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    NOVEL COMPOUND AND USE THEREOF
    136.
    发明申请
    NOVEL COMPOUND AND USE THEREOF 有权

    公开(公告)号：US20230095498A1

    公开(公告)日：2023-03-30

    申请号：US17794823

    申请日：2021-01-14

    Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION

    Inventor： Chul-Woov YANG ,  Dong-Yun SHIN ,  Mi-La CHO ,  Seon-Yeong LEE ,  Sun-Woo LIM ,  Yoo-Jin SHIN

    IPC: C07D401/14 ,  A61P13/12 ,  A61P29/00

    Abstract: Provided is a novel compound and use thereof which has an excellent immunological regulation ability while not exhibiting toxicity in vivo, and has no nephrotoxicity and rather has a kidney protective effect, and thus can be used for the treatment of immune diseases such as autoimmune diseases caused by abnormal regulation of various immune responses, inflammatory diseases, and transplant rejection diseases. A transplant rejection avatar animal model was confirmed to be humanized, by confirming an increase in serum creatinine, an indicator of transplant rejection in a patient, an increase in human CD4-positive cells, and infiltration of inflammatory cytokine IL-17 into kidney tissue of the animal model. It was confirmed that, when an immunosuppressant is administered, the increased serum creatinine, human CD4-positive cells, and the infiltration of inflammatory cytokine IL-17 are reduced, and thus an animal model, in which the immune status of a patient is reflected, is effectively constructed.

    SURGICAL PIN GUIDE
    137.
    发明申请
    SURGICAL PIN GUIDE 有权

    公开(公告)号：US20230087824A1

    公开(公告)日：2023-03-23

    申请号：US17909064

    申请日：2020-12-22

    Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION

    Inventor： Seok Jung KIM

    IPC: A61B17/17

    Abstract: Disclosed is a surgical pin guide. To this end, the present invention provides a surgical pin guide including a guide fixed to an outer circumferential surface of a femur and configured to allow a center pin and a central pressure reducer of a drill handpiece to approach a necrotic region of an expanded area, a guide main body including a handle provided on an upper surface of a block, a center pin-guide hole horizontally pierced at a center of a front surface of the block, and a plurality of side pin-guide holes pierced at predetermined inclination angles with respect to the center pin-guide hole, arranged radially in the front surface of the block, and configured to meet the center pin-guide hole in a rear surface of the block, and a leading body configured to allow the guide main body to be detached from the guide and approach the necrotic region of the femoral head in a rotationally folded state.

    MULTILAYER CORNEA HARVESTING APPARATUS AND CORNEA HARVESTING METHOD USING SAME
    138.
    发明申请
    MULTILAYER CORNEA HARVESTING APPARATUS AND CORNEA HARVESTING METHOD USING SAME 有权

    公开(公告)号：US20220378979A1

    公开(公告)日：2022-12-01

    申请号：US17782265

    申请日：2020-08-07

    Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION

    Inventor： Dong Jin CHANG ,  Hosik HWANG

    IPC: A61L27/36

    Abstract: A multilayer cornea harvesting apparatus capable of obtaining layers of cornea from one cornea enucleation object and a cornea harvesting method is disclosed. The apparatus includes a base supported on a bottom surface, a mount detachably coupled to the base, allowing a cornea enucleation object to be placed thereon, having a first opening part formed at a portion corresponding to the cornea of the cornea enucleation object, and having a first medicinal fluid charging space formed between the base and the mount, a stabilizer fixing, to the mount, a sclera portion of the cornea enucleation object placed on the mount and having a second opening part formed at a portion corresponding to the cornea, and an upper cover detachably provided on the upper side of the cornea, supported by the mount or supporting the mount, and forming a second medicinal fluid charging space on the upper side of the cornea.

    Medical test slide unit
    140.
    发明授权
    Medical test slide unit 有权

    公开(公告)号：US11440011B2

    公开(公告)日：2022-09-13

    申请号：US16493095

    申请日：2018-01-22

    Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION

    Inventor： Yeon Joon Park ,  Kang Gyun Park

    IPC: B01L9/00 ,  B01L3/00

    Abstract: Provided is a medical test slide unit including a frame main body including: a marker part which has a thin plate shape and in which a plurality of position indicating markers are formed longitudinally and transversely; and a border part arranged to surround the marker part, wherein a step is formed between the border part and the marker part to form a seating recess, and wherein a slide, on which a specimen to be examined using a microscope is placed, is selectively seated in the seating recess.

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