公开(公告)号：US07999144B2

公开(公告)日：2011-08-16

申请号：US11469847

申请日：2006-09-01

Applicant: Anna Lee Tonkovich ,  Bin Yang ,  Steven T. Perry ,  Terry Mazanec ,  Ravi Arora ,  Francis P. Daly ,  Richard Long ,  Thomas D. Yuschak ,  Paul W. Neagle ,  Amanda Glass

Inventor： Anna Lee Tonkovich ,  Bin Yang ,  Steven T. Perry ,  Terry Mazanec ,  Ravi Arora ,  Francis P. Daly ,  Richard Long ,  Thomas D. Yuschak ,  Paul W. Neagle ,  Amanda Glass

IPC: C07C5/32

CPC classification number: C07C5/48 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00788 ,  B01J2219/00822 ,  B01J2219/00824 ,  B01J2219/00835 ,  B01J2219/0086 ,  B01J2219/00869 ,  B01J2219/00873 ,  B01J2219/00891 ,  B01J2219/00984 ,  C01B3/386 ,  C01B3/50 ,  C01B2203/0261 ,  C01B2203/04 ,  C01B2203/048 ,  C01B2203/1035 ,  C01B2203/1041 ,  C01B2203/1064 ,  C01B2203/107 ,  C01B2203/1247 ,  C07C2523/42 ,  C07C2523/44 ,  C07C2523/52 ,  C07C11/04

Abstract: Methods of oxidative dehydrogenation are described. Surprisingly, Pd and Au alloys of Pt have been discovered to be superior for oxidative dehydrogenation in microchannels. Methods of forming these catalysts via an electroless plating methodology are also described. An apparatus design that minimizes heat transfer to the apparatus' exterior is also described.

Abstract translation: 描述了氧化脱氢方法。 令人惊奇的是，已经发现Pt的Pd和Au合金对于微通道中的氧化脱氢是优越的。 还描述了通过化学镀方法形成这些催化剂的方法。 还描述了最小化到设备外部的热传递的设备设计。

公开(公告)号：US20110133189A1

公开(公告)日：2011-06-09

申请号：US12632351

申请日：2009-12-07

Applicant: Bin Yang ,  Bo Bai

Inventor： Bin Yang ,  Bo Bai

IPC: H01L29/772 ,  H01L21/20

CPC classification number: H01L29/7848 ,  H01L29/165 ,  H01L29/665 ,  H01L29/6656 ,  H01L29/66636 ,  H01L29/7833

Abstract: An NMOS transistor is formed with improved manufacturability. An embodiment includes forming N-type doped embedded silicon germanium containing carbon (eSiGe:C) in source/drain regions of a substrate, and amorphizing the eSiGe:C. The use of eSiGe:C provides a reduction in extension silicon and dopant loss, improved morphology, increased wafer throughput, improved short channel control, and reduced silicide to source/drain contact resistance.

Abstract translation: 形成具有改进的可制造性的NMOS晶体管。 实施例包括在衬底的源极/漏极区域中形成含有N型掺杂的含硅锗（eSiGe：C），并使eSiGe：C非晶化。 eSiGe：C的使用提供了延长硅和掺杂剂损耗的减少，改进的形态，增加的晶片产量，改进的短沟道控制以及降低的硅化物到源/漏接触电阻。

公开(公告)号：US07875444B2

公开(公告)日：2011-01-25

申请号：US11229817

申请日：2005-09-19

Applicant: Bin Yang ,  Charles E. Wyman

Inventor： Bin Yang ,  Charles E. Wyman

IPC: C12P7/06 ,  C12P7/08 ,  C12P7/10 ,  C12P19/14 ,  C12P21/06 ,  C07K14/415 ,  C07K14/765

CPC classification number: C12P7/10 ,  C12P7/08 ,  C12P19/02 ,  Y02E50/16 ,  Y02E50/17

Abstract: Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment enhances cellulase availability in cellulose conversion and allows for the determination of optimized pretreatment conditions. Additionally, ethanol yields from a Simultaneous Saccharification and Fermentation process are improved 5-25% by treatment with a lignin-blocking polypeptide and/or protein. Thus, a more efficient and economical method of processing lignin containing biomass materials utilizes a polypeptide/protein treatment step that effectively blocks lignin binding of cellulase.

