公开(公告)号：US20100114639A1

公开(公告)日：2010-05-06

申请号：US12596613

申请日：2008-04-17

申请人： Claus Leiendecker ,  Carsten Müller ,  Elke Schulte ,  Wei Zhang

发明人： Claus Leiendecker ,  Carsten Müller ,  Elke Schulte ,  Wei Zhang

IPC分类号： G06Q10/00 ,  A61M1/14 ,  G06F15/16

CPC分类号： A61M1/14 ,  A61B5/002 ,  A61B5/021 ,  A61B5/024 ,  A61B90/90 ,  A61B90/98 ,  A61B2017/00119 ,  A61B2017/00221 ,  A61B2017/00482 ,  A61B2562/08 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/6018 ,  A61M2205/6054 ,  A61M2205/8237 ,  A61M2205/84 ,  G06F19/00 ,  G06Q50/24 ,  G16H10/60

摘要： An assembly includes at least two medical treatment units, each of which can be allocated to a patient and at least two peripheral devices, each of which can be allocated to a patient. The peripheral devices and the treatment units have means for allocating a peripheral device to a treatment unit and means for verifying the allocation of a peripheral device to a patient. To allocate a peripheral device to a treatment unit, the peripheral device is placed by operators in a receiving unit belonging to the treatment unit. Said receiving unit is preferably designed as a charging station for the battery of the peripheral device. In the event of a successful allocation of peripheral device and patient, confirmed by the receipt of physiological data of the patient, the operators verify the correct allocation of a peripheral device to the patient and must confirm the correct allocation by confirmation means. The peripheral device is only released if the operator has confirmed the correct allocation, preferably within a predefined time period.

摘要翻译： 组件包括至少两个医疗单元，每个医疗单元可以分配给患者和至少两个外围设备，每个外围设备可以分配给患者。 外围设备和治疗单元具有用于将外围设备分配给治疗单元的装置和用于验证外围设备对患者的分配的装置。 为了将外围设备分配给治疗单元，外围设备由操作员放置在属于治疗单元的接收单元中。 所述接收单元优选地被设计为用于外围设备的电池的充电站。 在外部设备和患者的成功分配的情况下，通过接收患者的生理数据确认，操作者验证外部设备对患者的正确分配，并且必须通过确认手段确认正确的分配。 如果操作者已经确定了正确的分配，则优选地在预定的时间段内，外围设备才被释放。

公开(公告)号：US20100098634A1

公开(公告)日：2010-04-22

申请号：US12509259

申请日：2009-07-24

申请人： Hartmuth C. Kolb ,  Joseph C. Walsh ,  Wei Zhang ,  Umesh B. Gangadharmath ,  Dhanalakshmi Kasi ,  Kai Chen ,  Anjana Sinha ,  Eric Wang ,  Gang Chen ,  Peter J.H. Scott ,  Henry Clifton Padgett ,  Qianwa Liang ,  Zhiyong Gao ,  Tieming Zhao ,  Chunfang Xia

发明人： Hartmuth C. Kolb ,  Joseph C. Walsh ,  Wei Zhang ,  Umesh B. Gangadharmath ,  Dhanalakshmi Kasi ,  Kai Chen ,  Anjana Sinha ,  Eric Wang ,  Gang Chen ,  Peter J.H. Scott ,  Henry Clifton Padgett ,  Qianwa Liang ,  Zhiyong Gao ,  Tieming Zhao ,  Chunfang Xia

IPC分类号： A61K51/04 ,  C07D277/02 ,  C07D495/02 ,  C07D209/34 ,  C07D221/02 ,  C07D455/00 ,  C07D417/00 ,  C07D487/00 ,  C07D401/02 ,  C07D471/00 ,  C07D209/82 ,  C07D307/91 ,  A61P25/28 ,  G01N33/53

