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    Systems for quickly delivering a prosthetic heart valve
    118.
    发明授权
    Systems for quickly delivering a prosthetic heart valve 有权
    用于快速输送假体心脏瓣膜的系统

    公开(公告)号：US09561100B2

    公开(公告)日：2017-02-07

    申请号：US14684267

    申请日：2015-04-10

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

    Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

    Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式，其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架，由此固定阀部件相对于基底支架的位置。 人造瓣膜可以是市售的，具有缝合环的阀门，并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。 提供了基于导管的系统和部署方法。

    Methods of deploying knotless suture anchoring clamps
    119.
    发明授权
    Methods of deploying knotless suture anchoring clamps 有权
    无缝缝合锚固夹具的部署方法

    公开(公告)号：US09504466B2

    公开(公告)日：2016-11-29

    申请号：US14797112

    申请日：2015-07-11

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  Donald E. Bobo, Jr.

    IPC: A61B17/04 ,  A61F2/24

    CPC classification number: A61B17/0487 ,  A61B17/0401 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0416 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2442

    Abstract: Methods of deploying knotless suture locking clamps for securing prostheses such as heart valves or annuloplasty rings to facilitate implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.

    Abstract translation: 部署用于固定假体（例如心脏瓣膜或瓣环成形术环）的无缝缝合锁定夹具的方法以便于植入。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。

    PRE-ASSEMBLED BIOPROSTHETIC VALVE CONDUIT AND METHOD OF DELIVERY
    120.
    发明申请
    PRE-ASSEMBLED BIOPROSTHETIC VALVE CONDUIT AND METHOD OF DELIVERY 审中-公开
    预组装的生物阀门管道和输送方法

    公开(公告)号：US20160270913A1

    公开(公告)日：2016-09-22

    申请号：US15079854

    申请日：2016-03-24

    Applicant: Edwards Lifesciences Corporation

    Inventor： Louis A. Campbell ,  Donald E. Bobo, JR. ,  Gregory A. Wright ,  Tak G. Cheung

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/0095 ,  A61F2/06 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2/2427 ,  A61F2210/0004 ,  A61F2220/0075 ,  A61F2310/00371 ,  A61F2310/00383 ,  A61L27/222 ,  A61L27/24 ,  A61L27/3625 ,  A61L27/3687 ,  A61L27/507 ,  A61L2430/20 ,  A61L2430/40

    Abstract: A valved conduit including a bioprosthetic valve, such as a heart valve, and a tubular conduit sealed with a bioresorbable material. The bioprosthetic heart valve includes prosthetic tissue that has been treated such that the tissue may be stored dry for extended periods without degradation of functionality of the valve. The bioprosthetic heart valve may have separate bovine pericardial leaflets or a whole porcine valve. The sealed conduit includes a tubular matrix impregnated with a bioresorbable medium such as gelatin or collagen. The valved conduit is stored dry in packaging in which a desiccant pouch is supplied having a capacity for absorbing moisture within the packaging limited to avoid drying the bioprosthetic tissue out beyond a point where its ability to function in the bioprosthetic heart valve is compromised. The heart valve may be sewn within the sealed conduit or coupled thereto with a snap-fit connection.

    Abstract translation: 包括生物假体瓣膜（例如心脏瓣膜）和用生物可再吸收材料密封的管状导管的阀门导管。 生物假体心脏瓣膜包括经过处理的假体组织，使得组织可以长时间保存干燥，而不会降低瓣膜的功能。 生物假体心脏瓣膜可以具有单独的牛心包瓣或整个猪瓣。 密封导管包括浸渍有生物可吸收介质如明胶或胶原的管状基质。 带阀的导管在包装中储存，其中提供干燥剂袋，其具有吸收包装内的水分的能力，以避免将生物假体组织干燥超过其在生物假体心脏瓣膜中起作用的能力受损的程度。 心脏瓣膜可以缝合在密封导管内或用卡扣配合连接在其上。

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