公开(公告)号：US08104166B1

公开(公告)日：2012-01-31

申请号：US10741857

申请日：2003-12-19

申请人： Jinqiu Zhang ,  Ming Zhao ,  Mohamad T. Krounbi ,  Henry Yuan ,  Lien-Chang Wang

发明人： Jinqiu Zhang ,  Ming Zhao ,  Mohamad T. Krounbi ,  Henry Yuan ,  Lien-Chang Wang

IPC分类号： G11B5/127 ,  H04R31/00

CPC分类号： G11B5/3163 ,  B82Y25/00 ,  G01R33/093 ,  G11B5/398 ,  Y10T29/49043 ,  Y10T29/49044 ,  Y10T29/49046 ,  Y10T29/49048 ,  Y10T29/49052

摘要： A method is provided for fabricating a read element with leads that overlay a top surface of a sensor of the read element. The method includes forming a mask over a sensor layer, then using the mask to define the sensor from the sensor layer. The mask is then narrowed and a lead layer is formed that overlays both ends of the top surface of the sensor without covering a center portion of the top surface.

摘要翻译： 提供了一种制造读取元件的方法，该元件具有覆盖读取元件的传感器的顶表面的引线。 该方法包括在传感器层上形成掩模，然后使用掩模从传感器层定义传感器。 然后使掩模变窄，并且形成覆盖传感器顶表面两端的引线层，而不覆盖顶表面的中心部分。

公开(公告)号：US20110195457A1

公开(公告)日：2011-08-11

申请号：US12702884

申请日：2010-02-09

申请人： John Richard Nelson ,  Wei Gao ,  Ming Zhao

发明人： John Richard Nelson ,  Wei Gao ,  Ming Zhao

IPC分类号： C12P19/34 ,  C12N9/12

CPC分类号： C12P19/34 ,  C12Q1/6853 ,  C12Q2525/113 ,  C12Q2525/179 ,  C12Q2563/149 ,  C12Q2565/537 ,  C12Q2531/125

摘要： Methods and kits for amplifying a nucleic acid under isothermal conditions to form an amplified nucleic acid sequence are provided. The methods and kits comprises providing a nucleic acid template, a DNA polymerase, deoxyribonucleoside triphosphates, a primer comprising a randomized sequence, and a specific primer, and amplifying the nucleic acid template.

摘要翻译： 提供了用于在等温条件下扩增核酸以形成扩增的核酸序列的方法和试剂盒。 所述方法和试剂盒包括提供核酸模板，DNA聚合酶，脱氧核糖核苷三磷酸，包含随机序列的引物和特异性引物，并扩增核酸模板。

公开(公告)号：US20110184125A1

公开(公告)日：2011-07-28

申请号：US13119525

申请日：2009-09-22

申请人： Ming Zhao ,  Leo Ternorutsky ,  Patrice Mariucci ,  Victor Xynia Lu

发明人： Ming Zhao ,  Leo Ternorutsky ,  Patrice Mariucci ,  Victor Xynia Lu

IPC分类号： C08L75/16 ,  C08J3/28

CPC分类号： C08G18/724 ,  C08G18/4288 ,  C08G18/6208 ,  C08G18/672 ,  C09J175/16 ,  Y10T428/1462 ,  Y10T428/31551 ,  C08G18/62 ,  C08G18/42 ,  C08G18/40

摘要： The present invention relates to urethane(meth)acrylate resins obtained from the reaction, in a first step, of at least one polyisocyanate (I) with at least one compound (II) containing at least two reactive groups capable to react with isocyanate groups and at least one (meth)acrylate (III) containing essentially one reactive group capable to react with isocyanate groups, and, in a subsequent step, reacting the product obtained from the first step with at least one polyisocyanate (IV) different from the poly-isocyanate (I) used in the first step, and their use for making radiation cured pressure sensitive adhesives.

