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    Multi-conjugate of siRNA and preparing method thereof
    131.
    发明授权
    Multi-conjugate of siRNA and preparing method thereof 有权
    siRNA的多重缀合物及其制备方法

    公开(公告)号：US08580946B2

    公开(公告)日：2013-11-12

    申请号：US12514306

    申请日：2009-04-29

    Applicant: Tae Gwan Park ,  Hye Jung Mok ,  Soo Hyeon Lee

    Inventor： Tae Gwan Park ,  Hye Jung Mok ,  Soo Hyeon Lee

    IPC: C07H21/04 ,  C12N15/113

    CPC classification number: C12N15/1136 ,  C12N15/111 ,  C12N15/113 ,  C12N2310/14 ,  C12N2310/51

    Abstract: The present invention relates to a multi-conjugate of small interfering RNA (siRNA) and a preparing method of the same, more precisely a multi-conjugate of siRNA prepared by direct binding of double stranded sense/antisense siRNA monomers or indirect covalent bonding mediated by a cross-linking agent or a polymer, and a preparing method of the same. The preparing method of a siRNA multi-conjugate of the present invention is characterized by simple and efficient reaction and thereby the prepared siRNA multi-conjugate of the present invention has high molecular weight multiple times the conventional siRNA, so that it has high negative charge density, suggesting that it has excellent ionic interaction with a cationic gene carrier and high gene delivery efficiency.

    Abstract translation: 本发明涉及小干扰RNA（siRNA）的多重缀合物及其制备方法，更准确地说是通过双链有义/反义siRNA单体的直接结合制备的siRNA的多重缀合物或间接共价结合 交联剂或聚合物及其制备方法。 本发明的siRNA多偶联物的制备方法的特征在于简单且有效的反应，由此制备的本发明的siRNA多偶联物具有高分子量多次的常规siRNA，因此具有高的负电荷密度 表明它与阳离子基因载体具有优异的离子相互作用和高基因传递效率。

    Expression vector for gene therapy
    132.
    发明授权
    Expression vector for gene therapy 有权
    基因治疗的表达载体

    公开(公告)号：US08569051B2

    公开(公告)日：2013-10-29

    申请号：US13423652

    申请日：2012-03-19

    Applicant: Daekyung Koh ,  Kyuhyun Lee ,  Hyeon Lee ,  Seongtae Yun ,  Eui-Cheol Jo

    Inventor： Daekyung Koh ,  Kyuhyun Lee ,  Hyeon Lee ,  Seongtae Yun ,  Eui-Cheol Jo

    IPC: C12N15/63 ,  C12N15/113 ,  C07H21/04

    CPC classification number: C12N15/63

    Abstract: Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc.

    Abstract translation: 提供了具有转录调节元件的新组合的基因治疗的表达载体，其包括启动子，增强子，内含子，非翻译区（UTR）和基因座控制区（LCR）。 表达载体能够持续表达肝组织特异性基因，因此可有效用于治疗血栓形成，血友病，肝癌等。

    Method of forming fine patterns of semiconductor device by using double patterning process which uses acid diffusion
    135.
    发明授权
    Method of forming fine patterns of semiconductor device by using double patterning process which uses acid diffusion 有权
    通过使用酸扩散的双重图案化工艺形成半导体器件精细图案的方法

    公开(公告)号：US08431331B2

    公开(公告)日：2013-04-30

    申请号：US12267687

    申请日：2008-11-10

    Applicant: Yool Kang ,  Suk-joo Lee ,  Jung-hyeon Lee ,  Shi-yong Yi

    Inventor： Yool Kang ,  Suk-joo Lee ,  Jung-hyeon Lee ,  Shi-yong Yi

    IPC: G03F7/40

    CPC classification number: H01L21/027 ,  G03F7/0035 ,  G03F7/40 ,  H01L21/0273 ,  H01L21/0338 ,  H01L21/32139

    Abstract: A method of forming fine patterns of a semiconductor device according to a double patterning process that uses acid diffusion is provided. In this method, a plurality of first mask patterns are formed on a substrate so as to be separated from one another. A capping film including an acid source is formed on sidewalls and an upper surface of each of the plurality of first mask patterns. A second mask layer is formed on the capping films. A plurality of acid diffused regions are formed within the second mask layer by diffusing acid obtained from the acid source from the capping films into the second mask layer. A plurality of second mask patterns are formed of residual parts of the second mask layer which remain in the first spaces after removing the acid diffused regions of the second mask layer.

    Abstract translation: 提供了根据使用酸扩散的双重图案化工艺形成半导体器件的精细图案的方法。 在该方法中，在基板上形成多个第一掩模图案以彼此分离。 在多个第一掩模图案的每一个的侧壁和上表面上形成包括酸源的封盖膜。 在封盖膜上形成第二掩模层。 通过将从酸源获得的酸从封盖膜扩散到第二掩模层中，在第二掩模层内形成多个酸扩散区。 多个第二掩模图案由除去第二掩模层的酸扩散区域之后残留在第一间隙中的第二掩模层的残留部分形成。

    LIGHT MODULE AND BACKLIGHT ASSEMBLY INCLUDING THE SAME
    136.
    发明申请
    LIGHT MODULE AND BACKLIGHT ASSEMBLY INCLUDING THE SAME 有权
    光模块和背光组件，包括它们

