摘要:
A compound represented by formula (1): wherein Y1 to Y4 each independently represent any one of the following groups: in which Rα represents a hydrogen atom or a monovalent hydrocarbon group; P1 to P4 each independently represents a group of atoms necessary for forming a heterocyclic ring together with each Y1 to Y4 and the two carbon atoms adjacent to Y1 to Y4, respectively; P5 and P6 each independently represents a group of atoms necessary for forming a cyclic skeleton together with the carbon atom to which Z1 bonds or Z2 bonds; P1 and P2, P2 and P6, P6 and P4, P4 and P3, P3 and P5, and P5 and P1 may further combine with each other to form a ring; Q1 and Q2 each independently represents a connecting group or a direct binding; and Z1 and Z2 each independently represent any one of the following groups; —NRβ2, —ORβ, —SRβ, —PRβ2 in which Rβ represents a hydrogen atom or a monovalent hydrocarbon group, and when plural Rβs are present, these plural Rβs may be the same or different from each other.
摘要:
Compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, D, R2, R2a, R3, R3a, and Z are as defined herein, are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases
摘要:
This disclosure is directed to fused tetracyclic pyrido[4,3-b]indoles and pyrido[3,4-b]indoles. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.
摘要:
The invention provides derivatives and analogs of triazatetracyclo[7.7.0.01,13.02,7]-hexadeca-2,4,6,10,12-pentaenes, 5,7,11-triazatetracyclo[8.7.0.01,6.012,17]-heptadeca-6,8,12,14,16-pentaenes, pharmaceutical compositions comprising these compounds and methods for treatment of hepatitis C viral infections using these compounds.
摘要:
Provided herein are indole and benzofuran fused isoquinuclidene derivatives. Also provided herein are processes, preferably enantioselective processes, for preparing such derivatives including processes for preparing (−) and (+) noribogaine or a salt thereof, in substantially enantiomerically pure forms.
摘要:
The present invention relates to compounds according to formula (1), a method for producing these compounds and electronic devices, in particular organic electroluminescent devices containing said compounds.
摘要:
The present invention relates to new naphthalene carbodiimide (NTCDI) derivatives, and organic electronic device using the same and especially to an organic solar cell. The new NTCDI derivatives are used as acceptor, electron transport material, and doped electron transport materials.
摘要:
Provided is a compound including residues derived from a compound represented by Formula (1) and a divalent aromatic group, wherein the number of the residues is 2 to 4, the number of the divalent aromatic group is 1 to 3, and the sum of the numbers of the residues and the divalent aromatic group is 3 to 5. In Formula (1), each of Y1 to Y4 represent a group represented by any of the following Formula (2); in the following Formula (2), Rα represents a hydrogen atom or a hydrocarbyl group; each of P1 to P4 represents an atomic group forming a heterocyclic ring containing Y1 to Y4; P5 and P6 represent an atomic group forming an aromatic ring or a heterocyclic ring; Q1 and Q2 represent a linking group or a direct bond; and Z1 and Z2 represent a hydrogen atom or a group represented by any of the following Formula (3); and in the following Formula (3), Rβ represents a hydrogen atom or a hydrocarbyl group.
摘要:
The present invention disclosed a bio-based polymer additive, its preparation process and a biodegradable polymer composition comprising the said bio-based polymer additive for use in manufacturing of biodegradable plastic. The said additive is prepared from the biomass of broken microorganism cell such as microalgae, yeast or other microorganisms. In particular, the bio-based polymer additive is for enhancing rheological properties and/or biodegradability of a polymer. In particular, the additive is for use as a pigment.