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    Antimicrobial polymeric film
    121.
    发明授权
    Antimicrobial polymeric film 有权
    抗微生物聚合物膜

    公开(公告)号：US07705078B2

    公开(公告)日：2010-04-27

    申请号：US11630366

    申请日：2005-06-20

    申请人： William Alasdair MacDonald ,  Julia Elizabeth Friend Angold ,  David Brown

    发明人： William Alasdair MacDonald ,  Julia Elizabeth Friend Angold ,  David Brown

    IPC分类号： C08K3/10

    CPC分类号： A01N59/16 ,  A01N25/34 ,  A01N25/10 ,  A01N2300/00

    摘要： An anti-microbial polymeric film comprising a polymeric substrate layer and an inorganic anti-microbial compound of formula (I): AgaHbAcM2(PO4)3.nH2O wherein: A is at least one ion selected from an alkali or alkaline earth metal ion; M is a tetravalent metal ion; a is in the range 0.4 to 0.5; b and c are positive numbers such that (a+b+mc)=1; m is the valence of metal A; and 0≦n≦6, wherein the anti-microbial compound is present in the substrate layer in an amount of from about 0.05 to about 0.7% of by weight of the polymeric material of the substrate layer; and the use of said inorganic anti-microbial compound for providing an antimicrobial polymeric film having reduced haze.

    摘要翻译： 一种抗微生物聚合物膜，其包含聚合物基底层和式（I）的无机抗微生物化合物：AgaHbAcM2（PO4）3·nH2O其中：A是选自碱金属或碱土金属离子中的至少一种离子; M是四价金属离子; a在0.4〜0.5的范围内; b和c是正数，使得（a + b + mc）= 1; m是金属A的化合价; 和其中所述抗微生物化合物以所述基材层的聚合物材料的约0.05至约0.7重量％的量存在于所述基材层中; 以及使用所述无机抗微生物化合物来提供具有降低的雾度的抗微生物聚合物膜。

    MIRNAS DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS
    123.
    发明申请
    MIRNAS DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS 审中-公开
    来自癌症患者的淋巴细胞淋巴细胞明显不同

    公开(公告)号：US20090263803A1

    公开(公告)日：2009-10-22

    申请号：US12368053

    申请日：2009-02-09

    申请人： Sylvie Beaudenon ,  Laura Elizondo ,  Martina Doleshal ,  David Brown ,  Emmanuel Labourier

    发明人： Sylvie Beaudenon ,  Laura Elizondo ,  Martina Doleshal ,  David Brown ,  Emmanuel Labourier

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6886 ,  C12N15/111 ,  C12N2310/141 ,  C12N2320/10 ,  C12N2330/10 ,  C12Q2600/112 ,  C12Q2600/178

    摘要： The present invention provides diagnostics and/or prognostic methods by identifying miRNAs that are differentially expressed or mis-regulated in various states of diseased, normal, cancerous, and/or abnormal tissues, including but not limited to cervix, skin, colon, breast, bladder, esophagus, liver, ovary, prostate, lung, pancreas, thyroid, kidney, stomach, testicle, uterus, spleen, tongue, brain, thymus, trachea and/or small intestine. In certain apsects, differential miRNA expression is initially determined by comparing miRNA expression between a normal tissue and cancer negative lymph node (LNneg), a normal tissue and a cancer positive lymph node (LNpos), a cancerous tissue and LNneg and/or LNpos, LNneg and LNpos. The methods of the invention are used to identify the presence or absence of non-lymphoid cells from other organs or tissues, and/or metastatic cancer cells present in lymph nodes.

    摘要翻译： 本发明通过鉴定在患病，正常，癌性和/或异常组织的各种状态中差异表达或错误调节的miRNA来提供诊断和/或预后方法，包括但不限于子宫颈，皮肤，结肠，乳房， 膀胱，食管，肝，卵巢，前列腺，肺，胰腺，甲状腺，肾，胃，睾丸，子宫，脾，舌，脑，胸腺，气管和/或小肠。 在某些apsects中，差异miRNA表达最初通过比较正常组织和癌症阴性淋巴结（LNneg），正常组织和癌淋巴结（LNpos），癌组织和LNneg和/或LNpos之间的miRNA表达来确定， LNneg和LNpos。 本发明的方法用于鉴定存在于淋巴结中的其它器官或组织和/或转移性癌细胞的非淋巴细胞的存在或不存在。

    Medical information card
    124.
    发明申请
    Medical information card 审中-公开
    医疗信息卡

    公开(公告)号：US20090248446A1

    公开(公告)日：2009-10-01

    申请号：US12384042

    申请日：2009-03-31

    申请人： Stacey L. Grigsby ,  David Brown

    发明人： Stacey L. Grigsby ,  David Brown

    IPC分类号： G06Q50/00

    CPC分类号： G06Q50/24 ,  G16H10/20 ,  G16H10/65

    摘要： A device for storing, transporting and maintaining a user's medical history and condition. The device comprises a flash drive which is preprogrammed with a form ready to be filled out, edited or appended with all of the user's medical information. The form is in OMNIFORM® mailable filler format commonly used in the medical industry.

    摘要翻译： 一种用于存储，运输和维护用户的病史和状况的装置。 该装置包括一个闪存驱动器，该闪存驱动器被预编程有准备填写，编辑或附加所有用户医疗信息的形式。 该形式是在医疗行业中常用的OMNIFORM（R）可用填充剂形式。

    OPTICAL DISC MAILCARD
    130.
    发明申请
    OPTICAL DISC MAILCARD 审中-公开
    光盘碟

    公开(公告)号：US20080128302A1

    公开(公告)日：2008-06-05

    申请号：US11833772

    申请日：2007-08-03

    申请人： Edward H. Bohlke ,  Laura Smith ,  David Brown ,  Sydney Wood ,  Rachel Goodman

    发明人： Edward H. Bohlke ,  Laura Smith ,  David Brown ,  Sydney Wood ,  Rachel Goodman

    IPC分类号： B65D85/57

    CPC分类号： B65D27/04 ,  B65D27/22 ,  B65D27/34 ,  G11B33/0422 ,  G11B33/0494

    摘要： The invention provides packaging and mailable apparatus suitable for a variety of uses, such as in the postal system for the purpose of mailing, mass mailing, or self-mailing of optical discs or other optical and non-optical cards, displaying such discs or cards at point of purchase locations, and/or carrying them in one's wallet or pocket. Such packaging comprises mailcards, such as standard postcards or greeting cards; card-sized gift packaging; or protective packaging of various sizes, which such packages house optical discs or cards that may or may not be visible through the packaging.

    摘要翻译： 本发明提供了适用于各种用途的包装和可用设备，例如在邮政系统中用于邮寄，大量邮寄或光盘或其他光学和非光学卡的自发邮件，显示这种光盘或卡片 在购买地点，和/或携带他们在钱包或口袋里。 这种包装包括诸如标准明信片或贺卡的邮件卡; 卡片尺寸礼品包装; 或各种尺寸的保护性包装，这些包装件容纳可能通过包装或可能不可见的光盘或卡。