    公开(公告)号：US20130077348A1

    公开(公告)日：2013-03-28

    申请号：US13525167

    申请日：2012-06-15

    Applicant: Sang-Chul BYUN ,  Seok Hyun NAM ,  Si Joon SONG ,  Yong Suk CHI ,  Min-Young SONG ,  Young-Keun LEE ,  Hyuk-Hwan KIM ,  Dong Hyeon LEE

    Inventor： Sang-Chul BYUN ,  Seok Hyun NAM ,  Si Joon SONG ,  Yong Suk CHI ,  Min-Young SONG ,  Young-Keun LEE ,  Hyuk-Hwan KIM ,  Dong Hyeon LEE

    IPC: F21V8/00 ,  F21V21/00

    CPC classification number: F21S8/00 ,  F21V19/00 ,  F21V23/00 ,  F21V23/001 ,  G02B6/0068 ,  G02B6/0073 ,  G02B6/0083 ,  G02F1/133615 ,  H05K1/0278 ,  H05K1/14 ,  H05K2201/10106

    Abstract: A light module for a backlight assembly that prevents metal wiring from being damaged at a bent portion and a backlight assembly including the same are presented. The light module for the backlight assembly includes: a printed circuit board (PCB) including a first portion and a second portion connected by a connection having a bend; a first light source formed on the first portion of the printed circuit board (PCB); a second light source formed on the second portion of the printed circuit board (PCB); a first wiring connecting member connected to the first light source and formed on the first portion; and a second wiring connecting member connected to the second light source and formed on the second portion, wherein the first wiring connecting member and the second wiring connecting member are connected to each other.

    Abstract translation: 本发明提供了一种用于防止金属布线在弯曲部分被损坏的背光组件的灯组件和包括其的背光组件。 用于背光组件的灯模块包括：印刷电路板（PCB），包括第一部分和通过具有弯曲部的连接部连接的第二部分; 形成在印刷电路板（PCB）的第一部分上的第一光源; 形成在印刷电路板（PCB）的第二部分上的第二光源; 连接到第一光源并形成在第一部分上的第一布线连接构件; 以及与第二光源连接并形成在第二部分上的第二布线连接构件，其中第一布线连接构件和第二布线连接构件彼此连接。

    Second order noise coupling with zero optimization modulator and method
    137.
    发明授权
    Second order noise coupling with zero optimization modulator and method 有权
    二阶噪声耦合与零优化调制器和方法

    公开(公告)号：US08390494B2

    公开(公告)日：2013-03-05

    申请号：US13006637

    申请日：2011-01-14

    Applicant: Jeong Seok Chae ,  Sang Hyeon Lee ,  Gábor C. Temes

    Inventor： Jeong Seok Chae ,  Sang Hyeon Lee ,  Gábor C. Temes

    IPC: H03M3/00

    CPC classification number: H03M3/446 ,  H03M3/424

    Abstract: A method and apparatus for a modified noise-coupled modulator using zero optimization technique is disclosed. By realizing the resonator coefficient as a part of branches other than those of the main transfer function, the problem of improving SQNR without degrading other specifications is solved. Second order noise coupling is used to implement zeros without using feedback branches going into the first integrator. Embodiments use a first-order modulator, second-order noise coupling and a resonator. It allows lower power consumption and smaller size by removing small capacitor values and gain factors and reducing the number of amplifiers.

    Abstract translation: 公开了一种使用零优化技术的改进的噪声耦合调制器的方法和装置。 通过实现作为主传递函数以外的分支的一部分的谐振器系数，解决了改善SQNR而不降低其他规格的问题。 二阶噪声耦合用于实现零，而不使用进入第一积分器的反馈分支。 实施例使用一阶调制器，二阶噪声耦合和谐振器。 通过去除小电容值和增益因子并减少放大器的数量，可以实现更低的功耗和更小的尺寸。

    Organic light emitting device
    139.
    发明授权
    Organic light emitting device 失效
    有机发光装置

    公开(公告)号：US08283852B2

    公开(公告)日：2012-10-09

    申请号：US12473904

    申请日：2009-05-28

    Applicant: Sung-Soo Lee ,  Joo-Hyeon Lee

    Inventor： Sung-Soo Lee ,  Joo-Hyeon Lee

    IPC: H01L51/50

    CPC classification number: H01L51/5265 ,  H01L51/5215

    Abstract: An organic light emitting device includes: a substrate; thin film structures formed on the substrate; a pixel electrode including a metal layer formed on the thin film structures, and a transparent conductor layer formed on the metal layer; a common electrode facing the pixel electrode; and an organic light emitting member disposed between the pixel electrode and the common electrode, wherein the organic light emitting member includes an emission layer and a plurality of auxiliary layers, and the profile thickness of a first layer as at least one layer among the emission layer and the auxiliary layers on the substrate is different from the profile thickness of at least one second layer that is different from the first layer among the emission layer and the auxiliary layers.

    Abstract translation: 一种有机发光器件包括：衬底; 形成在基板上的薄膜结构; 包括形成在所述薄膜结构上的金属层的像素电极和形成在所述金属层上的透明导体层; 面对像素电极的公共电极; 以及设置在所述像素电极和所述公共电极之间的有机发光部件，其中所述有机发光部件包括发光层和多个辅助层，并且所述发光层中的至少一层的第一层的轮廓厚度 衬底上的辅助层与发光层和辅助层中与第一层不同的至少一个第二层的轮廓厚度不同。

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