CPC分类号： C07D417/14 ,  A61K51/0406 ,  A61K51/0453 ,  A61K51/0455 ,  A61K51/0459 ,  C07D277/64 ,  C07D277/68 ,  C07D417/04 ,  C07D471/04 ,  C07D498/14 ,  C07D513/04 ,  C07D513/14

摘要： Provided herein are compounds and compositions which comprise the formulae as disclosed herein, wherein the compound is an amyloid binding compound. An amyloid binding compound according to the invention may be administered to a patient in amounts suitable for in vivo imaging of amyloid deposits, and distinguish between neurological tissue with amyloid deposits and normal neurological tissue. Amyloid probes of the invention may be used to detect and quantitate amyloid deposits in diseases including, for example, Down's syndrome, familial Alzheimer's Disease. In another embodiment, the compounds may be used in the treatment or prophylaxis of neurodegenerative disorders. Also provided herein are methods of allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing a neurodegenerative disease.

摘要翻译： 本文提供了包含本文公开的式的化合物和组合物，其中所述化合物是淀粉样蛋白结合化合物。 根据本发明的淀粉样蛋白结合化合物可以以适于淀粉样蛋白沉积物的体内成像的量施用于患者，并且可以区分具有淀粉样沉积物的神经组织和正常神经组织。 本发明的淀粉样蛋白探针可用于检测和定量疾病中的淀粉样蛋白沉积物，包括例如唐氏综合症，家族性阿尔茨海默氏病。 在另一个实施方案中，所述化合物可用于治疗或预防神经变性疾病。 本文还提供了允许化合物分布到脑组织中并对脑组织成像的方法，其中与正常对照结合水平相比，化合物与脑组织的结合增加指示哺乳动物患有或 有发展神经变性疾病的风险。

公开(公告)号：US07688199B2

公开(公告)日：2010-03-30

申请号：US11555992

申请日：2006-11-02

申请人： Wei Zhang ,  Chao-Hsin Lin

发明人： Wei Zhang ,  Chao-Hsin Lin

IPC分类号： G08B1/08 ,  G08B21/00 ,  G08B25/00

CPC分类号： G08B17/00 ,  A62C3/08 ,  G08B31/00

摘要： A detection system may include at least one sensor located in an enclosable space, each sensor being configured to detect at least one environmental feature and provide a corresponding at least one environmental feature signal. The system may process the at least one environmental feature signal and provide at least one processed feature signal, the at least one processed feature signal corresponding to a transformed at least one environmental feature signal. The system may further provide a hosted function configured to provide instructions for processing, the hosted function comprising a computational algorithm adapted to perform numerical transformation operations based on the at least one environmental feature signal, the hosted function being configured to provide a map image based on the at least one processed feature signal.

摘要翻译： 检测系统可以包括位于可封闭空间中的至少一个传感器，每个传感器被配置成检测至少一个环境特征并提供对应的至少一个环境特征信号。 所述系统可以处理所述至少一个环境特征信号并提供至少一个经处理的特征信号，所述至少一个经处理的特征信号对应于经变换的至少一个环境特征信号。 所述系统还可以提供被配置为提供用于处理的指令的托管功能，所述托管功能包括适于基于所述至少一个环境特征信号执行数字变换操作的计算算法，所述托管功能被配置为基于 所述至少一个经处理的特征信号。

公开(公告)号：US20100074551A1

公开(公告)日：2010-03-25

申请号：US12235488

申请日：2008-09-22

申请人： Zhouchen Lin ,  Wei Zhang

发明人： Zhouchen Lin ,  Wei Zhang

IPC分类号： G06K9/40

CPC分类号： G06K9/40 ,  G06T5/001 ,  G06T7/10 ,  G06T2207/20081

摘要： Partial differential equations (PDEs) are used in the invention for various problems in computer the vision space. The present invention provides a framework for learning a system of PDEs from real data to accomplish a specific vision task. In one embodiment, the system consists of two PDEs. One controls the evolution of the output. The other is for an indicator function that helps collect global information. Both PDEs are coupled equations between the output image and the indicator function, up to their second order partial derivatives. The way they are coupled is suggested by the shift and rotational invariance that the PDEs should hold. The coupling coefficients are learnt from real data via an optimal control technique. The invention provides learning-based PDEs that make a unified framework for handling different vision tasks, such as edge detection, denoising, segementation, and object detection.

