公开(公告)号：US09250113B2

公开(公告)日：2016-02-02

申请号：US13805623

申请日：2011-06-16

申请人： Rashid Bashir ,  Kidong Park ,  Larry Millet ,  K. Jimmy Hsia ,  Narayana R. Aluru

发明人： Rashid Bashir ,  Kidong Park ,  Larry Millet ,  K. Jimmy Hsia ,  Narayana R. Aluru

IPC分类号： G01G9/00 ,  G01G3/00 ,  G01G3/16 ,  G01G19/14

CPC分类号： G01G19/14 ,  G01G3/16

摘要： Provided herein are sensors and methods for determining properties of single cells, such as cell mass. Sensors disclosed herein include resonant sensors having a suspended platform designed to exhibit a uniform vibration amplitude. Methods are also disclosed for measuring changes in cell mass, changes in cell number, changes in cell viscosity and changes in cell elasticity.

摘要翻译： 本文提供了用于确定单细胞（诸如细胞质量）的性质的传感器和方法。 本文公开的传感器包括谐振传感器，其具有设计成呈现均匀振动幅度的悬挂平台。 还公开了用于测量细胞质量变化，细胞数量变化，细胞粘度变化和细胞弹性变化的方法。

公开(公告)号：US09056747B2

公开(公告)日：2015-06-16

申请号：US13228710

申请日：2011-09-09

申请人： Beat Brügger ,  Christoph Schuler ,  Lukas Zeder ,  Thomas Wüest ,  Urs Schaffhauser ,  René Strebel

发明人： Beat Brügger ,  Christoph Schuler ,  Lukas Zeder ,  Thomas Wüest ,  Urs Schaffhauser ,  René Strebel

IPC分类号： B66B3/00 ,  G01G3/14 ,  G01L1/22 ,  B66B1/34 ,  G01G3/16 ,  G01G19/18

CPC分类号： B66B5/0006 ,  B66B1/3476 ,  B66B1/3484 ,  G01G3/16 ,  G01G19/18 ,  G01L1/22 ,  G01L5/00

摘要： An elevator installation includes an elevator cage with a support construction carrying the elevator cage, wherein the support construction has two beams. Mounted on each beam is a positioning arrangement on which, for example, a sensor is positioned, which is part of a load measuring device, wherein the positioning arrangements have material structures or sensor carriers. The sensors detect a change in spacing of the material structures or of the sensor carriers from one another, wherein this change in spacing is caused by a change in loading of the elevator cage. Signals of the sensors are processed in an evaluating unit and a signal representing the loading is used in an elevator control.

摘要翻译： 电梯安装包括具有承载电梯轿厢的支撑结构的电梯轿厢，其中支撑结构具有两个梁。 安装在每个梁上的是定位装置，例如，传感器被定位在其上，其是负载测量装置的一部分，其中定位装置具有材料结构或传感器载体。 传感器检测材料结构或传感器载体彼此的间隔的变化，其中间隔的这种变化是由电梯轿厢的负载变化引起的。 在评估单元中处理传感器的信号，并且在电梯控制中使用表示负载的信号。

公开(公告)号：US08413512B2

公开(公告)日：2013-04-09

申请号：US12515312

申请日：2007-11-16

申请人： Atsushi Itoh ,  Motoko Ichihashi

发明人： Atsushi Itoh ,  Motoko Ichihashi

IPC分类号： G01N29/00 ,  G01G3/16

CPC分类号： G01N29/022 ,  B01F11/0266 ,  B01F13/0059 ,  G01N29/036 ,  G01N29/222

摘要： It is an object of the invention to provide an agitation method for sufficiently agitating a mixture of a solution such as a buffer solution and a material to be detected, with no need of any dedicated unit for agitation, for measurements using a quartz crystal oscillator. The method for agitating a liquefied material using a quartz crystal oscillator in vibrating the quartz crystal oscillator at a given frequency and measuring the variation of the frequency due to a substance in contact with the quartz crystal oscillator, is that the quartz crystal oscillator is vibrated at other frequency different from the given frequency and equal to or higher than the fundamental vibration frequency to agitate a liquid containing the substance.

