公开(公告)号：US20070032429A1

公开(公告)日：2007-02-08

申请号：US11544507

申请日：2006-10-05

Applicant: David Wright ,  D. Parks

Inventor： David Wright ,  D. Parks

IPC: A61K38/54 ,  A61K38/10

CPC classification number: A61K38/10 ,  A61K38/204 ,  C07K5/0212 ,  C07K7/02

Abstract: This invention provides methods of treatment using retro-inverso peptides derived from interleukin-6 (IL-6) having between 15 and about 40 amino acids, and including the sequence that is retro-inverso with respect to SEQ ID NO: 1, i.e. wherein said peptide comprises the sequence D-Glu-D-Ala-D-Met-D-Lys-D-Pro-D-Leu-D-Asn-D-Leu-D-Asn-D-Asn-D-Glu-D-Ala-D-Leu-D-Ala-D-Glu. The peptides of the invention have the same activity as native IL-6 and also have neurotrophic activity. The peptides of the invention are also less susceptible to proteolytic degradation in vivo because of their D-amino acid linkage.

Abstract translation: 本发明提供了使用衍生自具有15至约40个氨基酸的白细胞介素-6（IL-6）的逆转换肽的治疗方法，并且包括相对于SEQ ID NO：1反向逆转的序列，即其中 所述肽包含序列D-Glu-D-Ala-D-Met-D-Lys-D-Pro-D-Leu-D-Asn-D-Leu-D-Asn-D-Asn-D-Glu-D -Ala-D-Leu-D-Ala-D-Glu。 本发明的肽具有与天然IL-6相同的活性并具有神经营养活性。 由于它们的D-氨基酸连接，本发明的肽也不太容易在体内蛋白水解降解。

公开(公告)号：US20070011040A1

公开(公告)日：2007-01-11

申请号：US11405067

申请日：2006-04-17

Applicant: David Wright ,  Arun Ramaswamy ,  Dan Nelson ,  Glen Vilches

Inventor： David Wright ,  Arun Ramaswamy ,  Dan Nelson ,  Glen Vilches

IPC: G06F17/30

CPC classification number: H04N21/2407 ,  G06Q30/02 ,  H04H60/31 ,  H04H60/32 ,  H04H60/33 ,  H04H60/37 ,  H04H60/45 ,  H04H60/52 ,  H04H60/58 ,  H04N21/25883 ,  H04N21/41407 ,  H04N21/4394 ,  H04N21/44204 ,  H04N21/44222 ,  Y10S707/99935

Abstract: As disclosed herein, media metering functionality may be imparted to a panelists device that was not previously capable of media metering. According to one example, a method of providing a communication device with media metering functionality includes asking a potential panelist to participate in a survey, receiving an affirmative response from the potential panelist, and providing metering functionality to a portable device of the potential panelist.

Abstract translation: 如本文所公开的，媒体计量功能可以被赋予以前不能进行媒体测量的小组成员设备。 根据一个示例，提供具有媒体计量功能的通信设备的方法包括要求潜在的小组成员参与调查，从潜在小组成员接收肯定的响应，以及向潜在小组成员的便携式设备提供计量功能。

公开(公告)号：US20060254680A1

公开(公告)日：2006-11-16

申请号：US11486733

申请日：2006-07-14

Applicant: Theodor Rottwinkel ,  David Wright ,  Richard Hamerton ,  Jeremy Brown ,  John Ward

Inventor： Theodor Rottwinkel ,  David Wright ,  Richard Hamerton ,  Jeremy Brown ,  John Ward

IPC: C22F1/04

CPC classification number: B41N1/083 ,  C22C21/00 ,  C22C21/06 ,  C22F1/04 ,  C22F1/047

Abstract: The invention discloses an Al alloy suitable for processing into a lithographic sheet, the alloy having a composition in wt %: Mg 0.05 to 0.30, Mn 0.05 to 0.25, Fe 0.11 to 0.40, Si up to 0.25, Ti up to 0.03, B up to 0.01, Cu up to 0.01, Cr up to 0.03, Zn up to 0.15, unavoidable impurities up to 0.05 each, 0.15 total, Al balance. Also disclosed is a method of processing the Al alloy.

