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    ANTI-CXCL9, ANTI-CXCL10, ANTI-CXCL11, ANTI-CXCL13, ANTI-CXCR3 AND ANTI-CXCR5 AGENTS FOR INFLAMMATORY DISORDERS
    103.
    发明申请
    ANTI-CXCL9, ANTI-CXCL10, ANTI-CXCL11, ANTI-CXCL13, ANTI-CXCR3 AND ANTI-CXCR5 AGENTS FOR INFLAMMATORY DISORDERS 有权
    ANTI-CXCL9，ANTI-CXCL10，ANTI-CXCL11，ANTI-CXCL13，ANTI-CXCR3和抗CXCR5抗炎药物

    公开(公告)号：US20120264645A1

    公开(公告)日：2012-10-18

    申请号：US13535215

    申请日：2012-06-27

    申请人： James W. Lillard, JR.

    发明人： James W. Lillard, JR.

    IPC分类号： G01N33/566 ,  C40B40/10 ,  C40B30/04 ,  C12Q1/68 ,  G01N21/64

    CPC分类号： C07K16/24 ,  A61K2039/505 ,  C07K16/2866

    摘要： A method for detecting an inflammatory disease in a subject is disclosed. The method comprises the steps of (a) detecting a level of expression of one or more inflammatory disease markers in a biological sample obtained from the subject; and (b) comparing the level of expression of said one or more inflammatory disease markers in the biological sample to a normal level of expression of the one or more inflammatory disease markers, wherein the one or more inflammatory disease markers comprise one or more markers selected from the group consisting of CXCL9, CXCL10, CXCL11, CXCL13, CXCR3 and CXCR5. Also disclosed are a method for monitoring the course of treatment for an inflammatory disease in a subject and a kit for detecting an inflammatory disease in a subject.

    摘要翻译： 公开了一种用于检测受试者的炎性疾病的方法。 该方法包括以下步骤：（a）检测从受试者获得的生物样品中的一种或多种炎性疾病标志物的表达水平; 和（b）将生物样品中所述一种或多种炎性疾病标志物的表达水平与一种或多种炎症性疾病标志物的正常表达水平进行比较，其中所述一种或多种炎症性疾病标志物包括选择的一种或多种标志物 来自CXCL9，CXCL10，CXCL11，CXCL13，CXCR3和CXCR5。 还公开了一种用于监测受试者的炎性疾病的治疗过程的方法和用于检测受试者的炎性疾病的试剂盒。

    METHODS FOR DETERMINATION OF HAPLOTYPE DISSECTION
    104.
    发明申请
    METHODS FOR DETERMINATION OF HAPLOTYPE DISSECTION 有权
    用于确定脂肪分解的方法

    公开(公告)号：US20120208183A1

    公开(公告)日：2012-08-16

    申请号：US13267409

    申请日：2011-10-06

    申请人： Qing Song ,  Li Ma ,  Yan Xiao

    发明人： Qing Song ,  Li Ma ,  Yan Xiao

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6827

    摘要： A method for molecular haplotyping of a subject is disclosed. The method comprises: randomly selecting a set of chromosomes in each of a plurality of lyzed diploid cells of the subject, collecting the selected chromosomes from said plurality of cells into a plurality of sample tubes, wherein each sample tube contains chromosomes selected from one or more cells, genotyping genomic DNA in each sample tube, and determining haplotype of the alleles based on allele nucleotide sequence information and corresponding nucleotide signal intensities from genotyping data. Other methods for molecular haplotyping using single cell lysate or single cell microdissection are also disclosed.

    摘要翻译： 公开了一种受试者的分子单倍型的方法。 该方法包括：在受试者的多个裂解的二倍体细胞的每一个中随机选择一组染色体，将所选择的染色体从所述多个细胞收集到多个样品管中，其中每个样品管含有选自一个或多个 细胞，每个样品管中的基因组DNA的基因分型，以及基于等位基因序列信息和来自基因分型数据的相应核苷酸信号强度确定等位基因的单元型。 还公开了使用单细胞裂解物或单细胞显微切割的分子单倍型的其它方法。

    System and method for chronic illness care
    105.
    发明授权
    System and method for chronic illness care 有权
    慢性病护理系统和方法

    公开(公告)号：US08234131B2

    公开(公告)日：2012-07-31

    申请号：US12502950

    申请日：2009-07-14

    申请人： Elizabeth Ofili ,  Priscilla I. Pemu ,  Alexander Quarshie ,  Priscilla Johnson ,  Laura J. Linn ,  Dipendra Kaur ,  Jacquelyn Ali

    发明人： Elizabeth Ofili ,  Priscilla I. Pemu ,  Alexander Quarshie ,  Priscilla Johnson ,  Laura J. Linn ,  Dipendra Kaur ,  Jacquelyn Ali

    IPC分类号： G06Q100/00 ,  G06Q50/00 ,  A61B5/00 ,  G06F19/00

    CPC分类号： G06F19/3418 ,  G06F19/00 ,  G06F19/3481 ,  G06Q50/22 ,  G06Q50/24

    摘要： In one aspect, the present invention relates to a computerized system programmed for providing care support to at least one patient having at least one chronic illness. In one embodiment, the system includes a medical professional module adapted for receiving, storing, and providing data in communication with at least one medical professional at the point of care, a health coach module adapted for receiving, storing, and providing data in communication with the at least one patient and at least one health coach, a patient module adapted for receiving, storing, and providing data in communication with the at least one patient, and, a public health module adapted for receiving, storing, and providing data in communication with at least one research professional. Each of the medical professional module, health coach module, patient module, and public health module is operatively associated with a corresponding one of the at least one medical professional, at least one health coach, at least one patient, and at least one research professional through a network.

    摘要翻译： 一方面，本发明涉及一种被编程用于向至少一名患有至少一种慢性疾病的患者提供护理支持的计算机化系统。 在一个实施例中，该系统包括医疗专业模块，其适于接收，存储和提供在至少一个医疗专业人员的关心点进行通信的数据;健康教练模块，适于接收，存储和提供与 所述至少一个患者和至少一个健康教练，适于接收，存储和提供与所述至少一个患者通信的数据的患者模块，以及适于接收，存储和提供通信中的数据的公共卫生模块 至少有一位研究专业人士。 每个医疗专业模块，健康教练模块，患者模块和公共健康模块可操作地与所述至少一个医疗专业人员，至少一个健康教练，至少一个患者和至少一个研究专业人员中的相应一个 通过网络。