摘要翻译： 本发明的目的是提供一种搅拌方法，用于充分搅拌诸如缓冲溶液和待检测材料的溶液的混合物，而不需要任何专用搅拌单元，用于使用石英晶体振荡器进行测量。 使用石英晶体振荡器在给定频率下振动石英晶体振荡器并测量由于与石英晶体振荡器接触的物质引起的频率变化的液化材料的方法是石英晶体振荡器 其他频率与给定频率不同，等于或高于基本振动频率，以搅拌含有物质的液体。

公开(公告)号：US08051714B2

公开(公告)日：2011-11-08

申请号：US12311262

申请日：2007-09-27

申请人： Naoki Onishi ,  Hiroyuki Kukita ,  Shunichi Wakamatsu

发明人： Naoki Onishi ,  Hiroyuki Kukita ,  Shunichi Wakamatsu

IPC分类号： G01N5/02 ,  G01G3/16

CPC分类号： G01N29/036 ,  G01N5/02 ,  G01N29/022 ,  G01N29/30 ,  G01N2291/0256 ,  G01R31/2829

摘要： In a sensing instrument using a quartz sensor on whose front surface an adsorption layer for adsorbing a substance to be sensed is formed and which changes in natural frequency by the adsorption of the substance to be sensed, the present invention has an object to quickly detect a trouble of the quartz sensor to prevent an operator from recognizing an incorrect measurement result. In the present invention, a level detecting circuit detecting a signal level of an oscillation output of an oscillator circuit is provided, and after the time for stabilization passes after the power-on time, a computer takes a level detection value therein to compare the signal level and a threshold value. Then, when the signal level is lower than the threshold value, the signal level is determined as abnormal and, for example, the abnormality notification is displayed on a display unit, whereby an operator is notified of the occurrence of the abnormality.

摘要翻译： 在使用石英传感器的感测装置中，通过吸附待检测物质的表面形成吸附被检测物质的吸附层和固有频率的变化，本发明的目的是快速检测 石英传感器的故障，以防止操作者识别不正确的测量结果。 在本发明中，提供了检测振荡电路的振荡输出的信号电平的电平检测电路，并且在通电时间稳定的时间之后，计算机在其中进行电平检测值，以比较信号 水平和阈值。 然后，当信号电平低于阈值时，信号电平被确定为异常，并且例如，异常通知被显示在显示单元上，从而通知操作者异常的发生。

公开(公告)号：US06895829B2

公开(公告)日：2005-05-24

申请号：US10925514

申请日：2004-08-25

申请人： Yukihisa Takeuchi ,  Takao Ohnishi ,  Koji Kimura

发明人： Yukihisa Takeuchi ,  Takao Ohnishi ,  Koji Kimura

IPC分类号： B06B1/06 ,  G01G3/16 ,  G01H11/08 ,  G01N35/00 ,  G01P15/09 ,  G02B26/02 ,  H01L41/09 ,  H01L41/113 ,  H01L41/187 ,  G01P15/10

CPC分类号： G01P15/0922 ,  B06B1/06 ,  B06B1/0648 ,  G01G3/16 ,  G01H11/08 ,  G01N2035/00217 ,  G01N2035/00237 ,  G01N2291/02827 ,  G01P15/09 ,  G01P2015/0814 ,  H01L41/0973 ,  H01L41/1132

摘要： A mass sensor in which a connection plate and a diaphragm are joined together at their respective side; a sensing plate is joined to the connection plate at their respective sides in the direction perpendicular to the direction where the diaphragm is joined to the connection plate; a piezoelectric element consisting of a piezoelectric film and an electrode is installed on at least either one of plate surfaces of the sensing plate; and a resonating portion consisting of the diaphragm, the sensing plate, the connection plate, and the piezoelectric element is joined to a sensor substrate. Change in the mass of the diaphragm is measured by measuring change in the resonant frequency of the resonating portion accompanying the change in the mass of the diaphragm.