Abstract translation: 公开了一种在木质纤维素生物质中转化纤维素的方法。 该方法提供高木质素固体的木质素阻断多肽和/或蛋白质处理。 该处理增强了纤维素转化中的纤维素酶可用性，并且允许确定优化的预处理条件。 此外，通过用木质素阻断多肽和/或蛋白质处理，来自同时糖化和发酵过程的乙醇产率提高了5-25％。 因此，处理含木质素的生物质材料的更有效和经济的方法利用有效阻断木质素结合纤维素酶的多肽/蛋白质处理步骤。

公开(公告)号：US20100248974A1

公开(公告)日：2010-09-30

申请号：US12674150

申请日：2007-10-24

Applicant: Zhinan Chen ,  Ping Zhu ,  Xiaoling Yu ,  Bin Yang ,  Xiangmin Yang ,  Zheng Zhang

Inventor： Zhinan Chen ,  Ping Zhu ,  Xiaoling Yu ,  Bin Yang ,  Xiangmin Yang ,  Zheng Zhang

IPC: C40B30/02 ,  C07K14/00 ,  C07K16/00 ,  C40B30/04 ,  G01N33/566 ,  G06F17/50

CPC classification number: C07K14/70596 ,  C07K2299/00 ,  C30B7/04 ,  C30B29/58 ,  G01N2333/70596 ,  G01N2500/00 ,  G06F19/16 ,  G06F19/706 ,  Y02A90/26

Abstract: A crystal, a preparation method and 3D structure of CD147 extracellular region are provided. Such 3D structure is useful in the determination of the active site of CD147 extracellular region by computer modeling or molecular docking method. The crystal and/or 3D structure are useful in a structure-based drug design and the selection of an antibody, a ligand or an interacting molecule of CD 147 extracellular region.

Abstract translation: 提供了CD147细胞外区域的晶体，制备方法和3D结构。 这种3D结构可用于通过计算机建模或分子对接方法测定CD147细胞外区域的活性位点。 晶体和/或3D结构可用于基于结构的药物设计和CD147细胞外区域的抗体，配体或相互作用分子的选择。

公开(公告)号：US20100068366A1

公开(公告)日：2010-03-18

申请号：US12623780

申请日：2009-11-23

Applicant: Anna Lee Tonkovich ,  Laura J. Silva ,  David John Hesse ,  Michael Alan Marchiando ,  Micheal Jay Lamont ,  Dongming Qiu ,  Terrence Andrew Dritz ,  Kristina M. Pagnotto ,  Richard Stevenson ,  Steven T. Perry ,  Maddalena Fanelli ,  Ravi Arora ,  Bin Yang ,  Sean Patrick Fitzgerald ,  Timothy J. Sullivan ,  Kai Tod Paul Jarosch ,  Thomas Yuschak

Inventor： Anna Lee Tonkovich ,  Laura J. Silva ,  David John Hesse ,  Michael Alan Marchiando ,  Micheal Jay Lamont ,  Dongming Qiu ,  Terrence Andrew Dritz ,  Kristina M. Pagnotto ,  Richard Stevenson ,  Steven T. Perry ,  Maddalena Fanelli ,  Ravi Arora ,  Bin Yang ,  Sean Patrick Fitzgerald ,  Timothy J. Sullivan ,  Kai Tod Paul Jarosch ,  Thomas Yuschak

