公开(公告)号：US5287079A

公开(公告)日：1994-02-15

申请号：US973790

申请日：1992-11-09

Applicant: Angelina M. Bernardi ,  James Cook ,  Leon Gurevich ,  Ronald Peterson

Inventor： Angelina M. Bernardi ,  James Cook ,  Leon Gurevich ,  Ronald Peterson

IPC: H01H85/00 ,  H01H85/041 ,  H01H85/143 ,  H01H85/175 ,  H01H85/43 ,  H01H85/02

CPC classification number: H01H85/0417 ,  H01H2085/0412 ,  H01H85/0082 ,  H01H85/143 ,  H01H85/1755 ,  H01H85/43

Abstract: There is provided a fast acting subminiature cylindrical fuse having a cylindrical cover substantially locked onto a cylindrical base. The locking mechanism for the cover comprises a plurality of grooves and a plurality of corresponding projections on the internal surface of the cover and the external surface of the fuse base. The lock projections have a relatively straight diverging upper surface and a rounded bottom locking surface. The fuse base has a spacing ridge on the bottom thereof that spaces the fuse bottom surface above a circuit board surface. The fuse also has a plurality of pressure relieving passageways extending from inside the fuse to the outside of the fuse.

Abstract translation: 提供了一种快速作用的超小型圆柱形保险丝，其具有基本锁定在圆柱形基座上的圆柱形盖。 盖的锁定机构包括多个凹槽和在盖的内表面和熔断器基座的外表面上的多个对应的突起。 锁定突起具有相对直的发散的上表面和圆形的底部锁定表面。 保险丝座在其底部具有间隔脊，其将保险丝底表面置于电路板表面之上。 保险丝还具有从保险丝内部延伸到保险丝外部的多个减压通路。

公开(公告)号：US4647533A

公开(公告)日：1987-03-03

申请号：US650739

申请日：1984-09-14

Applicant: David M. Weller ,  R. James Cook ,  J. Ole Becker

Inventor： David M. Weller ,  R. James Cook ,  J. Ole Becker

IPC: A01N63/00 ,  C12Q1/02 ,  C12Q1/24 ,  C12R1/39 ,  C12R1/40

CPC classification number: C12R1/38 ,  A01N63/00 ,  C12Q1/02 ,  Y10S435/876 ,  Y10S435/877

Abstract: A method for screening bacteria to select strains which will suppress Pythium spp. in small grain crops under field conditions and a method for applying field-suppressive bacteria to suppress Pythium spp. in a commercial setting are described. Four Pseudomonas strains which passed the screen test are disclosed.

Abstract translation: 筛选细菌以选择将抑制腐霉属的菌株的方法。 在田间条件下的小粮食作物和一种应用场抑制细菌抑制腐霉属的方法。 在商业设置中进行描述。 披露了通过筛选试验的四种假单胞菌菌株。

公开(公告)号：US2400766A

公开(公告)日：1946-05-21

申请号：US54874244

申请日：1944-08-09

Applicant: MCSPADDEN DONOVAN M ,  JAMES COOK

Inventor： MCSPADDEN DONOVAN M ,  JAMES COOK

IPC: D06C3/06

CPC classification number: D06C3/065 ,  Y10T24/44769

公开(公告)号：US697725A

公开(公告)日：1902-04-15

申请号：US1901069145

申请日：1901-07-20

Applicant: JONES JAMES COOK

Inventor： JONES JAMES COOK

CPC classification number: A47B88/20 ,  A47B88/90 ,  B65D43/22

公开(公告)号：US20240400649A1

公开(公告)日：2024-12-05

申请号：US18414112

申请日：2024-01-16

Applicant: James Cook University

Inventor： Alex Loukas ,  Andrew Leech ,  Darren Pickering

IPC: C07K14/81 ,  A61K38/00 ,  A61K38/57 ,  A61K45/06 ,  C07K14/435

Abstract: A modified Ac-TMP-2 protein lacks one or a plurality of acidic C-terminal amino acids normally present in a full-length or wild-type Ac-TMP-2 protein and may also lack one or a plurality of N-terminal amino acids while retaining the amino acid sequence C-S-C at or near the N-terminus. The modified Ac-TMP-2 protein may be useful in method and composition for reducing or alleviating inflammation in a subject. Inflammation may be associated with a disease is a disease of the digestive tract such as chronic gastritis or an inflammatory bowel disease such as Crohn's disease or ulcerative colitis, or a disease of the respiratory system, such as asthma, emphysema, chronic bronchitis, and chronic obstructive pulmonary disease.

