公开(公告)号：US20060128861A1

公开(公告)日：2006-06-15

申请号：US11292441

申请日：2005-12-02

Applicant: Mark Stewart ,  Emerson Sharpe ,  Benjamin Gamble ,  Steven Stafford ,  Robert Estep ,  James Williams ,  Thomas Clark

Inventor： Mark Stewart ,  Emerson Sharpe ,  Benjamin Gamble ,  Steven Stafford ,  Robert Estep ,  James Williams ,  Thomas Clark

IPC: C08K5/09 ,  C08G63/60

CPC classification number: C08K5/098 ,  C08L67/02 ,  C08L77/00 ,  Y10T428/1352 ,  Y10T428/1383 ,  C08L2666/14

Abstract: A solid concentrate is provided having a combination of a transition metal present in an amount ranging from 1000 to 40,000 ppm (weight by metal) and a polyester polymer present in an amount of at least 40 wt. % based on the weight of the concentrate. Concentrates made with highly modified polyester polymers are easy to compound with transition metals forming less brittle polymer upon melt extrusion. Bottle preforms and oxygen scavenging bottles can be made from these concentrates by combining solid polyester particles, solid polyamide particles, and solid these concentrate particles c into an melt processing zone, forming a melt, and forming an article directly from the melt. The b* color and the L* color and the haze levels of the preforms are improved over the preforms made with liquid carriers instead of solid concentrates. The particles are also advantageously simultaneously dried in a drying zone under conditions effective to at least partially remove moisture from the blend to thereby further improve the b* color and L* color.

Abstract translation: 提供了一种固体浓缩物，其具有的存在量为1000至40,000ppm（金属重量）的过渡金属和以至少40重量％的量存在的聚酯聚合物的组合。 基于浓缩物的重量％。 用高度改性的聚酯聚合物制成的浓缩物易于与熔融挤出时形成较少脆性聚合物的过渡金属复合。 通过将固体聚酯颗粒，固体聚酰胺颗粒和固体这些浓缩颗粒c结合到熔融加工区域中，形成熔体并从熔体直接形成制品，可以从这些浓缩物制备瓶预成型件和除氧瓶。 相对于用液体载体代替固体浓缩物制成的预成型件，预型件的b *颜色和L *颜色和雾度水平得到改善。 在有效地至少部分地从共混物中除去水分的条件下，还可以在干燥区中同时干燥颗粒，从而进一步改善b *颜色和L *颜色。

公开(公告)号：US06995240B1

公开(公告)日：2006-02-07

申请号：US09806955

申请日：1999-10-08

Applicant: Gabriel Stavros Panayi ,  Valerie Mary Corrigall ,  Mark Duncan Bodman-Smith ,  Mark Stewart Fife ,  Jeremy Shaun Lanchbury

Inventor： Gabriel Stavros Panayi ,  Valerie Mary Corrigall ,  Mark Duncan Bodman-Smith ,  Mark Stewart Fife ,  Jeremy Shaun Lanchbury

IPC: C07K14/47 ,  A61K39/00 ,  G01N33/53

CPC classification number: C07K14/47 ,  A61K48/00 ,  Y10S435/81

Abstract: The immunoglobulin heavy chain binding protein BiP(GRP78), or a fragment thereof, provides a reagent for indicating the presence of rheumatoid arthritis (RA). The protein used is a recombinant BiP(GRP78) having a defined sequence. A prognostic and/or diagnostic test for RA may be an ELISA or a Western Blot that utilizes the BiP(GRP78) protein or a fragment thereof. Also disclosed are a method of testing for RA using BiP(GRP78) or a cDNA sequence coding therefor. Further disclosed is a method of treating RA by the BiP(GRP78) protein or corresponding cDNA.