IPC: C11B5/00 ,  B01F17/00 ,  B01F3/04 ,  D21C9/147 ,  C01B15/01

CPC classification number: B01F3/0446 ,  B01F3/0807 ,  B01F5/0475 ,  B01F5/0476 ,  B01F5/0483 ,  B01F13/0059 ,  B01F15/065 ,  B01F2003/0838 ,  B01F2003/0842 ,  B01F2215/0431 ,  B01F2215/045 ,  B01F2215/0472 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00788 ,  B01J2219/00822 ,  B01J2219/00826 ,  B01J2219/00828 ,  B01J2219/00831 ,  B01J2219/00833 ,  B01J2219/00835 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00889 ,  F28D2021/0052 ,  F28F3/12 ,  F28F2260/02 ,  Y10S516/928 ,  Y10S516/929 ,  Y10T436/2575

Abstract: The disclosed invention relates to a process for making a multiphase mixture, comprising: flowing a first fluid stream through a process microchannel, the first fluid stream comprising at least one liquid and/or at least one gas, the process microchannel having an apertured section; flowing a second fluid stream through the apertured section into the process microchannel in contact with the first fluid stream to form the multiphase mixture, the second fluid stream comprising at least one gas and/or at least one microbody-forming material, the first fluid stream forming a continuous phase in the multiphase mixture, the second fluid stream forming a discontinuous phase dispersed in the continuous phase.

Abstract translation: 所公开的本发明涉及一种制备多相混合物的方法，包括：使第一流体流通过工艺微通道，所述第一流体流包含至少一种液体和/或至少一种气体，所述工艺微通道具有带孔部分; 将第二流体流流过有孔部分进入与第一流体流接触的工艺微通道以形成多相混合物，第二流体流包含至少一种气体和/或至少一种微生物形成材料，第一流体流 在多相混合物中形成连续相，第二流体流形成分散在连续相中的不连续相。

公开(公告)号：US07641865B2

公开(公告)日：2010-01-05

申请号：US11400056

申请日：2006-04-07

Applicant: Anna Lee Tonkovich ,  Bin Yang ,  Steven T. Perry ,  Sean P. Fitzgerald ,  Ravi Arora ,  Robert Luzenski ,  Thomas D. Yuschak

Inventor： Anna Lee Tonkovich ,  Bin Yang ,  Steven T. Perry ,  Sean P. Fitzgerald ,  Ravi Arora ,  Robert Luzenski ,  Thomas D. Yuschak

IPC: B01J10/00

CPC classification number: F28F13/06 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00824 ,  B01J2219/00833 ,  B01J2219/00835 ,  B01J2219/0086 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00995 ,  B01L3/502746 ,  B01L2200/027 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2400/0487 ,  B01L2400/086 ,  F28F2260/02 ,  Y10T137/0396

Abstract: The invention provides apparatuses and techniques for controlling flow between a manifold and two or more connecting microchannels. Flow between plural connecting microchannels, that share a common manifold, can be made more uniform by the use of flow straighteners and distributors that equalize flow in connecting channels. Alternatively, flow can be made more uniform by sections of narrowed diameter within the channels. Methods of making apparatus and methods of conducting unit operations in connecting channels are also described.

Abstract translation: 本发明提供用于控制歧管和两个或更多个连接微通道之间的流动的装置和技术。 通过使用均衡连接通道中的流动的流平衡器和分配器，可以使共享共同歧管的多个连接微通道之间的流动更均匀。 或者，可以通过通道内的变窄直径的部分使流动更均匀。 还描述了在连接通道中进行单元操作的装置和方法的方法。

公开(公告)号：US07498138B2

公开(公告)日：2009-03-03

申请号：US11809953

申请日：2007-06-04

Applicant: Hui Zhang ,  Roger J. Pomerantz ,  Bin Yang

Inventor： Hui Zhang ,  Roger J. Pomerantz ,  Bin Yang

IPC: C12Q1/68

CPC classification number: C07K14/005 ,  A61K38/00 ,  C12N2740/16322 ,  Y10S530/826

Abstract: The HIV-1 protein Vif comprises a multimerization domain that allows Vif-Vif interaction and Vif multimerization, which is important for Vif function in the HIV-1 life-cycle. A method for screening for an antagonist of Vif comprises contacting the multimerization domain of Vif with a test compound that specifically binds the multimerization domain. Antagonists identified by the screening assay inhibit Vif multimerization. The antagonists inhibit essential functions of Vif and accordingly are useful as inhibitors of HIV-1 replication.

