公开(公告)号：US12090245B2

公开(公告)日：2024-09-17

申请号：US18144859

申请日：2023-05-09

Applicant: SOUTH CHINA UNIVERSITY OF TECHNOLOGY

Inventor： Xuetao Shi ,  Wei Yang

IPC: A61L24/06 ,  C08G83/00 ,  C08L29/04 ,  A61L24/00

CPC classification number: A61L24/06 ,  C08G83/008 ,  C08L29/04 ,  A61L24/0015 ,  C08G2170/00 ,  C08L2203/02 ,  C08L2203/162

Abstract: A tissue adhesive membrane and a preparation method thereof are provided. The tissue adhesive membrane includes a supramolecular polymer and an enhancer; the supramolecular polymer is prepared by copolymerization of lipoic acid and a biocompatible stabilizer; and the enhancer includes at least one selected from the group consisting of a cationic compound, a cationic polymer, and a metal particle. The tissue adhesive membrane of the present invention can achieve rapid adhesion, seal wounds continuously and effectively, and maintain long-lasting mechanical strength. The components of the tissue adhesive membrane come from natural components of animals and plants, have good biocompatibility, and possess the functions of antibacterial and inhibiting inflammation. The tissue adhesive membrane of the present invention is a hydrophobic adhesive membrane where hydrogen bonding and high surface energy can provide strong adhesion energy and no adverse active groups that may cause irritation or discomfort are contained.

公开(公告)号：US20240287259A1

公开(公告)日：2024-08-29

申请号：US18427583

申请日：2024-01-30

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Julia A. KORNFIELD ,  Ming-Hsin WEI

IPC: C08G83/00 ,  C08G61/08 ,  C08K5/00 ,  C08L101/02 ,  C08L101/08 ,  C10L1/16 ,  C10L1/195 ,  C10L1/236 ,  C10L10/02 ,  C10L10/08 ,  F17D1/17

CPC classification number: C08G83/005 ,  C08G61/08 ,  C08G83/00 ,  C08G83/008 ,  C08K5/0008 ,  C08L101/02 ,  C08L101/025 ,  C08L101/08 ,  C10L1/1658 ,  C10L1/195 ,  C10L1/236 ,  C10L10/02 ,  C10L10/08 ,  F17D1/17 ,  C08F2438/01 ,  C08G2261/132 ,  C08G2261/1644 ,  C08G2261/3323 ,  C08G2261/418 ,  C08G2261/63 ,  C08G2261/64 ,  C08G2261/72 ,  C10L2230/22 ,  C10L2250/04

Abstract: Described herein are associative polymers capable of controlling a physical and/or chemical property of non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms.

公开(公告)号：US20240209158A1

公开(公告)日：2024-06-27

申请号：US17907696

申请日：2021-06-23

Applicant: Zhejiang University

Inventor： Pintong Huang ,  Tao Zhang ,  Chao Zhang ,  Xue Wang ,  Jiawei Tu

IPC: C08G83/00

CPC classification number: C08G83/008

Abstract: The invention provides an ultra-small nano metal organic framework material and a preparation method thereof. The MOFs material is prepared from a low-cost metal source and organic ligands through solvothermal reaction, wherein metal ions in the metal source are at least two of ferric ions, bivalent copper ions or bivalent zinc ions; the ligands are at least two of terephthalic acid, 2-aminoterephthalic acid, meso-tetra (4-carboxyphenyl) porphin, 2-nitroterephthalic acid, 2-hydroxyterephthalic acid and trimesic acid; the solvent is formed by mixing ethanol and o-dichlorobenzene according to the volume ratio of (1-3):1. The particle size of the prepared MOFs material is 2-10 nm, and the prepared MOFs material is high in dispersity, specific surface area and activity. The MOFs material aqueous solution can generate a large amount of active oxygen in an ultrasonic environment, and has extremely high medical value.

公开(公告)号：US20240139722A1

公开(公告)日：2024-05-02

申请号：US18495958

申请日：2023-10-27

Applicant: The Johns Hopkins University

Inventor： Michael TSAPATSIS ,  Efrosini KOKKOLI ,  Danyu WANG

IPC: B01J31/16 ,  C08G83/00

CPC classification number: B01J31/1691 ,  C08G83/008 ,  B01J2231/326 ,  B01J2231/348 ,  B01J2231/4205

Abstract: Disclosed is a method to modify metal-organic frameworks (MOFs) by irreversible adsorption of nucleotides including, but not limited to, adenosine triphosphate (ATP), guanosine triphosphate (GTP), deoxyadenosine triphosphate (dATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP), the modified MOFs, and the use of the modified MOFs as adsorbents and catalysts.

公开(公告)号：US11891406B2

公开(公告)日：2024-02-06

申请号：US16561515

申请日：2019-09-05

Applicant: King Fahd University of Petroleum and Minerals

Inventor： Abdul Malik P. Peedikakkal ,  Abdul-Rahman Al-Betar ,  Ammar Hussain Al-Mousa

IPC: C07F3/00 ,  C07F3/06 ,  C08L79/02 ,  H01G11/48 ,  C08G83/00 ,  H01M4/60

CPC classification number: C07F3/003 ,  C08G83/008 ,  C08L79/02 ,  H01G11/48 ,  H01M4/606

Abstract: A method for enhancing the conductivity of MOF-5 by the development of an MOF-5 polymer composite material. The composite material incorporates a conductive polymer, preferably polyaniline, in the solvo-thermal synthesis pathway of MOF-5. The electrically conductive MOF-5 composite exhibits electric conductivity three orders of magnitude higher than that of MOF-5 while maintaining the crystallinity, robustness, and thermal stability of MOF-5.

