6/0006 ,  G02B6/0008 ,  G02B27/0172 ,  G02B2027/0118 ,  G02B2027/0132

摘要： The invention relates to a device for presenting information near the eyes, comprising a support (12) that can be carried on the head (10) of a user and comprising a monocular display unit (16) which is disposed on the support (12) and is positioned in a peripheral region of the field of vision of a first eye (14) of the user during use. According to a first aspect of the invention, a light-collecting unit (18, 20) on which ambient light can impinge is disposed on the support (12), and the light-collecting unit (18, 20) is coupled to the display unit (16) in order to illuminate same.

摘要翻译： 本发明涉及一种用于在眼睛附近呈现信息的装置，包括可承载在用户的头部（10）上的支架（12）并且包括设置在支撑件（12）上的单目显示单元（16） 并且在使用期间被定位在使用者的第一眼睛（14）的视野的外围区域中。 根据本发明的第一方面，其中环境光可以照射的集光单元（18,20）设置在支撑件（12）上，并且光收集单元（18,20）联接到显示器 单元（16）以照亮它。

公开(公告)号：US08328735B2

公开(公告)日：2012-12-11

申请号：US12105596

申请日：2008-04-18

申请人： Hans-Peter Haar ,  Joachim Hoenes ,  Carina Horn ,  Andreas Poredda

发明人： Hans-Peter Haar ,  Joachim Hoenes ,  Carina Horn ,  Andreas Poredda

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32 ,  B65D81/00

CPC分类号： A61B5/157 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150442 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150717 ,  A61B5/151 ,  A61B5/15105 ,  A61B5/15142 ,  A61B5/15188 ,  A61B2562/0295

摘要： An analytical system for detecting an analyte in a body fluid comprises a disposable integrated puncturing and analyzing element and a reusable analytical system. The integrated element includes a puncturing element having a tip for generating a puncture wound in a body part and an elongated flat test strip having a top side and a bottom side. The integrated element is held in a holder such that, in a sample application position of the test strip, the top side of the test strip is facing upward. A sample application area for manual application of a drop exiting from the puncture wound of the body part is provided on the top side of the test strip such that, in the sample application position, the drop is applied to the sample application area from directly above.

摘要翻译： 用于检测体液中的分析物的分析系统包括一次性集成穿刺和分析元件和可重复使用的分析系统。 集成元件包括具有用于产生卷绕在主体部分中的穿刺的尖端的穿刺元件和具有顶侧和底侧的细长平坦测试条。 集成元件保持在保持器中，使得在测试条的样品施加位置中，测试条的顶侧面向上。 在测试条的顶侧设置用于手动施加从身体部位的穿刺伤口出来的液滴的样品施加区域，使得在样品施加位置，将滴剂从上方施加到样品施用区域 。

公开(公告)号：US08251922B2

公开(公告)日：2012-08-28

申请号：US12755839

申请日：2010-04-07

申请人： Hans List ,  Hans-Peter Haar ,  George Bevan Kirby Meacham

发明人： Hans List ,  Hans-Peter Haar ,  George Bevan Kirby Meacham

IPC分类号： A61B5/00 ,  B65D81/00

CPC分类号： A61B5/150198 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150519 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15128 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15163 ,  A61B5/15176 ,  A61B5/157

摘要： Analysis system for automatically performing a skin prick analysis by pricking the skin for producing a sample of body liquid and detecting an analyte contained in the sample. The analysis system comprises a magazine with a plurality of compartments each containing a lancing element and an analysis element, and a reusable hand-held instrument having a drive assembly. The drive assembly is adapted for driving at least the following movements by manually generated mechanical force: a coupling movement by which one of the lancing elements is coupled to the drive assembly; a puncturing and sample collection movement of one of the lancing elements contained in the magazine and coupled to the drive assembly; and a remaganizing movement by which the test element is transported back into the compartment of the magazine.

摘要翻译： 用于通过穿刺皮肤以产生体液样品并检测样品中包含的分析物来自动执行皮肤点刺分析的分析系统。 分析系统包括具有多个隔室的盒，每个隔间包含穿刺元件和分析元件，以及具有驱动组件的可重复使用的手持式器械。 所述驱动组件适于通过手动产生的机械力来至少驱动以下运动：联接运动，通过所述联接运动，所述穿刺元件中的一个联接到所述驱动组件; 穿刺和样本收集运动，其中包含在所述盒中的所述穿刺元件之一并且联接到所述驱动组件; 以及将测试元件运送回料仓的隔间的再现运动。

公开(公告)号：US08114029B2

公开(公告)日：2012-02-14

申请号：US12619384

申请日：2009-11-16

申请人： Hans List ,  Hans-Peter Haar ,  George Bevan Kirby Meacham

发明人： Hans List ,  Hans-Peter Haar ,  George Bevan Kirby Meacham

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32

CPC分类号： A61B5/150198 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150511 ,  A61B5/15107 ,  A61B5/15117 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15176

摘要： An actuator for driving a test element is disclosed. The test element can comprise a lancet for perforating the skin of a living organism. The actuator can comprise an engaging part for engaging and driving the test element in a lancing motion. The actuator can further comprise a lancing actuator and a lancing spring. The lancing actuator can bias the lancing spring by executing a forward movement and thereby can exert a biasing force on the engaging part. The actuator can further comprise a latch element. The latch element can be a force-sensitive latch element for exerting a retention force to hold back the engaging part. The retention force can counteract the biasing force. The latch element can release the engaging part when the biasing force exerted by the lancing actuator exceeds the retention force exerted by the latch element, thereby allowing the test element to perform the lancing motion.

