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公开(公告)号:US10396734B1
公开(公告)日:2019-08-27
申请号:US16425274
申请日:2019-05-29
Inventor: Sung Min Park
Abstract: Disclosed is a differential transimpedance amplifier. The differential transimpedance amplifier includes a common gate amplifier configured to receive an electrical signal from an input node, and a common source amplifier configured to have a feedback resistor and receive the electrical signal form the input node. An output signal of the common gate amplifier and an output signal of the common source amplifier form a differential signal pair. The common gate amplifier and the common source amplifier each includes a load having a transformer which removes an effect of parasitic capacitance.
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162.
公开(公告)号:US20190194611A1
公开(公告)日:2019-06-27
申请号:US15561500
申请日:2016-03-23
Applicant: EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION , KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Inventor: Inho JO , Yoon Shin PARK , Sang Hoon LEE , Ji-Young HWANG , Yels JUN , Yoon Mi JIN , Gyuong Ah KIM , Ha Yeong KIM , Han Su KIM , Sung Chul JUNG
IPC: C12N5/071 , C12N5/0775 , C07K14/635
CPC classification number: C12N5/0617 , C07K14/635 , C12N5/0668 , C12N2501/16 , C12N2501/41 , C12N2506/1392 , C12N2513/00 , C12N2533/30
Abstract: The present invention relates to: a method for producing a spheroid form of tonsil-derived stem cells, the method enhancing growth and differentiation efficiency of tonsil-derived stem cells; and a method for producing a spheroid form of parathyroid hormones from the same. The method of the present invention for producing a spheroid form of tonsil-derived stem cells cultures the tonsil-derived stem cells in the form of a spheroid to thereby enhance the proliferation rate of the stem cells per se and remarkably increase differentiation potency into parathyroid cells. Thereby, the method has a remarkable effect on the growth and differentiation of the tonsil-derived stem cells into parathyroid cells, etc.
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公开(公告)号:US20190125239A1
公开(公告)日:2019-05-02
申请号:US15882254
申请日:2018-01-29
Inventor: In Kyoon LYOO , Han Byul CHO , Ga Hae HONG
Abstract: Provided is a method and apparatus for predicting a posttraumatic behavior problem that may predict a posttraumatic violent behavior problem of an individual, in detail, that may determine a biological phenotype of an individual experiencing a traumatic event within a predetermined period after the individual is exposed to the traumatic event, predict a violent symptom presentation probability of the individual based on the biological phenotype of the individual, and suggest an objective basis for preventive intervention in a development of posttraumatic stress disorder (PTSD) of the individual based on a prediction result.
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164.
公开(公告)号:US20190016887A1
公开(公告)日:2019-01-17
申请号:US16032712
申请日:2018-07-11
Inventor: Myung Hwa Kim , Won-Suk Kim , Hye Su Jang , Yejung Lee , Ye-Seul Yun , Yong-Ju Kwon
Abstract: The present disclosure relates to novel fluoromonomer and fluorooligomer compounds, a photopolymerizable composition including these compounds, methods for producing these compounds, and a hydrophobic film using the photopolymerizable composition.
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165.
公开(公告)号:US20180332147A1
公开(公告)日:2018-11-15
申请号:US15957689
申请日:2018-04-19
Inventor: Hyunggon Park , Jungmin Kwon
IPC: H04L29/08
CPC classification number: H04L69/324
Abstract: Provided are a network encoding method and apparatus, and a network decoding method and apparatus that performs network encoding and decoding through a transposed matrix of a unitary matrix decomposed from an encoding coefficient matrix by an eigen-decomposition. The network encoding method may include generating a random symmetric matrix indicating a binary square matrix, extracting an encoding coefficient matrix by decomposing the generated random symmetric matrix, generating encoding data by encoding source data using the extracted encoding coefficient matrix, forming a data packet including the generated encoding data and the encoding coefficient matrix, and converting the formed data packet from a real number field to a Galois field.
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公开(公告)号:US20180305377A1
公开(公告)日:2018-10-25
申请号:US16024454
申请日:2018-06-29
Inventor: Sang Won KANG , Dong Hoon KANG , Doo Jae LEE
IPC: C07D513/08 , A61K31/548 , A61K31/00 , C12Q1/26
CPC classification number: C07D513/08 , A61K31/00 , A61K31/548 , C12Q1/26 , G01N2333/90212 , G01N2500/02
Abstract: The present invention relates to an epidithiodioxopiperazine derivative represented by the following Chemical Formula 1 or its reduced derivative; a method for preparing a compound represented by Chemical Formula 1 having improved intracellular permeability and mimicking the activity of 2-Cys-Prx in its reduced form in the cells; a pharmaceutical composition for preventing or treating vascular diseases comprising an epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient; a drug delivery device for local administration including the pharmaceutical composition; and a pharmaceutical composition for inhibiting melanoma metastasis comprising the epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient.