摘要翻译： 局部微分方程（PDE）用于本发明的计算机视觉空间中的各种问题。 本发明提供了一种用于从实际数据学习PDE系统以完成特定视觉任务的框架。 在一个实施例中，系统由两个PDE组成。 一个控制输出的演变。 另一个是用于帮助收集全球信息的指标功能。 两个PDE是输出图像和指示符函数之间的耦合方程，直到它们的二阶偏导数。 它们耦合的方式是由PDE应该保持的移动和旋转不变性来提出的。 通过最优控制技术从实数数据中学习耦合系数。 本发明提供了基于学习的PDE，其构成用于处理不同视觉任务的统一框架，例如边缘检测，去噪，分割和对象检测。

公开(公告)号：US07672494B2

公开(公告)日：2010-03-02

申请号：US11419980

申请日：2006-05-23

申请人： Takeshi Doi ,  Wei Zhang

发明人： Takeshi Doi ,  Wei Zhang

IPC分类号： G06K9/00 ,  A61B6/04

CPC分类号： G06T7/0012 ,  G06T2207/30068

摘要： A method, system, and related computer program products are provided for processing a medical image of a body part according to a computer-aided detection (CAD) algorithm, the medical image having an image border, the body part comprising imaged tissue appearing inside the image border and outlying tissue not appearing in the medical image, wherein likely anatomical abnormalities in the outlying tissue near the imaged tissue border are detected by the CAD algorithm. In one example, the detected likely abnormalities in the outlying tissue are located within a first distance from the imaged tissue border, wherein the first distance corresponds to a spatial ambit of a neighborhood-based feature computed by the CAD algorithm.

摘要翻译： 提供了一种根据计算机辅助检测（CAD）算法来处理身体部位的医学图像的方法，系统和相关的计算机程序产品，所述医学图像具有图像边界，所述身体部分包括出现在内部的成像组织 图像边界和不存在于医学图像中的外围组织，其中通过CAD算法检测在成像组织边界附近的外围组织中可能的解剖异常。 在一个示例中，所检测到的外围组织中可能的异常位于距成像组织边界的第一距离内，其中第一距离对应于由CAD算法计算的基于邻域的特征的空间范围。

公开(公告)号：US07664799B2

公开(公告)日：2010-02-16

申请号：US11830568

申请日：2007-07-30

申请人： Niloy Mukherjee ,  Amit Ganesh ,  Sujatha Muthulingam ,  Wei Zhang

发明人： Niloy Mukherjee ,  Amit Ganesh ,  Sujatha Muthulingam ,  Wei Zhang

IPC分类号： G06F17/30

CPC分类号： G06F17/30595 ,  G06F9/5005 ,  G06F9/5016 ,  G06F9/526 ,  Y10S707/99956

摘要： A framework for in-memory space management for content management database systems is provided. A per-instance in-memory dispenser is partitioned. An incoming transaction takes a latch on a partition and obtains sufficient block usage to perform and complete the transaction. Generating redo information is decoupled from transaction level processing and, instead, is performed when block requests are loaded into the in-memory dispenser or synced therefrom to a per-instance on-disk structure.