公开(公告)号：US11879038B2

公开(公告)日：2024-01-23

申请号：US17637722

申请日：2020-09-09

Applicant: UNIVERSITÉ DE STRASBOURG ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

Inventor： Loïc Jierry ,  Christophe Serra ,  Pierre Schaaf ,  Jennifer Rodon Fores ,  Fouzia Boulmedais

IPC: C08J3/075 ,  C08G83/00 ,  C08J9/40

CPC classification number: C08G83/008 ,  C08J3/075 ,  C08J9/405 ,  C08J2205/05 ,  C08J2361/28 ,  C08J2489/00

Abstract: The present invention relates to a polymer foam, said polymer foam comprising pores forming an open-cell polymer foam, said polymer foam comprising a supramolecular gel inside pores, and said polymer foam comprising at least one enzyme. The present invention relates to a supramolecular gel; its preparation and its applications, notably in chemical synthesis and kinetic resolution, in particular of organic compounds. The present invention also relates to flow chemistry.

公开(公告)号：US11725082B2

公开(公告)日：2023-08-15

申请号：US17617084

申请日：2020-07-15

Applicant: SOLVAY SPECIALTY POLYMERS ITALY S.P.A. ,  POLITECNICO DI MILANO

Inventor： Claudio Adolfo Pietro Tonelli ,  Floryan De Campo ,  Antonio Mattia Grande

IPC: C08G83/00 ,  F16F15/023 ,  F16F15/04

CPC classification number: C08G83/008 ,  F16F15/023 ,  F16F15/04 ,  F16F2224/04

Abstract: The invention relates to a method for attenuating vibrations and/or shocks, said method comprising providing a damper assembly which comprises a moving part and a supramolecular polymer in contact with said moving part, and exposing said moving part to said vibrations and/or shocks, wherein said supramolecular polymer is obtained by reacting: at least one first polymer [polymer (P1)] comprising a polymer chain [chain (R)] consisting of a plurality of non-ionisable recurring units [units (U)], said polymer (P1) having two chain ends (E1, E1′), each end comprising at least one ionisable acid group, and at least one second polymer [polymer (P2)] comprising a polymer chain [chain (R)] consisting of a plurality of recurring units [units (U)], said chain (R) being equal to or different from that of polymer (P1), and said polymer (P2) having two chain ends (E2, E2′), each end comprising at least one ionisable amino group.

公开(公告)号：US20230235127A1

公开(公告)日：2023-07-27

申请号：US17894559

申请日：2022-08-24

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Julia A. KORNFIELD ,  Ming-Hsin WEI

IPC: C08G83/00 ,  C08L101/02 ,  C10L1/16 ,  C10L1/236 ,  C08L101/08 ,  F17D1/17 ,  C08G61/08 ,  C10L10/02 ,  C08K5/00 ,  C10L1/195 ,  C10L10/08

CPC classification number: C08G83/005 ,  C08G83/00 ,  C08L101/02 ,  C08G83/008 ,  C10L1/1658 ,  C10L1/236 ,  C08L101/025 ,  C08L101/08 ,  F17D1/17 ,  C08G61/08 ,  C10L10/02 ,  C08K5/0008 ,  C10L1/195 ,  C10L10/08 ,  C08F2438/01 ,  C08G2261/132 ,  C08G2261/1644 ,  C08G2261/3323 ,  C08G2261/418 ,  C08G2261/63 ,  C08G2261/64 ,  C08G2261/72 ,  C10L2230/22 ,  C10L2250/04

Abstract: Described herein are associative polymers capable of controlling a physical and/or chemical property of non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms.

公开(公告)号：US11697715B2

公开(公告)日：2023-07-11

申请号：US17861772

申请日：2022-07-11

Applicant: Oren Scherman ,  Ji Liu

Inventor： Oren Scherman ,  Ji Liu

IPC: C08G83/00 ,  C08G73/06 ,  C08J3/075 ,  C08J3/24 ,  A61K47/58 ,  A61L24/04 ,  A61L24/00

CPC classification number: C08G83/008 ,  A61K47/58 ,  A61L24/043 ,  C08G73/06 ,  C08G83/007 ,  C08J3/075 ,  C08J3/246 ,  A61L24/0031 ,  C08J2379/04

Abstract: The invention provides a polymerizable composition and a hydrogel obtained or obtainable from the polymerizable composition. The polymerizable composition comprises cucurbituril and a first monomer having a guest for the cucurbituril, wherein the total monomer concentration, Cmon, within the polymerizable composition is at least 0.5 M. The composition may be an aqueous composition.

公开(公告)号：US20180221277A1

公开(公告)日：2018-08-09

申请号：US15807185

申请日：2017-11-08

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

Inventor： Seungpyo Hong ,  Yang Yang

IPC: A61K9/107 ,  C08G83/00 ,  A61K31/138 ,  A61K47/34 ,  C08G63/664 ,  A61K47/10 ,  A61K9/00 ,  C08G63/685

CPC classification number: A61K9/1075 ,  A61K9/0014 ,  A61K31/138 ,  A61K47/10 ,  A61K47/34 ,  C08G63/664 ,  C08G63/6852 ,  C08G83/004 ,  C08G83/008

Abstract: The invention generally relates to the field of drug delivery. In particular, the invention relates to amphiphilic dendron-coils, micelles thereof and their use for the transdermal delivery of drugs.