利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

274 条记录 (耗时 0.058 秒)

    Device and method for delivery of a drug depot near the nerve
    91.
    发明授权
    Device and method for delivery of a drug depot near the nerve 有权
    用于在神经附近递送药物库的装置和方法

    公开(公告)号：US08715223B2

    公开(公告)日：2014-05-06

    申请号：US12507197

    申请日：2009-07-22

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61M31/00

    CPC分类号： A61M37/0069 ,  A61B5/04001 ,  A61B5/4839 ,  A61B5/4893

    摘要： Drug depot delivery devices and methods are provided for delivering one or more drug depots in close proximity to the nerve of a patient with or without repositioning the cannula. The device includes an electronic monitor for detecting the proximity of the tip of the cannula to a nerve. In some embodiments, a method of delivering a drug depot is provided by detecting the nerve and delivering the drug depot near the nerve.

    摘要翻译： 提供药物库递送装置和方法用于在有或者没有重新定位插管的情况下递送一个或多个药物库，其紧邻患者的神经。 该装置包括用于检测套管尖端与神经的接近的电子监视器。 在一些实施方案中，通过检测神经并在神经附近递送药物库来提供递送药物库的方法。

    BONE DELIVERY SYSTEMS INCLUDING HOLDING AND FILLING DEVICES AND METHODS
    93.
    发明申请
    BONE DELIVERY SYSTEMS INCLUDING HOLDING AND FILLING DEVICES AND METHODS 有权

    公开(公告)号：US20130261634A1

    公开(公告)日：2013-10-03

    申请号：US13438590

    申请日：2012-04-03

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61B17/58

    CPC分类号： A61F2/2846 ,  A61F2002/2835 ,  A61F2002/30462 ,  A61F2002/30586 ,  A61F2002/30588 ,  A61F2002/30729 ,  A61F2210/0004

    摘要： A delivery system comprising a biodegradable single or multi compartment covering is provided. The covering can be a mesh bag including a pre-attached detachable holding member surrounding the opening of at least one compartment and a pre-attached removable filling member configured to fit within the opening of the at least one compartment. The opening of the bag can include a closing member. The pre-attached detachable holding member can be a collar including finger grips and is used to hold the bag in one position while filling it. In some embodiments, the pre-attached detachable filling member can be a funnel for loading the mesh bag with bone graft material. Once the covering is filled, the holding member and filling member can be removed and the covering is closed with a closing member such as a drawstring. A method of treatment utilizing the delivery system is also provided.

    DRUG DELIVERY SYSTEM
    94.
    发明申请
    DRUG DELIVERY SYSTEM 有权
    药物递送系统

    公开(公告)号：US20130261596A1

    公开(公告)日：2013-10-03

    申请号：US13432129

    申请日：2012-03-28

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61M5/31

    CPC分类号： A61M5/31 ,  A61M25/0108 ,  A61M37/0069

    摘要： A drug delivery device for delivering a drug pellet to a site beneath the skin of a patient is provided, the drug delivery device including a housing having a chamber configured to hold at least one drug pellet, the chamber having a loading end and a delivery end, the loading end of the chamber having an opening for receiving a plunger and a drug pellet and the delivery end having an opening for receiving the plunger and passage of the drug pellet. The housing includes at least one hole substantially perpendicular to the chamber and formed to at least partially intersect the chamber. A capture pin is provided configured to be receivable within the at least one hole.

    摘要翻译： 提供了一种用于将药物丸粒输送到患者皮肤下方的部位的药物递送装置，所述药物递送装置包括具有被配置为保持至少一个药物丸粒的腔室的壳体，所述腔室具有装载端和输送端 所述腔室的装载端具有用于容纳柱塞和药丸的开口，并且所述输送端具有用于容纳所述柱塞和所述药丸的通道的开口。 所述壳体包括至少一个基本上垂直于所述腔室并且形成为至少部分地与所述腔室相交的孔。 捕获销被配置为可接收在至少一个孔内。

    Resorbable matrix having elongated particles
    95.
    发明授权
    Resorbable matrix having elongated particles 有权
    具有细长颗粒的可再吸收基质

    公开(公告)号：US08475824B2

    公开(公告)日：2013-07-02

    申请号：US12693770

    申请日：2010-01-26

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61F2/00

    CPC分类号： A61L27/54 ,  A61K38/1875 ,  A61L27/446 ,  A61L27/46 ,  A61L27/58 ,  A61L2300/414 ,  C08L89/06

    摘要： Compression resistant matrices and methods are provided that have elongated particles embedded therein. The compression resistant matrices provide improved stability and mechanical strength and resists shifting, extrusion and rotation after implantation. In some embodiments, the matrices provided reduce or prevent surface compression of the implantable matrix which will cause unwanted increased amounts of growth factor (e.g., bone morphogenic protein) to leak from the matrix.

