公开(公告)号：US11005023B2

公开(公告)日：2021-05-11

申请号：US16641235

申请日：2018-08-23

Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE ,  UNIVERSIDAD DEL PAÍS VASCO (UPV)

Inventor： Francesco Giazotto ,  Elia Strambini ,  Giorgio De Simoni ,  F. Sebastian Bergeret Sbarbaro

IPC: G11C11/44 ,  H01L39/22 ,  G11C11/16 ,  H01L39/12 ,  H03K19/195

Abstract: A superconducting logic element includes a superconducting tunnel junction including first and second superconductors. First and second insulating ferromagnets in contact with the first and second superconductors, respectively, generate by magnetic proximity effect a predetermined density of spin-split states in the first and second superconductors, respectively. A writing element applies a writing current to at least a superconductor and is in contact with one of the first or second insulating ferromagnets, so that the first and second insulating ferromagnets commute, by the magnetic field generated by the applied writing current, between a state with parallel magnetization to a state with antiparallel magnetization with respect to each other. The superconducting tunnel junction includes the first or second superconductor between which an insulating layer is arranged with tunnel barrier function, the insulating layer selected between a layer selected from the group consisting of AlOx, AlN, and the first or second insulating ferromagnet.

公开(公告)号：US20210103163A1

公开(公告)日：2021-04-08

申请号：US17037933

申请日：2020-09-30

Applicant: Consiglio Nazionale delle Ricerche

Inventor： Simone ZANOTTO ,  Alessandro PITANTI

IPC: G02F1/01

Abstract: This specification discusses a device which modulates, simultaneously or independently, the amplitude, polarization and phase of the electromagnetic radiation. This device has multiple metasurfaces, a spacer region between the metasurfaces, and an actuator for applying a force to at lease one of the metasurfaces. The application of the force changes distance between at least two of the metasurfaces creating the tunability of the electromagnetic radiation.

公开(公告)号：US10933384B2

公开(公告)日：2021-03-02

申请号：US16075879

申请日：2017-02-09

Applicant: Consiglio Nazionale Delle Ricerche

Inventor： Francesca Cunsolo ,  Tommaso Mecca ,  Rita La Spina ,  Fabiola Spitaleri

IPC: B01D71/40 ,  B01J20/26 ,  C08F220/20 ,  B01J20/28 ,  B01D61/24 ,  B01D71/08 ,  C08J3/075 ,  C08K3/16 ,  C08K3/26 ,  C08K5/09 ,  C08K5/10 ,  C08K5/20 ,  C08L5/10 ,  C08L33/14

Abstract: The object of the present invention is a new cryopolymerization process that provides crosslinked polymeric materials in the form of a macroporous gel (cryogel) capable of sequestering (neutralize) the anticoagulant heparin, its low molecular weight derivatives (LMWH and ULMWH) and heparinoids, from aqueous solutions, physiological solutions and biological fluids, such as whole blood, serum and plasma.
A further object of the invention are also crosslinked polymeric materials in the form of a macroporous gel (cryogel) obtained by the cryopolymerization process of the invention that, thanks to said specific process, result to be comprised of varying proportions of HEMA and HEMA-R monomers. The molar ratio between the components (HEMA/HEMA-R) may vary between 99.9% HEMA:0.1% HEMA-R and 0.1% HEMA:99.9% HEMA-R.
Object of the invention is also the use of crosslinked polymeric materials in the form of a macroporous gel (cryogel) obtainable by the cryopolymerization process of the invention for the construction of filters, membranes or devices for the treatment of biological fluids.
A further object of the invention are therefore filters, membranes, or devices for the treatment of biological fluids which comprise materials obtained by the cryopolymerization process of the invention.

公开(公告)号：US20210047380A1

公开(公告)日：2021-02-18

申请号：US16978401

申请日：2019-03-05

Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE

Inventor： Luigi MANNI ,  Marzia SOLIGO ,  Luisa BRACCI-LAUDIERO

IPC: C07K14/48 ,  A61K38/00 ,  A61P25/28

Abstract: A neurotrophic peptide for use as a medicament in the therapeutic treatment of neurodegenerative and/or inflammatory diseases is described. A pharmaceutical composition including the neurotrophic peptide in a pharmaceutically acceptable carrier, as well as in combination with optional adjuvants, stabilizers and/or preservatives, is also described.

公开(公告)号：US20210036210A1

公开(公告)日：2021-02-04

申请号：US17047669

申请日：2019-04-11

Applicant: Consiglio Nazionale Delle Ricerche ,  ENEA - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE ,  Université Grenoble Alpes

Inventor： Riccardo Castagna ,  Massimo Rippa ,  Lucia Petti ,  Anna De Girolamo Del Mauro ,  Giuseppe Nenna ,  Claudia Diletto ,  Gustavo Ardila Rodriguez

IPC: H01L41/08 ,  H01L41/193 ,  H01L41/047 ,  H01L41/297 ,  H01L41/37 ,  H01L41/45 ,  H01L41/314

Abstract: The present invention relates to a energy conversion device (100) configured to convert a light signal into an electrical signal, comprising: an actuator element (50), substantially planar, having at least one activatable portion (30), said activatable portion comprising a photomobile polymeric material; a transducer element (60), substantially planar, having at least a portion of piezoelectric material; wherein said actuator element (50) is coupled to said transducer element (60) so that, at a light beam incident on said photomobile polymeric material, a movement of said transducer element (60) is activated through a movement of said activatable portion (30), said movement of said transducer element (60) providing the generation of a potential difference at the terminal ends of said portion of piezoelectric material.
The present invention also relates to a method of production of the aforesaid device.