摘要翻译： 本发明涉及在第一步骤中由至少一种多异氰酸酯（I）与至少一种含有至少两个能够与异氰酸酯基团反应的反应性基团的化合物（II）的反应获得的氨基甲酸酯（甲基）丙烯酸酯树脂，以及 至少一种含有能够与异氰酸酯基团反应的基本上一个反应性基团的（甲基）丙烯酸酯（III），并且在随后的步骤中，将从第一步获得的产物与至少一种不同于聚 - 在第一步中使用的异氰酸酯（I），以及它们用于制造辐射固化的压敏粘合剂的用途。

公开(公告)号：US07700527B2

公开(公告)日：2010-04-20

申请号：US11411618

申请日：2006-04-26

申请人： John Zheng Fang ,  Ming Zhao

发明人： John Zheng Fang ,  Ming Zhao

IPC分类号： C10M145/14

CPC分类号： C10M147/04 ,  C10M2213/04 ,  C10N2230/16 ,  C10N2230/18 ,  C10N2240/04 ,  C10N2240/042

摘要： A composition of matter resistant to foaming comprising a hydrocarbon oil and an acrylate copolymer dispersed in the said hydrocarbon oil, which acrylated copolymer contains at last one polymerised fluorinated (meth)acrylate monomer wherein not more than three neighbouring carbon atoms in the said fluorinated (meth)acrylate monomer carry one or more fluorine substituents.

摘要翻译： 含有分散在烃油中的烃油和丙烯酸酯共聚物的发泡物质的组合物，该丙烯酸酯化共聚物最后含有一种聚合的氟化（甲基）丙烯酸酯单体，其中所述氟化（甲基）丙烯酸酯中不超过三个相邻的碳原子 ）丙烯酸酯单体携带一个或多个氟取代基。

公开(公告)号：US07386933B1

公开(公告)日：2008-06-17

申请号：US11295243

申请日：2005-12-06

申请人： Mohamad T. Krounbi ,  Ming Zhao ,  Yining Hu ,  Jim Watterston

发明人： Mohamad T. Krounbi ,  Ming Zhao ,  Yining Hu ,  Jim Watterston

IPC分类号： G11B5/127 ,  H04R31/00

CPC分类号： B82Y25/00 ,  B82Y10/00 ,  G11B5/3116 ,  G11B5/313 ,  G11B5/3163 ,  G11B5/3967 ,  G11B2005/3996 ,  Y10T29/49043 ,  Y10T29/49044 ,  Y10T29/49046 ,  Y10T29/49048 ,  Y10T29/49052

摘要： A method for fabricating a magnetic recording head writer. The writer includes a bottom magnetic pole and a write gap formed over the bottom pole and a coil trench formed in the bottom pole. A top magnetic pole is provided as two layers with the first layer including front and back tips with spaced apart walls positioned adjacent the trench bottom defining trench sides. A pole cover layer is included that is made up of a thin layer of insulating material deposited to cover sides and bottom of the coil trench. A bottom coil is formed on the pole cover layer in the bottom of the coil trench and coil insulation is provided between coil elements and adjacent trench walls and covemg the coil. A top coil with insulation is formed over the planarized bottom coil insulation and the top pole second layer is formed over the top coil.

摘要翻译： 一种制造磁记录头写入器的方法。 写入器包括形成在底极上的底部磁极和写入间隙以及形成在底部极中的线圈沟槽。 顶部磁极设置为两层，其中第一层包括前部和后部末端，间隔开的壁定位在沟槽底部限定沟槽侧面附近。 包括极覆盖层，其由沉积成覆盖线圈沟槽的侧面和底部的绝缘材料薄层构成。 底线圈形成在线圈沟槽底部的极覆盖层上，线圈绝缘体设置在线圈元件与相邻的沟槽壁之间并且缠绕线圈。 在平坦化的底部线圈绝缘体上形成具有绝缘的顶部线圈，并且顶部第二层形成在顶部线圈上。

公开(公告)号：US07320872B2

公开(公告)日：2008-01-22

申请号：US10183728

申请日：2002-06-27

申请人： Ann Marie Janson ,  Jonas Frisen ,  Clas Johansson ,  Stefan Momma ,  Diana Clarke ,  Ming Zhao ,  Urban Lendahl ,  Kioumars Delfani

发明人： Ann Marie Janson ,  Jonas Frisen ,  Clas Johansson ,  Stefan Momma ,  Diana Clarke ,  Ming Zhao ,  Urban Lendahl ,  Kioumars Delfani

IPC分类号： G01N33/567

CPC分类号： C12N5/0623 ,  A61K35/12

摘要： The invention relates to an ependymal neural CNS stem cell, which cell expresses the surface protein Notch 1 together with at least one surface protein chosen from the group of Notch 2, Notch 3, CAR (transmembrane protein binding adenovirus) and CFTR cystic fibrosis transmembrane conductance regulator), and which cell also comprises at least one cilium. The invention also relates to preparations, including pharmaceutical preparations, comprising ependymal neural CNS stem cells, in vitro and in vivo assays based thereon and various other uses of the novel ependymal cells according to the invention.

