摘要:
A sealed self-piercing capsule for storing and delivering a substance, such as a medicine, comprises one or more barrier layers forming a sealed chamber for containing the substance. An internal puncturing mechanism is disposed within the capsule chamber for puncturing a barrier layer to release the substance from the chamber. The internal puncturing mechanism may comprise a sharpened edge located on a movable tube, which moves relative to a barrier layer forming the sealed chamber to puncture the barrier layer.
摘要:
Methods for diagnosing skin lesions are disclosed. Generally, the method include topically administering an IRM compound to a treatment area for a period of time and in an amount effective to cause a visible change in the appearance of a skin lesion including, in some cases, causing subclinical lesions to become visible. Suitable IRM compounds include agonists of one or more TLRs.
摘要:
Methods and apparatus are disclosed that pick up and clean landscape rock using air under vacuum pressure. This apparatus provides a means for cleaning and reusing rock that has become aesthetically unattractive instead of removing the old landscape rock and replacing it with new rock. The invention also includes a device for separating debris from the vacuum airstream. This device may be used in combination with the device for picking up and cleaning landscape rock or may be used independently.
摘要:
A connector apparatus is provided which is configured to replace a separation module in a system for dispensing a fluid. When it is desired to purge the system of a dispensed fluid, the connector apparatus, having the same configuration of an inlet and an outlet as the separation module, replaces the separation module and a purging fluid is passed through the system.
摘要:
Methods of preventing and/or treating UV-induced immunosuppression by administration of immune response modifier compounds are disclosed herein. Suitable immune response modifier compounds include agonists of one or more TLRs.
摘要:
A tire sealer and inflator provides utilization of R-134a propellant combined with a sealant composition. In a described example, a tire sealer and inflator includes R-134a propellant, and a sealant composition consisting essentially of, by weight, water approximately 77%, acrylic resin emulsion approximately 22%, sodium nitrite approximately 0.75%, oleic acid approximately 0.01%, and ammonium hydroxide approximately 0.01%.
摘要:
Immune response modifier (IRM) compounds—imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, thiazolo- and oxazolo-quinolinamines and pyridinamines, imidazonaphthyridine and tetrahydroimidazonaphthyridine amines—are useful for the treatment of conditions at and below the mucosal surfaces by administering a therapeutically effective amount of such compounds to the mucosal surface. Novel pharmaceutical formulations are provided. In one embodiment, the pharmaceutical formulations are advantageous for treatment of cervical conditions such as cervical dysplasias including cervical intraepithelial neoplasias.
摘要:
A disabled persons multiple appliance and window remote control system that allows a disabled person to remotely and automatically operate at least one of at least one appliance and at least one window by merely aiming a remote control at any of the at least one of the at least one appliance and the at least one window regardless of which one of the at least one of the at least one appliance and the at least one window the disabled person desires to operate that includes a programmable infrared remote control and a separate and local control system. The programmable infrared remote control has an infrared transmitter that generates separate infrared signals associated with each of the at least one of the at least one appliance and the at least one window. And, the separate and local control system is associated and in electrical communication with each of the at least one of the at least one appliance and the at least one window and with each other and receives the infrared signal from the programmable infrared remote control, so that the disabled person can remotely and automatically operate the at least one of the at least one appliance and the at least one window by merely aiming the programmable infrared remote control at any the separate and local control system associated with any of the at least one of the at least one appliance and the at least one window regardless of which one of the at least one of the at least one appliance and the at least one window the disabled person desires to operate.
摘要:
A pneumatic tire is disclosed which exhibits a good balance of rolling resistance, skid resistance, wear and handling. The rubber compound of the tread cap of the tire contains minor amounts by weight of finely divided high molecular weight high density polyethylene optionally with additional process oil.
摘要:
An electrical shock proof fiber optic control system is disclosed which provides the equivalent of a multiple contact slide switch in optical form along with a fiber optic decoder/interface. Provision is made for single pole switches and multiple throw switches with any number of switch contacts. A novel proportional controller is also provided which varies the amount of light transmitted to a photo-detector by placing a variable optical density filter in series with the light path at the remote control point. One embodiment uses a sliding filter whose optical density is proportional to the lateral displacement of the filter.