公开(公告)号：US20170311904A1

公开(公告)日：2017-11-02

申请号：US15582467

申请日：2017-04-28

申请人： DexCom, Inc.

发明人： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea J. Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC分类号： A61B5/00 ,  G08B21/04 ,  G06N99/00 ,  G06F19/00 ,  A61B5/16 ,  A61B5/145 ,  H04M1/725 ,  G06N5/04

CPC分类号： A61B5/746 ,  A61B5/0022 ,  A61B5/024 ,  A61B5/1112 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/165 ,  A61B5/4866 ,  A61B5/742 ,  A61M5/1723 ,  A61M2205/18 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/8206 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3468 ,  G06N5/043 ,  G06N99/005 ,  G08B21/0453 ,  G16H20/17 ,  G16H40/67 ,  G16H50/20 ,  H04M1/7253 ,  Y02A90/26

摘要： Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US20170261491A1

公开(公告)日：2017-09-14

申请号：US15606954

申请日：2017-05-26

申请人： DexCom, Inc.

发明人： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC分类号： G01N33/487 ,  G06F19/00 ,  G01M99/00

CPC分类号： G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G06F19/70 ,  G06F19/708

摘要： Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

公开(公告)号：US20170188907A1

公开(公告)日：2017-07-06

申请号：US15394658

申请日：2016-12-29

申请人： DexCom, Inc.

发明人： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC分类号： A61B5/1495 ,  A61B5/145

CPC分类号： A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  G01N33/66

摘要： Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US20170071512A1

公开(公告)日：2017-03-16

申请号：US15261818

申请日：2016-09-09

申请人： DexCom, Inc.

发明人： Arturo Garcia ,  Peter C. Simpson ,  Apurv Ullas Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC分类号： A61B5/1495 ,  A61B5/00 ,  A61B5/145

CPC分类号： A61B5/0031 ,  A61B5/1118 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7246 ,  A61B5/743 ,  A61B2560/0223 ,  A61B2560/0228

摘要： Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

摘要翻译： 提供了系统和方法来校准生物系统内的分析物浓度传感器，通常仅使用来自分析物浓度传感器的信号。 例如，在稳定状态下，生物系统内的分析物浓度值是已知的，并且相同的可以提供用于校准的源。 慢移平均值也可采用类似的技术。 公开了变化。

公开(公告)号：US20160106350A1

公开(公告)日：2016-04-21

申请号：US14975444

申请日：2015-12-18

申请人： DexCom, Inc.

发明人： Naresh C. Bhavaraju ,  Michael A. Bloom ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Katherine Yerre Koehler ,  Hari Hampapuram ,  Lauren Hruby Jepson ,  Jonathan Hughes ,  Apurv Ullas Kamath ,  Anna Leigh Rack-Gomer ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC分类号： A61B5/145 ,  A61M5/172 ,  A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/6898 ,  A61B5/72 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/7435 ,  A61B5/746 ,  A61B5/7475 ,  A61B2560/0223 ,  A61B2560/0487 ,  A61M5/1723 ,  A61M2230/005 ,  A61M2230/201 ,  G16H40/40 ,  G16H40/63 ,  Y02A90/26

摘要： Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

摘要翻译： 所描述的系统和方法提供了动态和智能的方式，以便在监视设备的使用过程中改变所需的用户交互级别。 系统和方法通常涉及用户交互的第一或初始模式与第二或新的用户交互模式之间的实时切换。 在某些情况下，切换将对用户自动和透明，在其他情况下，可能会发生用户通知。 模式切换通常影响用户与设备的交互，而不仅仅是内部处理。 模式切换可以涉及校准模式，数据传输模式，控制模式等。

公开(公告)号：US20150351672A1

公开(公告)日：2015-12-10

申请号：US14717965

申请日：2015-05-20

申请人： DexCom, Inc.

发明人： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC分类号： A61B5/1495 ,  A61B5/01 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/053 ,  A61B5/00 ,  A61B5/11

CPC分类号： A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

摘要： Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20150351671A1

公开(公告)日：2015-12-10

申请号：US14717904

申请日：2015-05-20

申请人： DexCom, Inc.

发明人： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC分类号： A61B5/1495 ,  A61B5/145 ,  A61M5/172 ,  A61B5/053 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/01

CPC分类号： A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

摘要： Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20150289821A1

公开(公告)日：2015-10-15

申请号：US14659263

申请日：2015-03-16

申请人： DexCom, Inc.