摘要翻译： 本发明涉及室管膜神经CNS干细胞，该细胞表达蛋白Notch1以及至少一种选自Notch 2，Notch 3，CAR（跨膜蛋白结合腺病毒）和CFTR囊性纤维化跨膜电导的表面蛋白 调节剂），哪个细胞还包含至少一个纤毛。 本发明还涉及包括室管膜神经CNS干细胞的药物制剂，其中基于其的体外和体内测定法以及根据本发明的新型室管膜细胞的各种其它用途的制剂。

公开(公告)号：US20070248167A1

公开(公告)日：2007-10-25

申请号：US11678929

申请日：2007-02-26

申请人： Jun-Hyun Park ,  Ming Zhao

发明人： Jun-Hyun Park ,  Ming Zhao

IPC分类号： H04N7/12

CPC分类号： H04N19/527 ,  H04N5/145 ,  H04N5/23248

摘要： An image stabilizer includes a motion estimation unit, a motion vector selection unit, a motion compensation vector calculation unit and an image compensation unit. A plurality of divided areas of a picture is projected onto a plurality of windows. The motion estimation unit extracts motion vectors from the plurality of windows. The motion vector selection unit selects an optimal motion vector among the plurality of motion vectors. The motion compensation vector calculation unit calculates a motion compensation vector using the optimal motion vector. The image compensation unit compensates an image of the picture using the motion compensation vector. Accordingly a sudden shift effect may be reduced when stabilizing the image.

摘要翻译： 图像稳定器包括运动估计单元，运动矢量选择单元，运动补偿矢量计算单元和图像补偿单元。 图像的多个分割区域被投影到多个窗口上。 运动估计单元从多个窗口提取运动矢量。 运动矢量选择单元选择多个运动矢量中的最佳运动矢量。 运动补偿矢量计算单元使用最佳运动矢量来计算运动补偿矢量。 图像补偿单元使用运动补偿矢量补偿图像的图像。 因此，当稳定图像时可能会降低突然的移位效果。

公开(公告)号：US07238292B1

公开(公告)日：2007-07-03

申请号：US10909224

申请日：2004-07-30

申请人： Li He ,  Ming Zhao ,  Yining Hu

发明人： Li He ,  Ming Zhao ,  Yining Hu

IPC分类号： B44C1/00 ,  G11B5/127

CPC分类号： G11B5/3163 ,  G11B5/3116 ,  G11B5/3133 ,  G11B5/3136 ,  Y10T29/49025 ,  Y10T29/49041

摘要： A head including a write element for writing data to a magnetic media, and methods for its production are provided. A write element of the invention includes one or more of a recessed first pole, a heat sink layer, and a shortened yoke length. A method of the invention provides forming an anti-reflective layer before forming a mask layer. During photolithography the anti-reflective layer suppresses undesirable reflections off of features, such as vertical sidewalls, that otherwise limit how closely to such features portions of the mask layer can be formed.

摘要翻译： 提供一种包括用于向磁性介质写入数据的写入元件的头，以及用于其生产的方法。 本发明的写入元件包括凹入的第一极，散热层和缩短的磁轭长度中的一个或多个。 本发明的方法提供了在形成掩模层之前形成抗反射层。 在光刻期间，抗反射层抑制了诸如垂直侧壁的特征（例如垂直侧壁）的不期望的反射，否则可以限制与这些特征的接近程度，可以形成掩模层的部分。

