Process for limiting the penetration into the skin and/or the keratinous fibres of an active cosmetic and/or pharmaceutical agent
    96.
    发明授权
    Process for limiting the penetration into the skin and/or the keratinous fibres of an active cosmetic and/or pharmaceutical agent 失效
    限制活性化妆品和/或药剂对皮肤和/或角质纤维的渗透的方法

    公开(公告)号:US06497888B1

    公开(公告)日:2002-12-24

    申请号:US09689636

    申请日:2000-10-13

    IPC分类号: A61K600

    摘要: A process, composition, and kit for limiting the penetration into the skin and/or the keratinous fibers of at least one cosmetically and/or pharmaceutically active agent present in a base cosmetic and/or pharmaceutical composition for topical application and in particular for reducing the rate of penetration into the skin and/or the keratinous fibers of the active agent(s). The process includes the joint use, with the base composition, of an effective amount of a dispersion of vesicles in a medium, the vesicles comprising at least one ceramide of formula (I): wherein R1 is chosen from saturated and unsaturated, linear and branched C1-C32 alkyl groups optionally substituted by at least one hydroxyl group, wherein said at least one hydroxyl group is optionally esterified by a group chosen from C1-C35 acyls; and R2 is chosen from saturated and unsaturated, linear and branched C1-C50 alkyl groups optionally substituted by at least one hydroxyl groups, and wherein said at least one hydroxyl group is optionally esterified by a group chosen from C1-C30 acyls.

    摘要翻译: 用于限制存在于用于局部应用的基础化妆品和/或药物组合物中的至少一种美容和/或药学活性剂对皮肤和/或角质纤维的渗透的方法,组合物和试剂盒,特别是用于减少 渗透到皮肤和/或活性剂的角质纤维中的速率。 该方法包括与基础组合物共同使用有效量的囊泡在培养基中的分散体,囊泡包含至少一种式(I)的神经酰胺:其中R1选自饱和和不饱和的直链和支链 任选被至少一个羟基取代的C 1 -C 32烷基,其中所述至少一个羟基任选地被选自C 1 -C 35酰基的基团酯化; 并且R 2选自任选被至少一个羟基取代的饱和和不饱和的直链和支链C 1 -C 50烷基,并且其中所述至少一个羟基任选地被选自C 1 -C 30酰基的基团酯化。

    Use of arbutin monoesters as depigmenting agents
    99.
    发明授权
    Use of arbutin monoesters as depigmenting agents 失效
    使用熊果苷单酯作为脱色剂

    公开(公告)号:US06306376B1

    公开(公告)日:2001-10-23

    申请号:US09112001

    申请日:1998-07-08

    申请人: Michel Philippe

    发明人: Michel Philippe

    IPC分类号: A61K3170

    摘要: Arbutin monoesters are employed in a composition for topical application, as a depigmenting and/or bleaching agent for human skin, hair and/or head hair. The invention relates to a method of manufacturing a composition of at least one arbutin monoester in a physiologically acceptable medium for depigmenting and/or bleaching human skin, hair and/or head hair.

    摘要翻译: 熊果苷单酯用于局部施用的组合物中,作为人皮肤,毛发和/或头发的脱色和/或漂白剂。本发明涉及一种在生理上可接受的方法中制备至少一种熊果苷单酯的组合物的方法 用于脱色和/或漂白人类皮肤,头发和/或头发的培养基。