摘要翻译： 质量传感器，其中连接板和隔膜在它们各自的一侧接合在一起; 感测板在垂直于隔膜接合方向的连接板的相应侧面处连接到连接板; 由压电膜和电极构成的压电元件安装在感测板的板表面的至少任一个上; 并且由隔膜，感测板，连接板和压电元件组成的谐振部分接合到传感器基板。 通过测量伴随隔膜质量变化的谐振部分的谐振频率的变化来测量隔膜质量的变化。

公开(公告)号：US20050016301A1

公开(公告)日：2005-01-27

申请号：US10670506

申请日：2003-09-26

申请人： Ehud Elnatan ,  Yuval Lichi ,  Yossi Shomer ,  Shay Popper

发明人： Ehud Elnatan ,  Yuval Lichi ,  Yossi Shomer ,  Shay Popper

IPC分类号： G01G3/16 ,  G01N33/38 ,  G01G9/00

CPC分类号： G01G23/3728 ,  G01G3/16 ,  G01N33/381

摘要： The invention provides an apparatus for measuring the mass and calculating the weight of individual objects to be held thereby, comprising forceps having a proximal portion and a distal portion, the proximal portion being adapted to grasp and hold a selected object, means associated with the forceps for initiating vibration of the same while the object is held thereby and means for measuring the oscillating frequency of the forceps while the object is held thereby, and for utilizing the measured higher oscillating frequency of the empty forceps to compute the mass and the weight of the selected object.

公开(公告)号：US06840123B2

公开(公告)日：2005-01-11

申请号：US10465470

申请日：2003-06-19

申请人： Yukihisa Takeuchi ,  Takao Ohnishi ,  Koji Kimura

发明人： Yukihisa Takeuchi ,  Takao Ohnishi ,  Koji Kimura

IPC分类号： B06B1/06 ,  G01G3/16 ,  G01H11/08 ,  G01N35/00 ,  G01P15/09 ,  G02B26/02 ,  H01L41/09 ,  H01L41/113 ,  H01L41/187 ,  G01P15/10

CPC分类号： G01P15/0922 ,  B06B1/06 ,  B06B1/0648 ,  G01G3/16 ,  G01H11/08 ,  G01N2035/00217 ,  G01N2035/00237 ,  G01N2291/02827 ,  G01P15/09 ,  G01P2015/0814 ,  H01L41/0973 ,  H01L41/1132

摘要： A mass sensor is provided, including a sensor substrate, at least one connection plate having a first end attached to a first portion of the sensor substrate and an opposed second end, and at least one diaphragm attached to the second end of the connection plate. Means for changing the mass of the diaphragm is provided on the diaphragm, and at least one sensing plate having a first end attached to a second portion of the sensor substrate and an opposed second end is attached to one of the diaphragm and the connection plate. At least one piezoelectric element is arranged on at least a portion of a surface of the sensing plate. The sensing plate and sensor substrate are arranged in one of a substantially parallel planar or coplanar relationship with respect to one another, and the connection plate, diaphragm, sensing plate and piezoelectric element define a resonance portion.

摘要翻译： 提供了一种质量传感器，包括传感器基板，至少一个连接板，其具有附接到传感器基板的第一部分的第一端和相对的第二端，以及附接到连接板的第二端的至少一个隔膜。 用于改变隔膜的质量的装置设置在隔膜上，并且至少一个传感板，其具有附接到传感器基板的第二部分的第一端和相对的第二端，附接到隔膜和连接板中的一个。 至少一个压电元件布置在感测板的表面的至少一部分上。 感测板和传感器基板相对于彼此基本上平行的平面或共面关系中的一个布置，并且连接板，隔膜，感测板和压电元件限定共振部分。

公开(公告)号：US6080939A

公开(公告)日：2000-06-27

申请号：US97043

申请日：1998-06-12

申请人： David R. Hassel

发明人： David R. Hassel

IPC分类号： G01G3/16 ,  G01G3/18 ,  G01N5/02 ,  G01G3/14 ,  G01G9/00 ,  G01G19/56

CPC分类号： G01G3/18

摘要： A mass determination device includes a combination of an elastic element connected with a mass holder. The combination has a normalized temperature coefficient of frequency substantially equal to zero over a temperature range of intended use for the mass determination device, whereby mass determination accuracy of the device during temperature change in the range is enhanced. The elastic element has a first normalized temperature coefficient of frequency over the temperature range. A second normalized temperature coefficient of frequency over the temperature range attributable to the mass holder is determined. The first normalized temperature coefficient and the second normalized temperature coefficient are substantially counterbalanced over the temperature range, for example, through material selection and/or heat treatment of the elastic element and/or material or geometry variation of the mass holder.

