公开(公告)号：US20220374550A1

公开(公告)日：2022-11-24

申请号：US17771834

申请日：2020-10-29

Applicant: OSAKA UNIVERSITY

Inventor： Yasushi YAGI

IPC: G06F21/62

Abstract: A personal data distribution management system includes source data management devices, a data distribution management device, and a relay processing device that are separate devices and are connected on a network. The source data management device includes a database that stores personal data on an individual subjected to a measurement with a measuring instrument, and attribute information related to the individual and the measurement, the database storing the personal data and the attribute information as original data associated with real name information on the individual. The data distribution management device fetches original data except for personal data, and creates a data catalog. The relay processing device outputs the data, which is the data except for real name information on individuals and from the database of each source data management device based on the data usage request received from the outside, to a data user terminal. This configuration enables data distribution management that reduces the risk of information leakage of personal data and individual real name information.

公开(公告)号：US11509123B2

公开(公告)日：2022-11-22

申请号：US16319694

申请日：2017-07-25

Applicant: OSAKA UNIVERSITY

Inventor： Tsuyoshi Sekitani ,  Takafumi Uemura ,  Shusuke Yoshimoto ,  Teppei Araki ,  Yuki Noda ,  Takayasu Sakurai ,  Tokihiko Mori ,  Makoto Takamiya

IPC: H02G3/30 ,  G01M5/00 ,  G01N33/38 ,  H05K1/09

Abstract: A wiring sheet includes one or more carbon wires each of which is one of a signal line and a power supply line, and which are conductors including carbon as a main material and have flexibility; and an insulation sheet that encloses substantially an entirety of the one or more carbon wires, includes an electrical insulator as a main material, and has flexibility.

公开(公告)号：US11505605B2

公开(公告)日：2022-11-22

申请号：US15310162

申请日：2015-05-13

Applicant: Chugai Seiyaku Kabushiki Kaisha ,  Osaka University

Inventor： Tomoyuki Igawa ,  Takahiro Ishiguro ,  Shimon Sakaguchi ,  Hiroyoshi Nishikawa

IPC: C07K16/28 ,  C07K16/46 ,  C12N15/00 ,  A61K39/00

Abstract: It was discovered that antigen-binding molecules comprising (i) a domain that binds to a molecule expressed on the surface of cells having immune response-suppressing functions, and (ii) a T cell receptor complex-binding domain exhibit more superior antitumor effects than conventional antigen-binding molecules by crosslinking T cells with cells having immune response-suppressing functions, and damaging the cells having immune response-suppressing functions.

公开(公告)号：US20220337341A1

公开(公告)日：2022-10-20

申请号：US17673093

申请日：2022-02-16

Applicant: NEC CORPORATION ,  OSAKA UNIVERSITY ,  THE DOSHISHA

Inventor： Kazushi MURAOKA ,  Takanobu Doi ,  Naoto Ishii ,  Takumi Takahashi ,  Seiichi Sampei ,  Shinsuke Ibi

IPC: H04L1/00 ,  H04B7/0452

Abstract: A method implemented in a computer system includes training a network, which is obtained by unfolding an iterative algorithm for demodulation or demodulation and decoding, using a machine learning technique with a loss function that takes into account non-Gaussianity of a log-likelihood ratio (LLR) distribution calculated from an output of the network. The method further includes producing a first set of learned parameters of that iterative algorithm.

公开(公告)号：US11466987B2

公开(公告)日：2022-10-11

申请号：US16753176

申请日：2018-07-25

Applicant: TOKYO INSTITUTE OF TECHNOLOGY ,  OSAKA UNIVERSITY ,  JAPAN AVIATION ELECTRONICS INDUSTRY, LIMITED ,  MITSUBISHI HEAVY INDUSTRIES, LTD.

Inventor： Mikio Kozuma ,  Ryotaro Inoue ,  Takashi Mukaiyama ,  Utako Tanaka ,  Seiichi Morimoto ,  Kazunori Yoshioka ,  Atsushi Tanaka ,  Yuichiro Kamino

IPC: G01C19/58

Abstract: The present invention reduces measurement time. A gyroscope of the present invention includes a planar ion trap part, a microwave irradiation part, a laser irradiation part and a measurement part. The planar ion trap part includes two rf electrodes and two DC electrode rows, and forms ion traps that trap one ion on a substrate, a normal direction of the surface of the planar ion trap part corresponds to a z direction. The rf electrodes are disposed in the x direction on the substrate at a predetermined interval. The DC electrode rows are disposed in the x direction on the substrate so as to sandwich the two rf electrodes. The DC electrode rows each include at least five DC electrodes in the x direction. The trapped ions are spaced so as not to interfere with each other. The microwave irradiation part irradiates the ions with π/2 microwave pulses.

