公开(公告)号：US20250010080A1

公开(公告)日：2025-01-09

申请号：US18894301

申请日：2024-09-24

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Jeffrey M. Gillberg ,  Robert W. Stadler

IPC: A61N1/368 ,  A61B5/00 ,  A61B5/02 ,  A61B5/05 ,  A61B5/282 ,  A61B5/316 ,  A61B5/318 ,  A61B5/339 ,  A61B5/349 ,  A61N1/04 ,  A61N1/362

Abstract: Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.

公开(公告)号：US12172021B2

公开(公告)日：2024-12-24

申请号：US17559092

申请日：2021-12-22

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/37 ,  A61N1/05 ,  A61N1/365 ,  A61N1/368

Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.

公开(公告)号：US20240189605A1

公开(公告)日：2024-06-13

申请号：US18583399

申请日：2024-02-21

Applicant: MEDTRONIC, INC.

Inventor： Richard M.T. Lu ,  Subham Ghosh ,  Robert W. Stadler

IPC: A61N1/37 ,  A61B5/361 ,  A61N1/362 ,  A61N1/368

CPC classification number: A61N1/371 ,  A61B5/361 ,  A61N1/3624 ,  A61N1/36842 ,  A61N1/3716 ,  A61N1/3622 ,  A61N1/3684 ,  A61N1/36843

Abstract: The present disclosure pertains to cardiac pacing methods and systems, and, more particularly, to cardiac resynchronization therapy (CRT). In particular, the present disclosure pertains to determining whether a patient is experiencing atrial fibrillation (AF). If the patient is experiencing AF, the efficacy of CRT is determined. A signal is sensed in response to a ventricular pacing stimulus. Through signal processing, a number of features are parsed from the signal and a determination is made as to whether the ventricular pacing stimulus evoked a response from the ventricle.

公开(公告)号：US11938325B2

公开(公告)日：2024-03-26

申请号：US17337530

申请日：2021-06-03

Applicant: Medtronic, Inc.

Inventor： Richard M. T. Lu ,  Subham Ghosh ,  Robert W. Stadler

IPC: A61N1/36 ,  A61B5/361 ,  A61N1/362 ,  A61N1/368 ,  A61N1/37

CPC classification number: A61N1/371 ,  A61B5/361 ,  A61N1/3624 ,  A61N1/36842 ,  A61N1/3716 ,  A61N1/3622 ,  A61N1/3684 ,  A61N1/36843

Abstract: The present disclosure pertains to cardiac pacing methods and systems, and, more particularly, to cardiac resynchronization therapy (CRT). In particular, the present disclosure pertains to determining whether a patient is experiencing atrial fibrillation (AF). If the patient is experiencing AF, the efficacy of CRT is determined. A signal is sensed in response to a ventricular pacing stimulus. Through signal processing, a number of features are parsed from the signal and a determination is made as to whether the ventricular pacing stimulus evoked a response from the ventricle.

公开(公告)号：US11911168B2

公开(公告)日：2024-02-27

申请号：US17193801

申请日：2021-03-05

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/365 ,  A61B5/367 ,  A61B5/282 ,  A61B5/00 ,  A61B5/339

CPC classification number: A61B5/367 ,  A61B5/282 ,  A61B5/339 ,  A61B5/6823 ,  A61B5/7475

Abstract: Systems and methods are described herein for determining whether cardiac conduction system pacing therapy may be beneficial and/or determining how proximal or distal a cardiac conduction system block may be using external cardiac signals. To do so, one or more left-sided metrics of electrical heterogeneity information may be generated based on left-sided surrogate cardiac electrical measured using a plurality of left external electrodes.

公开(公告)号：US20240032844A1

公开(公告)日：2024-02-01

申请号：US18220911

申请日：2023-07-12

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61B5/353 ,  A61B5/00

CPC classification number: A61B5/353 ,  A61B5/6823 ,  A61B5/7203

Abstract: Systems and methods of generating atrial electrical heterogeneity using electrical activity monitored using a plurality of external electrodes are described herein. The atrial electrical heterogeneity may include P-wave electrical heterogeneity. The atrial electrical heterogeneity generated from electrical activity monitored during atrial pacing therapy may be used to evaluate and adjust atrial pacing therapy. The atrial electrical heterogeneity generated from electrical activity monitored during intrinsic activation may be used to evaluate a patient's cardiac condition.