Abstract translation: 本发明公开了一种适用于加工成平版印刷片的Al合金，该合金的重量％为：Mg 0.05〜0.30，Mn 0.05〜0.25，Fe 0.11〜0.40，Si：0.25以下，Ti：0.03以下，B： 至0.01，Cu高达0.01，Cr高达0.03，Zn高达0.15，不可避免的杂质高达0.05，总共为0.15，Al平衡。 还公开了一种处理Al合金的方法。

公开(公告)号：US20060103041A1

公开(公告)日：2006-05-18

申请号：US10992225

申请日：2004-11-18

Applicant: Kai Su ,  Richard Lu ,  David Wright ,  Debbie Makita

Inventor： Kai Su ,  Richard Lu ,  David Wright ,  Debbie Makita

IPC: B29D11/00

CPC classification number: B29D11/00528 ,  B29C33/40 ,  B29D11/00413 ,  B29D11/00538 ,  Y10S424/808 ,  Y10S425/808

Abstract: The present invention encompasses, in part, a method and apparatus for lens casting in which two molds, preferably formed of plastic, are interconnected or joined together via a ring to form a mold cavity having substantially the same dimensions of the lens to be formed therein. The invention is further directed to compositions and methods used in lens casting. In a first implementation the invention includes a mold having a ring having an interior periphery; a front mold formed of a plastic and having a lens-forming surface, an edge circumscribing the lens-forming surface that is sized to be complementarily received within a portion of the interior periphery of the ring, and a base having dimensions greater than the interior periphery; and a rear mold formed of a plastic and having a lens-forming surface.

Abstract translation: 本发明部分地包括一种用于透镜铸造的方法和装置，其中优选由塑料形成的两个模具通过环相互连接或连接在一起以形成具有与其中形成的透镜基本相同的尺寸的模腔 。 本发明还涉及用于镜片铸造中的组合物和方法。 在第一实施方式中，本发明包括一具有内周的环的模具; 由塑料形成并具有透镜形成表面的前模具，围绕透镜形成表面的边缘，其尺寸设计成互补地容纳在环的内周的一部分内，以及具有大于内部尺寸的尺寸的基座 周边; 以及由塑料形成并具有透镜形成表面的后模具。

公开(公告)号：US20060069401A1

公开(公告)日：2006-03-30

申请号：US11237132

申请日：2005-09-27

Applicant: David Wright

Inventor： David Wright

IPC: A61B17/08

CPC classification number: A61B17/128 ,  A61B17/072 ,  A61B17/11 ,  A61B17/115 ,  A61B17/122 ,  A61B2017/00243 ,  A61B2017/1107 ,  A61B2017/1139

Abstract: A device for connecting two tubular vessels together in a side-by-side or tangential manner is disclosed. The device has an annulus and at least one series of fingers connected to and extending away from the annulus. In the preferred embodiment there are two sets of fingers connected to and extending away from the annulus in opposite directions. Each finger is preferably biased into an arcuate shape. In use, a deployment apparatus is used to constrain the fingers of the device to be in a relatively planar configuration. The deployment apparatus containing the device is placed between and in contact with the two tubular vessels so that one tubular vessel is above the device and one tubular vessel is below the device and so that the fingers of the device come into contact with the tissue of the vessels. As the fingers penetrate the vessels the constraint on the fingers is removed so that the fingers can assume their biased arcuate shape. In this way, the fingers penetrate and grasp the tissue of the vessels so that the device grasps the vessels and pulls the vessels toward each other.

Abstract translation: 公开了一种用于将两个管状容器并排或切向连接在一起的装置。 该装置具有环形结构，并且至少一系列手指连接到环形部分并远离环形部分。 在优选实施例中，有两组手指在相反方向上连接到环形空间并远离环形空间。 每个手指优选地被偏压成弓形。 在使用中，使用展开装置来将装置的手指限制在相对平面的构型中。 将包含该装置的展开装置放置在两个管状容器之间并与两个管状容器接触，使得一个管状容器位于装置的上方，一个管状容器位于装置下方，并且使得装置的指状物与该装置的组织接触 船只。 当手指穿透血管时，手指上的约束被去除，使得手指可以呈现它们偏置的弓形形状。 以这种方式，手指穿透和抓住血管的组织，使得装置抓住血管并将血管拉向彼此。

公开(公告)号：US20060062736A1

公开(公告)日：2006-03-23

申请号：US10522525

申请日：2004-11-17

Applicant: David Wright ,  Anthony Harman ,  Nikki Robinson ,  Garry Hodges ,  Adil Kadar

Inventor： David Wright ,  Anthony Harman ,  Nikki Robinson ,  Garry Hodges ,  Adil Kadar

IPC: A61L9/04

Abstract: A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.

Abstract translation: 用于治疗静脉曲张的治疗性泡沫包括用诸如二氧化碳，氧气或其混合物的生理气体发泡的硬化溶液。 泡沫的氮含量小于0.8％。 它可以使用包含微米尺寸的精细网格的加压罐系统来产生，气体和硬化液通过该微孔尺寸通过以制造泡沫。 或者，泡沫可以通过气体和溶液在两个注射器之间通过细网而产生。 描述了用于最小化基于罐或注射器的产品中氮的量的技术。 还公开了一种使用基于注射器的装置同时产生和递送泡沫的技术。

公开(公告)号：US20060062282A1

公开(公告)日：2006-03-23

申请号：US11206373

申请日：2005-08-17

Applicant: David Wright

Inventor： David Wright

IPC: H04B1/707

CPC classification number: H04J13/0022 ,  H04J13/16

Abstract: An improved method of framing data packets in a direct sequence spread spectrum (DSSS) system that uses one pseudo-noise code (PN-Code) to frame the packet with a start-of-packet (SOP) and end-of-packet (EOP) indicator, and a different PN-Code to encode the data payload. Furthermore, the SOP is represented by the framing PN-Code, and the EOP is represented by the inverse of the framing PN-Code. This method creates a robust framing system that enables a DSSS system to operate with a low threshold of detection, thus maximizing transmission range even in noisy environments. Additionally, the PN-Code used for the SOP and EOP indicators can be used to indicate an acknowledgement response.