公开(公告)号：US20220298474A1

公开(公告)日：2022-09-22

申请号：US17633517

申请日：2020-08-06

Applicant: KAO CORPORATION ,  OSAKA UNIVERSITY

Inventor： Shiho YAMASHITA ,  Yoriko NAKAGIRI ,  Kiyotoshi SEKIGUCHI ,  Chisei SHIMONO

IPC: C12N5/071 ,  A61K35/36 ,  C07K14/78 ,  A61K8/98 ,  A61L27/38 ,  A61P17/14 ,  C12N5/10

Abstract: Provided is a method for efficiently culturing dermal papilla cells while maintaining an ability to induce hair follicles. A method for culturing dermal papilla cells in the presence of at least one selected from the group consisting of EMILIN and a fragment thereof.

公开(公告)号：US11446290B2

公开(公告)日：2022-09-20

申请号：US16626062

申请日：2018-06-27

Applicant: OSAKA UNIVERSITY

Inventor： Shoichi Shimada ,  Yukiko Yamamoto ,  Makoto Kondo

IPC: A61K31/4545 ,  A61P25/04

Abstract: The present invention provides a drug for preventing or treating chronic pain and a method for preventing or treating chronic pain. A pharmaceutical composition comprising a serotonin-3 receptor agonist such as a compound represented by the following formula (I): [wherein: m is an integer of 1 to 4; and R1 is each independently selected from the group consisting of a hydrogen atom, a halogen atom, a methyl group optionally substituted with 1 to 3 halogen atom(s), a methoxy group optionally substituted with 1 to 3 halogen atom(s), and a methylthio group optionally substituted with 1 to 3 halogen atom(s)] or a pharmaceutically acceptable salt thereof is useful for preventing or treating chronic pain. The above pharmaceutical composition is also useful for preventing or treating acute pain. Further, the present invention provides a method for screening a compound for preventing or treating chronic pain, the method comprising measuring a serotonin-3 receptor agonist activity.

公开(公告)号：US20220285589A1

公开(公告)日：2022-09-08

申请号：US17653868

申请日：2022-03-07

Applicant: National University Corporation Tokai National Higher Education and Research System ,  OSAKA UNIVERSITY ,  NICHIA CORPORATION

Inventor： Tsukasa TORIMOTO ,  Tatsuya KAMEYAMA ,  Chie MIYAMAE ,  Susumu KUWABATA ,  Taro UEMATSU ,  Tomoya KUBO

IPC: H01L33/50

Abstract: Provided is a method for producing semiconductor nanoparticles. The method includes: providing first semiconductor nanoparticles containing a semiconductor containing an element M1, an element M2 and an element Z, wherein the element M1 is at least one element selected from the group consisting of Ag, Cu, Au and an alkali metal, and contains at least Ag, the element M2 is at least one element selected from the group consisting of Al, Ga, In and Tl, and contains at least one of In and Ga, and the element Z contains at least one element selected from the group consisting of S, Se and Te; and heat-treating a mixture containing the first semiconductor nanoparticles, a first compound having a Ga—S bond, a second compound containing Ga and not containing S, and an organic solvent to obtain second semiconductor nanoparticles.

公开(公告)号：US20220275343A1

公开(公告)日：2022-09-01

申请号：US17638026

申请日：2020-10-07

Applicant: OSAKA UNIVERSITY

Inventor： Nobuyuki TAKAKURA ,  Hisamichi NAITO ,  Taku WAKABAYASHI ,  Tomohiro IBA

IPC: C12N5/071

Abstract: The present invention provides a method for artificially producing a vascular endothelial stem cell from a non-vascular endothelial stem cell. The method for producing a vascular endothelial stem cell of the present invention comprises the step of bringing a vascular endothelial cell possessing no stem cell properties into contact with a factor secreted by an organ of a neonatal or juvenile mammal. The step may be a step of (1) transplanting the vascular endothelial cell possessing no stem cell properties into the organ of the neonatal or juvenile mammal, wherein the mammal is a non-human mammal, or (2) culturing the vascular endothelial cell possessing no stem cell properties in a culture system containing the factor secreted by the organ of the neonatal or juvenile mammal.

公开(公告)号：US11427806B2

公开(公告)日：2022-08-30

申请号：US14916696

申请日：2014-09-04

Applicant: KYOTO UNIVERSITY ,  OSAKA UNIVERSITY ,  EISAI R&D MANAGEMENT CO., LTD.

Inventor： Jun Takahashi ,  Daisuke Doi ,  Bumpei Samata ,  Kiyotoshi Sekiguchi ,  Yuichi Ono

IPC: A61K35/30 ,  C12N5/0797 ,  C12N5/0793

Abstract: The present invention provides a method for producing dopaminergic neuron progenitor cells from pluripotent stem cells, which method comprises the steps of: (i) performing adherent culture of pluripotent stem cells on an extracellular matrix in a medium containing a reagent(s) selected from the group consisting of BMP inhibitor, TGFβ inhibitor, SHH signal-stimulating agent, FGF8, and GSK3β inhibitor; (ii) collecting Corin- and/or Lrtm1-positive cells from the cells obtained in Step (i) using a substance which binds to Corin and/or a substance which binds to Lrtm1; and (iii) performing suspension culture of the cells obtained in Step (ii) in a medium containing a neurotrophic factor.