公开(公告)号：US06213982B1

公开(公告)日：2001-04-10

申请号：US09478432

申请日：2000-01-06

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61M5178

CPC classification number: B05B11/3011 ,  A61F9/0026 ,  A61M11/00 ,  B05B11/3076 ,  B05B11/3092 ,  B05B11/3095

Abstract: A medicament-dispensing system includes a cartridge for housing and actuating an accordion-like vial-dispenser for dispensing a calibrated amount of medicament by means of a single actuation motion which sequentially loads the vial-dispenser and dispenses the loaded medicament. The vial-dispenser has a front bellows portion, a rear bellows portion, an internal piston mechanism, a medicament storage chamber and a dosage cavity. The cartridge has a trigger mechanism which acts in concert with a notched lever and a wedge-shaped arm internally located in the cartridge to sequentially load the dosage cavity with medicament and discharge it. Depression of the trigger mechanism simultaneously extends, by means of the notched lever, the front bellows portion and compresses the rear bellows portion to load the dosage cavity with medicament. Once the notched lever has extended the front bellows portion a predetermined distance, the notched lever is disengaged from the front bellows portion by the wedge-shaped arm extending from the rear wall of the housing, thereby releasing the front and rear bellows portions, along with the internal piston mechanism, to return to original position and force the medicament from the dosage cavity via a nozzle of the vial-dispenser.

Abstract translation: 药物分配系统包括用于容纳和致动手风琴式小瓶 - 分配器的药筒，用于通过单次致动运动分配校准量的药物，其顺序地加载小瓶分配器并分配装载的药物。 小瓶分配器具有前波纹管部分，后波纹管部分，内部活塞机构，药物储存室和剂量腔。 药筒具有触发器机构，其与位于药筒内部的缺口杠杆和楔形臂协同作用，以顺序地将药物腔装入药物并将其排出。 触发机构的凹陷同时通过切口杆延伸前波纹管部分并压缩后波纹管部分以用药物装载剂量腔。 一旦切口杆将前波纹管部分延伸了预定的距离，则切口杆通过从壳体的后壁延伸的楔形臂与前波纹管部分分离，从而释放前波纹管部分和后波纹管部分以及 内部活塞机构返回到初始位置，并且通过小瓶分配器的喷嘴迫使药物从剂量腔中。

公开(公告)号：US5816772A

公开(公告)日：1998-10-06

申请号：US705354

申请日：1996-08-29

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61G10/00 ,  B01L1/02 ,  B65G65/00

CPC classification number: A61G10/005 ,  B01L1/02 ,  A61G2205/10

Abstract: Method of transferring articles (1) contained in a closed transfer pocket (4) into an enclosure, wherein a part S of the wall of the closed transfer pocket (4) is stuck onto a part of the enclosure, there is cut out in the said part S, and from the inside of the enclosure, an opening of sufficient area to allow the passage of the said articles (1), the periphery of the opening of the transfer pocket (4) remaining stuck to the enclosure, and a corresponding opening (13) is made in the enclosure and the said articles (1) are then transferred into the enclosure through the said openings, pocket and enclosure for sterile transfer in particular.

Abstract translation: 将包含在封闭的传送袋（4）中的物品（1）转移到外壳中的方法，其中封闭传送袋（4）的壁的部分S粘附到外壳的一部分上， 所述部分S，并且从所述外壳的内部开放足够的面积以允许所述物品（1）通过，所述传送袋（4）的所述开口的周边保持粘附到所述外壳，并且相应地 在外壳中形成开口（13），然后通过所述开口，口袋和外壳将所述物品（1）转移到外壳中，特别是用于无菌转移。

公开(公告)号：USD374719S

公开(公告)日：1996-10-15

申请号：US40633

申请日：1995-06-22

Applicant: Daniel Py

Designer： Daniel Py

公开(公告)号：US5267986A

公开(公告)日：1993-12-07

申请号：US863943

申请日：1992-04-06

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61J1/05 ,  A61F2/00 ,  A61F9/00 ,  A61M11/00 ,  A61M35/00

CPC classification number: A61F9/0026 ,  A61F9/0008 ,  A61F2250/0067

Abstract: A cartridge for actuating a piston-like or accordion-like dispenser-vial for applying medicament to an eye. The cartridge includes a housing for holding the dispenser-vial and a telescoping cylinder for compressing the dispenser-vial in the longitudinal direction to actuate the vial. The cartridge includes a locking mechanism for locking the telescoping cylinder to restrict its movement and a trigger mechanism for releasing the cylinder from the locked position so that a drop is released from the dispenser. The housing includes a finger for engaging the lower eyelid and exposing the conjunctival cul de sac.