公开(公告)号：US10813856B2

公开(公告)日：2020-10-27

申请号：US16082991

申请日：2017-03-06

Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE

Inventor： Anna Tampieri ,  Monica Sandri ,  Simone Sprio

IPC: A61K8/24 ,  A61K8/29 ,  A61Q17/04 ,  A61K8/19 ,  C01B25/32 ,  A61K8/02 ,  A61K8/65 ,  A61K8/73 ,  A61K8/85 ,  A61K8/86

Abstract: The present invention relates to a composition for the protection against solar radiation, consisting of an organic matrix, preferably a gelatin, and hydroxyapatite nanoparticles modified by the substitution of part of the phosphorus with titanium, and part of the calcium with iron.

公开(公告)号：US20200331784A1

公开(公告)日：2020-10-22

申请号：US16763313

申请日：2018-11-16

Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE ,  CISA S.p.A.

Inventor： Claudio Di Iaconi ,  Marco De Sanctis ,  Lorenzo Ferrara

IPC: C02F3/12 ,  C02F3/06 ,  C02F3/10

Abstract: A urban waste water treatment plant, comprising: a tank subdivided in at least two distinct portions, said at least two distinct portions comprising at least an accumulation area of the sludge and at least an accumulation area of the liquid phase; at least a feeding pipe of the waste water to be treated; at least a recirculation pipe of the liquid phase; at least a discharge pipe of the effluent treated, withdrawn from at least one area of the liquid phase, characterized in that said feeding pipe of the waste water to be treated is configured so that the waste water is inlet on the bottom of said at least one sludge area and in discontinuous mode; inside said at least one sludge area it is provided porous material, contained between two containment planes, configured to allow the filtration of the waste water with removal of the suspended material.

公开(公告)号：US10729660B2

公开(公告)日：2020-08-04

申请号：US15538663

申请日：2015-12-22

Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE ,  ISTITUTO NAZIONALE ASSICURAZIONE CONTRO GLI INFORTUNI SUL LAVORO

Inventor： Daniele Catalucci ,  Michele Miragoli ,  Michele Iafisco ,  Anna Tampieri

IPC: A61K9/51 ,  A61K9/14 ,  A61K47/69 ,  A61K47/52 ,  A61K9/00 ,  A61K31/7105 ,  A61K38/03 ,  C12N15/113

Abstract: The invention relates to a process for the preparation of a product comprising one or more nanoparticles of calcium phosphate (CaP-NP) with negative surface charge having a ζ-potential in the range from −41.0 mV to −27.0 mV comprising the steps of: a) maintaining a mixture having a pH in the range from 7 to 10 and comprising an aqueous solution of calcium, an aqueous solution of phosphate and a solution of citrate ions at a temperature in the range from 20° C. to 40° C. for a time in the range from 30 seconds to 10 minutes; b) removing non-reacted ions from the solution of step a), thus obtaining a suspension of one or more nanoparticles of calcium phosphate (CaP-NP); c) recovering the product of one or more nanoparticles of calcium phosphate (CaP-NP) from the suspension of step b). In an advantageous embodiment, the process of the invention provides, in the mixture of step a), also an aqueous solution of one or more therapeutic/diagnostic compounds. The product of the invention may be used as a vehicle for one or more diagnostic/therapeutic compounds for the treatment of cardiovascular diseases through inhalation administration.

公开(公告)号：US20200227617A1

公开(公告)日：2020-07-16

申请号：US16641235

申请日：2018-08-23

Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE ,  CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) ,  UNIVERSIDAD DEL PAÍS VASCO (UPV)

Inventor： Francesco GIAZOTTO ,  Elia STRAMBINI ,  Giorgio DE SIMONI ,  F. Sebastian BERGERET SBARBARO

IPC: H01L39/22 ,  G11C11/44 ,  G11C11/16 ,  H03K19/195 ,  H01L39/12

Abstract: A superconducting logic element includes a superconducting tunnel junction including first and second superconductors. First and second insulating ferromagnets in contact with the first and second superconductors, respectively, generate by magnetic proximity effect a predetermined density of spin-split states in the first and second superconductors, respectively. A writing element applies a writing current to at least a superconductor and is in contact with one of the first or second insulating ferromagnets, so that the first and second insulating ferromagnets commute, by the magnetic field generated by the applied writing current, between a state with parallel magnetization to a state with antiparallel magnetization with respect to each other. The superconducting tunnel junction includes the first or second superconductor between which an insulating layer is arranged with tunnel barrier function, the insulating layer selected between a layer selected from the group consisting of AlOx, AlN, and the first or second insulating ferromagnet.

公开(公告)号：US10571398B2

公开(公告)日：2020-02-25

申请号：US15566543

申请日：2016-04-13

Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE

Inventor： Mario Agio ,  Costanza Toninelli ,  Simona Checcucci ,  Fabrizio Sgrignuoli ,  Sahrish Rizvi ,  Pietro Ernesto Lombardi

IPC: G01N21/64 ,  B82Y20/00

Abstract: The present invention concerns a device constituted by a planar optical antenna which allows to beam and collect light emitted from various light sources, including light-emitting devices (LEDs), fluorescent markers and single-photon sources. By considering the light source as a light receiver and using reciprocity, the device can also be used to improve the absorption of light by various receivers, including molecules. This device is in particular suitable for in-vitro diagnostics (IVD).