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    Method For Delivering A Substance To An Eye
    102.
    发明申请
    Method For Delivering A Substance To An Eye 审中-公开
    向眼睛提供物质的方法

    公开(公告)号：US20100280466A1

    公开(公告)日：2010-11-04

    申请号：US12724370

    申请日：2010-03-15

    Applicant: Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

    Inventor： Daniel Py ,  Julian V. Chan ,  Jeffrey M. Atwood

    IPC: A61M35/00 ,  A61F9/00

    CPC classification number: B05B11/007 ,  A61F9/0008 ,  A61M11/007 ,  A61M15/08 ,  A61M35/003 ,  A61M2210/0612 ,  B05B11/00412 ,  B05B11/00416 ,  B05B11/0056 ,  B05B11/0072 ,  B05B11/3004 ,  B05B11/3056 ,  B05B11/307 ,  B05B11/3074 ,  B05B11/3077

    Abstract: An ophthalmic delivery device includes a body defining a fluid reservoir and a pump in fluid communication with the reservoir. The delivery device also includes a nozzle that includes a dosage chamber for holding a dosage of fluid, a valve seat, and a valve cover. The valve cover extends about the valve seat and forms an interface therebetween and the valve seat includes an outlet aperture. The interface is in fluid communication with the outlet aperture and the dosage chamber, and at least part of the valve cover is movable between (i) a closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The valve seat and the valve cover are dimensioned to dispense the dosage of fluid through the interface at a velocity of equal to or less than 6 meters per second.

    Abstract translation: 眼科输送装置包括限定流体储存器的主体和与储存器流体连通的泵。 输送装置还包括喷嘴，该喷嘴包括用于保持流体用量的剂量室，阀座和阀盖。 阀盖围绕阀座延伸并且在它们之间形成界面，并且阀座包括出口孔。 所述界面与所述出口孔和所述剂量室流体连通，并且所述阀盖的至少一部分可在（i）与所述阀盖接合所述阀座的关闭位置之间移动以关闭所述界面并形成流体密封 密封在其间，和（ii）打开位置，其中阀盖的至少一部分响应于流体以大于阀打开压力的压力流过出口孔而与阀座间隔开，以允许加压流体在其间通过 。 阀座和阀盖的尺寸设计为以等于或小于6米/秒的速度通过界面分配流体的剂量。

    Device with penetrable and resealable portion
    103.
    发明申请
    Device with penetrable and resealable portion 审中-公开
    具有可穿透和可重新密封部分的装置

    公开(公告)号：US20100276035A1

    公开(公告)日：2010-11-04

    申请号：US12837329

    申请日：2010-07-15

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65B3/04

    CPC classification number: A61M5/3129 ,  A61J1/2041 ,  A61J1/2044 ,  A61J1/2055 ,  A61J1/2093 ,  A61M5/1782 ,  A61M5/284 ,  A61M2005/3123

    Abstract: A syringe and a reconstitution syringe are provided for the delivery of controlled doses of any of numerous different sterile substances, such as vaccines, medicaments, pharmaceutical preparations, cosmetics, and food products. A plunger of the syringe defines a resealable stopper frictionally and slidably received within a hollow syringe body for dispensing the medicament or other substance through a dispensing tip of the syringe upon movement of the plunger. The resealable stopper defines a heat-sealable portion to allow the stopper to be penetrated by a needle or other filling device to fill the syringe with a medicament or other substance, and in turn allow the hole remaining upon withdrawal of the needle to be heat sealed by transmission of laser energy thereon. A reconstitution syringe defines within a syringe body plural compartments, wherein each compartment stores a respective component of a multi-component medicament or other preparation.

    Abstract translation: 提供注射器和重组注射器用于递送受控剂量的许多不同的无菌物质，例如疫苗，药物，药物制剂，化妆品和食品中的任何一种。 注射器的柱塞限定了摩擦并可滑动地容纳在中空注射器主体内的可再密封塞子，用于在柱塞移动时通过注射器的分配尖端分配药物或其它物质。 可重新密封的止动件限定了可热封部分，以允许止动器被针或其他填充装置穿透，以用药物或其它物质填充注射器，并且进而允许在针头被热封时提供剩余的孔 通过在其上传输激光能量。 重建注射器在注射器主体内限定多个隔室，其中每个隔室存储多组分药物或其它制剂的相应组分。

    One-way valve and apparatus and method of using the valve
    105.
    发明授权
    One-way valve and apparatus and method of using the valve 有权
    单向阀及其使用方法及阀门

    公开(公告)号：US07810677B2

    公开(公告)日：2010-10-12

    申请号：US11650102

    申请日：2007-01-05

    Applicant: Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

    Inventor： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

    IPC: B65D37/00

    CPC classification number: B67D1/108 ,  B05B11/00444 ,  B65B39/004 ,  B65D51/002 ,  B65D51/1616 ,  B67D1/0004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/0801 ,  B67D1/10 ,  B67D1/1279 ,  B67D3/0067 ,  B67D3/04 ,  B67D2001/0827 ,  F04B53/1037

    Abstract: A flexible pouch defining a variable volume storage chamber and one-way valve assembly for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom in cooperation with a pump, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The one-way valve includes a valve seat and elastic valve cover portion overlying the valve seat forming an interference fit therewith defining a normally-closed seam therebetween. The valve portion is movable radially between (i) a normally closed position with the valve portion engaging the valve seat, and (ii) an open position with at least a segment of the valve portion spaced radially away from the valve seat to allow substance from the storage chamber through the valve opening. The one-way valve maintains substance remaining in the variable-volume storage chamber in an aseptic condition sealed with respect to the ambient atmosphere.