Abstract translation: 用于致动用于将药物施用于眼睛的活塞式或类风琴式分配器 - 小瓶的药筒。 该盒包括用于保持分配器 - 小瓶的壳体和用于在纵向方向上压缩分配器 - 小瓶以致动小瓶的伸缩圆柱体。 该卡盘包括用于锁定伸缩缸以限制其运动的锁定机构和用于将汽缸从锁定位置释放的触发机构，使得液滴从分配器释放。 外壳包括用于接合下眼睑并暴露结膜cul囊的手指。

公开(公告)号：US09731956B2

公开(公告)日：2017-08-15

申请号：US14811330

申请日：2015-07-28

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B67D3/04 ,  B67B7/00

CPC classification number: B67D3/043 ,  B67B7/24

Abstract: A pouch connector includes a safety cap having a cap base portion and a main connector disposed opposite the safety cap. The main connector and safety cap are configured to receive a portion of a pouch therebetween. The main connector includes a piercing member for piercing the pouch, an actuating portion for actuating the piercing member and a main connector base portion. The piercing member is configured to pierce through a portion of the pouch so as to provide fluid communication between a substance inside the pouch and the interior of the main connector. A polymeric membrane is coupled to at least one of the cap base portion and the main connector base portion.

公开(公告)号：US20170202741A1

公开(公告)日：2017-07-20

申请号：US15410762

申请日：2017-01-19

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61J1/20

Abstract: Connector assembly including a piercing member having a flow port therein attached to a first piece, with the piercing member slidingly receivable within a second piece, wherein the piercing member and the second pierce are movable relative to each other between a first position where the second pieces closes the flow port and a second position where the flow port is open. The first piece contains a locking mechanism that lockingly engages with a device when connected thereto, preventing subsequent disconnection of first piece and the device. Upon initial connection of the first piece to the device, the second piece is moved from the first position to the second position.

公开(公告)号：US09440773B2

公开(公告)日：2016-09-13

申请号：US13572310

申请日：2012-08-10

Applicant: Daniel Py ,  Julian V. Chan ,  Giovanni Rodriguez

Inventor： Daniel Py ,  Julian V. Chan ,  Giovanni Rodriguez

IPC: B67C3/00 ,  B65D35/28 ,  A45D34/04 ,  A45D34/00

CPC classification number: B65D35/28 ,  A45D34/04 ,  A45D2034/007 ,  A45D2200/055

Abstract: A dispenser for dispensing a substance, such as a liquid lipstick or other cosmetic, pharmaceutical or cosmeceutical product, has a body with a variable-volume storage chamber for storing the product. A dispensing portion is connected with the body and a one-way valve for dispensing amounts of product therethrough. The dispensing portion defines a compression chamber in fluid communication with the storage chamber for receiving product therefrom, and an outlet aperture coupled in fluid communication with the compression chamber. The one-way valve has a valve seat, and a visco-elastic valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat, and the seam is connectable in fluid communication with the outlet aperture to allow the passage of product through the seam and out of the dispenser. An actuator is drivingly connected to the compression chamber for pressurizing product within the compression chamber and dispensing an amount of product within the compression chamber.

Abstract translation: 用于分配物质的分配器，例如液体口红或其它化妆品，药​​物或药妆产品，具有具有用于存储产品的可变容积储存室的主体。 分配部分与主体连接，单向阀用于分配产品的数量。 分配部分限定与储存室流体连通的压缩室，用于从其中接收产品，以及与压缩室流体连通的出口孔。 单向阀具有阀座和安置在阀座上的粘弹性阀盖，并且在其间形成常闭的轴向延伸的接缝，形成在阀盖和阀座之间的流体密封。 柔性阀盖可相对于阀座移动，并且接缝可与出口孔流体连通以允许产品通过接缝并从分配器中通过。 致动器驱动地连接到压缩室，用于对压缩室内的产品进行加压，并且在压缩室内分配一定数量的产品。

公开(公告)号：US20160068283A1

公开(公告)日：2016-03-10

申请号：US14824041

申请日：2015-08-11

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B3/02 ,  B29C65/00 ,  B65B55/10 ,  B65B55/08 ,  B65B7/16 ,  B29C45/00 ,  B65B3/00

CPC classification number: B65B3/022 ,  B29C45/006 ,  B29C2791/005 ,  B29K2023/00 ,  B29L2031/565 ,  B65B3/003 ,  B65B7/16 ,  B65B51/10 ,  B65B55/08 ,  B65B55/10

Abstract: A stopper and container body are molded in the same molding machine. An assembly device, such as a pick and place robot, transfers the stopper from one mold cavity into the opening in the container body located within another mold cavity, or vice versa, to assemble the stopper and container body. Then, the assembled container body and stopper are removed from the molding machine and transported to a needle filling and laser resealing station for filling and laser resealing. A laminar flow source directs a substantially laminar flow of air or sterile gas over the mold surfaces, stoppers and container bodies, and assembly device, to prevent contamination during assembly.

