-
公开(公告)号:US10345548B2
公开(公告)日:2019-07-09
申请号:US14499026
申请日:2014-09-26
发明人: Nezih Dural , Michael V Romalis
摘要: The disclosure provides an optical apparatus including at least one optical element including glass, at least one support including silicon and a housing including glass. Furthermore, the at least one optical element and the at least one support can be anodically bonded together, and the at least one support and the housing can be anodically bonded together. The disclosure further provides a method for fabricating optical components with durable bonds and incorporates active alignment.
-
公开(公告)号:US10344064B2
公开(公告)日:2019-07-09
申请号:US15265321
申请日:2016-09-14
发明人: A. James Link , Siyan Zhang
IPC分类号: A61K38/10 , A61K38/12 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , C07K14/47 , C07K7/08 , A61K38/00 , A61K38/17 , A61K31/635 , G01N33/50 , G01N33/68
摘要: Compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. Pharmaceutical compositions comprising peptide sequences with high cytotoxicity to cancer cell lines are provided. A method for treating cancer is provided.
-
公开(公告)号:US10300410B2
公开(公告)日:2019-05-28
申请号:US14635701
申请日:2015-03-02
发明人: Hantao Ji , Adam Cohen , Phil Efthimion , Eric Edlund , Erik Gilson
摘要: Provided is an advanced liquid centrifuge using differentially rotating cylinders moveable rings at the ends thereof, as well as methods for the separation of fluids, preferably liquids.
-
公开(公告)号:US10300130B2
公开(公告)日:2019-05-28
申请号:US15223980
申请日:2016-07-29
发明人: Thomas Shenk , Dai Wang
IPC分类号: C07K14/11 , A61K39/245 , A61K39/12 , C12N7/00 , A61K39/145 , A61K39/00
摘要: Methods of increasing diversity in cytomegalovirus vaccines through the selection of cell type in which the virus is propagated, and the use of cytomegalovirus produced by those methods in the development of vaccine compositions, are disclosed. Vaccine compositions comprising CMV isolated from epithelial cells are also disclosed.
-
公开(公告)号:US10229068B2
公开(公告)日:2019-03-12
申请号:US15393822
申请日:2016-12-29
申请人: Sameer Wagh , Paul Cuff , Prateek Mittal
发明人: Sameer Wagh , Paul Cuff , Prateek Mittal
摘要: An approach to implementing or configuring an Oblivious RAM (ORAM), which in addition to behaving as a RAM, provides a way to meet a specified degree of privacy in a manner that avoids applying unnecessary computation resources (computation time and/or storages space and/or data transfer) to achieve the specified degree of privacy. In this way, a tradeoff between privacy and computation resources may be tuned to address requirements of a particular application. This ability to tune this tradeoff is not found in other ORAM implementations, which in general aim to achieve complete privacy. In some implementations, the ORAM provides a constant bandwidth overhead compared to conventional RAMs, while achieving a statistical privacy as desired by the user.
-
106.
公开(公告)号:US10215845B2
公开(公告)日:2019-02-26
申请号:US15151812
申请日:2016-05-11
申请人: Andreas Hangauer , Gerard Wysocki
发明人: Andreas Hangauer , Gerard Wysocki
摘要: A system for simultaneous optical pathlength determination and remote chemical sensing of a sample disposed along an optical path. A modulated laser source configured for modulated light emission so that at least one spectral sideband with a sideband frequency is created, the modulated light emission is directed along the optical path and sideband frequency is varied over time. A detector is configured to detect transmitted light along the optical path and generate a detected light intensity signal. A frequency down-converter is configured to receive the detected light emission signal and generate a frequency down-converted light intensity signal. A demodulator is configured to demodulate the frequency of the down-converted light intensity signal and output an instantaneous frequency. A pathlength calculator is configured to determine an optical pathlength to the sample based on the instantaneous frequency. A frequency down-converted light intensity signal is simultaneously output for spectroscopic chemical sensing.
-
公开(公告)号:US10162138B2
公开(公告)日:2018-12-25
申请号:US15259278
申请日:2016-09-08
发明人: Michael G. Gomez , Cara A. Bagley , Benjamin J. Tobias , Ali Zolfaghari , Alexandros Gerakis , Mary Angelique Demetillo
摘要: Disclosed is a self-aligning mirror device for transmission line offset correction. The disclosed self-aligning mechanism automatically adjusts deflectors to couple radiation between two or more offset waveguides or optical fibers.
-
公开(公告)号:US20180356476A1
公开(公告)日:2018-12-13
申请号:US15780322
申请日:2016-12-01
发明人: Michael ROMALIS , Haifeng DONG , Andrei BARANGA
IPC分类号: G01R33/26
CPC分类号: G01R33/26 , G01R33/02 , G01R33/032
摘要: Disclosed is a method and apparatus relating generally to scalar atomic magnetometers. The disclosed methods and apparatus utilize a pressurized sample chamber and a high frequency pulsed pump laser to increase spin polarization and significantly suppress heading errors. These methods and apparatus may also include alternating polarization of the pump light between pulses.
-
109.
公开(公告)号:US20180349142A1
公开(公告)日:2018-12-06
申请号:US15614081
申请日:2017-06-05
发明人: Hongyang Jia , Naveen Verma
摘要: A heterogeneous microprocessor configured to perform classification on an input signal. The heterogeneous microprocessor includes a die with a central processing unit (CPU) a programmable feature-extraction accelerator (FEA) and a classifier. The FEA is configured to perform feature extraction on the input signal to generate feature data. The classifier is configured to perform classification on the feature data and the CPU is configured to provide processing after classification. The FEA may be configured with a plurality of Gene-Computation (GC) Cores. The FEA may be configured for genetic programing with gene depth constraints, gene number constraints and base function constraints. The classifier may be a support-vector machine accelerator (SVMA). The SVMA may include training data based on error-affected feature data. The heterogeneous microprocessor may also include an automatic-programming & classifier training module. An automatic-programming & classifier training module may be configured to receive input-output feature data and training labels and generate gene code and a classifier model.
-
公开(公告)号:US20180221509A1
公开(公告)日:2018-08-09
申请号:US15885591
申请日:2018-01-31
IPC分类号: A61K47/69 , B82Y5/00 , A61Q17/04 , A61K8/85 , A61K47/22 , A61K45/06 , A61K9/51 , A61K47/54 , A61K47/59 , A61K47/55
CPC分类号: A61K47/6931 , A61K8/85 , A61K9/5153 , A61K45/06 , A61K47/22 , A61K47/54 , A61K47/543 , A61K47/545 , A61K47/55 , A61K47/551 , A61K47/552 , A61K47/58 , A61K47/59 , A61K47/593 , A61K47/60 , A61K47/6935 , A61K2800/57 , A61Q17/04 , B82Y5/00
摘要: Particulate constructs stabilized by amphiphilic copolymers and comprising at least one active coupled to a hydrophobic moiety provide sustained release of the active in both in vitro and in vivo environments.
-
-
-
-
-
-
-
-
-