公开(公告)号：US20070023643A1

公开(公告)日：2007-02-01

申请号：US11345566

申请日：2006-02-01

申请人： David Nolte ,  Manoj Varma ,  Fred Regnier ,  Leilei Peng ,  Ming Zhao

发明人： David Nolte ,  Manoj Varma ,  Fred Regnier ,  Leilei Peng ,  Ming Zhao

IPC分类号： H01J49/00

CPC分类号： G01N33/54373 ,  G01N21/45 ,  G01N21/553 ,  G01N21/645

摘要： A method of probing a plurality of analyzer molecules distributed about a detection platform is disclosed. The method includes contacting a test sample to the plurality of analyzer molecules, scanning the plurality of analyzer molecules at a rate relating to a carrier frequency signal, and detecting the presence or absence of a biological molecule based at least in part upon the presence or absence of a signal substantially at a sideband of the carrier frequency signal. A molecule detection platform including a substrate and a plurality of targets positioned about the substrate is also disclosed. Specific analyzer molecules adapted to bind a specific analyte are immobilized about a first set of the targets. Nonspecific analyzer molecules are immobilized about a second set of the targets. The targets positioned about the substrate along at least a segment of a scanning pathway alternate between at least one of the first set and at least one of the second set. A method including providing a substrate for supporting biological analyzer molecules the substrate including at least one scanning pathway is also disclosed. The scanning pathway includes a plurality of scanning targets. Specific biological analyzer molecules adapted to detect a specific target analyte are distributed about a first set of the targets which alternate in groups of at least one with a second set of the targets the second set of the targets not including the specific biological analyzer molecules.

摘要翻译： 公开了一种探测分布在检测平台周围的多个分析器分子的方法。 该方法包括使测试样本与多个分析器分子接触，以与载波频率信号相关的速率扫描多个分析器分子，并且至少部分地基于存在或不存在检测生物分子的存在或不存在 基本上在载波频率信号的边带处的信号。 还公开了一种分子检测平台，其包括基板和围绕基板定位的多个靶。 适于结合特定分析物的特异性分析仪分子被固定在第一组靶上。 非特异性分析仪分子被固定在第二组靶上。 沿着扫描通道的至少一段定位在基底周围的靶在第一组和第二组中的至少一个之间交替。 还公开了一种包括提供用于支持生物分析器分子的基板的方法，所述基板包括至少一个扫描路径。 扫描路径包括多个扫描目标。 适于检测特定目标分析物的特异性生物分析仪分子围绕第一组靶标分布，其中至少一组与第二组靶标交替，第二组靶标不包括特定生物分析仪分子。

公开(公告)号：US20070009428A1

公开(公告)日：2007-01-11

申请号：US11175668

申请日：2005-07-06

申请人： Faisal Syud ,  Nichole Wood ,  Andrew Torres ,  Mark Baillie ,  Dinko Trotter ,  Cristina Hehir ,  Ming Zhao ,  Daniel Kramer

发明人： Faisal Syud ,  Nichole Wood ,  Andrew Torres ,  Mark Baillie ,  Dinko Trotter ,  Cristina Hehir ,  Ming Zhao ,  Daniel Kramer

IPC分类号： A61K51/00

CPC分类号： A61K51/04 ,  A61K47/6899 ,  B82Y5/00

摘要： A set of compounds that includes an active-agent labeled species and a pretargeting conjugate is disclosed. The active agent-labeled species includes a ligand coupled to an active agent. The pretargeting conjugate includes a protein conjugated to a targeting species having a targeting moiety capable of binding to an in-vivo target or a biomarker produced by or associated with the target. The protein is substantially free of a cofactor. Also disclosed are methods of administering the pretargeting species and the active-agent labeled species to a subject for diagnosing or treating a disease condition, or assessing the effectiveness of a treatment of the disease condition.

摘要翻译： 公开了一组包含活性剂标记的物质和预靶向缀合物的化合物。 活性剂标记的物质包括与活性剂偶联的配体。 预靶向缀合物包括与靶向物质缀合的蛋白质，其具有能够结合体内靶标的靶向部分或由靶产生或与靶标相关的生物标志物。 蛋白质基本上不含辅因子。 还公开了将预靶向物种和活性剂标记物种施用于受试者以诊断或治疗疾病状况或评估治疗疾病状况的有效性的方法。