公开(公告)号：US20240174719A1

公开(公告)日：2024-05-30

申请号：US18550807

申请日：2022-03-17

Applicant: James Cook University

Inventor： Alexander Constantine Loukas ,  Paul Robert Giacomin ,  Stephanie Margaret Ryan ,  Roland Ruscher

IPC: C07K14/00 ,  A61P37/06 ,  C12N15/63

CPC classification number: C07K14/001 ,  A61P37/06 ,  C12N15/63

Abstract: The present invention relates to proteins suitable for treating or preventing an inflammatory or autoimmune condition, pharmaceutical compositions comprising same, and methods of use comprising same.

公开(公告)号：US10822395B2

公开(公告)日：2020-11-03

申请号：US15023165

申请日：2014-09-18

Applicant: James Cook University

Inventor： Alex Loukas ,  Andrew Leech ,  Darren Pickering

IPC: A61K38/00 ,  A61P29/00 ,  A61K38/16 ,  A61P11/06 ,  C07K14/81 ,  A61K45/06 ,  C07K14/435 ,  A61K38/57

Abstract: A modified Ac-TMP-2 protein lacks one or a plurality of acidic C-terminal amino acids normally present in a full-length or wild-type Ac-TMP-2 protein and may also lack one or a plurality of N-terminal amino acids while retaining the amino acid sequence C—S—C at or near the N-terminus. The modified Ac-TMP-2 protein may be useful in method and composition for reducing or alleviating inflammation in a subject. Inflammation may be associated with a disease is a disease of the digestive tract such as chronic gastritis or an inflammatory bowel disease such as Crohn's disease or ulcerative colitis, or a disease of the respiratory system, such as asthma, emphysema, chronic bronchitis, and chronic obstructive pulmonary disease.

公开(公告)号：US20190194279A1

公开(公告)日：2019-06-27

申请号：US16329800

申请日：2017-09-04

Applicant: James Cook University

Inventor： Alex Loukas ,  Michael Smout ,  Norelle Daly

IPC: C07K14/475 ,  A61P17/02

CPC classification number: C07K14/475 ,  A61K38/00 ,  A61P17/02 ,  A61P43/00

Abstract: Peptides derived from the N-terminal region of granulin have activity in promoting cell proliferation, migration and/or wound healing. Furthermore, an additional disulphide bond may be engineered into such peptides to improve or otherwise modify the folding of the peptide. The peptides may also be modified such as at proline residues improve the ability of the peptide to promote cell proliferation.

公开(公告)号：US20190174793A1

公开(公告)日：2019-06-13

申请号：US16321070

申请日：2016-07-29

Applicant: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION ,  MEAT & LIVESTOCK AUSTRALIA LIMITED ,  JAMES COOK UNIVERSITY

Inventor： Nigel William TOMKINS ,  Rocky DE NYS ,  Robert Douglas KINLEY ,  Marie Elisabeth MAGNUSSON ,  Lorenna MACHADO ,  Nicholas Andrew PAUL

IPC: A23K10/30 ,  A23K50/10 ,  A23K40/20

Abstract: The invention relates to utilising red marine macroalgae to provide improvements in growth performance of livestock, particularly ruminant animals for red meat production, especially cattle, in pasture and feedlot farming systems. There is provided a method for improving the growth performance of a livestock animal in a farming system including: providing a red marine macroalgae to a farming system to enable consumption of the red marine macroalgae by a livestock animal in the farming system; thereby improving the growth performance of the livestock animal in the system.

公开(公告)号：US09637527B2

公开(公告)日：2017-05-02

申请号：US14384681

申请日：2013-03-13

Applicant: JAMES COOK UNIVERSITY

Inventor： Alex Loukas ,  Severine Navarro

IPC: C07K14/435 ,  A61K38/57 ,  A61K39/00 ,  A61K45/06

CPC classification number: C07K14/4354 ,  A61K38/57 ,  A61K39/0003 ,  A61K45/06

Abstract: A method for reducing or alleviating inflammation in a subject includes administering to the subject a therapeutically effective amount of: (a) Ac-TMP-1 or a biologically active fragment or variant of Ac-TMP-1; (b) Ac-TMP-2 or a biologically active fragment or variant of Ac-TMP-2; or (c) a combination of (a) and (b), to thereby reduce or alleviate inflammation in the subject. A method for preventing or treating asthma or inflammatory bowel disease in a subject includes administering to the subject a therapeutically effective amount of: (a) Ac-TMP-1 or a biologically active fragment or variant of Ac-TMP-1; (b) Ac-TMP-2 or a biologically active fragment or variant of Ac-TMP-2; or (c) a combination of (a) and (b), to thereby prevent or treat asthma or inflammatory bowel disease in the subject. The subject may be a mammal, inclusive of humans.