公开(公告)号：US20230390581A1

公开(公告)日：2023-12-07

申请号：US17830162

申请日：2022-06-01

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION

Inventor： Sean Frigo ,  Wesley Culberson ,  John Stasko

IPC: A61N5/10

CPC classification number: A61N5/1036 ,  A61N2005/1041 ,  A61N5/1038 ,  A61N5/1045

Abstract: A system and method are provided for assessing a radiation therapy plan to be implemented on a particular radiation therapy system that includes a multi-leaf collimator (MLC). The method includes receiving a radiation therapy plan and calculating at least one metric indicating transmission characteristics of a beam delivered using the particular radiation therapy system to perform the radiation therapy plan using a model of the MLC having a plurality of zones, wherein each zone is classified based on the transmission characteristics. The method also includes evaluating the at least one metric against a tolerance for variation between the radiation therapy plan and an implementation of the radiation therapy plan on the particular radiation therapy system and generating an alert indicating that the at least one metric is outside the tolerance.

公开(公告)号：US11833370B2

公开(公告)日：2023-12-05

申请号：US17446455

申请日：2021-08-30

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Weiyuan Wang

IPC: A61N5/10

CPC classification number: A61N5/1045 ,  A61N5/1036 ,  A61N2005/1087

Abstract: A method for irradiation based on a fluence map includes determining a shield type of each row of a fluence map. The method also includes determining, for each of the two rows, a movement curve indicating a relationship between an irradiation dose in the each of the two rows and a moving position of a leaf pair corresponding to the each of the two rows. The method further includes determining an initial irradiation dose for each of the movement curves and synchronizing one of the movement curves based on the shield types of the two rows. The method also includes selecting at least one irradiation dose of at least one point on an irradiation dose axis and generating a control point according to the selected irradiation dose.

公开(公告)号：US20230356003A1

公开(公告)日：2023-11-09

申请号：US18181147

申请日：2023-03-09

Applicant: RefleXion Medical, Inc.

Inventor： Yevgen VORONENKO ,  Peter Demetri Olcott ,  Debashish Pal ,  Rostem Bassalow

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61N5/1081 ,  A61N5/1049 ,  A61N5/1071 ,  A61N5/1036 ,  A61N5/1039 ,  A61N2005/1091 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1061 ,  A61N5/1068

Abstract: Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.

公开(公告)号：US20230310891A1

公开(公告)日：2023-10-05

申请号：US17706902

申请日：2022-03-29

Applicant: Siemens Healthineers International AG

Inventor： Jarkko Y. Peltola ,  Mikko Laitinen ,  Heini Hyvönen

IPC: A61N5/10

CPC classification number: A61N5/1036 ,  A61N5/1045 ,  A61N5/1075 ,  A61N2005/1074

Abstract: A control circuit generates an optimized radiation treatment plan with respect to an adjustable collimation device and then automatically generates at least one quality assurance accuracy value corresponding to the optimized radiation treatment plan. By one approach, the aforementioned plan comprises a plurality of treatment fields. In such a case, automatically generating at least one quality assurance accuracy value can comprise, at least in part, automatically generating at least one quality assurance accuracy value for each of at least a substantial number (or all) of those treatment fields. By one approach, the aforementioned quality assurance accuracy value comprises a dimensionless metric. This dimensionless metric may represent, for example, dosimetric accuracy corresponding to the optimized radiation treatment plan.

公开(公告)号：US11712586B2

公开(公告)日：2023-08-01

申请号：US17499702

申请日：2021-10-12

Applicant: Accuray Incorporated

Inventor： Andrea Cox ,  Eric Schnarr

IPC: A61N5/10

CPC classification number: A61N5/1075 ,  A61N5/1036 ,  A61N5/1039 ,  A61N5/1045 ,  A61N5/1069 ,  A61N5/1081 ,  A61N5/1083 ,  A61N2005/1055 ,  A61N2005/1059 ,  A61N2005/1061

Abstract: A method includes detecting a potential setup error in a radiation treatment delivery session of a radiation treatment delivery system, wherein the setup error corresponds to a change in a current position of a treatment target relative to a prior position of the treatment target, and wherein the change includes a rotation relative to the prior position of the treatment target. The method further includes modifying, by a processing device, one or more planned leaf positions of a multileaf collimator (MLC) of a linear accelerator (LINAC) of the radiation treatment delivery system to compensate for the potential setup error corresponding to the rotation of the prior position of the treatment target.

公开(公告)号：US11691030B2

公开(公告)日：2023-07-04

申请号：US16606039

申请日：2018-04-18

Applicant: The Regents of the University of California

Inventor： Ke Sheng

IPC: A61N5/10 ,  G16H30/20

CPC classification number: A61N5/1047 ,  A61N5/1037 ,  A61N5/1039 ,  A61N5/1067 ,  G16H30/20 ,  A61N5/1036

Abstract: Systems and method for generating and executing volumetric modulated arc therapy (“VMAT”) plans are provided. In some aspects, the method includes receiving a representation of a subject comprising information related to target and non-target volumes of interest, and generating an objective function based on the representation of the subject, wherein the objective function accounts for dynamic collimator rotation. The method also includes performing an iterative optimization process, using the objective function, to generate a dynamic collimator VMAT plan, and generating a report in accordance with the dynamic collimator VMAT plan.