Abstract translation: HIV-1蛋白Vif包含允许Vif-Vif相互作用和Vif多聚化的多聚化结构域，这对HIV-1生命周期中的Vif功能是重要的。 用于筛选Vif拮抗剂的方法包括使Vif的多聚化结构域与特异性结合多聚化结构域的测试化合物接触。 通过筛选测定鉴定的拮抗剂抑制Vif多聚化。 拮抗剂抑制Vif的基本功能，因此可用作HIV-1复制的抑制剂。

公开(公告)号：US20090004074A1

公开(公告)日：2009-01-01

申请号：US12157587

申请日：2008-06-11

Applicant: Anna Lee Tonkovich ,  Bin Yang ,  William Allen Rogers, JR. ,  Paul William Neagle ,  Sean P. Fitzgerald ,  Kai Tod Jarosch ,  Dongming Qiu ,  David J. Hesse ,  Micheal Lamont

Inventor： Anna Lee Tonkovich ,  Bin Yang ,  William Allen Rogers, JR. ,  Paul William Neagle ,  Sean P. Fitzgerald ,  Kai Tod Jarosch ,  Dongming Qiu ,  David J. Hesse ,  Micheal Lamont

IPC: B01J12/00

CPC classification number: C01B15/029 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00826 ,  B01J2219/00828 ,  B01J2219/00831 ,  B01J2219/00835 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00907 ,  B01J2219/00918 ,  C01B3/384 ,  C01B15/01 ,  C01B15/027

Abstract: The present invention includes methods and apparatuses that utilize microchannel technology and, more specifically in exemplary form, producing hydrogen peroxide using microchannel technology. An exemplary process for producing hydrogen peroxide comprises flowing feed streams into intimate fluid communication with one another within a process microchannel to form a reactant mixture stream comprising a hydrogen source and an oxygen source such as, without limitation, hydrogen gas and oxygen gas. Thereafter, a catalyst is contacted by the reactant mixture and is operative to convert a majority of the reactant mixture to hydrogen peroxide that is withdrawn via an egressing product stream. During the hydrogen peroxide chemical reaction, exothermic energy is generated. This exothermic energy is absorbed by the fluid within the microchannel as well as the microchannel itself. In a preferred embodiment, a heat exchange fluid is in thermal communication with the microchannel housing the exothermic reaction and is operative to absorb a portion of this exothermic energy and transfer such energy from the microchannel.

Abstract translation: 本发明包括使用微通道技术的方法和装置，更具体地说是在示例性形式中使用微通道技术产生过氧化氢。 用于生产过氧化氢的示例性方法包括使进料流在工艺微通道内相互流体连通，以形成包含氢源和氧源（例如但不限于氢气和氧气）的反应物混合物流。 此后，催化剂被反应物混合物接触并且可操作地将大部分反应物混合物转化成通过出口产物流排出的过氧化氢。 在过氧化氢化学反应过程中，产生放热能。 该放热能被微通道内的流体以及微通道本身所吸收。 在优选实施例中，热交换流体与容纳放热反应的微通道热连通，并且可操作以吸收该放热能量的一部分并从微通道传送这种能量。

公开(公告)号：US20080297853A1

公开(公告)日：2008-12-04

申请号：US12095860

申请日：2006-04-29

Applicant: Bin Yang ,  Wenzhe Shi ,  Wenfa Qi ,  Shengyuan Cheng ,  Lidong Wang

Inventor： Bin Yang ,  Wenzhe Shi ,  Wenfa Qi ,  Shengyuan Cheng ,  Lidong Wang

IPC: G06K15/00

CPC classification number: H04N1/32203 ,  H04N1/32219 ,  H04N1/32352 ,  H04N2201/3205 ,  H04N2201/3208 ,  H04N2201/3214 ,  H04N2201/3221 ,  H04N2201/3266 ,  H04N2201/3281 ,  H04N2201/3284

