公开(公告)号：US5599527A

公开(公告)日：1997-02-04

申请号：US340568

申请日：1994-11-14

Applicant: Donald P. Hsu ,  Rajnish Kohli ,  Michael Prencipe

Inventor： Donald P. Hsu ,  Rajnish Kohli ,  Michael Prencipe

IPC: A61K8/24 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18 ,  A61K7/20 ,  A61K33/40

CPC classification number: A61K8/24 ,  A61Q11/00

Abstract: A storage stable oral composition which is effective against calculus which contains an orally acceptable vehicle having incorporated therein an effective anticalculus combination of about 0.5 to about 2% by weight of a water soluble pyrophosphate salt and about 0.5 to about 3% by weight of a water soluble polyphosphate salt. The presence in the composition of polyvalent metal compounds and fluoride compounds do not affect the stability of the composition as well as reactive ingredients such as peroxide and bicarbonate compounds.

Abstract translation: 一种储存稳定的口腔用组合物，其对于结石有效，其含有口服可接受的载体，其中加入了约0.5至约2重量％的水溶性焦磷酸盐和约0.5至约3重量％水的有效抗结石组合 可溶性多磷酸盐。 在多价金属化合物和氟化物的组成中的存在不影响组合物的稳定性以及反应性成分如过氧化物和碳酸氢盐化合物。

公开(公告)号：US5578293A

公开(公告)日：1996-11-26

申请号：US350309

申请日：1994-12-06

Applicant: Michael Prencipe ,  Michael Burke ,  Suryakant Patel ,  Julie A. Miller

Inventor： Michael Prencipe ,  Michael Burke ,  Suryakant Patel ,  Julie A. Miller

IPC: A61K8/21 ,  A61K8/24 ,  A61K8/365 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18 ,  A61K7/24

CPC classification number: A61Q11/00 ,  A61K8/21 ,  A61K8/24 ,  A61K8/365

Abstract: An aqueous oral care composition containing a stannous ion releasing compound and a combination of a pyrophosphate salt, and an organic acid compound, the combination being present in the composition in an amount sufficient to effectively stabilize the stannous ion concentration.

Abstract translation: 一种含有离子释放化合物的水性口腔护理组合物和焦磷酸盐和有机酸化合物的组合，该组合物以足以有效稳定亚锡离子浓度的量存在于组合物中。

公开(公告)号：US5487906A

公开(公告)日：1996-01-30

申请号：US356804

申请日：1994-12-15

Applicant: Nagaraj Dixit ,  Gary Durga ,  Michael R. Burke ,  Michael Prencipe ,  Suryakant Patel

Inventor： Nagaraj Dixit ,  Gary Durga ,  Michael R. Burke ,  Michael Prencipe ,  Suryakant Patel

IPC: A61K33/24 ,  A61K33/16 ,  A61K7/18

CPC classification number: A61K33/24

Abstract: A method for the preparation of an aqueous stable premix containing a stannous ion releasing compound useful in the manufacture of an aqueous oral care composition containing a stable stannous ion releasing compound which comprises first dissolving the stannous compound in an aqueous solution of critic acid or its alkali metal salt to prepare the aqueous premix to the vehicle of the oral care composition.

Abstract translation: 一种制备含有稳定的亚锡离子释放化合物的水性稳定预混物的方法，其用于制备含有稳定的亚锡离子释放化合物的水性口腔护理组合物，其包括首先将亚锡化合物溶解在批评酸或其碱的水溶液中 金属盐，以将水性预混物制备成口腔护理组合物的载体。

公开(公告)号：US5453265A

公开(公告)日：1995-09-26

申请号：US181525

申请日：1994-01-13

Applicant: Abdul Gaffar ,  Nuran Nabi ,  John Afflitto ,  Drum Stringer ,  Michael Prencipe

Inventor： Abdul Gaffar ,  Nuran Nabi ,  John Afflitto ,  Drum Stringer ,  Michael Prencipe

IPC: A61K8/24 ,  A61K8/34 ,  A61K8/42 ,  A61K8/81 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18

CPC classification number: A61K8/24 ,  A61K8/347 ,  A61K8/42 ,  A61K8/8164 ,  A61Q11/00 ,  A61K2800/87

Abstract: An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.

Abstract translation: 含有口服可接受的载体的口服组合物洁齿剂，约30-75重量％的牙齿可接受的水不溶性抛光剂，基本上不溶于水的非阳离子抗菌抗斑剂如2,4,4'-三氯-2' - 羟基 - 二苯基醚（三氯生）抗菌增强剂，其增强了所述抗菌剂向口腔表面和表面活性剂和/或调味油的输送和保留。

公开(公告)号：US5385729A

公开(公告)日：1995-01-31

申请号：US933851

申请日：1992-08-24

Applicant: Michael Prencipe ,  Angelo Zaccagnino

Inventor： Michael Prencipe ,  Angelo Zaccagnino

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/29 ,  A61K8/34 ,  A61K8/36 ,  A61K8/40 ,  A61K8/60 ,  A61K8/72 ,  A61K8/73 ,  A61K8/81 ,  A61K8/85 ,  A61K8/97 ,  A61Q5/06 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/10 ,  A61K7/06 ,  A61K7/48

CPC classification number: A61K8/042 ,  A61K8/8135 ,  A61K8/8164 ,  A61K8/8182 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/10 ,  A61Q5/06 ,  A61K2800/48 ,  A61K2800/52

Abstract: A personal care composition in the form of a hair or skin-treating gel containing an amount of a synthetic linearly viscoelastic cross-linked polymeric thickening agent, especially a cross-linked methyl vinyl ether/maleic anhydride copolymer, effective to render the composition linearly viscoelastic, and a method of promoting personal care by applying an effective amount of the composition to the hair or skin.

Abstract translation: 一种以毛发或皮肤处理凝胶形式的个人护理组合物，其含有一定量的合成线性粘弹性交联聚合物增稠剂，特别是交联的甲基乙烯基醚/马来酸酐共聚物，其有效地使组成线性粘弹性 以及通过将有效量的组合物施用于毛发或皮肤来促进个人护理的方法。