公开(公告)号：US20140131562A1

公开(公告)日：2014-05-15

申请号：US14076502

申请日：2013-11-11

申请人： Gangbing Song ,  Siu Chun Michael Ho ,  Ren Liang ,  Hongnan Li

发明人： Gangbing Song ,  Siu Chun Michael Ho ,  Ren Liang ,  Hongnan Li

IPC分类号： G01H9/00

CPC分类号： G01H9/004 ,  G01D5/35316

摘要： A fiber Bragg grating (FBG) interrogation method allows for high frequency dynamic measurement. The method may utilize a broad band light source connected to the sensing elements. Each sensing element may comprise two wavelength matching FBGs, a coupler, and a photodiode. The FBG closest to the light source may attenuate the central wavelength in the transmission spectrum and thus the reflection spectrum of the second FBG. Variations in intensity of the second FBG may be measured by the photodiode and can be calibrated to the desired measurands.

摘要翻译： 光纤布拉格光栅（FBG）询问方法允许高频动态测量。 该方法可以利用连接到感测元件的宽带光源。 每个感测元件可以包括两个波长匹配FBG，耦合器和光电二极管。 最靠近光源的FBG可以衰减透射光谱中的中心波长，从而衰减第二FBG的反射光谱。 可以通过光电二极管测量第二FBG的强度变化，并且可以校准到所需的被测量。

公开(公告)号：US20140127609A1

公开(公告)日：2014-05-08

申请号：US14152697

申请日：2014-01-10

申请人： The University of Houston System

发明人： Allan J. Jacobson ,  Shuangyan Wang ,  Gun Tae Kim

IPC分类号： H01M4/90 ,  H01M8/12

CPC分类号： H01M4/9033 ,  H01M8/1246 ,  Y02E60/521 ,  Y02E60/525 ,  Y02P70/56

摘要： Methods using novel cathode, electrolyte and oxygen separation materials operating at intermediate temperatures for use in solid oxide fuel cells and ion transport membranes include oxides with perovskite related structures and an ordered arrangement of A site cations. The materials have significantly faster oxygen kinetics than in corresponding disordered perovskites.

摘要翻译： 使用在中等温度下操作用于固体氧化物燃料电池和离子迁移膜的新型阴极，电解质和氧分离材料的方法包括具有钙钛矿相关结构的氧化物和A位阳离子的有序排列。 与相应的无序钙钛矿相比，这些材料具有显着更快的氧动力学。

公开(公告)号：US20140111231A1

公开(公告)日：2014-04-24

申请号：US14058547

申请日：2013-10-21

申请人： Yi-Lung Mo ,  Rachel Howser ,  Hermant Dhonde ,  Gangbing Song

发明人： Yi-Lung Mo ,  Rachel Howser ,  Hermant Dhonde ,  Gangbing Song

IPC分类号： G01R27/14 ,  B29C39/00

CPC分类号： G01R27/14 ,  B28B17/0072 ,  G01M5/0041 ,  G01M5/0083 ,  G01N27/041 ,  G01N33/383 ,  Y10T442/10

摘要： A carbon nanofiber aggregate (CNFA) system and method provides self-sensing capabilities that can be used to detect strain, moisture, and temperature changes. The CNFA may include cement, aggregate, silica fume, high-range water reducer (HRWR), and/or carbon nanofibers. The metal meshes in the CNFA may be utilized to monitor the electric properties of the CNFA to detect strain, moisture, and temperature changes. The CNFA may be embedded in concrete structures to allow detection of strain, moisture, and temperature changes that may cause damage to structures. Several metal meshes may be embedded in the CNFA.

摘要翻译： 碳纳米纤维聚集体（CNFA）系统和方法提供了可用于检测应变，湿度和温度变化的自我感应能力。 CNFA可以包括水泥，骨料，硅灰，高效减水剂（HRWR）和/或碳纳米纤维。 CNFA中的金属网可用于监测CNFA的电性能，以检测应变，湿度和温度变化。 CNFA可以嵌入混凝土结构中，以便检测可能导致结构损坏的应变，水分和温度变化。 可以在CNFA中嵌入几个金属网。

公开(公告)号：US08701406B2

公开(公告)日：2014-04-22

申请号：US12842003

申请日：2010-07-22

申请人： Garrett Lewis ,  Gangbing Song ,  Devendra Patil

发明人： Garrett Lewis ,  Gangbing Song ,  Devendra Patil

IPC分类号： F01B29/10 ,  F02G1/04

CPC分类号： F15B5/006 ,  E21B33/064 ,  E21B41/0007 ,  F03G7/065

摘要： A system, in certain embodiments, includes an accumulator having a first plate with a first wire guide and a second plate with a second wire guide. The second plate is positioned at an offset from the first plate, and the second plate is moveable relative to the first plate to adjust a fluid pressure. The accumulator also includes a plurality of shape memory alloy wires extending between the first and second plates, wherein the plurality of shape memory alloy wires extend along the first and second wire guides.