    Abstract translation: 柔性袋，其限定可变体积存储室和用于无菌存储物质的单向阀组件，与泵协作地分配多个储存物质的部分，并将残留在袋中的物质保持在相对于 环境气氛。 单向阀包括阀座和覆盖阀座的弹性阀盖部分，形成过盈配合，从而限定了它们之间的常闭接缝。 阀部分可以在（i）常闭位置之间径向移动，阀部分接合阀座，和（ii）打开位置，其中阀部分的至少一段与阀座径向间隔开，从而允许物质从 储存室通过阀门开口。 单向阀在相对于环境大气密封的无菌状态下保持残留在可变容积储存室中的物质。

    Sealed Containers and Methods of Filing and Resealing Same
    106.
    发明申请
    Sealed Containers and Methods of Filing and Resealing Same 有权
    密封容器及其相同方法

    公开(公告)号：US20100236193A1

    公开(公告)日：2010-09-23

    申请号：US12791629

    申请日：2010-06-01

    Applicant: Daniel Py ,  Norbert M. Assion

    Inventor： Daniel Py ,  Norbert M. Assion

    IPC: B65B3/02 ,  B65B55/08 ,  B65B51/10

    CPC classification number: B65B3/003 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/1425 ,  A61J1/1431 ,  A61J1/1468 ,  A61J1/18 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/2096 ,  A61M2207/00 ,  A61M2209/045 ,  B65B3/027 ,  B65B7/161 ,  B65B51/10 ,  B65B55/08 ,  B65B2039/009 ,  B65D51/002

    Abstract: Disclosed is a container and method for filling same. The container includes a thermally resealable portion that is fusible in response to thermal energy, and a container body having a sealed empty chamber in fluid communication with the resealable portion for receiving therein a substance. The container also includes a base, a mid-portion, and an upper portion axially spaced from the base on an opposite side of the mid-portion relative to the base. Each of the base and upper portion define a laterally-extending dimension greater than a maximum laterally-extending dimension of the mid-portion. The method of filling the container includes penetrating the resealable portion with an injection member and introducing a substance into the chamber, withdrawing the injection member while engaging the base of the body to substantially prevent axial movement of the body, and applying thermal energy to the resealable portion to thermally fuse the penetrated region thereof.

    Abstract translation: 公开了一种容器及其填充方法。 该容器包括能够响应于热能而易熔的可热再密封部分，以及具有密封空腔的容器主体，其与可再密封部分流体连通，用于在其中容纳物质。 容器还包括基部，中间部分和与基部相对于基部在中间部分的相对侧上轴向间隔开的上部。 基部和上部中的每一个限定大于中间部分的最大横向延伸尺寸的横向延伸的尺寸。 填充容器的方法包括用注射构件穿透可重新密封的部分并将物质引入腔室中，在与身体的基部接触的同时取出注射构件，以基本上防止身体的轴向移动，并将热能施加到可重新密封 部分，以热熔融其穿透区域。

    Container and one-way valve assembly for storing and dispensing substances, and related method
    107.
    发明授权
    Container and one-way valve assembly for storing and dispensing substances, and related method 有权
    用于储存和分配物质的容器和单向阀组件及相关方法

    公开(公告)号：US07775398B2

    公开(公告)日：2010-08-17

    申请号：US11588968

    申请日：2006-10-26

    Applicant: Daniel Py ,  Miles J. Flamenbaum ,  Eric E. Hartman ,  Nathaniel Houle

    Inventor： Daniel Py ,  Miles J. Flamenbaum ,  Eric E. Hartman ,  Nathaniel Houle

    IPC: B67D1/00

    CPC classification number: B65D51/227 ,  B65D47/205 ,  B65D2251/0025 ,  B65D2251/0093

    Abstract: A device for storing and dispensing a substance includes a storage chamber for the substance. The container includes a passageway in fluid communication with the storage chamber. The container includes a pierceable wall located on an opposite side of the passageway relative to the storage chamber. The device includes a one-way valve assembly including a piercing portion. At least one of the piercing portion and the pierceable wall is movable relative to the other between a first position wherein the pierceable portion is not piercing the pierceable wall, and a second position wherein the pierceable portion is piercing the pierceable wall allowing the flow of substance from the storage chamber. A removable member is disposed intermediate the valve and the container that prevents movement of at least one of the piercing portion and pierceable wall to the second position until the removable member is removed.