Abstract translation: 免疫球蛋白重链结合蛋白BiP（GRP78）或其片段提供了用于指示类风湿性关节炎（RA）存在的试剂。 使用的蛋白质是具有确定的序列的重组BiP（GRP78）。 RA的预后和/或诊断测试可以是利用BiP（GRP78）蛋白或其片段的ELISA或Western印迹。 还公开了使用BiP（GRP78）或其编码的cDNA序列测试RA的方法。 还公开了通过BiP（GRP78）蛋白或相应的cDNA处理RA的方法。

公开(公告)号：US06970858B1

公开(公告)日：2005-11-29

申请号：US09868682

申请日：1999-02-08

Applicant: Mark Stewart Nichols

Inventor： Mark Stewart Nichols

IPC: G06N5/02 ,  G09B7/04

CPC classification number: G09B7/04 ,  G06N5/022

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system uses an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner. A robust business model provides support for realistic activities and allows a user to experience real-world consequences for their actions and decisions and entails realtime decision-making and synthesis of the educational material. The system is architected around a linked list activity table utilized to manage and control the system.

Abstract translation: 公开了一种系统，其提供基于目标的学习系统，其利用基于规则的专家训练系统来提供认知教育经验。 该系统为用户提供了一个模拟环境，为您提供了理解和最佳解决方案的商机。 注意到错误，并动态呈现补救性教材，以建立用户在业务活动中获得成功所需的必要技能。 该系统使用人造智能引擎，驱动具有同步视频和图形的个性化和动态反馈，用于模拟现实环境和交互。 将多个“正确”答案整合到学习系统中，以允许个人化的学习体验，其中通过系统的导航处于学习者控制的步伐。 强大的商业模式提供对现实活动的支持，并允许用户体验现实世界对其行为和决策的后果，并需要实时决策和综合教材。 系统围绕用于管理和控制系统的链表活动表进行架构。

公开(公告)号：US20050096590A1

公开(公告)日：2005-05-05

申请号：US10697486

申请日：2003-10-30

Applicant: George Gullickson ,  Mark Stewart ,  Joseph Cardinal ,  Harry Puryear ,  Scott Klimek ,  James Skarda ,  Richard Thompson ,  Alan Carlson

Inventor： George Gullickson ,  Mark Stewart ,  Joseph Cardinal ,  Harry Puryear ,  Scott Klimek ,  James Skarda ,  Richard Thompson ,  Alan Carlson

IPC: A61M25/01 ,  A61M31/00

CPC classification number: A61M25/0136

Abstract: A deflection mechanism for selectively inducing a bend in a catheter body includes an elongated deflection wire extending within a deflection lumen of the catheter body and into a handle. A guide track is formed within the handle and a thumb wheel is mounted proximal to the elongated guide track within the handle and supports a pinion gear; the thumb wheel and the pinion gear are adapted to be rotated about a common thumb wheel axis, which extends substantially perpendicular to the longitudinal axis. A rack arm extends obliquely to the longitudinal axis of the handle and includes runners received by the guide track, an attachment point coupling the deflection wire to the rack arm and a linear rack engaging the pinion gear. Rotation of the thumb wheel in a first direction draws the deflection wire proximally through the deflection lumen.

Abstract translation: 用于选择性地诱导导管主体中的弯曲的偏转机构包括在导管主体的偏转腔内延伸并延伸到手柄中的细长偏转线。 引导轨道形成在手柄内，拇指轮安装在手柄内的细长导轨附近，并支撑小齿轮; 拇指轮和小齿轮适于围绕基本上垂直于纵向轴线延伸的公共拇指轮轴旋转。 齿条臂相对于手柄的纵向轴线倾斜地延伸，并且包括由导轨接收的跑道，将偏转线连接到齿条臂的连接点和与小齿轮啮合的直线齿条。 拇指轮在第一方向的旋转将偏转线向近侧拉出通过偏转内腔。

公开(公告)号：US20050010095A1

公开(公告)日：2005-01-13

申请号：US10837947

申请日：2004-05-03

Applicant: Mark Stewart ,  Gary Fiedler ,  Jeffrey Sandstrom

Inventor： Mark Stewart ,  Gary Fiedler ,  Jeffrey Sandstrom

IPC: A61B10/00 ,  A61B10/02 ,  A61B17/00 ,  A61B18/00 ,  A61B18/14 ,  A61B5/04

CPC classification number: A61B18/1492 ,  A61B10/0233 ,  A61B2017/00044 ,  A61B2017/00243 ,  A61B2017/00867 ,  A61B2018/00011 ,  A61B2018/00065 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00375 ,  A61B2018/00404 ,  A61B2018/00898 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2018/1472 ,  A61B2218/002