Abstract translation: 塞子和容器主体在相同的成型机中成型。 诸如拾放机器人的组装装置将止动器从一个模腔转移到位于另一个模腔内的容器主体中的开口中，反之亦然，以组装止动器和容器主体。 然后，将组装的容器主体和止动件从成型机中取出并输送到针填充和激光重新密封站，用于填充和激光重新密封。 层流源将空气或无菌气体的基本层流引导到模具表面，塞子和容器主体以及组装装置上，以防止组装过程中的污染。

公开(公告)号：US09222728B2

公开(公告)日：2015-12-29

申请号：US11789498

申请日：2007-04-24

Applicant: Daniel Py

Inventor： Daniel Py

IPC: F26B5/06

CPC classification number: F26B5/06

Abstract: A device and related method are provided for lyophilizing a substance within the device and storing therein the lyophilized substance. The device is penetrable by a needle for filling the device with the substance to be lyophilized, and a resulting needle hole in the device is laser resealable by transmitting thereon laser radiation from a laser source. The device defines a chamber for receiving therein the substance to be lyophilized. A needle penetrable and laser resealable portion of the device is pierceable with a needle to form a needle aperture therethrough to fill the chamber with the substance to be lyophilized through the needle, and is laser resealable to hermetically seal the needle aperture by applying laser radiation thereto. A filter is connectable in fluid communication between an interior and exterior of the chamber for permitting fluid to flow therethrough in a direction from the interior to the exterior of the chamber, and for substantially preventing contaminants from flowing therethrough in a direction from the exterior to the interior of the chamber.

Abstract translation: 提供了一种装置和相关方法，用于冻结装置内的物质并将其中的冻干物质储存在其中。 该装置可以用针将待冷冻干燥的物质填充到装置上，并且通过从激光源发射激光辐射来激光重新密封该装置中的针孔。 该装置限定用于在其中接收待冻干物质的室。 装置的针穿透和可激光重新密封部分可用针刺穿以形成穿过其中的针孔，以通过针将待冷冻干燥的物质填充到腔室中，并且通过施加激光辐射可激光重新密封以密封针孔 。 过滤器可连接在室的内部和外部之间的流体连通中，以允许流体从腔室的内部到外部的方向流过其中，并且用于基本上防止污染物沿着从外部到外部的方向流过 室内

公开(公告)号：USRE45589E1

公开(公告)日：2015-06-30

申请号：US13454853

申请日：2012-04-24

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B05B11/00

CPC classification number: B05B11/3011 ,  A61F9/0026 ,  A61M11/00 ,  B05B11/3076 ,  B05B11/3092 ,  B05B11/3095

Abstract: A medicament-dispensing system includes a cartridge for housing and actuating an accordion-like vial-dispenser for dispensing a calibrated amount of medicament by means of a single actuation motion which sequentially loads the vial-dispenser and dispenses the loaded medicament. The vial-dispenser has a front bellows portion, a rear bellows portion, an internal piston mechanism, a medicament storage chamber and a dosage cavity. The cartridge has a trigger mechanism which acts in concert with a notched lever and a wedge-shaped arm internally located in the cartridge to sequentially load the dosage cavity with medicament and discharge it. Depression of the trigger mechanism simultaneously extends, by means of the notched lever, the front bellows portion and compresses the rear bellows portion to load the dosage cavity with medicament. Once the notched lever has extended the front bellows portion a predetermined distance, the notched lever is disengaged from the front bellows portion by the wedge-shaped arm extending from the rear wall of the housing, thereby releasing the front and rear bellows portions, along with the internal piston mechanism, to return to original position and force the medicament from the dosage cavity via a nozzle of the vial-dispenser.

Abstract translation: 药物分配系统包括用于容纳和致动手风琴式小瓶 - 分配器的药筒，用于通过单次致动运动分配校准量的药物，其顺序地加载小瓶分配器并分配装载的药物。 小瓶分配器具有前波纹管部分，后波纹管部分，内部活塞机构，药物储存室和剂量腔。 药筒具有触发器机构，其与位于药筒内部的缺口杠杆和楔形臂协同作用，以顺序地将药物腔装入药物并将其排出。 触发机构的凹陷同时通过切口杆延伸前波纹管部分并压缩后波纹管部分以用药物装载剂量腔。 一旦切口杆将前波纹管部分延伸了预定的距离，则切口杆通过从壳体的后壁延伸的楔形臂与前波纹管部分分离，从而释放前波纹管部分和后波纹管部分以及 内部活塞机构返回到初始位置，并且通过小瓶分配器的喷嘴迫使药物从剂量腔中。