公开(公告)号：US10252237B2

公开(公告)日：2019-04-09

申请号：US14886661

申请日：2015-10-19

Applicant: Aerosol Dynamics Inc.

Inventor： Susanne Vera Hering ,  Steven Russel Spielman ,  Gregory Stephen Lewis

IPC: B01D53/00 ,  B01J8/08 ,  B01D5/00 ,  G01N15/06

Abstract: An apparatus and method for creating enlarged particles in a flow. The apparatus includes a coiled tube having a tube diameter and a coil diameter, the tube having an input receiving the flow and an output, the tube having a length between the input and the output. A heater heats a first portion of the tube along a first, longitudinal portion of the tube, and a cooler cools a second, longitudinal portion of the tube along at least a second portion of the tube. The method includes heating a first portion of the tube along a first longitudinal portion of the tube, and simultaneously cooling a second portion of the tube along at least a second longitudinal portion of the tube. While heating and cooling, the method includes introducing a flow into an interior of the tube at an input, the flow moving the output.

公开(公告)号：US20160107137A1

公开(公告)日：2016-04-21

申请号：US14886661

申请日：2015-10-19

Applicant: Aerosol Dynamics Inc.

Inventor： Susanne Vera Hering ,  Steven Russel Spielman ,  Gregory Stephen Lewis

IPC: B01J8/08

CPC classification number: B01J8/087 ,  B01D5/0006 ,  B01J2208/00026 ,  B01J2208/00203 ,  G01N15/065 ,  G01N2015/0681

Abstract: An apparatus and method for creating enlarged particles in a flow. The apparatus includes a coiled tube having a tube diameter and a coil diameter, the tube having an input receiving the flow and an output, the tube having a length between the input and the output. A heater heats a first portion of the tube along a first, longitudinal portion of the tube, and a cooler cools a second, longitudinal portion of the tube along at least a second portion of the tube. The method includes heating a first portion of the tube along a first longitudinal portion of the tube, and simultaneously cooling a second portion of the tube along at least a second longitudinal portion of the tube. While heating and cooling, the method includes introducing a flow into an interior of the tube at an input, the flow moving the output.

Abstract translation: 一种用于在流中产生增大的颗粒的装置和方法。 该设备包括具有管直径和线圈直径的盘管，该管具有接收流量的输入和输出，该管具有在输入和输出之间的长度。 加热器沿着管的第一纵向部分加热管的第一部分，并且冷却器沿着管的至少第二部分冷却管的第二纵向部分。 该方法包括沿着管的第一纵向部分加热管的第一部分，同时沿着管的至少第二纵向部分冷却管的第二部分。 在加热和冷却的同时，该方法包括在输入端将流引入到管的内部，流动移动输出。

公开(公告)号：US08459572B2

公开(公告)日：2013-06-11

申请号：US12910705

申请日：2010-10-22

Applicant: Susanne Hering ,  Gregory Lewis ,  Steven R. Spielman

Inventor： Susanne Hering ,  Gregory Lewis ,  Steven R. Spielman

IPC: A62C5/02

CPC classification number: G01N1/2202 ,  G01N1/40 ,  G01N15/065 ,  G01N2001/2223

Abstract: Technology is presented for the high efficiency concentration of fine and ultrafine airborne particles into a small fraction of the sampled airflow by condensational enlargement, aerodynamic focusing and flow separation. A nozzle concentrator structure including an acceleration nozzle with a flow extraction structure may be coupled to a containment vessel. The containment vessel may include a water condensation growth tube to facilitate the concentration of ultrafine particles. The containment vessel may further include a separate carrier flow introduced at the center of the sampled flow, upstream of the acceleration nozzle of the nozzle concentrator to facilitate the separation of particle and vapor constituents.

Abstract translation: 提出了通过冷凝扩大，空气动力学聚焦和流动分离，将精细和超细空气中的颗粒高效浓缩成采样气流的一小部分的技术。 包括具有流动提取结构的加速喷嘴的喷嘴集中器结构可以联接到容纳容器。 容纳容器可以包括水冷凝生长管，以促进超细颗粒的浓缩。 容纳容器还可以包括在采样流的中心引入的单独载体流，在喷嘴浓缩器的加速喷嘴的上游，以便于分离颗粒和蒸汽成分。

公开(公告)号：US08088627B2

公开(公告)日：2012-01-03

申请号：US11008851

申请日：2004-12-10

Applicant: Susanne V. Hering ,  Allen H. Goldstein

Inventor： Susanne V. Hering ,  Allen H. Goldstein

IPC: G01N30/06

CPC classification number: G01N30/12 ,  G01N1/2214 ,  G01N15/065 ,  G01N30/68 ,  G01N30/7206 ,  G01N30/78 ,  G01N2030/128

Abstract: A method and apparatus for the in-situ, chemical analysis of an aerosol. The method may include the steps of: collecting an aerosol; thermally desorbing the aerosol into a carrier gas to provide desorbed aerosol material; transporting the desorbed aerosol material onto the head of a gas chromatography column; analyzing the aerosol material using a gas chromatograph, and quantizing the aerosol material as it evolves from the gas chromatography column. The apparatus includes a collection and thermal desorption cell, a gas chromatograph including a gas chromatography column, heated transport lines coupling the cell and the column; and a quantization detector for aerosol material evolving from the gas chromatography column.