    Abstract translation: 用于存储和分配物质的装置包括用于物质的储存室。 容器包括与储存室流体连通的通道。 容器包括位于通道相对于储存室的相对侧上的可刺穿的壁。 该装置包括一个包括穿刺部分的单向阀组件。 所述穿刺部分和所述可刺穿壁中的至少一个在所述可刺穿部分不穿透所述可刺穿壁的第一位置与所述可刺穿部分穿透所述可刺穿壁之间允许物质流动的第二位置之间相对于另一个可移动 从储存室。 可拆卸构件设置在阀和容器之间，防止至少一个刺穿部分和可刺穿的壁移动到第二位置，直到可移除构件被移除。

    Resealable containers and assemblies for filling and resealing same
    108.
    发明授权
    Resealable containers and assemblies for filling and resealing same 有权
    可重复密封的容器和组件用于填充和重新密封

    公开(公告)号：US07726357B2

    公开(公告)日：2010-06-01

    申请号：US11933272

    申请日：2007-10-31

    Applicant: Daniel Py ,  Norbert M. Assion

    Inventor： Daniel Py ,  Norbert M. Assion

    IPC: B65B1/20 ,  B65D39/00 ,  A61B19/00

    CPC classification number: B65B3/003 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/1425 ,  A61J1/1431 ,  A61J1/1468 ,  A61J1/18 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/2096 ,  A61M2207/00 ,  A61M2209/045 ,  B65B3/027 ,  B65B7/161 ,  B65B51/10 ,  B65B55/08 ,  B65B2039/009 ,  B65D51/002

    Abstract: Disclosed is a uniquely configured medicament vial assembly which includes a storage vial, a stopper member and a securing ring. The vial assembly is configured to improve healthcare worker safety by providing a shielded gripping location to aid in the reduction of accidental needle sticks. The storage vial has a body portion which defines an interior chamber for storing a predetermined medicament and a neck portion through which medicament is received into and withdrawn from the interior chamber. The stopper member is inserted into the mouth of the vial and establishes a first seal. The securing ring is engaged with the mouth of the vial and adapted and configured for retaining the stopper member within the vial mouth and effectuating a second seal. The securing ring is formed from a thermoplastic and/or elastic material. Preferably, the securing ring is formed by molding the thermoplastic and/or elastic material over a portion of the storage vial and stopper member when engaged within the vial mouth.

    Abstract translation: 公开了一种独特构造的药物小瓶组件，其包括存储小瓶，止动构件和固定环。 小瓶组件被配置成通过提供屏蔽夹持位置来帮助减少意外的针棒来改善医护人员的安全性。 存储小瓶具有主体部分，其限定用于存储预定药物的内部腔室和颈部部分，药物通过所述颈部部分容纳到内部腔室中并从内部腔室中排出。 止动件插入小瓶的口中并建立第一密封。 固定环与小瓶的口接合并适于和构造成将止动件保持在小瓶口内并实现第二密封。 固定环由热塑性和/或弹性材料形成。 优选地，固定环通过在接合在小瓶口中时将热塑性和/或弹性材料模制在存储小瓶和止动构件的一部分上而形成。

    CONTAINER AND VALVE ASSEMBLY FOR STORING AND DISPENSING SUBSTANCES, AND RELATED METHOD
    109.
    发明申请
    CONTAINER AND VALVE ASSEMBLY FOR STORING AND DISPENSING SUBSTANCES, AND RELATED METHOD 审中-公开
    用于储存和分配物质的集装箱和阀组件及相关方法

    公开(公告)号：US20100096407A1

    公开(公告)日：2010-04-22

    申请号：US12646307

    申请日：2009-12-23

    Applicant: Daniel Py ,  Julian V. Chan

    Inventor： Daniel Py ,  Julian V. Chan

    IPC: B65D37/00 ,  B65D35/46 ,  B65D25/40

    CPC classification number: B65D35/46 ,  B65D47/205 ,  B65D47/2056 ,  B65D47/2081

    Abstract: A container and valve assembly for storing and dispensing substances including edible substances. The container has a body that has a storage chamber for storing the substance and a head portion for holding the valve assembly. The valve assembly includes a valve body and a valve seat surrounded by a flexible outer cover that includes a valve portion. A seam between the valve portion and valve seat form a one-way release valve wherein a portion of the seam remains closed when the substance is dispensed. To dispense the substance, pressure is applied to the body forcing the substance into the valve assembly, which in turn, controls the flow and release of the substance without exposing the remaining substance to the external atmosphere; thus, the sterility of the storage chamber and remaining substance is maintained, and the shelf life of the substance is increased.

    Abstract translation: 用于储存和分配包括可食用物质的物质的容器和阀组件。 该容器具有一个主体，该主体具有用于储存该物质的储存室和用于保持阀组件的头部。 阀组件包括阀体和由包括阀部分的柔性外盖包围的阀座。 阀部分和阀座之间的接缝形成单向释放阀，其中当物质被分配时，接缝的一部分保持关闭。 为了分配物质，将压力施加到身体，迫使物质进入阀组件，这进而控制物质的流动和释放，而不将剩余物质暴露于外部大气; 因此，保持储存室和剩余物质的不育性，并且物质的保存期限增加。

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