摘要翻译： 提供了内容管理数据库系统的内存空间管理框架。 每个实例的内存分配器被分区。 传入的事务在分区上占用一个锁存器，并获得足够的块使用来执行和完成事务。 生成重做信息与事务级别处理分离，而是将块请求加载到内存分配器中或从其同步到每个实例磁盘结构时执行。

公开(公告)号：US07629375B2

公开(公告)日：2009-12-08

申请号：US11015198

申请日：2004-12-16

申请人： Bing Wang ,  Yong-Kang Zhang ,  Jian Chen ,  Wei Zhang ,  Jiangao Song ,  Ughetta Del Balzo ,  Lesley Brown ,  Sekhar Boddupalli ,  Steven Bobzin ,  Sylvain Gilat ,  Guy Miller

发明人： Bing Wang ,  Yong-Kang Zhang ,  Jian Chen ,  Wei Zhang ,  Jiangao Song ,  Ughetta Del Balzo ,  Lesley Brown ,  Sekhar Boddupalli ,  Steven Bobzin ,  Sylvain Gilat ,  Guy Miller

IPC分类号： A61K31/415 ,  A01N43/56

CPC分类号： C07D213/30 ,  C07C43/23 ,  C07C45/30 ,  C07C45/71 ,  C07C49/737 ,  C07C69/94 ,  C07C205/17 ,  C07C205/20 ,  C07C205/22 ,  C07C205/35 ,  C07C205/57 ,  C07C235/42 ,  C07C255/36 ,  C07C311/29 ,  C07C2603/24 ,  C07D213/53 ,  C07D231/26 ,  C07D277/20 ,  C07D277/24 ,  C07D295/26 ,  C07D311/72 ,  C07F9/4021 ,  C07C47/575

摘要： Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.

摘要翻译： 细胞保护性化合物，其中许多是以具有某些缀合键的取代苯酚为特征的酚类衍生物，可用于治疗某些缺血性或炎症性疾病，包括但不限于中风，心肌梗死，充血性心力衰竭和特征为 炎症或氧化损伤。 它们也可用于制造用于治疗这些病症的药物和化妆品制剂。

公开(公告)号：US07603786B2

公开(公告)日：2009-10-20

申请号：US11906201

申请日：2007-09-29

申请人： Fuxue Zhang ,  Wei Zhang

发明人： Fuxue Zhang ,  Wei Zhang

IPC分类号： G01C9/06

CPC分类号： G01C9/06 ,  H01L41/053 ,  H01L41/0533 ,  H01L41/1132

摘要： The present invention relates to a new piezoelectric quartz level sensor mainly applied in the attitude stabilized and control system of the aircraft, robot, vehicle, ship, oil drilling platform, construction, industrial automation equipment, radar, and satellite, comprising a sensitive element, signal processing circuit, base, outer case and socket. The piezoelectric quartz level sensor transfers the deflection angle of the object to the force exerted on two symmetrical mounted round piezoelectric quartz wafers, and then utilizing the prominent force sensitivity of the piezoelectric quartz, the level attitude parameter of an objected can be detected through the frequency variation due to the force exerted on the two piezoelectric quartz wafers. Therefore, the present invention can satisfy the demand of high stability and resolution, low non-linear degree, quick start time, wide measuring range and operating temperature, good ability to resist shock, and digital output.

摘要翻译： 本发明涉及一种主要应用在飞机，机器人，车辆，船舶，石油钻井平台，建筑，工业自动化设备，雷达和卫星的姿态稳定和控制系统中的新的压电石英液位传感器，包括敏感元件， 信号处理电路，底座，外壳和插座。 压电石英电平传感器将物体的偏转角传递到两个对称安装的圆形压电石英晶片上的力，然后利用压电石英的突出的力灵敏度，可以通过频率检测被测对象的水平姿态参数 由于施加在两个压电石英晶片上的力的变化。 因此，本发明可以满足高稳定性，分辨率，低非线性度，启动时间快，测量范围宽，工作温度高，抗冲击能力强和数字输出的要求。