Abstract translation: 一种用于气溶胶原位，化学分析的方法和装置。 该方法可以包括以下步骤：收集气溶胶; 将气溶胶热解吸到载气中以提供解吸的气溶胶材料; 将解吸的气溶胶材料运送到气相色谱柱的头上; 使用气相色谱仪分析气溶胶物质，并在气相色谱柱演化时量化气溶胶物质。 该装置包括收集和热解吸池，气相色谱仪，包括气相色谱柱，耦合电池和色谱柱的加热输送管线; 以及用于从气相色谱柱析出的气溶胶材料的量化检测器。

公开(公告)号：US12234440B2

公开(公告)日：2025-02-25

申请号：US16912486

申请日：2020-06-25

Applicant: Aerosol Dynamics Inc. ,  University of Florida Research Foundation, Incorporated

Inventor： Arantzazu Eiguren Fernandez ,  Gregory Stephen Lewis ,  Steven Russel Spielman ,  Chang-Yu Wu ,  Trevor Benson Tilly

IPC: C12M3/00 ,  C12M1/00 ,  C12M1/12 ,  C12M1/34 ,  C12N5/00

Abstract: An apparatus and method for the delivery and deposition of particles air-liquid-interface (ALI) cell cultures includes a sample inlet coupled to a growth tube having interior walls that are wet. The growth tube is configured to operate at a first temperature along a first length of the tube and a second temperature along a second length positioned between the first length and a growth tube outlet. The apparatus also includes a nozzle plate having a plurality of nozzles. The exposure chamber adapted to hold cell cultures at an air-liquid interface positioned underneath the plurality of nozzles and a temperature regulator adapted to control a temperature of the exposure chamber. The apparatus also includes a controller including instructions operable to cause the controller to maintain a relative humidity within the exposure chamber by controlling at least the second temperature of the growth tube and the temperature of the exposure chamber.

公开(公告)号：US11029240B2

公开(公告)日：2021-06-08

申请号：US16159604

申请日：2018-10-12

Applicant: Aerosol Dynamics Inc.

Inventor： Susanne Vera Hering ,  Steven Russel Spielman ,  Gregory Stephen Lewis

IPC: G01N21/00 ,  G01N15/06 ,  F28B1/02 ,  F28B11/00

Abstract: A wick liquid sensor suitable for use in a particle condensation device is provided. The sensor includes a light source configured to illuminate a surface of the wick. A detector is configured to detect wick reflected light from the light source and determine the intensity of reflected light. The wick is formed from a porous media that is wettable by the liquid, and becomes translucent when filled with the liquid. The amount of reflectivity decreases as the saturation content of the liquid in the wick increases.

公开(公告)号：US09821263B2

公开(公告)日：2017-11-21

申请号：US14318126

申请日：2014-06-27

Applicant: Aerosol Dynamics Inc.

Inventor： Susanne V. Hering ,  Gregory S. Lewis ,  Steven R. Spielman

IPC: B01D53/00 ,  B01D5/00 ,  G01N15/06 ,  G01M15/10 ,  B01D53/14 ,  H04L12/863 ,  G01N15/00 ,  G01N15/14

CPC classification number: B01D53/002 ,  B01D5/0009 ,  B01D53/1475 ,  B01D2257/504 ,  G01M15/102 ,  G01N15/065 ,  G01N2015/0038 ,  G01N2015/1481 ,  H04L47/50 ,  Y02T10/47

Abstract: This technology relates to the enlargement by water condensation in a laminar flow of airborne particles with diameters of the order of a few nanometers to hundreds of nanometers to form droplets with diameters of the order of several micrometers. The technology presents several advanced designs, including the use of double-stage condensers. It has application to measuring the number concentration of particles suspended in air or other gas, to collecting these particles, or to focusing these particles.