发明人： Anna Leigh Rack-Gomer ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Eli Reihman ,  Leif N. Bowman ,  Arturo Garcia ,  Katherine Yerre Grubstein ,  Naresh C. Bhavaraju ,  Rian Draeger ,  Paul Kramer ,  Paul Noble-Campbell

IPC分类号： A61B5/00 ,  A61B5/11 ,  A61B5/01 ,  A61B5/145 ,  A61B5/16

CPC分类号： A61B5/7282 ,  A61B5/01 ,  A61B5/1112 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/165 ,  A61B5/168 ,  A61B5/4306 ,  A61B5/4839 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7239 ,  A61B5/7275 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/743 ,  A61B5/7435 ,  A61B5/746 ,  A61B5/7475 ,  A61B2505/07 ,  A61B2560/0295 ,  A61B2560/0475 ,  A61M5/1723 ,  A61M5/5086 ,  A61M2005/1726 ,  G06F3/04817 ,  G06F3/04847 ,  G06F19/3468 ,  G16H40/63

摘要： Systems and methods are disclosed that employ several or numerous factors in the determination of a glycemic urgency index (GUI), which may be based on a measured blood glucose level as well as other factors. The other factors may include time derivatives of the glucose level and/or other factors, e.g., user—entered data, data measured by other sensors or received from a network source, or historical data. The GUI is then presented to the user in an interesting way, e.g., via a background color or other inconspicuous notifier, e.g., on a mobile device such as a smart phone. The GUI may also be employed in the triggering of actionable alerts and alarms on an electronic device for the user. The GUI, or another index calculated from combinations of the variables and parameters described, may further be employed to drive a medicament delivery device such as a pump.

摘要翻译： 公开了在确定血糖紧急指数（GUI）中的几个或多个因素的系统和方法，其可以基于测量的血糖水平以及其他因素。 其他因素可以包括葡萄糖水平的时间导数和/或其他因素，例如用户输入的数据，由其他传感器测量或从网络源接收的数据或历史数据。 然后，以有趣的方式，例如通过背景颜色或其他不显眼的通知器（例如，诸如智能电话的移动设备）将GUI呈现给用户。 GUI也可以用于在用户的电子设备上触发可操作的警报和警报。 GUI或由所述变量和参数的组合计算出的另一指标可进一步用于驱动药物输送装置例如泵。

公开(公告)号：US20150118668A1

公开(公告)日：2015-04-30

申请号：US14526225

申请日：2014-10-28

申请人： DexCom, Inc.

发明人： Phil Mayou ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Laura J. Dunn ,  Katherine Yerre Grubstein ,  Aarthi Mahalingam ,  Eli Reihman ,  Peter C. Simpson

IPC分类号： A61B5/1455 ,  G09B19/00 ,  A61B5/00

CPC分类号： G09B5/02 ,  A61B5/01 ,  A61B5/1112 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14552 ,  A61B5/165 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  G06F19/3418 ,  G09B19/00 ,  G16H15/00 ,  G16H40/63 ,  G16H40/67 ,  H04L67/12

摘要： Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device.

摘要翻译： 描述了基于收集的信息连续地适应连续监视设备的各个方面以提供单独定制的配置的系统和方法。 修改可以包括调整用户界面，警报，激励消息，训练等。 这种适应可以允许患者更容易地识别和理解由/经由设备提供的信息。

公开(公告)号：US20140182350A1

公开(公告)日：2014-07-03

申请号：US13733742

申请日：2013-01-03

申请人： DEXCOM, INC.

发明人： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC分类号： G01M99/00

CPC分类号： G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G06F19/70 ,  G06F19/708

摘要： Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

摘要翻译： 提供了用于处理传感器数据和寿命终止检测的系统和方法。 在一些实施例中，用于确定连续分析物传感器的寿命终止的方法包括使用寿命终止功能评估多个危险因素以确定传感器的寿命状态并提供与寿命结束相关的输出 传感器的状态 可以从包括传感器已经使用的天数的列表中选择多个危险因素，信号灵敏度是否下降，是否存在预定的噪声模式，是否存在预定的氧浓度模式， 参考BG值和EGV传感器值之间的误差。