摘要翻译： 在某些实施例中，系统包括具有带有第一导线引导件的第一板和具有第二导线器的第二板的蓄电池。 第二板位于与第一板偏移的位置，第二板相对于第一板移动以调节流体压力。 蓄电池还包括在第一和第二板之间延伸的多个形状记忆合金线，其中​​多个形状记忆合金线沿着第一和第二线引导件延伸。

公开(公告)号：US08669335B2

公开(公告)日：2014-03-11

申请号：US13028057

申请日：2011-02-15

申请人： Rigoberto Advincula

发明人： Rigoberto Advincula

IPC分类号： C09D133/12 ,  C08F8/48

CPC分类号： C08F2/38 ,  C08F293/005 ,  C08F2438/03 ,  C08G83/008

摘要： A design, synthesis and use of templated chemical routes are disclosed for the synthesis of interlocked macromolecular structures and orderly entanglements that are dubbed “Knotty Polymers” using combined supramolecularly assembled macroinitiators and living polymerization.

摘要翻译： 公开了模板化学路线的设计，合成和使用，用于合成联锁的大分子结构和有序缠结，其使用组合的超分子组装的大分子引发剂和活性聚合被称为“Knotty Polymers”。

公开(公告)号：US08640423B2

公开(公告)日：2014-02-04

申请号：US12874875

申请日：2010-09-02

申请人： Joseph Meppelink ,  Andrew Vrana ,  Chris Boyer

发明人： Joseph Meppelink ,  Andrew Vrana ,  Chris Boyer

IPC分类号： E04D5/00

CPC分类号： H02S20/23 ,  F24S25/11 ,  F24S25/16 ,  Y02B10/12 ,  Y02B10/20 ,  Y02E10/47 ,  Y10T29/49963

摘要： An apparatus for retaining a photovoltaic panel on a rooftop includes a vessel having a first side, second side, front, bottom, and top panels, wherein the panels are attached to define a void within the vessel. A fill port is disposed on the vessel. A first hole is adapted to receive a screw on the top panel, wherein the first hole is aligned with a second hole disposed on the bottom panel, wherein the first and second holes are adapted to be aligned with a third hole on a first mounting cross arm. The top panel is inclined at an angle relative to the bottom panel.

摘要翻译： 用于将太阳能电池板保持在屋顶上的装置包括具有第一侧面，第二侧面，前部，底部和顶部面板的容器，其中所述面板被附接以在容器内限定空隙。 填充口设置在容器上。 第一孔适于在顶板上容纳螺钉，其中第一孔与设置在底板上的第二孔对准，其中第一和第二孔适于与第一安装十字架上的第三孔对齐 臂。 顶板相对于底板倾斜一定角度。

公开(公告)号：US20130324738A1

公开(公告)日：2013-12-05

申请号：US13894101

申请日：2013-05-14

申请人： Chengzhi Cai ,  Guoting Qin ,  Amit Kumar

发明人： Chengzhi Cai ,  Guoting Qin ,  Amit Kumar

IPC分类号： C08F4/04

CPC分类号： C08F4/04 ,  A61K9/1271 ,  A61K9/1277 ,  A61K47/6911 ,  A61K47/6915 ,  A61K49/0002 ,  A61K49/0021 ,  A61K49/0043 ,  A61K49/0084 ,  B01J31/1815 ,  B01J2231/44 ,  B01J2531/16 ,  C08F30/02

摘要： According to some embodiments, the present invention provides compositions and methods for making and using multifunctional polymerized liposomes finding relevant application in medical sciences, particularly in bioimaging, diagnostics, drug delivery, and drug formulation. The compositions and methods involve lipids that are both polymerizable and have a “clickable” group that provides the ability to functionalize via a click reaction with various functional moieties useful for the above-listed applications.