    摘要翻译： 提供具有嵌入其中的细长颗粒的抗压基质和方法。 耐压基质提供改进的稳定性和机械强度，并且抵抗植入后的移位，挤出和旋转。 在一些实施方案中，所提供的基质降低或防止可植入基质的表面压缩，这将导致生长因子（例如，骨形态发生蛋白）不必要地增加从基质中泄漏。

    Bone augmentation device and method
    96.
    发明授权
    Bone augmentation device and method 有权
    骨增强装置及方法

    公开(公告)号：US08470046B2

    公开(公告)日：2013-06-25

    申请号：US13093144

    申请日：2011-04-25

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61F2/02

    CPC分类号： A61C8/0006 ,  A61C8/0028

    摘要： A bone augmentation device includes at least one axial member defining a longitudinal axis and a plurality of transverse members. Each transverse member extends from a first end, or removably connected to the at least one axial member to a second end configured for fixation with bone. The transverse members are spaced apart and disposed along the longitudinal axis. The at least one axial member and the transverse members are disposed in a configuration to define a bone graft cavity. Methods of use are also disclosed.

    摘要翻译： 骨增强装置包括限定纵向轴线和多个横向构件的至少一个轴向构件。 每个横向构件从第一端部延伸，或者可移除地连接到至少一个轴向构件，构造成用于与骨固定的第二端。 横向构件沿着纵向轴线间隔开并设置。 至少一个轴向构件和横向构件设置成构造以限定骨移植物腔。 还公开了使用方法。

    Bone replacement material mixing and delivery devices and methods of use
    99.
    发明授权
    Bone replacement material mixing and delivery devices and methods of use 有权
    骨置换材料的混合和输送装置及使用方法

    公开(公告)号：US08408250B2

    公开(公告)日：2013-04-02

    申请号：US12818300

    申请日：2010-06-18

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： B65B1/04

    CPC分类号： A61B17/8833 ,  A61B2017/8838

    摘要： Bone cement mixing and delivery devices and methods of using the devices are provided. The bone cement mixing and delivery devices and methods comprise a container having a bottom opening that can be sealed by a spacer in a syringe where movement of the plunger of the syringe moves the spacer away from the bottom opening in the container to dispense bone cement into the syringe. In some embodiments, the devices and methods increases efficiency and reduce the mess associated with transferring the bone cement to the syringe for delivery to a patient.

    摘要翻译： 提供了骨水泥混合输送装置及其使用方法。 骨水泥混合和递送装置和方法包括具有底部开口的容器，该底部开口可以通过注射器中的间隔件密封，其中注射器的柱塞的移动使垫片远离容器中的底部开口移动以将骨水泥分配到 注射器。 在一些实施例中，装置和方法提高了效率并减少了将骨粘固剂转移到注射器以用于递送给患者的混乱。

    Highly-mineralized osteogenic sponge compositions and uses thereof
    100.
    发明授权
    Highly-mineralized osteogenic sponge compositions and uses thereof 有权
    高度成矿的成骨海绵组合物及其用途

    公开(公告)号：US08399010B2

    公开(公告)日：2013-03-19

    申请号：US13369929

    申请日：2012-02-09

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61K38/00 ,  A61K38/16 ,  A61K38/17 ,  A61K38/18 ,  A61K38/39

    CPC分类号： A61L27/56 ,  A61K38/1875 ,  A61L27/227 ,  A61L27/46 ,  A61L2430/02 ,  C08L89/06

    摘要： Osteogenic sponge compositions having enhanced osteoinductive properties for use in bone repair are described. The compositions include a quickly resorbable porous carrier, a more slowly resorbed mineral scaffold and an osteogenic factor, preferably a bone morphogenetic protein. The compositions enable increased osteoinductive activity while retaining a reliable scaffold for the formation of new bone at an implant site. Methods for therapeutic use of the compositions are also described.

    摘要翻译： 描述了用于骨修复的具有增强的骨诱导性质的成骨海绵组合物。 组合物包括快速可吸收的多孔载体，更缓慢吸收的矿物支架和成骨因子，优选骨形态发生蛋白。 组合物能够增加骨诱导活性，同时保留用于在植入部位形成新骨的可靠的支架。 还描述了治疗性使用组合物的方法。