Abstract: Disclosed are a method and apparatus for embedding or detecting watermarks in a text, which belong to the field of document protection. The method and apparatus overlay an additional layer of shade in a document for recording a large amount of information from watermarks. The shade comprises the dots arranged under certain rules. Shifts of the dots record each bit string within the watermark. According to the method and apparatus, a large amount of information can be embedded and the watermarks embedded in the shade are dispersed together with the document which can be digitized by a scanner for being detected.

Abstract translation: 公开了一种在文本中嵌入或检测水印的方法和装置，它们属于文档保护领域。 该方法和装置在文档中覆盖附加层的阴影以从水印记录大量信息。 阴影包括在某些规则下排列的点。 点的移位记录水印内的每个位串。 根据该方法和装置，可以嵌入大量的信息，并且将嵌入在阴影中的水印与可由扫描器数字化的文档分散在一起以便被检测。

公开(公告)号：US07442360B2

公开(公告)日：2008-10-28

申请号：US11116148

申请日：2005-04-27

Applicant: Anna Lee Y. Tonkovich ,  Bin Yang ,  William Allen Rogers, Jr. ,  Paul William Neagle ,  Sean P. Fitzgerald ,  Kai Tod Paul Jarosch ,  Dongming Qiu ,  David J. Hesse ,  Michael Lamont

Inventor： Anna Lee Y. Tonkovich ,  Bin Yang ,  William Allen Rogers, Jr. ,  Paul William Neagle ,  Sean P. Fitzgerald ,  Kai Tod Paul Jarosch ,  Dongming Qiu ,  David J. Hesse ,  Michael Lamont

IPC: C01B15/029 ,  C01B15/023 ,  C01B15/022

CPC classification number: C01B15/029 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00826 ,  B01J2219/00828 ,  B01J2219/00831 ,  B01J2219/00835 ,  B01J2219/0086 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00907 ,  B01J2219/00918 ,  C01B3/384 ,  C01B15/01 ,  C01B15/027

Abstract: The present invention includes methods and apparatuses that utilize microchannel technology and, more specifically in exemplary form, producing hydrogen peroxide using microchannel technology. An exemplary process for producing hydrogen peroxide comprises flowing feed streams into intimate fluid communication with one another within a process microchannel to form a reactant mixture stream comprising a hydrogen source and an oxygen source such as, without limitation, hydrogen gas and oxygen gas. Thereafter, a catalyst is contacted by the reactant mixture and is operative to convert a majority of the reactant mixture to hydrogen peroxide that is withdrawn via an egressing product stream. During the hydrogen peroxide chemical reaction, exothermic energy is generated. This exothermic energy is absorbed by the fluid within the microchannel as well as the microchannel itself. In a preferred embodiment, a heat exchange fluid is in thermal communication with the microchannel housing the exothermic reaction and is operative to absorb a portion of this exothermic energy and transfer such energy from the microchannel.

Abstract translation: 本发明包括使用微通道技术的方法和装置，更具体地说是在示例性形式中使用微通道技术产生过氧化氢。 用于生产过氧化氢的示例性方法包括使进料流在工艺微通道内相互流体连通以形成包含氢源和氧源（例如但不限于氢气和氧气）的反应物混合物流。 此后，催化剂被反应物混合物接触并且可操作地将大部分反应物混合物转化成通过出口产物流排出的过氧化氢。 在过氧化氢化学反应过程中，产生放热能。 该放热能被微通道内的流体以及微通道本身所吸收。 在优选实施例中，热交换流体与容纳放热反应的微通道热连通，并且可操作以吸收该放热能量的一部分并从微通道传送这种能量。