摘要翻译： 质量确定装置包括与质量保持器连接的弹性元件的组合。 该组合在质量确定装置的预期用途的温度范围内具有基本上等于零的频率的归一化温度系数，从而提高了在该范围内的温度变化期间装置的质量确定精度。 弹性元件在温度范围内具有第一归一化温度系数。 确定归因于质量保持器的温度范围上的频率的第二归一化温度系数。 第一归一化温度系数和第二归一化温度系数在温度范围内基本上是平衡的，例如通过弹性元件的材料选择和/或热处理和/或材料夹持器的材料或几何变化。

公开(公告)号：US5910647A

公开(公告)日：1999-06-08

申请号：US729752

申请日：1996-10-07

申请人： Vyacheslav D. Kats ,  Arnold S. Gordon

发明人： Vyacheslav D. Kats ,  Arnold S. Gordon

IPC分类号： G01G3/13 ,  G01G3/14 ,  G01G3/16 ,  G01G3/18 ,  G01L1/00

CPC分类号： G01G3/13

摘要： A weighing apparatus includes a base supporting a cantilevered elastic member bearing a load platform. The interior of the elastic member is hollowed and is provided with first and second piezoelectric transducers mounted on respective opposed posts. The transducers are arranged substantially parallel to each other with a small gap between them and are coupled to an amplifier to form a "delay line" and a positive feedback loop, i.e. a natural oscillator. According to various aspects of the invention, one or both substrates is provided with anti-reflection structure; the transducers are arranged on overlapping substrates to further reduce reflection; the transducers are coupled to a thermal sink to reduce the effects of thermal gradients across the transducers; two pairs of transducers are provided and arranged to provide a pair of oppositely polarized signals which doubles the accuracy of measurements and also compensates for the effects of temperature gradients; a thermal transducer channel is provided on the same substrate to measure the effects of temperature gradients and thereby compensate for temperature effects; a pair of differential transducers is arranged to measure the effects of temperature changes in the same acoustic channel in which displacement measurements are made; and a phase shift is applied to the output of the amplifier(s) to improve gain.

摘要翻译： 一种称重设备包括支撑承载负载平台的悬臂弹性构件的基座。 弹性构件的内部是中空的，并且设置有安装在各自相对的柱上的第一和第二压电换能器。 换能器基本上彼此平行布置，并且在它们之间具有小的间隙，并且耦合到放大器以形成“延迟线”和正反馈回路，即天然振荡器。 根据本发明的各个方面，一个或两个基板设有防反射结构; 换能器被布置在重叠的基底上以进一步减少反射; 传感器耦合到散热器，以减少穿过换能器的热梯度的影响; 提供并配置了两对换能器，以提供一对相反极化的信号，使得测量精度增加一倍，并补偿温度梯度的影响; 在同一基板上提供热传感器通道以测量温度梯度的影响，从而补偿温度影响; 布置一对差动换能器来测量在进行位移测量的同一声道中的温度变化的影响; 并且对放大器的输出施加相移以改善增益。

公开(公告)号：US5902964A

公开(公告)日：1999-05-11

申请号：US915867

申请日：1997-08-21

申请人： Ruell F. Solberg, Jr. ,  H. Stanley Silvus

发明人： Ruell F. Solberg, Jr. ,  H. Stanley Silvus

IPC分类号： G01G3/16 ,  G01G3/14

CPC分类号： G01G3/16

摘要： A method for measuring the masses of objects in any gravity environment, including microgravity or zero gravity. An object is placed on or attached to a platform that is movable back and forth along a single axis of motion. An actuator is used to oscillate the platform and is controlled to provide a variable spring force. Instantaneous displacement values are obtained and used to calculate the period of oscillation. Values representing the period, the tare mass of the platform, and the spring constant are then used to calculate the mass of the object. The method may use active damping, and may be varied so that the oscillations are angular rather than linear.

摘要翻译： 一种在任何重力环境中测量物体质量的方法，包括微重力或零重力。 物体被放置在平台上或附接到可沿着单个运动轴线来回移动的平台上。 致动器用于振荡平台并被控制以提供可变的弹簧力。 获得瞬时位移值并用于计算振荡周期。 然后使用表示周期的值，平台的皮重和弹簧常数来计算物体的质量。 该方法可以使用主动阻尼，并且可以变化，使得振荡是有角度的而不是线性的。