公开(公告)号：US20090233374A1

公开(公告)日：2009-09-17

申请号：US12110869

申请日：2008-04-28

申请人： Ling Zang ,  Jeffrey Moore ,  Tammene Naddo ,  Wei Zhang

发明人： Ling Zang ,  Jeffrey Moore ,  Tammene Naddo ,  Wei Zhang

IPC分类号： G01N33/00 ,  B29C39/00 ,  G01N21/75

CPC分类号： G01N33/0047 ,  G01N21/6428 ,  G01N27/4141 ,  G01N33/0057 ,  Y10T436/17

摘要： The present invention relates to a class of fluorescent, organic nanofibrils, and particularly the films comprising entangled piling of these nanofibrils exhibiting effective quenching of their fluorescence upon exposure the vapor of explosives. The invention also relates to a sensor and a method for sensing the explosives vapor and other volatile organic compounds, including the explosives taggants through the modulation of the fluorescence of the nanofibril film and the electrical conductivity of the nanofibrils. The invention also relates to a development of synthetic methods, protocols and techniques that leads to production of various arylene-ethynylene macrocycle (AEM) molecules, which consist of a shape-persistent, toroidal scaffold in planar conformation, with minimal ring strain and highly tunable ring sizes (from 0.5 nm to above 10 nm). The invention also relates to an approach to optimization of the one-dimensional molecular arrangement along the long axis of the nanofibril, which provides increased exciton (excited state) migration (via cofacial intermolecular electronic coupling) and charge transport (via pi-electronic delocalization). A combination of long-range exciton migration and efficient charge transport makes the nanofibrils ideal as sensory materials for detecting explosives and other volatile organic compounds through both optical and electrical sensing mechanisms.

摘要翻译： 本发明涉及一类荧光，有机纳米原纤维，特别是涉及这些纳米纤维缠结的薄膜，这些纳米纤维在暴露爆炸物的蒸气时表现出有效的淬灭荧光。 本发明还涉及一种用于通过调节纳米纤维膜的荧光和纳米原纤维的电导率来感测爆炸物蒸汽和其它挥发性有机化合物（包括爆炸物标记物）的传感器和方法。 本发明还涉及导致生产各种亚芳基 - 亚乙炔大环（AEM）分子的合成方法，方案和技术的开发，所述亚芳基 - 亚乙炔大环（AEM）分子由平面构象中的形状持久的环形支架构成，具有最小的环应变和高度可调的 环尺寸（从0.5nm到10nm以上）。 本发明还涉及一种优化沿着纳米纤丝长轴的一维分子排列的方法，该方法提供增加的激子（激发态）迁移（通过共面分子间电子耦合）和电荷传输（通过π电子离域） 。 长距离激子迁移和高效电荷传输的组合使得纳米原纤维理想成为用于通过光学和电学感测机制检测爆炸物和其它挥发性有机化合物的感觉材料。

公开(公告)号：US20090223880A2

公开(公告)日：2009-09-10

申请号：US11922433

申请日：2007-12-18

申请人： Wei Zhang ,  Elke Schulte

发明人： Wei Zhang ,  Elke Schulte

IPC分类号： A61M1/36 ,  A61M1/16 ,  B01D61/30

CPC分类号： A61M1/3639 ,  A61B5/0002 ,  A61B5/021 ,  A61B5/024 ,  A61M1/16 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/3592 ,  A61M2230/06 ,  A61M2230/30

摘要： The invention relates to a dialyser with a measuring unit assigned thereto that transmits data to the dialyser via a wireless link, the measuring unit being able to determine and transmit to the dialyser at least one measurable variable which can also be determined by another measuring device that is connected physically to the dialyser, a comparison of the at least one measurable variable as determined by the measuring unit and by the measuring device indicating whether the measuring unit is indeed the one assigned to the dialyser in question and/or whether the measuring unit is working properly.

摘要翻译： 本发明涉及一种具有分配给其的测量单元的透析器，其经由无线链路将数据发送到透析器，所述测量单元能够确定并向透析器传送至少一个可测量的变量，其也可由另一测量设备确定 物理地与透析器连接，由测量单元确定的至少一个可测量变量与测量设备的比较，指示测量单元是否确实是分配给所述透析器的测量单元和/或测量单元是否为 好好工作。