N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subtype
specific ligands
    101.
    发明授权
    N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subtype specific ligands 失效
    N-氨基烷基二苯并呋喃甲酰胺; 新的多巴胺受体亚型特异性配体

    公开(公告)号:US5710274A

    公开(公告)日:1998-01-20

    申请号:US608259

    申请日:1996-02-28

    申请人: Jun Yuan Xi Chen

    发明人: Jun Yuan Xi Chen

    摘要: Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C.sub.1 -C.sub.6 alkoxy, --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1, or 2; or R.sub.1, R.sub.2, R.sub.3, R.sub.4 independently represent --CONR'.sub.m, or --NR'.sub.m where m is 0, 1 or 2 and R' is hydrogen or C.sub.1 -C.sub.6 alkyl; R.sub.5 is hydrogen or C.sub.1 -C.sub.6 alkyl; and R represents an aminoalkyl group, which compounds are useful in the treatment of affective disorders such as schizophrenia, depression, Alzheimer's disease, movement disorders such as Parkinsonism and dystonia, and other disorders which respond to dopaminergic blockage such as substance abuse and obsessive compulsive disorders. Further, compounds of this invention may be useful in treating the extrapyramidal side effects associated with the use of conventional neuroleptic agents.

    摘要翻译: 公开了下式的化合物或其药学上可接受的酸加成盐,其中:R 1,R 2,R 3,R 4相同或不同,表示氢,C 1 -C 6烷基,卤素,羟基,氨基,氰基 ,硝基,三氟甲基,三氟甲氧基,C 1 -C 6烷氧基,-O 2 CR', - NHCOR', - CON',-SO m R',其中R'是C 1 -C 6烷基,其中m是0,1或2; 或R 1,R 2,R 3,R 4独立地表示-CONR'm或-NR'm,其中m为0,1或2,R'为氢或C 1 -C 6烷基; R5是氢或C1-C6烷基; 并且R代表氨基烷基,该化合物可用于治疗情感障碍如精神分裂症,抑郁症,阿尔茨海默氏病,运动障碍如帕金森综合征和肌张力障碍,以及其他对多巴胺能阻塞作用的疾病,例如药物滥用和强迫症 。 此外,本发明的化合物可用于治疗与使用常规精神抑制剂相关的锥体束外副作用。

    METHODS AND SYSTEMS FOR FEDERATED LEARNING USING FEATURE NORMALIZATION

    公开(公告)号:US20240311645A1

    公开(公告)日:2024-09-19

    申请号:US18182744

    申请日:2023-03-13

    IPC分类号: G06N3/098

    CPC分类号: G06N3/098

    摘要: Methods and systems for federated learning using feature normalization are disclosed. A client implements a local model including at least: a feature extraction subnetwork to extract a feature vector from input data, a normalization layer to normalize the feature vector, and a final layer to generate a prediction output from the normalized feature vector. The local model is initialized using a set of global parameters received from a central server. The local model is updated using data sampled from a local dataset. Information about a state of the updated local model is transmitted to the central server.

    RESEALABLE PACKAGING DEVICE AND METHOD FOR PACKAGING FOOD PRODUCT

    公开(公告)号:US20230079877A1

    公开(公告)日:2023-03-16

    申请号:US17986210

    申请日:2022-11-14

    IPC分类号: B65D75/58 B65D75/36

    摘要: A packaging device incorporating a breathable peel/reseal film and enabling a preservation process for allowing for the distribution, storage and multiple servings of a food product, particularly perishable food product(s), and initiating and controlling the transmission rates, respiration rates or deterioration of the perishable food product(s) and thereby, maintaining good internal and external food quality and normal development of flavor and aroma characteristics. The packaging device includes a plurality of atmospheric control attributes that modulates or controls the atmosphere within the packaging device as the food product(s) respire in order to promote the extended shelf-life of the food product and the maintenance of the quality and desirable marketable characteristics of the food product. The atmospheric control attributes can include perforations that may be positioned in breathable peel/reseal film portion of the package to allow the product respiration for multiple servings without substantially altering the shelf life extension properties of the packaging device.