摘要翻译： 公开了用于驱动测试元件的致动器。 测试元件可以包括用于穿孔活体的皮肤的刺血针。 致动器可以包括用于以穿刺运动接合和驱动测试元件的接合部分。 致动器还可包括穿刺致动器和穿刺弹簧。 穿刺致动器可以通过执行向前运动来偏压穿刺弹簧，从而可以在接合部件上施加偏置力。 致动器还可以包括闩锁元件。 闩锁元件可以是用于施加保持力以阻止接合部分的力敏锁定元件。 保持力可以抵消偏置力。 当由穿刺致动器施加的偏压力超过由闩锁元件施加的保持力时，闩锁元件可以释放接合部件，从而允许测试元件执行穿刺运动。

公开(公告)号：US20110092855A1

公开(公告)日：2011-04-21

申请号：US12755839

申请日：2010-04-07

申请人： Hans List ,  Hans-Peter Haar ,  George Bevan Kirby Meacham

发明人： Hans List ,  Hans-Peter Haar ,  George Bevan Kirby Meacham

IPC分类号： A61B5/00 ,  A61B17/32

CPC分类号： A61B5/150198 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150519 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15128 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15163 ,  A61B5/15176 ,  A61B5/157

摘要： Analysis system for automatically performing a skin prick analysis by pricking the skin for producing a sample of body liquid and detecting an analyte contained in the sample. The analysis system comprises a magazine with a plurality of compartments each containing a lancing element and an analysis element, and a reusable hand-held instrument having a drive assembly. The drive assembly is adapted for driving at least the following movements by manually generated mechanical force: a coupling movement by which one of the lancing elements is coupled to the drive assembly; a puncturing and sample collection movement of one of the lancing elements contained in the magazine and coupled to the drive assembly; and a remaganizing movement by which the test element is transported back into the compartment of the magazine.

摘要翻译： 用于通过穿刺皮肤以产生体液样品并检测样品中包含的分析物来自动执行皮肤点刺分析的分析系统。 分析系统包括具有多个隔室的盒，每个隔间包含穿刺元件和分析元件，以及具有驱动组件的可重复使用的手持式器械。 所述驱动组件适于通过手动产生的机械力来至少驱动以下运动：联接运动，通过所述联接运动，所述穿刺元件中的一个联接到所述驱动组件; 穿刺和样本收集运动，其中包含在所述盒中的所述穿刺元件之一并且联接到所述驱动组件; 以及将测试元件运送回料仓的隔间的再现运动。

公开(公告)号：US20110009774A1

公开(公告)日：2011-01-13

申请号：US12879500

申请日：2010-09-10

申请人： Irio Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilifried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

发明人： Irio Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilifried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

IPC分类号： A61B5/151

CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150396 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/15151 ,  A61B5/15163

摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid. In one embodiment, the collection zone includes a plurality of holes, e.g., 3 or more holes, or 50 to 100 holes. The hole size may be small, e.g., having a diameter of 0.01 to 0.5 mm. The holes may or may not extend through the lancet. In some embodiments, the holes have a depth of 50 to 500 μm. In other embodiments, the collection zone is porous, or is a roughened area. The collection zone can take up a very small volume of body fluid, e.g., 3 to 10 nL, in a very short time period, e.g., less than 0.5 seconds. In other embodiments, the device further comprises a fluid receiving means spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially.

摘要翻译： 体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件。 在一个实施例中，收集区包括多个孔，例如3个或更多个孔，或50至100个孔。 孔尺寸可以较小，例如具有0.01至0.5mm的直径。 这些孔可以延伸穿过刺血针也可能不延伸穿过刺血针。 在一些实施例中，孔的深度为50至500μm。 在其它实施方案中，收集区是多孔的，或者是粗糙区域。 收集区可以在非常短的时间段（例如小于0.5秒）内占据非常小体积的体液，例如3至10nL。 在其他实施例中，该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液最初不会接触流体接收装置。

公开(公告)号：US07819822B2

公开(公告)日：2010-10-26

申请号：US11470368

申请日：2006-09-06

申请人： Irio Guiseppe Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilfried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

发明人： Irio Guiseppe Calasso ,  Patrick Griss ,  Emad Sarofim ,  Rainer Jaeggi ,  Uwe Kraemer ,  Dave Hasker ,  Volker Zimmer ,  Wilfried Schmid ,  Otto Fuerst ,  Hans List ,  Hans-Peter Haar ,  Theo Arnitz ,  Steven N. Roe

IPC分类号： A61B5/00

CPC分类号： A61B5/1411 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150282 ,  A61B5/150358 ,  A61B5/150396 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/15045 ,  A61B5/150503 ,  A61B5/15151 ,  A61B5/15163

摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid, and the device further comprising a fluid receiving means remote spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially. The collection zone takes up a very small volume of body fluid of about 10 to 500 nl in a very short time period of less than 0.5 seconds. The fluid receiving means may have a test zone for performing an analytical reaction. Fluid sample from the collection zone is automatically or manually transported to the fluid receiving means to contact the fluid with the test zone.

摘要翻译： 体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件，并且该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液不会接触流体接收装置 原来。 收集区在小于0.5秒的非常短的时间段内占据非常小体积的体液约10至500nl。 流体接收装置可以具有用于进行分析反应的测试区域。 来自收集区的流体样品被自动或手动地输送到流体接收装置以使流体与测试区接触。