公开(公告)号：US20070185171A1

公开(公告)日：2007-08-09

申请号：US11584151

申请日：2006-10-20

Applicant: Julie Germain ,  Benny Askew ,  David Bauer ,  Deborah Choquette ,  Lucian Dipietro ,  Russell Graceffa ,  Jean-Christophe Harmange ,  Qi Huang ,  Joseph Kim ,  Daniel La ,  Aiwen Li ,  Nobuko Nishimura ,  Rana Nomak ,  Vinod Patel ,  Michele Potashman ,  Babak Riahi ,  Thomas Storz ,  Simon Van Der Plas ,  Kevin Yang ,  Chester Yuan

Inventor： Julie Germain ,  Benny Askew ,  David Bauer ,  Deborah Choquette ,  Lucian Dipietro ,  Russell Graceffa ,  Jean-Christophe Harmange ,  Qi Huang ,  Joseph Kim ,  Daniel La ,  Aiwen Li ,  Nobuko Nishimura ,  Rana Nomak ,  Vinod Patel ,  Michele Potashman ,  Babak Riahi ,  Thomas Storz ,  Simon Van Der Plas ,  Kevin Yang ,  Chester Yuan

IPC: C07D209/04 ,  C07D213/16

CPC classification number: C07D471/04 ,  C07D487/04

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract translation: 所选化合物对于预防和治疗诸如血管生成介导的疾病等疾病是有效的。 本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

公开(公告)号：US07196104B2

公开(公告)日：2007-03-27

申请号：US10631423

申请日：2003-07-30

Applicant: Benny C. Askew, Jr. ,  Frenel F. De Morin ,  Andrew Hague ,  Ellen Laber ,  Aiwen Li ,  Gang Liu ,  Patricia Lopez ,  Rana Nomak ,  Vincent Santora ,  Christopher Tegley ,  Kevin Yang

Inventor： Benny C. Askew, Jr. ,  Frenel F. De Morin ,  Andrew Hague ,  Ellen Laber ,  Aiwen Li ,  Gang Liu ,  Patricia Lopez ,  Rana Nomak ,  Vincent Santora ,  Christopher Tegley ,  Kevin Yang

IPC: A61K31/44 ,  C07D417/12

CPC classification number: C07D213/75 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08 ,  C07D417/04 ,  C07D417/12 ,  C07D417/14 ,  C07D453/06 ,  C07D471/04 ,  C07D491/10

Abstract: Selected novel urea compounds are effective for prophylaxis and treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stoke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract translation: 所选择的新型尿素化合物对于预防和治疗诸如细胞增殖或细胞凋亡介导的疾病的疾病是有效的。 本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及stoke，癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

公开(公告)号：US20060025400A1

公开(公告)日：2006-02-02

申请号：US11182216

申请日：2005-07-15

Applicant: Benny Askew ,  Toshihiro Aya ,  Kaustav Biswas ,  Guolin Cai ,  Jian Chen ,  Nianhe Han ,  Qingyian Liu ,  Thomas Nguyen ,  Nobuko Nishimura ,  Rana Nomak ,  Tanya Peterkin ,  Wenyuan Qian ,  Kevin Yang ,  Chester Yuan ,  Jiawang Zhu ,  Derin D' Amico ,  Jason Human ,  Qi Huang

Inventor： Benny Askew ,  Toshihiro Aya ,  Kaustav Biswas ,  Guolin Cai ,  Jian Chen ,  Nianhe Han ,  Qingyian Liu ,  Thomas Nguyen ,  Nobuko Nishimura ,  Rana Nomak ,  Tanya Peterkin ,  Wenyuan Qian ,  Kevin Yang ,  Chester Yuan ,  Jiawang Zhu ,  Derin D' Amico ,  Jason Human ,  Qi Huang

IPC: A61K31/55 ,  A61K31/497 ,  C07D403/02

CPC classification number: C07D221/10 ,  C07D221/08 ,  C07D239/74 ,  C07D241/08 ,  C07D243/08 ,  C07D249/08 ,  C07D295/135 ,  C07D311/96 ,  C07D335/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D417/12 ,  C07D491/04

Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract translation: 所选化合物对于治疗疼痛和疾病如炎症介导的疾病是有效的。 本发明包括新的化合物，类似物，前药和其药学上可接受的衍生物，用于预防和治疗疾病和其它疾病或涉及疼痛，炎症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

公开(公告)号：US20050054670A1

公开(公告)日：2005-03-10

申请号：US10926238

申请日：2004-08-24

Applicant: Christopher Tegley ,  Jeffrey Adams ,  Benny Askew ,  Michael Croghan ,  Daniel Elbaum ,  Julie Germain ,  Gregory Habgood ,  Scott Harried ,  Aiwen Li ,  Nobuko Nishimura ,  Rana Nomak ,  Andrew Tasker ,  Kevin Yang

Inventor： Christopher Tegley ,  Jeffrey Adams ,  Benny Askew ,  Michael Croghan ,  Daniel Elbaum ,  Julie Germain ,  Gregory Habgood ,  Scott Harried ,  Aiwen Li ,  Nobuko Nishimura ,  Rana Nomak ,  Andrew Tasker ,  Kevin Yang

IPC: A61P29/00 ,  A61P35/00 ,  C07D401/12 ,  C07D401/14 ,  C07D471/02 ,  A61K31/4035 ,  A61K31/4745

CPC classification number: C04B35/632 ,  C07D401/12 ,  C07D401/14

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract translation: 所选化合物对于预防和治疗诸如血管生成介导的疾病等疾病是有效的。 本发明包括新颖的化合物，类似物，前药和药学上可接受的盐，用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。 本发明还涉及制备这些化合物的方法以及在这些方法中有用的中间体。

公开(公告)号：US5068576A

公开(公告)日：1991-11-26

申请号：US565711

申请日：1990-08-13

Applicant: Feng-Kang Hu ,  Chung M. Lau ,  Kevin Yang ,  Joshau S. Zhu ,  Peter S. Shen ,  Thomas C. Jednacz

Inventor： Feng-Kang Hu ,  Chung M. Lau ,  Kevin Yang ,  Joshau S. Zhu ,  Peter S. Shen ,  Thomas C. Jednacz

IPC: H02M5/257 ,  H05B41/36 ,  H05B41/392

CPC classification number: H02M5/2576 ,  H05B41/36 ,  H05B41/3927 ,  Y10S315/04

Abstract: A dimming ballast system wherein the light output of the lamp is controlled by a remote source. The ballast output voltage is regulated by a voltage control feedback loop, the dimming function being achieved by varying the set point of the control loop. The remote control signal, coded by interrupting the current flow to the ballast for a short period, is processed digitally by a microcomputer which generates information to vary the control set point. Circuit means are provided to control the filament voltage of the fluorescent lamps such that as the lamps are dimmed down, the filament voltage is maintained or slightly increased, thus prolonging lamp life and stabilizing the lamp light output.

Abstract translation: 调光镇流器系统，其中灯的光输出由远程源控制。 镇流器输出电压由电压控制反馈回路调节，调光功能通过改变控制回路的设定点来实现。 通过中断流入镇流器的电流短时间编码的遥控信号由产生信息以改变控制设定点的微计算机数字地处理。 提供电路装置以控制荧光灯的灯丝电压，使得当灯被调暗时，灯丝电压保持或略微增加，从而延长灯的寿命并稳定灯的光输出。