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161.
公开(公告)号:US20240033528A1
公开(公告)日:2024-02-01
申请号:US18350010
申请日:2023-07-11
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor: Daran DeShazo , Christopher Palmer
IPC: A61N1/36
CPC classification number: A61N1/36167 , A61N1/36157 , A61N1/36153
Abstract: System and methods for providing a pulsed therapy comprises an implantable pulse generator (IPG) having circuitry configured to control generation and delivery of electrical pulses using at least one electrode of a stimulation lead. The IPG further comprises memory configured to store program instructions and one or more processors configured to execute the program instructions. The one or more processors are configured to deliver the pulses, having a corresponding pulse duration and an amplitude, to the at least one electrode. The amplitude can vary over the pulse duration of at least one of the pulses. The processor(s), monitor a signal indicative of a present level of the amplitude of the at least one pulse, and based on the signal, declare a pulse valid based on the present level satisfying an initial criteria for at a sub-duration of the pulse duration that is less than an entire pulse duration.
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公开(公告)号:US20240033523A1
公开(公告)日:2024-02-01
申请号:US18342378
申请日:2023-06-27
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor: Daran DeShazo
IPC: A61N1/36
CPC classification number: A61N1/36139 , A61N1/36125
Abstract: Provided is an implantable pulse generator (IPG) for providing electrical pulses to a patient during neurostimulation therapy. The IPG includes a controller for controlling operations of the IPG, a battery for powering the IPG, a therapeutic stimulation circuitry for generating electrical pulses to stimulate neural tissue of the patient, and internal diagnostic circuitry for digitizing device signals to control operations of the IPG. The internal diagnostic circuitry includes a multi-stage comparator including a pre-amplifier configured to receive an analog input signal and convert the analog input signal into a first analog output signal and second analog output signal. The multi-stage comparator also including a first latch circuit with a first receiving device that receives the first analog output signal, a second receiving device that receives the second analog output signal, and configured to convert the first analog output signal and second analog output signal into a digital output signal.
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公开(公告)号:US11883648B2
公开(公告)日:2024-01-30
申请号:US17317429
申请日:2021-05-11
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor: Dirk De Ridder
CPC classification number: A61N1/0529 , A61N1/0531 , A61N1/0553 , A61N1/361 , A61N1/3605 , A61N1/3611 , A61N1/36017 , A61N1/36021 , A61N1/36062 , A61N1/36071 , A61N1/36085 , A61N1/36096 , A61N1/36117 , A61M5/14276 , A61N1/36036 , A61N2/006
Abstract: The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds.
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公开(公告)号:US20230414288A1
公开(公告)日:2023-12-28
申请号:US18242888
申请日:2023-09-06
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor: Yagna Pathak , Simeng Zhang , Dehan Zhu , Anahita Kyani , Hyun-Joo Park , Erika Ross
IPC: A61B34/10 , G06T7/70 , G16H30/40 , G06V10/25 , A61B5/055 , A61B6/03 , A61B6/00 , G06N3/08 , G06T7/00 , G06F18/214
CPC classification number: A61B34/10 , G06T7/70 , G16H30/40 , G06V10/25 , A61B5/055 , A61B6/032 , A61B6/469 , A61B6/501 , A61B6/5223 , A61B6/5247 , G06N3/08 , G06T7/0014 , G06F18/214 , A61B2034/107 , G06V2201/031 , A61B2505/05 , A61N1/0534
Abstract: A system and method for facilitating DBS electrode trajectory planning using a machine learning (ML)-based feature identification scheme configured to identify and distinguish between various regions of interest (ROIs) and regions of avoidance (ROAs) in a patient's brain scan image. In one arrangement, standard orientation image slices as well as re-sliced images in non-standard orientations are provided in a labeled input dataset for training a CNN/ANN for distinguishing between ROIs and ROAs. Upon identification of the ROIs and ROAs in the patient's brain scan image, an optimal trajectory for implanting a DBS lead may be determined relative to a particular ROI while avoiding any ROAs.