Abstract: According to the present invention, a catheter having at least one multi-purpose lumen formed through the catheter terminates proximal a relatively complex-shaped distal portion thereof. In one form of this embodiment, the relatively complex-shaped distal portion comprises a looped portion having diagnostic- and/or ablation-type electrodes coupled thereto and an elongated diameter-adjusting member coupled proximal the distal end of the looped portion. The multi-purpose lumen may be used to alternately accommodate a variety of dedicated materials; such as, (i) a guide wire for initial deployment or later repositioning of the catheter, (ii) a volume or flow of a contrast media and the like, (iii) a deployable hollow needle or tube and the like used to biopsy adjacent tissue or dispense a therapeutic agent into a volume of tissue, and (iv) a cooling fluid, such as saline solution and the like dispensed at least during therapeutic tissue ablation procedures.

Abstract translation: 根据本发明，具有通过导管形成的至少一个多用途腔的导管终止于其相对复杂形状的远端部分的近端。 在该实施例的一种形式中，相对复杂形状的远侧部分包括具有耦合到其上的诊断和/或消融型电极的环形部分和在环形部分的远端附近耦合的细长直径调节构件。 多用途腔可用于交替容纳各种专用材料; 例如，（i）用于初始部署或稍后重新定位导管的导丝，（ii）造影剂等的体积或流动，（iii）用于活检相邻的可展开的中空针或管等 组织或将治疗剂分配到一定体积的组织中，和（iv）至少在治疗性组织消融过程期间分配的冷却液，例如盐水溶液等。

公开(公告)号：US06782374B2

公开(公告)日：2004-08-24

申请号：US09219478

申请日：1998-12-22

Applicant: Mark Stewart Nichols

Inventor： Mark Stewart Nichols

IPC: G06F1700

CPC classification number: G09B7/04

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner. A robust business model provides support for realistic activities and allows a user to experience real world consequences for their actions and decisions and entails realtime decision-making and synthesis of the educational material. The system includes tools for analysis and display of a presentation as it is presented.

Abstract translation: 公开了一种系统，其提供基于目标的学习系统，其利用基于规则的专家训练系统来提供认知教育经验。 该系统为用户提供了一个模拟环境，为您提供了理解和最佳解决方案的商机。 注意到错误，并动态呈现补救性教材，以建立用户在业务活动中获得成功所需的必要技能。 该系统利用人造智能引擎，驱动具有同步视频和图形的个性化和动态反馈，用于模拟现实环境和交互。 将多个“正确”答案整合到学习系统中，以允许个人化的学习体验，其中通过系统的导航处于学习者控制的步伐。 强大的商业模式提供对现实活动的支持，并允许用户体验现实世界对他们的行为和决策的后果，并需要实时决策和综合教材。 该系统包括用于分析和显示演示文稿的工具。

公开(公告)号：US06670021B2

公开(公告)日：2003-12-30

申请号：US09683063

申请日：2001-11-14

Applicant: Mark Stewart Schroder ,  Paul Stephen DiMascio ,  Randall Richard Good

Inventor： Mark Stewart Schroder ,  Paul Stephen DiMascio ,  Randall Richard Good

IPC: B32B324

CPC classification number: F16C33/043 ,  Y10T16/05 ,  Y10T16/088 ,  Y10T403/7073 ,  Y10T403/75 ,  Y10T428/24273 ,  Y10T428/24322 ,  Y10T428/24331 ,  Y10T428/24521 ,  Y10T428/249928 ,  Y10T428/292

Abstract: 12A high temperature gas turbine component includes an inner core made of a monolithic ceramic material embedded within an outer CMC shell. The inner core may be formed with a through hole, blind hole, wear pads and the like. A method of making the bushing includes the steps of a) forming an inner core of silicon nitride or silicon carbide; and b) applying a ceramic matrix composite material over substantially all of the inner core.

