摘要:
Strains of the genus Corynebacterium which combine resistance to feedback inhibition by S-(2-aminoethyl)-L-cysteine with methionine sensitivity and additionally may require proline or arginine, produce a large amount of L-lysine by fermentation of otherwise conventional culture media.
摘要:
Polymers whose backbone includes aspartic or glutamic acid units, peptide-linked by their amino and Alpha -carboxyl groups, improve greatly in wet strength when contacted in a liquid medium with organic isocyanates until a sufficient number of the omega -carboxyl groups in the side chains of the polymer is converted to groups of the formula - CO - NH - C * by reaction with NCO groups of the isocyanate. Compounds having two or more NCO groups may cause cross linking. The high permeability of the glutamic or aspartic acid polymers to moisture, oxygen, carbon dioxide, and solutes in aqueous solutions is not significantly impaired, and may be enhanced by conversion of the omega -carboxyl groups, while wet strength is sharply increased, thereby improving utily of the polymers as dialysis membranes and in like applications.
摘要:
Uridine, cytidine, and derivatives thereof arrived at by substitution in positions 4, 5 and 5'' are converted to the corresponding 2,2''-anhydro compounds by reaction with cyclic lower alkylene and alkenylene esters of carbonic acid. The anhydro compounds are hydrolyzed to arabinofuranosylpyrimidine derivatives in a basically known manner. The latter as well as the anhydro compounds are known physiologically active agents and/or intermediates in the synthesis of such agents.
摘要:
1. AN N-SUBSTITUTED AMINO ACID SELECTED FROM THE GROUP CONSISTING OF N-B-NAPHTHYLAMINOMETHYLLEUCINE, N-2-FLUOROENESULFONLPHENYLALANINE, N-B-NAPHTHYLAMONOMETHYLTHREONINE, AND N-9-FLUORENYLACETYLPHENYLALANINE.
摘要:
A STABLE, CLEAR HOMOGENEOUS SOLUTION OF A POLYALKYL GLUTAMATE AND OF AN ELASTOMER IS PRODUCED BY POLYMERIZING AN OPTICALLY ACTIVE Y-LOWER-ALKYL GLYTAMATE N-CARBOXY ANHYDRIDE IN A SOLUTION OF THE ELASTOMER, IF THE ELASTOMER IS INERT TO THE ANHYDRIDE AND TO THE POLYALKYL GLYTAMATE PRODUCED UNDER THE POLYMERIZATION CONDITIONS, AND THE PPOLYALKYL GLUTAMATE IS SOLUBLE IN THE SOLUTION. SHAPED OBJECTS AND COATINGS COMBINING THE DESIRED PROPERTIES OF BOTH POLYMERS MAY BE PREPARED FROM THE SOLUTIONS.
摘要:
Proline-producing, artificially induced mutants of Brevibacterium and Corynebacterium produce more proline than the respective parent strains if the growth of the mutants is less inhibited by sulfa drugs than that of the parent strains.
摘要:
MICROORGANISMS OF THE GENERA BREVIBACTERIUM, CORYNEBACTERIUM, AND ARTHROBACTER ARE EXPOSED TO MUTAGENIC CHEMICAL AGENTS OR TO IONIZING RADIATION, AND THE EXPOSED ORGANISMS ARE SCREENED FOR THE PRESENCE OF MUTANTS CAPABLE OF PRODUCING L-HISTIDINE BY AREOBIC FERMENTATION OF CONVENTIONAL CULTURE MEDIA. THE BEST MUTANT STRAIN OF SELECTED PRODUCES 4.3 G. 1. L-HISTIDINE IN THE BOTH WITHIN 48 HOURS. THE HISTIDINE IS RECOVERD IN GOOD YIELDS BY ABSORPTION FROM THE BROTH ON ION EXCHANGE RESIN.
摘要:
THE ENZYMES PRESENT IN AN ENZYME-BEARING DETERGENT COMPOSITION ARE STABILIZED BY SMALL AMOUNTS OF N-ACYL AMINO ACIDS WHOSE ACYL GROUPS ARE DERIVED FROM SATURATED OR UNSATURATED FATTY ACIDS HAVING 6 TO 20 CARBON ATOMS, AND THE ENZYMES ARE ALSO STABLE IN DETERGENTS IN WHICH THE N-ACYL AMINO ACIDS ARE THE PRIMARY SURFACTANT INGREDIENTS.