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公开(公告)号:US20230372717A1
公开(公告)日:2023-11-23
申请号:US18230787
申请日:2023-08-07
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor: Filippo Agnesi
CPC classification number: A61N1/37247 , A61N1/36067 , A61N1/0551 , A61N1/0534 , A61N1/36167 , A61N1/36185 , A61N1/36175 , A61N1/36135 , A61N1/36132 , A61N1/36125 , A61N1/36062 , A61N1/0512 , A61N1/0509 , A61N1/0514 , A61N1/36171 , A61N1/36178 , A61N1/0553 , A61N1/362
Abstract: The systems and methods described herein generally relate to adjusting a neurostimulation (NS) therapy based on drug pharmacokinetics of a patient. The systems and methods deliver an NS therapy to a portion of electrodes of a lead positioned proximate to neural tissue of interest, which is associated with a target region. The NS therapy is defined by stimulation parameters. The systems and methods determine a trigger event indicative of a drug being administered to a patient. The drug is configured to affect at least one of the neural tissue of interest or the target region. The systems and methods adjust one or more of the stimulation parameters based on the PS profile.
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166.
公开(公告)号:US20230317303A1
公开(公告)日:2023-10-05
申请号:US18331342
申请日:2023-06-08
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor: Scott DeBates , Douglas Alfred Lautner , Tucker Tomlinson , James Nagle
IPC: G16H80/00 , G16H20/30 , G16H40/67 , G16H10/60 , A61N1/372 , H04L43/04 , H04L65/1069 , H04L65/80 , H04N7/14 , A61B5/00
CPC classification number: G16H80/00 , G16H20/30 , G16H40/67 , G16H10/60 , A61N1/37247 , A61N1/37282 , H04L43/04 , H04L65/1069 , H04L65/80 , H04N7/14 , A61B5/0031 , A61B5/7435
Abstract: A system and method for facilitating remote care management involving a patient having an implantable medical device (IMD). Upon establishing a remote care session between a patient controller device and a clinician programmer, wherein the clinician and the patient are remotely located with respect to each other, input from the patient or the clinician may be received via a user interface control associated with a particular functionality or aspect of the remote care session, including audiovisual (AV) communications, remote therapy programming, and related context. Responsive to the user input, a dialog interface is effectuated at one of the patient controller device and/or the clinician programmer. A user characterization label is received via the dialog interface from the user, wherein the user characterization label is indicative of a subjective assessment of the particular functionality of the remote care session, which may be used in generating user-labeled data pertaining thereto.
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167.
公开(公告)号:US20230241399A1
公开(公告)日:2023-08-03
申请号:US18131465
申请日:2023-04-06
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor: Christopher S. L. Crawford
CPC classification number: A61N1/36139 , A61N1/37235 , A61N1/36067 , A61N1/36021 , A61N1/36071 , A61N1/36167 , A61B5/1113
Abstract: This application is generally related to systems and methods for providing a medical therapy to a patient by tracking patient activity and adjusting medical therapy based on occurrence of different types of activities performed by the patient while automatically rescheduling stimulation programs based on detected patient activity.
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168.
公开(公告)号:US20230181908A1
公开(公告)日:2023-06-15
申请号:US18109235
申请日:2023-02-13
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor: Christopher S. L. Crawford
CPC classification number: A61N1/36135 , A61N1/36196 , A61N1/37247 , A61N1/37282 , A61N1/36003 , A61N1/36192
Abstract: This application is generally related to systems and methods for providing a medical therapy to a patient by tracking patient activity and adjusting medical therapy based on occurrence of different types of activities performed by the patient including user indicated activities inputted from an icon driven user interface of an external patient controller device.
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169.
公开(公告)号:US20230117166A1
公开(公告)日:2023-04-20
申请号:US17968739
申请日:2022-10-18
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor: Kyuwan Choi , Erika Ross , Diane Whitmer
Abstract: The present disclosure provides systems and methods for providing neurostimulation therapy using multi-dimensional patient features. The multi-dimensional patient features may include features in respective frequency bands for selected cortical sites from EEG localization data. Additionally or alternatively, the multi-dimensional patient features may include features from patient physiological data or other patient activity data. The multi-dimensional feature data may be compared against AI/ML models of patient and/or healthy population members. Closed-loop therapy adjustments may be applied to a respective patient's neurostimulation therapy using the multi-dimensional patient feature analysis.
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170.
公开(公告)号:US20230066914A1
公开(公告)日:2023-03-02
申请号:US17405804
申请日:2021-08-18
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor: Gavin Rade , Daran DeShazo
Abstract: An implantable medical device (IMD) configured to provide stimulation therapy using an instruction set architecture (ISA) includes a main processor operating at a first frequency and a secondary processor operating at a second frequency lower than the first frequency. Example ISA may comprise assembly-language-like instructions that may be executed by the secondary processor for configuring one or more stimulation engines (SEs) to cause stimulation of select electrode sets of a lead system based on one or more pulse definitions and one or more timing definitions corresponding to a therapy program selection effectuated by a user at an external device.
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