Abstract translation: 12A高温燃气轮机部件包括由嵌入外部CMC壳体内的整体陶瓷材料制成的内芯。 内芯可以形成有通孔，盲孔，耐磨垫等。 制造衬套的方法包括以下步骤：a）形成氮化硅或碳化硅的内芯; 和b）在基本上所有内核上施加陶瓷基复合材料。

公开(公告)号：US06422807B1

公开(公告)日：2002-07-23

申请号：US09726213

申请日：2000-11-28

Applicant: David Leach ,  Iain Robertson Kellock ,  Larry Wayne Plemmons ,  Cedric Chow ,  Brendan Francis Sexton ,  Mark Stewart Schroder

Inventor： David Leach ,  Iain Robertson Kellock ,  Larry Wayne Plemmons ,  Cedric Chow ,  Brendan Francis Sexton ,  Mark Stewart Schroder

IPC: F01D1124

CPC classification number: F01D25/08 ,  F01D11/24 ,  F01D25/26

Abstract: A method of operating a gas turbine having inner and outer shells, with the inner shell being radially movable relative to rotor bucket tip passage in the inner shell for flowing a thermal medium. A pair of passage portions are formed in each of the aft and forward inner shell sections with axially communicating passageways between the passage portions. A thermal medium, preferably from an off-turbine site, is provided for flow through the second-stage aft inner shell section, along axial passageways along the mid-line of the inner shell to a first passage portion of the forward inner shell section. Cross-over paths flow the thermal medium from the first passage portions to second circumferentially extending passage portions of the forward inner shell section, in turn, in communication with axial passageways extending from the forward section to the aft section. A second pair of passage portions flow the thermal medium to an outlet in the aft section. By controlling the temperature of the thermal medium for flow through the aft and forward sections of the inner shell, the clearance between the shrouds and the tips of the buckets for at least the first and second stages of the turbine is controllably adjusted.

Abstract translation: 一种操作具有内壳和外壳的燃气轮机的方法，其中内壳可相对于内壳中的转子铲斗前端通道径向移动以使热介质流动。 一对通道部分形成在每个前后内壳部分中，在通道部分之间具有轴向连通的通道。 提供优选来自涡轮机外部位置的热介质，用于沿着沿着内壳的中线的轴向通道流到第二级后部内壳部分，以沿着前部内壳部分的第一通道部分流动。 交叉路径将热介质从第一通道部分流动到前内壳部分的第二周向延伸通道部分，然后与从前部延伸到后部的轴向通道连通。 第二对通道部分将热介质流到尾部的出口。 通过控制用于流过内壳的后部和前部的流体的热介质的温度，可控地调节涡轮机的至少第一级和第二级的护罩与铲斗顶端之间的间隙。

公开(公告)号：USD440644S1

公开(公告)日：2001-04-17

申请号：US29121945

申请日：2000-04-17

Applicant: Shailesh V. Potnis ,  Robert Baumann ,  Greg Brandt ,  Brett Tate ,  Mark Stewart

Designer： Shailesh V. Potnis ,  Robert Baumann ,  Greg Brandt ,  Brett Tate ,  Mark Stewart

公开(公告)号：US20250092669A1

公开(公告)日：2025-03-20

申请号：US18368824

申请日：2023-09-15

Applicant: Paul D. Murdock ,  Shawn McNamara ,  Ethan Bay Limon ,  Jonathan Louis Hankenhof ,  Timothy Mark Stewart

Inventor： Paul D. Murdock ,  Shawn McNamara ,  Ethan Bay Limon ,  Jonathan Louis Hankenhof ,  Timothy Mark Stewart

IPC: E04B1/41

Abstract: A system including an attachment device having a body with a hollow, axially oriented core and a radially outwardly extending flange coupled to the core. The body has an opening configured to receive a fastener therethrough, and the core has a plurality of slots formed therein. The core is configured such that at least about 20% of a perimeter of at least one location along a length of the core is defined by the slots.