    COMPOSITIONS FOR OIL RECOVERY AND METHODS OF THEIR USE
    107.
    发明申请
    COMPOSITIONS FOR OIL RECOVERY AND METHODS OF THEIR USE 有权
    用于油料回收的组合物及其使用方法

    公开(公告)号:US20150000909A1

    公开(公告)日:2015-01-01

    申请号:US14478491

    申请日:2014-09-05

    IPC分类号: C09K8/584 E21B43/16

    摘要: Embodiments of the present disclosure include compositions for use in enhanced oil recovery, and methods of using the compositions for recovering oil. Compositions of the present disclosure include a nonionic, non-emulsifying surfactant having a CO2-philicity in a range of about 1.5 to about 5.0, carbon dioxide in a liquid phase or supercritical phase, and water, where the nonionic, non-emulsifying surfactant promotes a formation of a stable foam formed of carbon dioxide and water.

    摘要翻译: 本公开的实施方案包括用于增强油采收的组合物,以及使用该组合物回收油的方法。 本公开的组合物包括在液相或超临界相中的二氧化碳在约1.5至约5.0的范围内的二氧化碳亲和性和非离子,非乳化表面活性剂促进的非离子型非乳化表面活性剂 形成由二氧化碳和水形成的稳定泡沫的形成。

    Shifting register and apparatus for driving gate lines
    108.
    发明授权
    Shifting register and apparatus for driving gate lines 有权
    移位寄存器和驱动门线的装置

    公开(公告)号:US08842061B2

    公开(公告)日:2014-09-23

    申请号:US13439380

    申请日:2012-04-04

    申请人: Xi Chen Wenhai Cui

    发明人: Xi Chen Wenhai Cui

    IPC分类号: G09G3/36 G11C19/28

    摘要: The present invention discloses a shifting register and an apparatus for driving gate lines, and it relates to Liquid Crystal Display technical field, for reducing the noise of a shifting register during non-working period. The shifting register comprises: a first thin film transistor, a second thin film transistor, a third thin film transistor, a fourth thin film transistor, a capacitor and a pull-down module, and the pull-down module is connected among a clock signal port, a first node and a signal output terminal, and further is connected to a low level signal terminal, for maintaining the first node and the signal output terminal to be at low level during the non-working period of the shifting register. The apparatus for driving gate lines comprises a plurality of above shifting registers connected in serial. The present invention is applicable to driving gate lines.

    摘要翻译: 本发明公开了一种用于驱动栅极线的移位寄存器和装置,涉及液晶显示技术领域,用于在非工作期间减少移位寄存器的噪声。 移位寄存器包括:第一薄膜晶体管,第二薄膜晶体管,第三薄膜晶体管,第四薄膜晶体管,电容器和下拉模块,并且下拉模块连接在时钟信号 端口,第一节点和信号输出端子,并且还连接到低电平信号端子,用于在移位寄存器的非工作周期期间将第一节点和信号输出端子保持在低电平。 用于驱动栅极线的装置包括多个串联连接的上述移位寄存器。 本发明适用于驱动栅极线。

    System and methods for finding hidden topics of documents and preference ranking documents

    公开(公告)号:US08521662B2

    公开(公告)日:2013-08-27

    申请号:US13078984

    申请日:2011-04-03

    IPC分类号: G06F15/18

    CPC分类号: G06N99/005 G06F17/30705

    摘要: Systems and methods are disclosed to perform preference learning on a set of documents includes receiving raw input features from the set of documents stored on a data storage device; generating polynomial combinations from the raw input features; generating one or more parameters; applying the parameters to one or more classifiers to generate outputs; determining a loss function and parameter gradients and updating parameters determining one or more sparse regularizing terms and updating the parameters; and expressing that one document is preferred over another in a search query and retrieving one or more documents responsive to the search query.