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公开(公告)号:US06277373B1
公开(公告)日:2001-08-21
申请号:US09258643
申请日:1999-02-26
申请人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley , Purvi Shah
发明人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley , Purvi Shah
IPC分类号: A61K3848
摘要: The invention provides a human phosphatidylinositol 4,5-bisphosphate 5-phosphatase (PBPP) and polynucleotides which identify and encode PBPP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PBPP.
摘要翻译: 本发明提供了一种人磷酸肌醇4,5-二磷酸5-磷酸酶(PBPP)和鉴定和编码PBPP的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与PBPP表达相关的疾病的方法。
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公开(公告)号:US6124446A
公开(公告)日:2000-09-26
申请号:US5180
申请日:1998-01-08
申请人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
发明人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
IPC分类号: G01N33/53 , A61K38/00 , A61K38/17 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/566 , G01N33/68 , C07H21/02 , C07H21/04 , C12N1/20
摘要: The invention provides a human Vps35/Mem3-related protein (hvmrp) and polynucleotides which identify and encode hvmrp. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of hvmrp.
摘要翻译: 本发明提供了人Vps35 / Mem3相关蛋白(hvmrp)和鉴定和编码hvmrp的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与hvmrp表达相关的病症的方法。
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公开(公告)号:US6074844A
公开(公告)日:2000-06-13
申请号:US872979
申请日:1997-06-11
申请人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley
发明人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley
CPC分类号: C07K14/705 , C07K14/47 , A61K38/00
摘要: The invention provides two new human membrane fusion proteins (SYTAX1 or SYTAX2) and polynucleotides which identify and encode SYTAX1 or SYTAX2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of SYTAX1 or SYTAX2.
摘要翻译: 本发明提供了两种新的人膜融合蛋白(SYTAX1或SYTAX2)和识别和编码SYTAX1或SYTAX2的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与SYTAX1或SYTAX2表达相关的疾病的方法。
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公开(公告)号:US5994081A
公开(公告)日:1999-11-30
申请号:US067351
申请日:1998-04-27
CPC分类号: C07K14/4741
摘要: The invention provides human keratins (KERT) and polynucleotides which identify and encode KERT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KERT.
摘要翻译: 本发明提供鉴定和编码KERT的人角蛋白(KERT)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与KERT表达相关的障碍的方法。
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公开(公告)号:US5986057A
公开(公告)日:1999-11-16
申请号:US184384
申请日:1998-11-02
申请人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley
发明人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley
摘要: The present invention provides a human vesicle trafficking protein (HVTP) and polynucleotides which identify and encode HVTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing HVTP and for treating or preventing disorders associated with expression of HVTP.
摘要翻译: 本发明提供了人类囊泡运输蛋白(HVTP)和识别和编码HVTP的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 此外,本发明提供了生产HVTP并用于治疗或预防与HVTP表达相关的病症的方法。
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公开(公告)号:US5981263A
公开(公告)日:1999-11-09
申请号:US897443
申请日:1997-07-21
申请人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley , Purvi Shah , Matthew Kaser
发明人: Jennifer L. Hillman , Preeti Lal , Neil C. Corley , Purvi Shah , Matthew Kaser
摘要: The invention provides a human matrilin-3 (MAT-3) and polynucleotides which identify and encode MAT-3. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of MAT-3.
摘要翻译: 本发明提供了人matrilin-3(MAT-3)和识别和编码MAT-3的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与MAT-3表达相关的疾病的方法。
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公开(公告)号:US5968798A
公开(公告)日:1999-10-19
申请号:US911319
申请日:1997-08-14
申请人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
发明人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
CPC分类号: C12N9/0004 , A61K38/00
摘要: The invention provides a human glutaredoxin .beta. (GRX.beta.) and polynucleotides which identify and encode GRX.beta.. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of GRX.beta..
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公开(公告)号:US5965711A
公开(公告)日:1999-10-12
申请号:US213390
申请日:1998-12-15
申请人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
发明人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
IPC分类号: C12N15/09 , A61K31/7088 , A61K38/00 , A61K38/43 , A61K39/395 , A61K45/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/57 , C12Q1/68 , C07K16/00 , C07K1/00
CPC分类号: C12N9/6467
摘要: The present invention provides a human serine protease precursor (HSPP) and polynucleotides which encode HSPP. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HSPP.
摘要翻译: 本发明提供人丝氨酸蛋白酶前体(HSPP)和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,反义分子,抗体或拮抗剂。 本发明还提供了治疗与HSPP表达相关的疾病的方法。
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公开(公告)号:US5942399A
公开(公告)日:1999-08-24
申请号:US73362
申请日:1998-05-06
申请人: Jennifer L. Hillman , Henry Yue , Neil C. Corley
发明人: Jennifer L. Hillman , Henry Yue , Neil C. Corley
CPC分类号: C07K14/705 , A61K38/00
摘要: The invention provides a human amino acid permease homolog (AAPH) and polynucleotides which identify and encode AAPH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of AAPH.
摘要翻译: 本发明提供了人氨基酸通透酶同源物(AAPH)和识别和编码AAPH的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与AAPH表达相关的紊乱的方法。
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公开(公告)号:US5919450A
公开(公告)日:1999-07-06
申请号:US102593
申请日:1998-06-22
申请人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
发明人: Jennifer L. Hillman , Neil C. Corley , Purvi Shah
CPC分类号: C12N9/1088 , C07K14/47 , A61K38/00
摘要: The invention provides a human glutathione S-transferase (GSTH) and polynucleotides which identify and encode GSTH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of GSTH.
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