Abstract translation: 在直接序列扩频（DSSS）系统中对数据分组进行成帧的改进方法，其使用一个伪噪声码（PN-Code）来以包起始分组（SOP）和分组结束（ EOP）指示符和不同的PN码对数据有效载荷进行编码。 此外，SOP由成帧PN码表示，并且EOP由成帧PN码的倒数表示。 该方法创建了一个稳健的成帧系统，使DSSS系统能够以较低的检测阈值进行操作，从而即使在嘈杂的环境下也能最大化传输范围。 另外，用于SOP和EOP指示符的PN码可用于指示确认响应。

公开(公告)号：US20050245910A1

公开(公告)日：2005-11-03

申请号：US10835038

申请日：2004-04-29

Applicant: David Wright ,  Lee Travis

Inventor： David Wright ,  Lee Travis

IPC: A61B17/00 ,  A61B19/00 ,  A61F9/007

CPC classification number: A61F9/00745 ,  A61B17/00 ,  A61B34/76 ,  A61B2017/00119 ,  A61B2017/00128

Abstract: Tactile feedback fingertip device 10 is attached to a surgical handpiece 14 and connected to a control console 24 for providing tactile feedback to a user of a surgical function or parameter.

Abstract translation: 触觉反馈指尖装置10附接到外科手持件14并连接到控制台24，以向外科功能或参数的使用者提供触觉反馈。

公开(公告)号：US20050237063A1

公开(公告)日：2005-10-27

申请号：US11138776

申请日：2005-05-26

Applicant: David Wright ,  Antoni Ziolkowski ,  Bruce Hobbs

Inventor： David Wright ,  Antoni Ziolkowski ,  Bruce Hobbs

IPC: G01V3/02 ,  G01V3/08 ,  G01V3/10 ,  G01V3/12

CPC classification number: G01V3/02

Abstract: The invention relates to a method of mapping subsurface resistivity contrasts by making multichannel transient electromagnetic (MTEM) measurements on or near the earth's surface using at least one source, receiving means for measuring the system response and at least one receiver for measuring the resultant earth response. All signals from the or each source-receiver pair are processed to recover the corresponding electromagnetic impulse response of the earth and such impulse responses, or any transformation of such impulse responses, are displayed to create a subsurface representation of resistivity contrasts. The invention enables subsurface fluid deposits to be located and identified and the movement of such fluids to be monitored.

公开(公告)号：US20050233466A1

公开(公告)日：2005-10-20

申请号：US10892000

申请日：2004-07-15

Applicant: David Wright ,  Timothy Kriewall ,  Daniel Cheek

Inventor： David Wright ,  Timothy Kriewall ,  Daniel Cheek

IPC: G01N11/14 ,  G01N11/16 ,  G01N33/49 ,  G01N33/86

CPC classification number: G01N33/4905 ,  G01N11/14 ,  G01N11/16 ,  Y10T436/111666

Abstract: A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a blood test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower major sides and a minor sidewall encloses a test chamber having a test chamber pivot element and is provided with a cartridge port for introducing a test sample into the test chamber,. Ferromagnetic agitator vane leaflets extend from an agitator pivot element supported by the test chamber pivot element intermediate the upper and lower major sides for rotational motion. The agitator vane leaflets can be swept, in response to an external magnetic field, through the test sample in the absence of coagulation. A timer is started when the agitator movement is commenced whereupon the agitator moves freely. Resistance to agitator movement due to coagulation is detected, and the coagulation time is measured.

Abstract translation: 公开了一种用于确定沉积在测试盒中的血液测试样品的凝固时间（例如TT，PT，aPTT和ACT）的系统和方法。 具有上下侧和下侧壁的盒壳体包围具有测试室枢转元件的测试室，并且设置有用于将测试样品引入到测试室中的盒端口。 铁磁搅拌器叶片叶片从由测试室枢转元件支撑的搅拌器枢轴元件延伸，位于上，下三个主要侧面以用于旋转运动。 在不存在凝结的情况下，搅拌器叶片叶片可以响应于外部磁场扫过测试样品。 当搅拌器运动开始时，搅拌器自由移动，启动定时器。 检测到由于凝结而产生的搅拌器运动阻力，测定凝固时间。