公开(公告)号：US11648418B2

公开(公告)日：2023-05-16

申请号：US16016272

申请日：2018-06-22

Applicant: RefleXion Medical, Inc.

Inventor： Michael Kirk Owens ,  Rostem Bassalow ,  Peter Demetri Olcott ,  Yevgen Voronenko ,  David Quentin Larkin ,  Samuel Mazin

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1039 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1067 ,  A61N5/1068 ,  A61N5/1036 ,  A61N5/1037 ,  A61N5/1038 ,  A61N5/1045 ,  A61N2005/1034 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1058

Abstract: Disclosed herein are systems and methods for adapting and/or updating radiotherapy treatment plans based on biological and/or physiological data and/or anatomical data extracted or calculated from imaging data acquired in real-time (e.g., during a treatment session). Functional imaging data acquired at the time of radiation treatment is used to modify a treatment plan and/or dose delivery instructions to provide a prescribed dose distribution to patient target regions. Also disclosed herein are methods for evaluating treatment plans based on imaging data acquired in real-time.

公开(公告)号：US20190209864A1

公开(公告)日：2019-07-11

申请号：US16220239

申请日：2018-12-14

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Johannes STAHL ,  Jonathan MALTZ

IPC: A61N5/10

CPC classification number: A61N5/1045 ,  A61N5/1031 ,  A61N5/1036 ,  A61N5/1039 ,  A61N5/1049 ,  A61N5/1077 ,  A61N2005/1035 ,  A61N2005/1041

Abstract: A method for delivering radiation treatment may include defining a preliminary trajectory including a plurality of control points. Each control point may be associated with position parameters of a gantry and a couch. The method may also include generating a treatment plan based on the preliminary trajectory by optimizing an intensity and position parameters of a collimator and MLC leaves for each control point. The method may also include decomposing the treatment plan into a delivery trajectory including the plurality of control points. Each of the plurality of control points may be further associated with the optimized intensity, the optimized position parameters of the collimator and the MLC leaves, an output rate, and a motion parameter of each of the gantry, the couch, the collimator, and the MLC leaves. The method may further include instructing a radiation delivery device to deliver the treatment plan according to the delivery trajectory.

公开(公告)号：US20180117358A1

公开(公告)日：2018-05-03

申请号：US15336402

申请日：2016-10-27

Applicant: Varian Medical Systems International AG

Inventor： Janne I. NORD ,  Juha KAUPPINEN ,  Lasse H. TOIMELA

IPC: A61N5/10

CPC classification number: A61N5/1037 ,  A61N5/103 ,  A61N5/1031 ,  A61N5/1036 ,  A61N5/1045 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1068 ,  A61N5/1081

Abstract: An apparatus for use in a treatment planning process or in a treatment process, includes: an input for obtaining a parameter representing a number of beam on-off transitions; and a treatment planner configured to optimize a treatment plan based on parameter representing the number of beam on-off transitions. An apparatus includes: an input configured to obtain a width of a gating window for a treatment plan; and a gating window adjustor configured to adjust the width of the gating window during a treatment session. An apparatus includes: a dose calculator configured to calculate doses for different treatment variations; an evaluator configured to evaluate treatment acceptance criteria against the calculated doses; and a delivery limit module configured to determine one or more limits for one or more delivery parameters based on an evaluation of the treatment acceptance criteria by the evaluator.

公开(公告)号：US20170354393A1

公开(公告)日：2017-12-14

申请号：US15182080

申请日：2016-06-14

Applicant: Supratik BOSE ,  Johannes N. STAHL ,  Jonathan S. MALTZ

Inventor： Supratik BOSE ,  Johannes N. STAHL ,  Jonathan S. MALTZ

IPC: A61B6/00 ,  A61N5/10

CPC classification number: A61B6/547 ,  A61N5/1036 ,  A61N5/1047 ,  A61N2005/1074

Abstract: A system, medium, and method including obtaining a plurality of positions for multiple components defined by a plan; obtaining a set of constraints that express limitations for the multiple components at the plurality of positions, the constraints being applicable to a plan where the multiple components synchronously change their positions with time to traverse a prescribed sequence of the plurality of positions, at least one of the multiple components being further constrained to change its position over time by staying within a predefined tolerance to a predefined smooth function of position over time between different positions; determining a trajectory of position and a minimum duration in which the multiple components completely synchronously traverse the prescribed sequence of positions while satisfying the constraints for the multiple components; and generating a record of the determined trajectory of position and the minimum duration for the plurality of components.