公开(公告)号：US20130317360A1

公开(公告)日：2013-11-28

申请号：US13888083

申请日：2013-05-06

申请人： Pei-Herng Hor ,  Raja Muthupillai ,  Jiming Zhang

发明人： Pei-Herng Hor ,  Raja Muthupillai ,  Jiming Zhang

IPC分类号： A61M37/00

CPC分类号： A61M37/0092 ,  A61B5/0036 ,  A61B5/055 ,  A61N7/02 ,  G01R33/4804

摘要： In some embodiments, the present disclosure pertains to a method of delivery of an active agent to a target tissue, in a subject in need thereof comprising positioning a high intensity focused ultrasound transducer to enable delivery of ultrasound energy to the target tissue. Such a method comprises energizing the high intensity focused ultrasound transducer; imaging at least a portion of the target tissue; and discontinuing delivery of ultrasound energy. Further, such a method may comprise administering the active agent to the subject under the conditions of thermal stimulation. In another embodiment, the present disclosure relates to a method of treating a tumor in a subject in need thereof comprising administering a therapeutic agent to the subject and providing thermal stimulation to the tumor. In some embodiments, there is provided a method for increasing the efficacy of a therapeutic agent in a target tissue.

摘要翻译： 在一些实施方案中，本公开内容涉及在有需要的受试者中将活性剂递送至靶组织的方法，包括定位高强度聚焦超声换能器以能够将超声能量传递到靶组织。 这种方法包括激发高强度聚焦超声换能器; 成像至少一部分目标组织; 并停止提供超声能量。 此外，这种方法可以包括在热刺激的条件下向受试者施用活性剂。 在另一个实施方案中，本公开涉及治疗有需要的受试者的肿瘤的方法，包括向受试者施用治疗剂并向肿瘤提供热刺激。 在一些实施方案中，提供了用于增加治疗剂在靶组织中的功效的方法。

公开(公告)号：US08575112B2

公开(公告)日：2013-11-05

申请号：US12807900

申请日：2010-09-16

申请人： Stuart E. Dryer

发明人： Stuart E. Dryer

IPC分类号： A61K38/08

CPC分类号： C07K7/06 ,  A61K38/00 ,  C07K2319/10

摘要： Provided herein are peptide modulators of ion channels. Specifically, the peptide modulators comprise the amino acid sequence VEDEC wherein V is valine, E is glutamate, D is aspartate, C is cysteine. In certain embodiments, the modulator is attached to the C-terminal end of Slo1 protein isoform. The present invention also claims conjugations of the first valine that make the peptide modulator more membrane permeable, such as myristoyl moieties and arginine-rich cell penetrating peptides. The present invention contemplates use of the peptide modulators in the treatment of diseases/malfunctions such as epilepsy, chronic pain, migraine, asthma, chronic obstructive pulmonary disease, urinary incontinence, hypertension, erectile dysfunction, irritable bowel syndrome, renal disorders of electrolyte imbalance, and possibly in certain kinds of cancer.

摘要翻译： 本文提供了离子通道的肽调节剂。 具体地说，肽调节剂包含氨基酸序列VEDEC，其中V是缬氨酸，E是谷氨酸，D是天冬氨酸，C是半胱氨酸。 在某些实施方案中，调节剂连接到Slo1蛋白质同种型的C末端。 本发明还要求使第一缬氨酸的缀合使肽调节剂更可透膜，例如肉豆蔻酰部分和富含精氨酸的细胞穿透肽。 本发明考虑使用肽调节剂来治疗诸如癫痫，慢性疼痛，偏头痛，哮喘，慢性阻塞性肺病，尿失禁，高血压，勃起功能障碍，肠易激综合征，电解质不平衡的肾脏疾病等疾病/功能障碍， 并可能在某些种类的癌症。

公开(公告)号：US20130240437A1

公开(公告)日：2013-09-19

申请号：US13609179

申请日：2012-09-10

申请人： Debora F. Rodrigues ,  Rigoberto C Advincula ,  Fritz Claydon ,  Catherine M. Santos ,  Maria Celeste R. Tria

发明人： Debora F. Rodrigues ,  Rigoberto C Advincula ,  Fritz Claydon ,  Catherine M. Santos ,  Maria Celeste R. Tria

IPC分类号： B01D71/28

CPC分类号： B01D69/148 ,  B01D67/0079 ,  B01D69/02 ,  B01D69/12 ,  B01D69/147 ,  B01D71/021 ,  B01D71/28 ,  B01D71/82 ,  B01D2323/36 ,  B01D2323/46 ,  B01D2323/48 ,  B01D2325/12 ,  B01D2325/48 ,  Y10S977/734 ,  Y10S977/753 ,  Y10S977/847

摘要： The disclosed subject matter provides a filter that is modified by a polymer-carbon based nanomaterial nanocomposite intended to significantly enhance the performance of filtration, separation, and remediation of a broad variety of chemicals, heavy metal ions, organic matters, and living organisms. Polymeric materials, such as but not limited to poly-N-vinyl carbazole (PVK), are combined with (1) graphene (G) and/or graphene-like materials based nanomaterials and (2) graphene oxide (GO) chemically modified with a chelating agent such as but not limited to EDTA. The nanocomposite is homogenously deposited on the surface of the membrane.