公开(公告)号：US08801838B2

公开(公告)日：2014-08-12

申请号：US13218393

申请日：2011-08-25

Applicant: Susanne V. Hering ,  Gregory S. Lewis ,  Steven R. Spielman

Inventor： Susanne V. Hering ,  Gregory S. Lewis ,  Steven R. Spielman

IPC: B01D53/00

CPC classification number: B01D53/002 ,  B01D5/0009 ,  B01D53/1475 ,  B01D2257/504 ,  G01M15/102 ,  G01N15/065 ,  G01N2015/0038 ,  G01N2015/1481 ,  H04L47/50 ,  Y02T10/47

Abstract: This technology relates to the enlargement by water condensation in a laminar flow of airborne particles with diameters of the order of a few nanometers to hundreds of nanometers to form droplets with diameters of the order of several micrometers. The technology presents several advanced designs, including the use of double-stage condensers. It has application to measuring the number concentration of particles suspended in air or other gas, to collecting these particles, or to focusing these particles.

Abstract translation: 该技术涉及通过直径为几纳米至几百纳米的空气中的颗粒的层流中的水冷凝扩大以形成直径为几微米级的液滴。 该技术提供了几种先进的设计，包括使用双级冷凝器。 它可用于测量悬浮在空气或其他气体中的颗粒的数量浓度，以收集这些颗粒或聚焦这些颗粒。

公开(公告)号：US20140033915A1

公开(公告)日：2014-02-06

申请号：US14043455

申请日：2013-10-01

Applicant: Aerosol Dynamics Inc.

Inventor： Susanne Vera Hering ,  Steven Russel Spielman ,  Gregory Stephen Lewis ,  Nathan Michael Kreisberg

IPC: B01D47/00

CPC classification number: B01D47/00 ,  B01D5/0009 ,  B01D53/1475 ,  B01D53/18 ,  F25J3/08 ,  F25J2200/70 ,  G01M15/102 ,  G01N15/06 ,  G01N15/065 ,  G01N2015/0038 ,  G01N2015/1481

Abstract: A system and method for particle enlargement with continuously wetted wicks includes a container into which a flow of particle-laden air is introduced in a laminar manner through an inlet and to an outlet. The container has a first section, a second section and a third section though which the particle-laden air flows between the inlet and the outlet. The temperature of the second section is warmer than that of the first section at the inlet and the third section at the outlet. In one embodiment, a continuous wick spanning an interior wall of the first second, second section and third section, said wick being capable of internally transporting liquid water along its length is provided. Alternatively, a wick characterized by a bubble point pressure has one side in contact with air and an opposing side mounted adjacent to the interior wall of a housing with a gap formed between the wick and the housing, wherein the wick is used with a water reservoir such that the pressure difference between the air flow and the water filled gap is less than the bubble point pressure of the wick material.

Abstract translation: 具有连续润湿的芯的颗粒增大的系统和方法包括容器，通过入口和出口以层流方式将颗粒载气的空气流引入该容器中。 容器具有第一部分，第二部分和第三部分，通过该第一部分，颗粒载满的空气在入口和出口之间流动。 第二部分的温度比入口处的第一部分和出口处的第三部分的温度更暖。 在一个实施例中，提供横跨第一第二，第二部分和第三部分的内壁的连续的芯，所述芯能够沿其长度内部输送液态水。 或者，以泡点压力为特征的芯具有与空气接触的一侧，并且相邻侧安装在壳体的内壁附近，在芯和壳体之间形成有间隙，其中芯与水槽一起使用 使得空气流与填充水的间隙之间的压差小于芯材料的泡点压力。

公开(公告)号：US20110095095A1

公开(公告)日：2011-04-28

申请号：US12910705

申请日：2010-10-22

Applicant: Susanne V. Hering ,  Gregory S. Lewis ,  Steven R. Spielman

Inventor： Susanne V. Hering ,  Gregory S. Lewis ,  Steven R. Spielman

IPC: B05B1/00

CPC classification number: G01N1/2202 ,  G01N1/40 ,  G01N15/065 ,  G01N2001/2223

Abstract: Technology is presented for the high efficiency concentration of fine and ultrafine airborne particles into a small fraction of the sampled airflow by condensational enlargement, aerodynamic focusing and flow separation. A nozzle concentrator structure including an acceleration nozzle with a flow extraction structure may be coupled to a containment vessel. The containment vessel may include a water condensation growth tube to facilitate the concentration of ultrafine particles. The containment vessel may further include a separate carrier flow introduced at the center of the sampled flow, upstream of the acceleration nozzle of the nozzle concentrator to facilitate the separation of particle and vapor constituents.

Abstract translation: 提出了通过冷凝扩大，空气动力学聚焦和流动分离，将精细和超细空气中的颗粒高效浓缩成采样气流的一小部分的技术。 包括具有流动提取结构的加速喷嘴的喷嘴集中器结构可以联接到容纳容器。 容纳容器可以包括水冷凝生长管，以促进超细颗粒的浓缩。 容纳容器还可以包括在采样流的中心引入的单独载体流，在喷嘴浓缩器的加速喷嘴的上游，以便于分离颗粒和蒸汽成分。