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167.
公开(公告)号:US10091674B2
公开(公告)日:2018-10-02
申请号:US14655369
申请日:2014-12-15
Inventor: Jeong-Ho Kim
Abstract: A location determining method 200 for sensor apparatus placements in building includes: a step in which a first measuring device transmits a digitally modulated first test packet through a specific channel at a first location in a building (210); a step in which a second measuring device receives the first test packet and transmits a first echo back signal through the specific channel at a second location in the building (220); a step in which the first measuring device receives the first echo back signal transmitted from the second measuring device and measures a first channel quality of the specific channel based on the first echo back signal (230); a step in which the first measuring device transmits a digitally modulated second test packet through the specific channel (240); a step in which the second measuring device receives the second test packet and transmits a second echo back signal through the specific channel (250); and a step in which the first measuring device receives the second echo back signal transmitted from the second measuring device and measures a second channel quality of the specific channel based on the second echo back signal (260).
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公开(公告)号:US20180214565A1
公开(公告)日:2018-08-02
申请号:US15877284
申请日:2018-01-22
Inventor: Kyunglim LEE
IPC: A61K47/64 , C07K7/08 , C07K14/46 , C07K14/47 , C07K7/06 , C07K14/435 , A61K47/65 , A61K48/00 , C07K16/18
CPC classification number: A61K47/64 , A61K47/65 , A61K48/0008 , C07K7/06 , C07K7/08 , C07K14/435 , C07K14/46 , C07K14/47 , C07K16/18
Abstract: Provided are transmembrane complexes that contain a protein transduction domain (PTD) from the N-terminus of IgE-dependent histamine-releasing factor (HRF) and a target substance that is to be delivered into a cell. Also provided are nucleic acid molecules encoding the transmembrane complex, and methods of delivering the target substance into a cell interior by contacting the transmembrane complex with a cell. Also provided are transfection kits containing the PTD and the target substance.
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公开(公告)号:US09765090B2
公开(公告)日:2017-09-19
申请号:US14286929
申请日:2014-05-23
Inventor: Sang Won Kang , Dong Hoon Kang , Doo Jae Lee
IPC: A61K31/54 , C07D513/08 , C12Q1/26 , A61K31/00
CPC classification number: A61K31/548 , A61K31/00 , C07D513/08 , C12Q1/26 , G01N2333/90212 , G01N2500/02
Abstract: The present invention relates to an epidithiodioxopiperazine derivative represented by the following Chemical Formula 1 or its reduced derivative; a method for preparing a compound represented by Chemical Formula 1 having improved intracellular permeability and mimicking the activity of 2-Cys-Prx in its reduced form in the cells; a pharmaceutical composition for preventing or treating vascular diseases comprising an epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient; a drug delivery device for local administration including the pharmaceutical composition; and a pharmaceutical composition for inhibiting melanoma metastasis comprising the epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient.
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公开(公告)号:US20170240557A1
公开(公告)日:2017-08-24
申请号:US15440748
申请日:2017-02-23
Inventor: Juyoung Yoon , Xin Zhou , Ying Hu , Liyan Chen
IPC: C07D491/107 , C07D221/14 , G01N21/78 , C07D271/12 , G01N21/64 , C07D311/88 , C07D209/14
CPC classification number: C07D491/107 , C07D209/14 , C07D221/14 , C07D271/12 , C07D311/88 , G01N2021/7783 , G01N2021/7786
Abstract: The present invention relates to a compound for detecting phosgene and DCP (diethyl chlorophosphate) and a composition for detecting phosgene and DCP (diethyl chlorophosphate) comprising the said compound. More precisely, the compound for detecting phosgene and DCP of the present invention can selectively detect phosgene and DCP either in the liquid phase of gas phase by detecting the changes of fluorescence and color development very quickly within a few seconds with nM sensitivity. Therefore, the compound can also be effectively used as an ingredient for the composition and kit for the detection of one or more materials selected from the group consisting of phosgene and DCP.
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