公开(公告)号：US11904040B2

公开(公告)日：2024-02-20

申请号：US17853862

申请日：2022-06-29

Applicant: Colgate-Palmolive Company

Inventor： Tatiana Brinzari ,  Michael Stranick ,  Chi-Yuan Cheng ,  Zhigang Hao ,  Iraklis Pappas ,  Greggory Marron ,  Viktor Dubovoy ,  Long Pan

IPC: A61K8/44 ,  A61K8/02 ,  A61K8/27 ,  A61K8/46 ,  A61Q11/00

CPC classification number: A61K8/44 ,  A61K8/022 ,  A61K8/27 ,  A61K8/463 ,  A61Q11/00 ,  A61K2800/58 ,  A61K2800/92

Abstract: Described herein are zinc-amino acid-lauryl sulfate complexes and oral care compositions comprising the same; and methods of making and using the same are also described.

公开(公告)号：US11690791B2

公开(公告)日：2023-07-04

申请号：US15539725

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： Shiri Nawrocki ,  Viktor Dubovoy ,  Long Pan ,  Baohua Qiao ,  Gregory Szewczyk ,  Ravi Subramanyam

IPC: A61K8/27 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/365 ,  A61Q15/00

CPC classification number: A61K8/27 ,  A61K8/24 ,  A61K8/365 ,  A61Q11/00 ,  A61Q15/00 ,  A61K2800/92

Abstract: An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including a zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and a solvent, the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.

公开(公告)号：US11278481B2

公开(公告)日：2022-03-22

申请号：US16955308

申请日：2017-12-19

Applicant: Colgate-Palmolive Company

Inventor： Zhigang Hao ,  Chi-Yuan Cheng ,  Long Pan ,  Ravi Subramanyam

IPC: A61K8/43 ,  A61K8/02 ,  A61K8/46 ,  A61Q11/00

Abstract: The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C22H32Cl2N10][C6H12NO3S]2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.

公开(公告)号：US11186489B2

公开(公告)日：2021-11-30

申请号：US16206671

申请日：2018-11-30

Applicant: Colgate-Palmolive Company

Inventor： Viktor Dubovoy ,  Tatiana Brinzari ,  Michael Stranick ,  Long Pan ,  Ravi Subramanyam

IPC: C01B33/18 ,  A61K8/25 ,  A61K8/27 ,  A61K8/44 ,  A61K8/21 ,  A61Q11/00 ,  A61K8/02

Abstract: Disclosed herein is zinc/amino acid functionalized silica, compositions comprising the same, and oral care methods and uses for such compositions.

公开(公告)号：US11110042B2

公开(公告)日：2021-09-07

申请号：US16820909

申请日：2020-03-17

Applicant: Colgate-Palmolive Company

Inventor： Zhigang Hao ,  Paul Thomson ,  Long Pan ,  Tatiana Brinzari ,  Guofeng Xu ,  Sergio Leite ,  Yu Wang

IPC: A61K8/24 ,  A61Q11/00

Abstract: Disclosed herein are improved methods for the synthesis of stannous pyrophosphate, as well as improved methods for the manufacture of oral care compositions comprising stannous pyrophosphate.

公开(公告)号：US11020330B2

公开(公告)日：2021-06-01

申请号：US15539437

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： Baohua Qiao ,  Peter R. Hilliard, Jr. ,  Long Pan ,  Shiri Nawrocki ,  Viktor Dubovoy

IPC: A61K8/27 ,  A61Q15/00 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/55 ,  A61K8/64

Abstract: A personal care composition, comprising a soluble zinc polyphosphate complex made by combining ingredients comprising an organic zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and an aqueous solvent; wherein the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Also, a method of using the composition for reducing at least one of perspiration or body odor.

公开(公告)号：US10792236B2

公开(公告)日：2020-10-06

申请号：US16284668

申请日：2019-02-25

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Shaotang Yuan ,  Shira Pilch ,  James G. Masters ,  Zhiqiang Liu ,  Vyoma Patel

IPC: A61K8/44 ,  A61K8/04 ,  A61K8/73 ,  A61K8/20 ,  A61K8/27 ,  A61K8/21 ,  A61Q11/00

Abstract: Disclosed herein are dentifrices comprising a zinc amino acid halide, which provide a precipitate of zinc oxide upon use with dilution with water and/or saliva. Methods of making and using the dentifrices are also provided.

公开(公告)号：US10768154B2

公开(公告)日：2020-09-08

申请号：US15464643

申请日：2017-03-21

Applicant: Colgate-Palmolive Company

Inventor： Venda Porter Maloney ,  Donghui Wu ,  Long Pan ,  Preston Snee ,  Armen Shamirian

IPC: G01N33/00 ,  C09K11/88 ,  C09K11/02 ,  C09K11/06 ,  C09B11/24 ,  G01N33/84

Abstract: The present disclosure is directed to a sensing agent. The sensing agent comprises a quantum dot; and a dye moiety coupled to the quantum dot. The sensing agent is capable of sensing at least one analyte chosen from hydrogen sulfide (H2S) and bisulfide. Sensors made from the sensing agents are also disclosed.

公开(公告)号：US10709907B2

公开(公告)日：2020-07-14

申请号：US16099718

申请日：2016-05-10

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Jung Seo ,  Zeenat Nabi ,  Shujiang Cheng ,  Nadia Soliman ,  Laurence D. Du-Thumm ,  Diana Scala ,  Kyle Robbins ,  Rahul Patel ,  Marian Holerca

IPC: A61Q15/00 ,  A61K8/97 ,  A61K8/46 ,  A61K8/26 ,  A61K8/28 ,  A61K8/9794 ,  A61P31/04

Abstract: Personal care compositions containing active ingredients and an anti-irritant combination of aloe and taurine are disclosed. Methods of preparing the personal care composition and uses of the personal care composition are also disclosed.

公开(公告)号：US10588841B2

公开(公告)日：2020-03-17

申请号：US16135136

申请日：2018-09-19

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Shaotang Yuan ,  Shira Pilch ,  James Masters ,  Zhiqiang Liu

IPC: A61K8/58 ,  A61K8/20 ,  A61K8/27 ,  A61K8/21 ,  A61K8/44 ,  A61Q11/00

Abstract: Disclosed herein are oral care compositions comprising a zinc amino acid halide. Methods of making and using the compositions are also provided.