公开(公告)号：US11850431B2

公开(公告)日：2023-12-26

申请号：US17670195

申请日：2022-02-11

Applicant: Medtronic, Inc.

Inventor： Berthold Stegemann ,  Richard Cornelussen ,  Joeri Heynens ,  Subham Ghosh

IPC: A61N1/368 ,  A61B5/363 ,  A61B5/364 ,  A61N1/39 ,  A61N1/05 ,  A61N1/362 ,  A61N1/365 ,  A61N1/37

CPC classification number: A61N1/36843 ,  A61B5/363 ,  A61B5/364 ,  A61N1/056 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3688 ,  A61N1/36514 ,  A61N1/39622 ,  A61N1/371

Abstract: An implantable device and associated method for delivering multi-site pacing therapy is disclosed. The device comprises a set of electrodes including a first and second left ventricular electrodes spatially separated from one another and a right ventricular electrode, all coupled to an implantable pulse generator. The processing circuit coupled to the implantable pulse generator, the processing circuit configured to determine whether a prospective heart failure condition has occurred and if so to trigger the pulse generator to switch from a first pacing mode to a second pacing mode, the first pacing mode comprising delivering only a first pacing pulse to a left ventricle (LV) and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle and the second pacing mode comprising delivering first and a second pacing pulses to the LV and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle.

公开(公告)号：US11813464B2

公开(公告)日：2023-11-14

申请号：US17361721

申请日：2021-06-29

Applicant: Medtronic, Inc.

Inventor： Ruth N. Klepfer ,  Manfred Justen ,  Subham Ghosh ,  Jeffrey M. Gillberg

IPC: A61B5/367 ,  A61N1/37 ,  A61N1/362 ,  A61B5/339 ,  A61B5/00 ,  A61B5/366

CPC classification number: A61N1/3702 ,  A61B5/339 ,  A61B5/366 ,  A61B5/367 ,  A61B5/4836 ,  A61N1/3625 ,  A61N1/3706 ,  A61B2560/02

Abstract: Systems, interfaces, and methods are described herein related to the evaluation of a patient's cardiac conduction system and evaluation of cardiac conduction system pacing therapy being delivered to the patient's cardiac conduction system. Evaluation of the patient's cardiac conduction system may utilize a plurality of breakthrough maps to determine where a cardiac conduction system block may be located. Evaluation of cardiac conduction system pacing therapy may utilize various electrical heterogeneity information monitored before and during delivery of cardiac conduction system pacing therapy.

公开(公告)号：US20230149719A1

公开(公告)日：2023-05-18

申请号：US17982638

申请日：2022-11-08

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Elizabeth A. Schotzko

IPC: A61N1/368 ,  A61N1/372 ,  A61N1/365 ,  A61B5/33 ,  A61B5/282

CPC classification number: A61N1/3682 ,  A61B5/33 ,  A61B5/282 ,  A61N1/36585 ,  A61N1/37247

Abstract: Systems and methods are described herein for configuration of cardiac therapy. The systems and methods may select, or determine, a plurality of different configuration parameters based electrical activity monitored or measured using a plurality of external electrodes. For example, the systems and methods may select, or determine, a left ventricular pacing vector, adaptive or non-adaptive pacing therapy, an interventricular pacing delay, and a atrioventricular pacing delay.

公开(公告)号：US11633607B2

公开(公告)日：2023-04-25

申请号：US16521000

申请日：2019-07-24

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/368 ,  A61N1/375 ,  A61N1/05

Abstract: An implantable medical system may provide atrioventricular synchronous pacing using the ventricular septal wall. The system may include a ventricular electrode coupled to an intracardiac housing or a first medical lead implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the left ventricle of the patient's heart and a right atrial electrode coupled to a leadlet or second medical lead to deliver cardiac therapy to or sense electrical activity of the right atrium of the patient's heart. A right ventricular electrode may be coupled to the intracardiac housing or the first medical lead and implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the right ventricle of the patient's heart.